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Pengaruh Pemberian Sinbiotik, Probiotik, dan Prebiotik terhadap Depresi, Stres, dan Mood pada Orang Dewasa: Systematic Review dan Meta-Analisis: Effects of Synbiotic, Probiotic, and Prebiotic Supplementation on Depression, Stress, and Mood in Adults: A Systematic Review and Meta-Analysis Habibi, Nur Ahmad; Gusnedi, Gusnedi; Nindrea, Ricvan Dana; Hasniyati, Rina; Afriza, Renita; Rusydi, Riska; Yuska, Defniwita; Darningsih, Sri; Zulkifli, Zulkifli; Ismanilda, Ismanilda; Handayani, Marni; Utami, Citra Tristi; Umar, Hermita Bus; Dwiyanti, Defriani; Yuniritha, Eva
Amerta Nutrition Vol. 9 No. 1SP (2025): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 5th Amerta Nutrition Conferenc
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i1SP.2025.420-430

Abstract

Background: Psychobiotics, including probiotics, prebiotics, and synbiotics, have been proposed to improve mental health through modulation of the gut–brain axis. However, findings from randomized controlled trials (RCTs) remain inconsistent, Objectives: To systematically review and synthesize evidence on the effects of probiotics, prebiotics, and synbiotics on depression, stress, and mood in adult populations. Methods: A comprehensive search was conducted in PubMed, yielding 531 articles, of which 14 RCTs met the inclusion criteria. Risk of bias was assessed using the Cochrane Risk of Bias Tool. Meta-analyses were performed using both fixed- and random-effects models in RevMan. The study protocol was registered in PROSPERO (CRD420251103338). Discussions: Ten RCTs (n = 881) assessing depression did not show consistent benefits (SMD = –0.72; 95% CI: –1.42 to –0.01; p-value = 0.05; I² = 96%). Six RCTs (n = 444) evaluating stress also showed non-significant effects (MD = –1.35; 95% CI: –3.70 to 1.01; p-value = 0.26; I² = 73%). Conversely, six RCTs (n = 376) demonstrated significant improvements in mood (MD = 0.73; 95% CI: 0.25 to 1.20; p-value = 0.003; I² = 75%). Meta-regression indicated that larger sample sizes were associated with more consistent improvements in mood (p-value = 0.04). Sensitivity analyses confirmed the stability of the findings, and no evidence of publication bias was detected. Conclusions: Probiotic, prebiotic, and synbiotic supplementation may provide beneficial effects on mood and could serve as a potential nutritional intervention to enhance psychological health. However, effects on depression and stress inconsistent.
The Effect of Health Education on the Behavior of Elderly with Hypertension Asni Hasanuddin; Muh Khidri Alwi; Ricvan Dana Nindrea; Astuti Astuti; Nilam Fitriani Dai; Andi Maryam; Ardiansah Hasin; La Ode Asrianto
Jurnal Penelitian Pendidikan IPA Vol 9 No 9 (2023): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i9.4506

Abstract

Education is one way that can be used to increase one's knowledge. Education can be given in various fields, including health. The purpose of this study was to determine the effect of Health Education on increasing the knowledge, attitudes and behavior of elderly people with hypertension in the Pangkajene Health Center area in 2023. This type of research used a quantitative method with a pre-experimental design study with pre-test and post-test design treatment, while the population was patients 90 people who suffer from hypertension at the Pangkajene Health Center use total sampling. The results of this study used the Wilcoxon test analysis. Knowledge was -8.132 and a significant value was 0.000 (p<0.05), Attitude was -8165 and a significant value was 0.000 (p<0.05), and Behavior was -8267 and a significant value was 0.000 ( p<0.05), there was a significant difference in the results of the Health Education pretest and posttest on the attitudes of the elderly with hypertension in the Pangkajene Health Center area. The results of this study indicate that there is an effect of Health Education on the attitude of the elderly who experience hypertension in the Pangkajene Health Center area. The conclusion of the study showed that there was an effect of Health Education on the knowledge, attitudes and behavior of elderly people with hypertension in the Pangkajene Health Center area. it is expected that the puskesmas will carry out home care because elderly people with hypertension cannot carry out health checks because there is no family to take them to health services because they are busy with their daily activities.
Influence Factors Nutritional Needs in the Elderly in Marginalized Communities: Pengaruh Faktor yang Mempengaruhi Kebutuhan Status Gizi Lansia di Pulau Kodingareng Kota Makassar Andi Maryam; Andi Elis; Asni Hasanuddin; Muh Khidri Alwi; Ahmad Syaekhu; Ricvan Dana Nindrea
Jurnal Penelitian Pendidikan IPA Vol 9 No 9 (2023): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i9.4570

Abstract

Nutritional problems are caused by rapid degradation which causes changes in nutritional status. This study aims to determine the factors that affect the nutritional needs of the elderly on Kodingareng Island in 2023. The research design was carried out in a descriptive-correlative way with a cross-sectional study approach with 49 respondents. The data collection tool is in the form of a questionnaire in the form of a dichotomy. The sample collection technique used is total sampling. The research results show that there is a relationship that influences nutritional needs on the nutritional status of the elderly, namely physical activity, mental condition, depression, disease treatment, and biological decline with a p-value <0.05. The conclusion is obtained that the nutritional status of the elderly is in the normal category, so it is recommended for the community to optimize attention to the food consumed so that they remain at normal nutritional status as well as in administering drugs so that absorption is more optimal.