cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Muhammad Sulaiman Zubair
Contact Email
sulaiman_zubair80@yahoo.co.id
Phone
+6285242083654
Journal Mail Official
jurnalgalenika.farmasiuntad@gmail.com
Editorial Address
Jurusan Farmasi Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Tadulako
Location
Kota palu,
Sulawesi tengah
INDONESIA
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy)
Published by Universitas Tadulako
ISSN : 24427284     EISSN : 24428744     DOI : https://doi.org/10.22487/j24428744
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (E-ISSN: 2442-8744) (p-ISSN: 2442-7284), is an open access journal (print and e-journal) focusing on the scientific works in the field of Pharmacy and Pharmaceutical Science. The articles of this journal are published every six months, that is March and October (2 issues per year). This journal is developed by Department of Pharmacy, Faculty of Mathematics and Natural Science, Tadulako University and has been identified in Crossref with the DOI Number : 10.22487/j24428744. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) has been accredited by Kemenristekdikti as Sinta 3 starting from Volume 5 No 1 2019.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 247 Documents
 13   14   15   16   17 
Pemanfaatan Ekstrak Etanol Teh Hijau (Camellia sinensis L.) sebagai Chelating Agent Logam Berat Cu dengan Metode SSA: Utilization of 96% Ethanol Extract of Green Tea (Camellia sinensis L.) as Chelating Agent For Heavy Metal of Cu With AAS Method Lindawati, Novena Yety; Anggraini, Riska
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15198

Abstract

This research was conducted to determine the ability of ethanol extract of green tea (Camellia sinensis L.) as a chelating agent for heavy metal of Cu. Green tea extraction was carried out by maceration method using 96% ethanol solvent. The ethanol extract of green tea was further tested for phytochemical screening. Analysis of the reduction in total heavy metal content of 10 ppm Cu was measured with an Atomic Absorption Spectrophotometer (AAS) at a wavelength of 324,8 nm. The ethanol extract of green tea (Camellia sinensis L.) was made in series of concentrations of 3 ppm, 6 ppm, 12 ppm and 15 ppm. The results showed that ethanol extract of green tea (Camellia sinensis L.) containing alkaloids, flavonoids, phenolics, tannins, saponins and triterpenoids. The average concentration value of ethanol extract of green tea in reducing Cu metal up to 50% (EC50) was 12,26 ppm with coefficient of variation 0,26%.
Pengaruh Media Perebusan Terhadap Komposisi Mineral Kerang Air Tawar Meti (Batissa violacea Lamarck, 1818): Boiling Media Effect on Mineral Composition of Meti Fresh Water Mussels (Batissa violacea Lamarck, 1818) Handayani, Kiki Rizki; Yuyun, Yonelian; Jamaluddin
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15199

Abstract

This research aims were to analyzed mineral composition of fresh and processed meti freshwater mussels (Batissa violacea Lamarck,1818) and to know the effect of boiling media on the mineral composition with various added boiling media conditions that are water, NaCl 1%, and acetic acid 0.5%. Mineral compositions were tested with microwave digestion and Inductively Coupled Plasma Mass Spectrometry (ICP-MS) method. Mineral composition of fresh mussel were consisted of calcium (Ca) 10412 mg/kg, cobalt (Co) 0,182 mg/kg, copper (Cu) 3,54 mg/kg, magnesium (Mg) 345 mg/kg, mangan (Mn) 13,6 mg/kg, phosphor (P) 7753 mg/kg, potassium (K) 1163 mg/kg, sodium (Na) 291 mg/kg, and zinc (Zn) 44,2 mg/kg. The results of research on freshwater mussels in boiling media of water, NaCl 1%, and acetic acid 0.5% gave effect on the levels of minerals of calcium (Ca), magnesium (Mg), phosphor (P), potassium (K), sodium (Na ), cobalt (Co), copper (Cu), mangan (Mn) and there is no effect on the levels of zinc (Zn).
Immunomodulatory Activity of Xestospongia sp. Ethanolic Extract Towards Interferon-gamma (IFN- γ) and Tumor Necrosis Factor-alpha (TNF-α) Levels in Wistar Male Rats Fristiohady, Adryan; Jumadil; Wahyuni; Malaka, Muh. Hajrul; Harnita, Wa Ode; Sadarun, Baru; Yodha, Agung Wibawa Mahatva; Saripuddin; Purnama, La Ode Muhammad Julian; Sahidin, Idin
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15231

Abstract

Xestospongia sp. is one of marine sponge belongs to demosponges class that mainly found in Southeast Sulawesi and the secondary metabolites contained in Xestospongia sp. suspected to have immunomodulatory activity. A previous study exhibited the immunomodulatory of Xestospongia sp. ethanolic extract (XEE) at dose of 300 and 400 mg/Kg BW by affecting the phagocytic activity of macrophages. Thus, this study aims to investigate the effect of XEE towards interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) at dose of 300 and 400 mg/Kg BW. Wistar male rats are divided into 4 groups (n=6) randomly and treated for 7 days orally each as follow: group I (XEE dose of 300 mg/KgBW); group II (XEE dose of 400 mg/KgBW); group III (0.5% NaCMC); and group IV (commercial phylantii extract). On day 8, animals were infected with Staphylococcus aureus and left for 1 hour. Animals were sacrificed and the blood was drawn by cardiac puncture (3 mL), followed by analyzed under ELISA Kit for IFN-γ and TNF-α. Collected data were analyzed statistically using SPSS®. The IFN-γ levels obtained were 350.113; 392.970; 118.416; and 61.958 ρg/mL, respectively and the TNF-α were 2808; 1308; 778; and 845.5 ρg/mL, respectively. According to results obtained, both doses of XEE are affecting the IFN-γ and TNF-α levels (p<0.05) compared to group III as negative control, and group IV as positive control. As conclusion, XEE of both doses is increasing IFN-γ and TNF-α levels of animals that respond to phagocytic activity
Burns Wound Healing Activity of Extract Gel Formula of Lidah Buaya (Aloe vera) and Senggani Leaf (Melastoma polyanthum): Aktivitas Penyembuhan Luka Bakar Formula Gel Ekstrak Lidah Buaya (Aloe vera) dan Daun Senggani (Melastoma polyanthum) Wahyuningsih, Sri; Syamsu, A. Suparlan Isya; Awaluddin, Nurhikma; Andriawan, Riki
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15251

Abstract

Aloe vera and senggani leaf can accelerate tissue regeneration, re-epithelialization, fibroblast stimulation, and collagen formation in the skin for burns wound healing. Burns wound can cause damage in the capillaries of the skin, then Aloe vera and senggani leaf were formulated into the gel formula for burns wound healing. The gel has the advantage of high water content; then it will hydrate the epidermis layer, increasing the penetration of the active substances. This study aims to formulate a gel of extract Aloe vera and senggani leaf (Melastoma polyanthum) and to evaluate the burns wound healing activity. The gel was formulated by composition of Aloe vera : senggani leaf with concentrations (0.5%: 1%); (0.5% : 3%); and (0.5% : 5%). Burns wound healing activity was observed by the diameter of the burn wound. The result showed that the gel with a concentration of (0.5%: 5%) gave a significance value of 0.692 (p >0.05) against positive control, then it was the formula that effective for burns wound healing.
Efektivitas Pemberian Edukasi secara Online melalui Media Video dan Leaflet terhadap Tingkat Pengetahuan Pencegahan Covid-19 di Kota Baubau: The Effectiveness of Providing Online Education through Video and Leaflet Media on the Knowledge Level of Covid-19 Prevention at Baubau City Sabarudin; Mahmudah, Rifa’atul; Ruslin; Aba, La; Nggawu, La Ode; Syahbudin; Nirmala, Fifi; Saputri, Atika Indra; Hasyim, Muhammad Syawal
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15253

Abstract

Covid-19 is an infectious disease caused by acute respiratory syndrome coronavirus 2 (severe acute respiratory syndrome coronavirus 2 or SARS CoV-2). As of June 30, 2020, 216 countries in the world have been confirmed to have Covid-19 with a positive number of 10,117,687 and have died 502,278. Southeast Sulawesi in particular has been confirmed as of June 30, 2020, as many as 363 positive cases, 234 recovered, and 6 deaths. Meanwhile, in Baubau, there were 20 positive confirmed cases. Compliance with health protocols is believed to prevent transmission of Covid-19. Increasing knowledge through education is one of the methods used to increase compliance. This study aims to determine the effectiveness of Covid-19 prevention education through video media and online leaflets on the level of public knowledge at Baubau City. This study used a Quasi-Experiment with the approach method of The Non-Randomized Without Control Group Pretest and Posttest Design. The population is all people of Baubau City with an affordable population during the Covid-19 pandemic based on 1,600 Whatsapp group participants with a sample size of 120 people. The sampling technique used a purposive sampling method that met certain criteria. Based on the results of statistical tests with Wilcoxon, the value on the use of video media & leaflets was obtained P = 0.001 <0.05, this indicates that there is a significant difference in knowledge before and after online education. On video media P = 0.248> 0.05 showed that there is no significant difference after online education. Whereas in the media leaflet P = 0.045 <0.05 indicated that there is a significant difference after online education. In this study, video media & leaflets and leaflet media are more effectively used as education on prevention of COVID-19 online compared to video media alone.
Efek Sitotoksik Ekstrak dan Fraksi Umbi Paku Atai Merah (Angiopteris ferox Copel) Terhadap Sel Kanker Payudara T47D: Cytotoxic Effects of Paku Atai Merah (Angiopteris ferox Copel) Tuber Extract and Fractions against T47D Breast Cancer Cells Aisyah, Andi Nur; Nur, Syamsu; Lukitaningsih, Endang; Rumiyati, Rumiyati; Burhan, Asril; Adjara, Syafia Mustika; Rahim, Kurnia
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 6 No. 2 (2020): (October 2020)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2020.v6.i2.15255

Abstract

The use of natural products has been widely used as a resource of new bioactive chemical compounds. One of them is the Paku Atai Merah (Angiopteris ferox Copel) tuber which has long been used empirically by the Dayak tribe of East Kalimantan as an anti-cancer. The purpose of this study was to determine the anticancer cytotoxic activity of the extract and fractions of Paku Atai Merah tuber against T47D breast cancer cells in vitro. Extract of Paku Atai Merah tubers was obtained by maceration method using ethanol solvent until obtained the ethanolic extract then fractionated using various solvents to obtain n-hexane, ethyl acetate, and aqueous-ethanol fractions. The cytotoxic effect was carried out based on the MTT assay. Phytochemical screening tests showed positive results for the presence of flavonoid, phenolic, tannin, saponin and steroid compounds. The results of the cytotoxic activity study showed that the ethyl acetate fraction had moderate cytotoxic activity in T47D cancer cells with an IC50 value of 84.8 µg/ml. Ethanol extract (513.06 µg/ml) and n-Hexane frsction (881.97 µg/ ml) were also included in the weak category. This study indicates that ethyl acetate fraction can be developed as a supportive therapy for breast cancer treatment.
Screening Bioactivity of Kersen Fruits (Muntingia calabura L.) as a Sunscreens Candidate: Skrining Bioaktivitas dari Buah Kersen (Muntingia calabura L.) sebagai Kandidat Bahan Tabir Surya Nur, Syamsu; Nursamsiar, Nursamsiar; Aswad, Muhammad; Tumigolung, Aprilia Ester Eunike; Risfah Yulianti; Burhan, Asril
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15257

Abstract

Kersen (Muntingia calabura L) fruits have the potential to be used as an active ingredient in sunscreens because of phenolic and flavonoid content that can absorb UV rays. This study aims to determine the percentage of erythema/pigmentation transmission and SPF value as parameters for sunscreen activity. Kersen fruits were extracted by maceration using 96% ethanol. The ethanol extract of Kersen Fruits was also fractionated to separate the components of the active compounds based on the polarity level using n-hexane, ethyl acetate, and ethanol as solvents. The test was carried out using the in vitro method by measuring the ability of the material to absorb ultraviolet light at a wavelength of 292.5-372.5 nm. This research was conducted at concentrations of 100, 200, 400, 600, and 800 µg/mL for ethanol, lyophilisate, n-hexane, and ethanol fractions, while the ethyl acetate fraction concentrations are 50, 100, 150, 200, 250 µg/mL. The results showed the best value at the ethyl acetate fraction concentration of 250 µg/mL with % Te of 5.28 and % Tp of 28.65 and the SPF value of 16.54. Based on the % Te and Tp, the ethyl acetate fraction exhibited protection against erythema and pigmentation with the category of extra protection and based on the SPF value with the category of ultra protection.
The Encapsulation Effect on Viability of Mesenchymal Stem Cells: Pengaruh Enkapsulasi Terhadap Viabilitas Sel Punca Mesenkimal Siburian, Marsudi; Sismindari; Rilianawati
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15258

Abstract

Stem cells are potentially used as a regenerative therapy agent. Cell encapsulation is one of the developed methods to utilize Mesenchymal Stem Cells (MSCs) for therapy. This research aimed to study the effect of encapsulation using alginate-CaCl2 towards the viability of hAdMSCs during in vitro culture. Encapsulation of hAdMSCs with alginate-CaCl2 was done using the extrusion method. The viability of hAdMSCs was analyzed with Live/Dead Assay and MTT assay. The results indicated that cultured hAdMSCs within alginate remain alive for 7 days culture period. However, the viability was lower than the reference culture. The absorbances from MTT assay of encapsulated MSCs were lower than the conventional hAdMSCs culture. This result indicated lower metabolic activity of hAdMSCs when cultured in alginate beads.
Review of Impact and Handling of Potential Antihypertensive Drug Interactions in Chronic Kidney Disease Patients: Review Dampak dan Penanganan Potensi Interaksi Obat Golongan Antihipertensi pada Pasien Penyakit Ginjal Kronis Ni Made Susilawati; Eli Halimah; Siti Saidah
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15332

Abstract

Drug interaction is a type of Drug-Related Problems (DRPs) that caneventually increase morbidity and mortality rates. CKD patients have asignificant risk of developing polypharmacy due to comorbid diseases andpharmacokinetics' alteration. The literature review was conducted byexploring all of the articles related to the drug interaction using druginteraction analysis program in CKD patients, which obtained from threedatabases, namely Google Scholar, PubMed, and Science Direct, usingseveral keywords combination. Based on the comprehensive reviewsconducted, it is known that the most common effects of antihypertensivedrug interactions in CKD patients are decreasing effects of antihypertensivedrugs, hypotension, and hyperkalemia. Handling management used for theemergence of potential drug interactions is based on the severity of the druginteractions and complete knowledge of the patients' clinical condition. Themanagement of drug interaction by monitoring blood pressure, diuresis, andpotassium levels; Monitor the related effect symptoms; Monitor the fluidand body weight; Monitor the kidney and heart function. On the conditionwhere the handling management of potential drug interactions is not carriedout, elevated morbidity and mortality rates are the risks of complicationsarising from the drug interactions.
Exploration of Types and Consumption Behaviour of Usada-based Herbal Galactagogue on Lactating Mothers in Bali : Explorasi Jenis dan Perilaku Konsumsi Galaktagogue Herbal berbasis Usada pada Ibu menyusui di Bali Monika, Ni Luh Gde Mona; Yunita, Ella
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 1 (2021): (March 2021)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i1.15342

Abstract

Breastfeeding is essential for the health of newborn infants and mothers. Basic health research in 2018 showed that exclusive breastfeeding in Bali has not reached the national target. High rates of cesarean section delay breastfeeding initiation, the important predictor of continued breastfeeding. Main concern for breastfeeding mothers about medications increased the use of herbal galactagogue to aid lactation. The use of traditional medicinal plant in Bali is 40% higher than national average and its existence is strengthened by the issuance of Bali Governor Regulation No. 55/2019 concerning Traditional Balinese Health Services. Despite increasing popularity of traditional medicine, there are currently limited data available on the plant list and pattern of use herbal galactagogue. This study aims to explore the galactagogue plants, pattern of use, perceived effectiveness of herbal galactagogues during breastfeeding among breastfeeding mother’s in Bali. This study was conducted using a questionnaires and in-depth interviews. The questionnaire and interview guideline were validated by lactation consultants and traditional health practitioners in Bali. The study was approved by Human Research Ethic Committee of Bina Usada Bali. The use of herbal galaktagogue is mostly practiced by highly educated mothers, mother’s occupation as health workers and primiparous. There are 26 types of plants that are often used by lactating mothers in Bali. Majority of respondent begin to use herbal galactagogue after giving birth (82%) for approximately less than 1 month. Majority of lactating mothers in Bali perceived effectiveness of herbal galactagogue usage based on breastfeeding adequacy indicators. About 95% respondents feel confidence and have self-empowerment after using herbal galactagogue, possessing psychological benefits. The use of herbal galactagogue is common amongst breastfeeding mothers in Bali, while information about efficacy and safety is lacking. Further research is needed to give evidence-based information to support exclusive breastfeeding

Page 15 of 25 | Total Record : 247

 13   14   15   16   17 

Filter by Year

2015 2025


Reset
Filter By Issues
All Issue Vol. 11 No. 2 (2025): October 2025 Vol. 11 No. 1 (2025): (March 2025) Vol. 10 No. 2 (2024): (October 2024) Vol. 10 No. 1 (2024): (March 2024) Vol. 9 No. 2 (2023): (October 2023) Vol. 9 No. 1 (2023): (March 2023) Vol. 8 No. 2 (2022): (October 2022) Vol. 8 No. 1 (2022): (March 2022) Vol. 7 No. 3 (2021): (December 2021 Vol. 7 No. 2 (2021): (October 2021) Vol. 7 No. 1 (2021): (March 2021) Vol. 6 No. 2 (2020): (October 2020) Vol. 6 No. 1 (2020): (March 2020) Vol. 5 No. 2 (2019): (October 2019) Vol. 5 No. 1 (2019): (March 2019) Vol. 4 No. 2 (2018): (October 2018) Vol. 4 No. 1 (2018): (March 2018) Vol. 3 No. 2 (2017): (October 2017) Vol. 3 No. 1 (2017): (March 2017) Vol. 2 No. 2 (2016): (October 2016) Vol. 2 No. 1 (2016): (March 2016) Vol. 1 No. 2 (2015): (October 2015) Vol. 1 No. 1 (2015): (March 2015) More Issue