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All Journal Jurnal Kesehatan Masyarakat Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Psikologi Pendidikan dan Konseling Jurnal Biologi Tropis Indonesia Journal of Physical Medicine and Rehabilitation Cendana Medical Journal Indonesia Journal Physical Medicine and Rehabilitation Jurnal Psikologi Pendidikan dan Konseling Innovative: Journal Of Social Science Research Galen: Jurnal Ilmu Farmasi dan Kesehatan
Deri Riskiyanti Tallo Manafe
Universitas Nusa Cendana
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Veterinary Other

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The Relationship Between Primary Dysmenorrhea And Sleep Quality In Students Of The Faculty Of Medicine, University Of Nusa Cendana Kelore, Imelda Martha Somi; Sihotang, Jojor; Folamauk, Conrad Liab H.; Manafe, Derri Tallo
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.17400

Abstract

When experiencing menstruation, it is often accompanied by pain which is commonly called dysmenorrhea. Primary dysmenorrhea experienced can cause discomfort both during activities and at rest so that it can affect sleep quality. The sleep quality of medical students is bad, apart from the lecture burden, it is suspected that it can also be influenced by the intensity of pain, such as when experiencing primary dysmenorrhea. To determine the relationship between primary dysmenorrhea and sleep quality in students of the Faculty of Medicine, University of Nusa Cendana. This research is an observational analytic study with a cross sectional design in students of the Faculty of Medicine, University of Nusa Cendana. Data was conducted by filling out the primary dysmenorrhea questionnaire and Pittsburgh Sleep Quality Index (PSQI) questionnaire by 106 respondents who met the inclusion criteria. Sampling was done by using stratified random sampling technique. The result was analyzed univariate and bivariate using Phi Correlation test. Data from 106 respondents showed that 63.2% of respondents experienced primary dysmenorrhea and as many as 36.8 respondents did not experience primary dysmenorrhea. For sleep quality, 80.2% of respondents had poor sleep quality and 19.8% of respondents had good sleep quality. In this study, it was found that more respondents had primary dysmenorrhea with poor sleep quality than good sleep quality. The results of the bivariate analysis with the Phi Correlation test showed the results of p value=0.520 (p> 0.05). There is no significant relationship between primary dysmenorrhea and sleep quality in students of the Faculty of Medicine, University of Nusa Cendana.
Testing The Laxative Activity of Utasupe Leaf Juice from The Ende Region on White Rats (Rattus novergicus) Loperamid Induced Constipation Model Hendrik, Einstein Daud Victor; Nurina, Rr. Listyawati; Manafe, Derri Tallo; Rini, Desi Indria; Dean, Muhajirin
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11608

Abstract

Constipation is a problem in the pattern of elimination due to the presence of dry or hard feces passing through the large intestine, while a laxative is a substance that can provide stimulation of intestinal peristalsis as a reflex of direct stimulation of the intestinal wall that can facilitate defecation. Many medicinal plants can treat constipation, one of which is Utasupe. Utasupe is a vegetable plant originating from the Ende region. In Ende, Utasupe is believed to facilitate bowel movements, so people often consume Utasupe. This study aims to determine the laxative effect of Utasupe leaf juice from Ende region on loperamide-induced male white rats (Rattus novergicus). The study was conducted experimentally on 30 Sprague daley strain white rats aged 8-12 weeks. The parameter for testing the laxative effect was the defecation pattern, while the observed parameter was the frequency of defecation every hour for 8 hours. Utasupe leaf juice was administered orally at a dose of 125 mg/mL, 250 mg/mL and 500 mg/mL, as a comparison negative control (Na-CMC) and positive control (Bisacodyl) were used. The results showed that the administration of Utasupe leaf juice at a dose of 250 mg/mL had a laxative effect on male white rats. Utasupe leaf juice has laxative activity in white rats (Rattus novergicus). The time required for defecation to occur after being given Utasupe leaf juice from the Ende area in white rats (Rattus novergicus) is one hour with the most effective dose is 250 mg/mL.
Perbandingan Pemberian Air Rebusan Biji Ketumbar dengan Air Kelapa terhadap Kadar Kreatinin Serum pada Penderita Pre-Hipertensi Alfa Julian Lulan; Derri R. Tallo Manafe; I Made Artawan; Arley S. Telussa
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2026): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v2i1.195

Abstract

Ginjal merupakan organ saluran kemih yang memiliki  berbagai fungsi diantaranya menyaring sisa hasil metabolisme dan toksin dari dalam darah yang kemudian dikeluarkan lewat urine. Kondisi meningkatnya tekanan darah merupakan salah satu faktor yang dapat memperburuk fungsi dan kerja ginjal. Salah satu tanda terjadi perburukan fungsi ginjal adalah dengan meningkatnya kadar kreatinin serum dalam darah. Penggunaan bahan alami seperti pemberian air rebusan biji ketumbar dan air kelapa dapat menjadi salah satu upaya nonfarmakologis untuk menurunkan kadar kreatinin serum dalam darah. Tujuan : Penelitian ini bertujuan untuk mengetahui perbedaan efektivitas dari pemberian air rebusan ketumbar dan air kelapa dengan frekuensi satu kali sehari selama satu minggu terhadap perubahan kadar kreatinin serum. Matode : Penelitian ini menggunakan metode penelitian Quasi Eksperimental, dengan rancangan penelitian pre test – post test with control group design. Sampel penelitian berjumlah 48 pendidik dan tenaga kependidikan Universitas Nusa Cendana yang telah memenuhi kriteria inklusi dan eksklusi. Sampel dibagi menjadi tiga kelompok yaitu kelompok kontrol (kelompok 1) yang tidak diberi perlakuan, kelompok intervensi air rebusan ketumbar (kelompok 2) dan kelompok intervensi air kelapa (kelompok 3). Kelompok 2 dan kelompok 3 diberikan intervensi satu kali setiap hari selama satu minggu. Data penelitian akan diuji menggunakan uji paired t-test dan uji one way anova untuk membandingan nilai antara kelompok. Hasil : Terdapat perubahan signifikan pada nilai pre test dengan nilai post test  pada kelompok intervensi air rebusan biji ketumbar dengan p value=0,035. Sedangakan pada kelompok air kelapa dengan p value=0,270 dan pada kelompok kontrol dengan p value=0,882 tidak ada perubahan yang signifikan pada nilai pre test dengan nilai post test-nya. Berdasarkan hasil uji one way anova tidak didapatkan perbedaan yang signifikan antara nilai post test ketiga kelompok dengan p value=0,839.  Kesimpulan : Tidak ada perbedaan efektivitas antara kelompok air rebusan biji ketumbar dengan air kelapa terhadap kadar kreatinin serum pada penderita pre-hipertensi.
Co-Authors Alfa Julian Lulan Amat, Anita Lindesni Shinta Anggraini, Thalitha Ayu Anita Lidesna Shinta Amat Aprio Ngga, Yoseph Mariano Aristia, Lintang Briliana Arley S. Telussa Bao, Maria Melania Nogo Br. Damanik, Efrisca Meliyuita Christina Olly Lada Dally, Juan Simon Imanuel Dariyanti, Putu Desy Widia Dyah G. R. Kareri Dyah Gita Rambu Kareri Eko Novanto Nurismail Fanggidae, Eunike Hosalien Folamauk, Conrad Liab Hendricson Ganggut, Maria Claudia Novitasari Habut, Maria Alberthin Hadi, Giovani Rizaldo Hendrik, Einstein Daud Victor Hutasoit, Regina Marvin I Made Artawan I Made Artawan Idawati Trisno Ika Febianti Buntoro Jojor Sihotang Kareri, Dyah Gita Rambu Kause, Marthen Kedang, Elisabeth Flora S. Kelore, Imelda Martha Somi Koamesah, S.M.J Lape, Antonius Rianto Putra Lidia, Kartini Maria Agnes Etty Dedy Maria Kurniati Ester Payon Monekaka, Norbert R.S. Ndolu, Ronaldo Agustov Nenoliu, Sonia Ngara, Cydri Anggreny Rade Dendo Nurina, Rr. Listyawati PAKAN, PRISCA DEVIANI Prasetyastuti Priambada, Ignasius Bima Rambu Kareri, Dyah Gita Rante, Su Djie To Ratu, Kristian Rini, Desi Indria Sagita, Sidarta Sasputra, I Nyoman Sengi, Tekla Windyanita Setianingrum, Elisabeth Levina Sari Setiawan, I Made Buddy Songkares, Adelaida Olga Malobo Woda, Rahel Rara Wungouw, Herman Pieter Louis Yudistira, Dewa Gede Eka Zefania, Zefania