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Journal : Jurnal Pijar MIPA

Antibacterial Activity Test of the Combination of Methanol Extract of Arumanis Mango Leaves (Mangifera indica L) and Taro Leaves (Colocasia esculanta L) on Escherichia coli Bacteria Causes of Diarrhea Diseases Kumalasari, Siska; Fitriyati, Laeli; Rahayu, Titi Pudji; Kiromah, Naelaz Zukhruf Wakhidatul
Jurnal Pijar Mipa Vol. 19 No. 1 (2024): January 2024
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v19i1.5850

Abstract

Arumanis mango leaves (Mangifera indica L) and taro leaves (Colocasia esculanta L) are plants that have the potential to be antibacterial and can be used as an alternative to treat infectious diseases caused by bacteria. Arumanis mango leaves contain secondary metabolite compounds, including flavonoids, alkaloids, steroids, polyphenols, tannins, and saponins, and taro leaves contain secondary metabolite compounds in the form of saponins, tannins, flavonoids, formic acid, glucosides, citric acid, and several minerals. Secondary metabolite compounds that have potential as antibacterials are flavonoids and tannins. This study aims to determine the antibacterial activity of a combination of methanol extracts of arumanis mango leaves (Mangifera indica L) and taro leaves (Colocasia esculanta L) against Escherichia coli bacteria. The research was carried out starting from the plant determination and preparation of simplisia, extraction, phytochemical screening of extracts and KLT tests, and antibacterial testing using the disc paper method. The concentration series of extract combinations used are 6.25%, 12.5%, and 25%. The antibacterial test results of the combination of arumanis mango leaf extract (Mangifera indica L) and taro leaf (Colocasia esculanta L), which showed the highest inhibition zone diameter was at a concentration of 6.25% (1:1), a concentration of 12.5% (1:2). At a concentration of 25% (2:1). From the results of this study, a single extract of arumanis mango leaves and taro leaves with a concentration of 6.25%; 12.5%; 25% and a combination of extracts in a ratio of 1:1. 1:2, 2:1, which has potential antibacterial activity against Escherichia coli bacteria, so that further research can be carried out by utilizing a combination of arumanis mango leaf extracts and taro leaves and as a source of information and insight into the combination of arumanis mango leaves and taro leaves that have antibacterial properties.
Formulation and Physical Evaluation of Papaya Leaf (Carica papaya L.) Ethyl Acetate Fraction Cream Preparation as Anti Acne Against Propionibacterium acne Bacteria Farda, Zais; Rahayu, Titi Pudji; Kiromah, Naelaz Zukhruf Wakhidatul
Jurnal Pijar Mipa Vol. 19 No. 2 (2024): March 2024
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v19i2.6146

Abstract

Acne or acne vulgaris is a disease in the form of inflammation of multiple sebaceous glands caused by the bacteria Propionibacterium acne. Papaya leaves are a plant that can potentially be used as an acne treatment. To determine the antiacne activity of papaya leaf ethyl acetate fraction cream preparations caused by Propionibacterium acne bacteria. The ethyl acetate fraction of papaya leaves are made into a cream preparation with varying concentrations of ten, fifteen, and twenty percent. The results of the cream preparation test met the physical property standards. Still, the viscosity in formulation three did not meet the standards, and formulas two and three did not meet the cream stability test standards. Antibacterial tests show that all formulas have inhibitory power against bacteria. The average inhibition zone results in formula one, formula two, and formula three were 4.99 ± 0.48 mm, 6.85 ± 0.48 mm and 10.12 ± 1.42 mm. Formula One papaya leaf fraction cream fulfills all the physical characteristics of the preparation. All papaya leaf ethyl acetate fraction cream preparations are antibacterial against Propionibacterium acne. So, research can be developed using the ethyl acetate fraction of papaya leaves in various preparations, and activity tests against other bacteria can be carried out.
Co-Authors Afif Hussein Kholid Bahrisy Agung Setiawan agung setiawan Ainni, Ayu Nissa Arnika Dwi Asti Asriani Tagawuningsih Astri Ayu Febri Yuliani Awalia, Luluk Azhari, Tasya Khairunisa Azizah, Rizki Nur Bahrisy, Afif Hussein Kholid Billa, Zalsa Chondrosuro Miyarso Chondrosuro Miyarso Churrohmah, Syifa Condro Suro Miyarso Dwiki Fitri EkaWuri Handayani Eko Prasetyo Ery Purwanti Ery purwanti Evi Marlina Farda, Zais Fatimah, Ayu Febrialfiyan, Sukma Edhie Fiana, Fuan Maharani Fitriyati, Laeli Fuan Maharani Fiana Hamzah, Hasyrul Hasanah, Saniati Herniyatun Herniyatun, H Inayah, Siti Khobiratul Majidah Khuluk, Khusnul Khuluq, Muh Husnul Khusnul Khuluk Krisdiyanti, Yayu Kumalasari, Siska Kurniasih Kurniasih Kurniasih Kurniasih L Ledianasari L Ledianasari Laeli Fitriyati Laeli Fitriyati Laeli Fitriyati Ledianasari, L Majidah, Khobiratul Melisa, Leni Miyarso, Chondrosuro Miyarso, Condro Suro Muchromin Muchromin Mulyana, Satria Eta Nafarina, Eka Rezki Tri Ningsih, Eka Ratna Pamungkas, Anindya Arya Pratama, Dimas Aji pratiwi, lia nur Pratiwi, Noviani Pravitasari, Rokhania Eka Rachman Aziz, Dwinuari Rachmawati, Indah Raharjo, Rahmat Budhi Rahayu, Titi Pudji Rahayu, Venny Septiana Rahmat Ismail Rahmawati, Rahmawati Sadam Husein Sadam Husein Sadam Husein Saputra, Aditya Mahe Septiani, Sinta Wahyu Sholihah, Rizka Hidayatus Sinta Wahyu Septiani Sinta Wahyu Septiani Sugeng Supriyanto Supriyanto, Sugeng Tagawuningsih, Asriani Tangawuningsih, Asriani Titi Pudji Rahayu Titi Pudji Rahayu TITI PUDJI RAHAYU Tri Cahyani Widiastuti Tri Cahyani Widiastuti Tri Cahyani Widiastuti Tri Cahyani Widiastuti Uswatun Hasanah USWATUN KHASANAH Utomo, Hijan Dzulfadhli Wahyu Rahmatulloh Wahyuni, Septi Widiastuti, Tri Cahyani Yayu Krisdiyanti Yayu Krisdiyanti Yusuf Kurniawan Yusuf Kurniawan Zubaidah, Siti Nur