cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Adhar Arifuddin
Contact Email
healthytadulako@gmail.com
Phone
+6285242303103
Journal Mail Official
healthytadulako@gmail.com
Editorial Address
Jl. Soekarno Hatta KM.9, Fakultas Kedokteran Universitas Tadulako , Palu, Provinsi Sulawesi Tengah, 94148
Location
Kota palu,
Sulawesi tengah
INDONESIA
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako)
Published by Universitas Tadulako
ISSN : 24078441     EISSN : 25020749     DOI : https://doi.org/10.22487
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) merupakan media komunikasi dan publikasi ilmiah di bidang ilmu kesehatan yang diterbitkan oleh Unit Penjaminan Mutu Fakultas Kedokteran Universitas Tadulako yang. Jurnal ini terbit secara berkala 4 kali dalam setahun (Januari, April, Juli dan Oktober). Jurnal Tadulako Sehat diterbitkan pertama kali pada tahun 2015. Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) menerima dan menerbitkan artikel penelitian, tinjauan pustaka dan laporan kasus di bidang kedokteran dan kesehatan.
Arjuna Subject : Profesi Kesehatan - Profesi Kesehatan (Lain-Lain)
Articles 393 Documents
 35   36   37   38   39 
Characteristics of Inguinal Hernia Patients at Massenrempulu Hospital for the Period of 2023 S, Fatma Dilla; Gani, Azis Beru; Zulfahmidah, Zulfahmidah; Purnamasari, Reeny; Mubarak, Andi Firman
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1682

Abstract

Background: Hernia is a condition that can occur at all ages, characterized by a lump that appears and disappears. Inguinal hernia is the most common type, with lateral inguinal hernia accounting for 50%, medial 25%, and femoral 15%. About 15% of adults suffer from inguinal hernia, with prevalence increasing from 5–8% at ages 25–40 years to 45% at age 75. Hernia repair remains the most effective general surgical procedure. Objective: To determine the characteristics of inguinal hernia patients at Massenrempulu Hospital in 2023 based on age, occupation, classification, and body mass index (BMI). Methods: This study used a descriptive method with an observational design. Data were analyzed by frequency distribution according to research variables. Results: Inguinal hernia was more common in patients aged >66 years (45.9%), in heavy work occupations (70.3%), and classified predominantly as indirect/lateral inguinal hernia (94.6%). Based on BMI, most patients were in the overweight category (54.1%). Conclusion: At Massenrempulu Hospital in 2023, inguinal hernia was mostly found in patients aged >66 years, engaged in heavy work, with indirect/lateral classification, and overweight BMI
Characteristics of Thyroid Eye Disease Patients at Wahidin Sudirohusodo Hospital Makassar Jayanti, Usna; Kusumawardhani, Sri Irmandha; Lantara, Andi Millaty Halifah Dirgahayu; Maharani, Ratih Natasha; Namirah, Hanna Aulia
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1704

Abstract

Background: Thyroid Eye Disease (TED) is an autoimmune orbital disorder frequently associated with Graves’ disease, marked by orbital fat expansion and extraocular muscle swelling that may impair vision and quality of life. Objective: To describe the characteristics of TED patients at RSUP Wahidin Sudirohusodo Makassar based on age, gender, clinical manifestations, management, and smoking history. Methods: A descriptive study of 55 TED patients recorded at RSUP Wahidin Sudirohusodo Makassar. Results: Most patients were aged 20–44 years (60%), followed by 45–64 years (34.55%) and 13–19 years (5.45%), with no cases above 65 years. Females predominated (61.82%). The most common symptom was proptosis (100%), followed by excessive tearing (49.09%), red eyes (27.27%), refractive errors (23.64%), diplopia (10.91%), pain during eye movement (7.27%), and photophobia (7.27%). The main treatment was intravenous methylprednisolone plus thiamazole (47.27%), followed by intravenous methylprednisolone alone (18.18%), thyrozol (18.18%), and propranolol (9.09%). One patient (1.82%) underwent orbital decompression. Active smoking was reported in 32.73% of patients. Conclusion: TED patients were predominantly females aged 20–44 years, with proptosis as the leading manifestation. The most common management was intravenous methylprednisolone combined with thiamazole. Smoking may worsen disease severity
Comparison of Antibacterial Activity Tests of 70% and 96% Ethanol Extract on Siam Sambas Orange Leaves (Citrus nobilis var. microcarpa) Zakiah, Mistika; Asseggaf, Syarifah Nurul Yanti Rizki Syahab; Ulfah, Ridha; Putri, Triyana Harlia; Hendrayana, Bimo; Putra, Galih Abisatya Hartono
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1705

Abstract

Background: Antibiotic resistance against bacterial infections such as Escherichia coli and Staphylococcus aureus, prevalent in tropical regions, necessitates alternative treatments. One potential solution is utilizing secondary metabolites found in Sambas Siamese orange leaves. These compounds may serve as antibacterial agents. Objective: This study aims to compare the effectiveness of 70% and 96% ethanol as solvents for extracting secondary metabolites from Sambas Siamese orange leaves. Methods: Extraction was performed using two types of solvents (70% and 96% ethanol) to obtain secondary metabolites. Antibacterial activity was tested using the disc diffusion method (Kirby-Bauer), and data were analyzed with One-Way Analysis of Variance (ANOVA). Results: Extraction with 96% ethanol yielded flavonoids (+++), terpenoids (++), steroids (++), and phenols (++). Meanwhile, extraction with 70% ethanol produced Mayer alkaloids (++), flavonoids (++), saponins (+), steroids (+++), and phenols (+++). The 96% ethanol solvent was more effective in extracting limonene compounds from the leaves. Conclusion: The 96% ethanol solvent demonstrated higher effectiveness compared to 70% ethanol in extracting secondary metabolites, particularly limonene, which has potential antibacterial properties, from Sambas Siamese orange leaves
Characteristics of Hypertension Patients at Lanto Dg Pasewang Jeneponto Regional General Hospital 2022-2023 Saputra, Muh Farhan; Royani, Ida; Hamzah, Pratiwi Nasir; Harahap, Muhammad Wirawan; Tahir, Akina Maulidhany
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1718

Abstract

Background: Cardiovascular diseases, including hypertension (blood pressure >/140/90 mmHg), contribute to heart and vascular damage. Risk factors include non-modifiable factors (age, gender, family history) and modifiable factors (smoking, behavior, alcohol). Objective: This study aimed to identify the characteristics and risk factors of hypertensive patients at RSUD Lanto DG Pasewang Jeneponto. Methods: A descriptive study using secondary data from medical records of hypertensive patients at RSUD Lanto DG Pasewang Jeneponto was conducted in September 2024. Data were analyzed descriptively by age, gender, hypertension grade, body mass index (BMI), and comorbidities. Results: A total of 93 patients were included. Most patients were aged 61–70 years (31.2%), followed by 51–60 years (26.9%). Females (59.1%) were more affected than males (40.9%). The majority (92.5%) had grade 2 hypertension. Based on BMI, 63.4% were normal, 21.5% overweight, and the rest underweight, obese, or grade 2 obese. Comorbidities included heart disease (76.3%), diabetes (14%), and kidney failure (9.7%). Conclusion: Most hypertensive patients at RSUD Lanto DG Pasewang Jeneponto were aged 60–70 years, female, had normal nutritional status, grade 2 hypertension, and a history of heart disease.
Risk Factors for the Incidence of Cholelithiasis at Ibnu Sina Makassar Hospital for the 2021-2023 Period Yusuf, Awalia Rezeki S; Bamahry, Aryanti R; Yanti, Andi Kartini Eka; Gani, Aziz Beru; Kanang, Indah Lestari Daeng
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1721

Abstract

Background: Cholelithiasis is an important health problem with severity and septic complications related to the type of gallstone. Several risk factors also influence the incidence of cholelithiasis. Objective: This study aims to determine the distribution of cholelithiasis patients based on gender, Body Mass Index (BMI), age, childbearing age in women, triglyceride levels, and total cholesterol levels at Ibnu Sina Hospital Makassar in the period 2021 to 2023. Method: This type of research is descriptive using a Cross Sectional Study approach, namely explaining the risk factors for the incidence of cholelithiasis at Ibnu Sina Hospital Makassar. Results: The distribution of cholelithiasis patients at Ibnu Sina Hospital Makassar in 2021-2023 shows that the risk factors are mostly female, overweight/obesity, age >40 years, hypertriglyceridemia, and hypercholesterolemia. However, women of childbearing age suffer less from cholelithiasis than older women. Conclusion: Cholelithiasis at Ibnu Sina Hospital Makassar in 2021-2023 is more common in women, >40 years of age, overweight/obesity, hypertriglyceridemia, and hypercholesterolemia, with a lower incidence in women of childbearing age compared to old age.
Literature Review: The Effect of Extra Virgin Olive Oil (Olea europaea L.) on Pseudomonas aeruginosa Bacteria Domu, Anugrah Julistiar Aksan; Syamsu, Rachmat Faisal; Karim, Marzelina; Hadi, Santriani; Arfah, Arni Isnaini
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1722

Abstract

Background: Olive oil, especially Extra Virgin Olive Oil (EVOO), which contains polyphenols and phytochemical compounds such as flavonoids and oleuropein, has long been utilized to enhance human health and exhibits potential antibacterial activity against Pseudomonas aeruginosa, an opportunistic pathogenic bacterium often responsible for severe infections and resistance to various antibiotics. Objective: To investigate the antibacterial properties of extra virgin olive oil (Olea europaea L.) against Pseudomonas aeruginosa. Method: A literature review study obtained from the internet, including theses, journals, textbooks, and e-books. The databases used were Google Scholar, Elsevier, ScienceDirect, and PubMed NCBI. Results: Extra Virgin Olive Oil (EVOO) demonstrates antibacterial activity against Pseudomonas aeruginosa based on findings from 10 journals. Bioactive compounds such as polyphenols, oleuropein, and hydroxytyrosol are effective against Pseudomonas aeruginosa through mechanisms that include inhibiting quorum sensing, damaging the cell wall, increasing membrane permeability, and inhibiting biofilm formation and virulence factors. Olive leaf extract and combinations with nanoparticles further enhance antibacterial effectiveness against resistant strains, making EVOO a potential natural antibacterial agent. Conclusion: Olive oil, particularly Extra Virgin Olive Oil (EVOO), contains bioactive compounds such as oleacein, oleocanthal, polyphenols, flavonoids, oleuropein, and hydroxytyrosol, which exhibit significant antibacterial activity against Pseudomonas aeruginosa.
PD-1 and PDL-1 Immune Checkpoint Inhibitors: Emerging Hope for the Future of Lung Cancer Immunotherapy Ilyasa, Muhammad Riza; Ramadhani, Muhammad Zulmi; Santoso, Rex Jeremy; Hutasoit, Gina Andyka; Miskad, Upik Anderiani
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1723

Abstract

Background: Lung cancer is the leading cause of cancer-related deaths worldwide, with Non-Small Cell Lung Cancer (NSCLC) being the most common type. Despite advances in treatment, the prognosis remains poor. Immune checkpoint inhibitors targeting PD-1 and PD-L1 have emerged as a promising first-line treatment approach in combating cancer. Objectives: This literature review aims to evaluate the effectiveness of PD-1 and PD-L1 immune checkpoint inhibitors in the treatment of NSCLC. It also explores the potential of these inhibitors to improve patient survival rates compared to conventional therapies. Methods: A systematic literature search was conducted using databases such as PubMed, Google Scholar, ScienceDirect, and NCBI, with keywords including "PD-1," "PD-L1," "NSCLC," "lung cancer," and "immunotherapy." Results: All four inhibitors significantly improve survival rates compared to traditional chemotherapy. Atezolizumab and pembrolizumab show high effectiveness in patients with high PD-L1 expression. Durvalumab, when combined with chemotherapy, overcomes resistance mechanisms. Nivolumab, enhancing survival rates. Conclusion: PD-1 and PD-L1 inhibitors provide substantial benefits in the treatment of NSCLC, including increased survival rates and reduced need for aggressive therapies. Further research should focus on optimizing combination therapies to expand the therapeutic benefits of these inhibitors.
Description of Appendicitis Patients Post-Appendectomy at Prof. Dr. H. Aloei Saboe Hospital Gorontalo in 2023 Aryaputra, fadhil; Abdul, Romy; Antu, Yuniarty; Siregar, Muchtar Nora Ismail; Kasim, Vivien Novarina A
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1731

Abstract

Background: Appendicitis is an acute or chronic inflammation of the appendix caused by obstruction of the lumen. According to the World Health Organization (WHO), appendicitis ranked eighth as a global cause of death in 2014. Objective: To describe the characteristics of post-appendectomy appendicitis patients at Aloei Saboe Hospital, Gorontalo, in 2023. Methods: A retrospective descriptive study was conducted in June–August 2024 at Aloei Saboe Hospital, Gorontalo. The population included appendicitis patients who underwent appendectomy between January–December 2023. Using purposive sampling, 98 patient medical records were analyzed. Data were described based on gender, age, and surgical procedure. Results: Most patients were female (64.3%). The highest age distribution was late adolescence (17–25 years) at 39.8%. The most frequent surgical technique performed was open appendectomy (53.1%), followed by other procedures. Conclusion: At Aloei Saboe Hospital, the majority of post-appendectomy appendicitis patients were female, predominantly in late adolescence, with open appendectomy being the most common surgical method. These findings are expected to provide useful information and education for individuals with high-risk factors for appendicitis.
Different Sepsis Patient Outcomes Due to Multidrug-Resistant Organisms (MDRO): A Study of Empirical Antibiotic Sensitivity Test Results Fadrian, Fadrian; Ahmad, Armen; Harvindra, Astrid; Putri, Vidola Yasena
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1740

Abstract

Background: Sepsis, a severe immune response to infection, has a concerning global mortality rate of 85%, predominantly due to Gram-negative bacteria. The rise of antibiotic resistance in these organisms complicates treatment, leading to higher mortality and prolonged hospital stays. Effective empirical antibiotics can mitigate these outcomes. Objective: This study compares outcomes of sepsis patients infected with multidrug-resistant organisms (MDRO) based on empirical antibiotic sensitivity testing, focusing on mortality and length of stay (LOS) within 14 days of sepsis onset. Methods: A prospective cohort observational study at Dr. M. Djamil General Hospital included 94 participants. Patients who died within 14 days were excluded from the LOS analysis to prevent bias. Initial assessments included culture sampling and organ dysfunction. Results: The study revealed no significant difference in mortality based on antibiotic sensitivity (p=0.283), but the LOS was significantly shorter in those treated with sensitive antibiotics (p<0.016). Conclusion: LOS was significantly affected by antibiotic sensitivity, with patients receiving effective antibiotics experiencing shorter stays, though mortality differences were not statistically significant in the 14-day window
Characteristics of Osteoarthritis Genu Patients at Ibnu Sina Hospital Makassar Based on Clinical Manifestations, Body Mass Index, and Radiological Imaging Aisyah, A Aidha Nurul; Nurmadilla, Nesyana; Syahruddin, Febie Irsandy; Putra, Fadil Mula; Rahmawati, Rahmawati
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1748

Abstract

Background: Knee osteoarthritis is a major cause of chronic pain and disability in the elderly. Obesity is a key risk factor, as excess body weight increases pressure on knee joints. Clinical and radiological assessments are essential to determine disease severity. Objective: To describe the characteristics of knee osteoarthritis patients at Ibnu Sina Hospital Makassar during 2023–2024 based on clinical manifestations, body mass index (BMI), and radiological imaging. Methods: A descriptive cross-sectional study was conducted using medical records of 63 patients with knee osteoarthritis. Variables analyzed included clinical manifestations, BMI, and radiological grading. Results: Of 63 patients, most (50.8%) presented with bilateral knee pain as the main complaint, while 25.4% experienced knee swelling. BMI analysis showed that the largest proportion of patients were in obesity class I (30.2%). Radiological imaging revealed that 41.3% were classified as grade II according to the Kellgren and Lawrence criteria. Conclusion: Knee osteoarthritis patients at Ibnu Sina Hospital Makassar were predominantly characterized by bilateral knee pain, obesity class I, and grade II radiological severity. Interventions such as weight management, physiotherapy, and public education on joint health are important to reduce risk and slow disease progression

Page 37 of 40 | Total Record : 393

 35   36   37   38   39 

Filter by Year

2015 2025


Reset
Filter By Issues
All Issue Vol. 11 No. 4 (2025) Vol. 11 No. 3 (2025) Vol. 11 No. 2 (2025) Vol. 11 No. 1 (2025) Vol. 10 No. 4 (2024) Vol. 10 No. 3 (2024) Vol. 10 No. 2 (2024) Vol. 10 No. 1 (2024) Vol. 9 No. 3 (2023) Vol. 9 No. 2 (2023) Vol. 9 No. 1 (2023) Vol. 8 No. 3 (2022) Vol. 8 No. 2 (2022) Vol. 8 No. 1 (2022) Vol. 7 No. 3 (2021) Vol. 7 No. 2 (2021) Vol. 7 No. 1 (2021) Vol. 6 No. 3 (2020) Vol. 6 No. 2 (2020) Vol. 6 No. 1 (2020) Vol. 5 No. 3 (2019) Vol. 5 No. 2 (2019) Vol. 5 No. 1 (2019) Vol. 4 No. 3 (2018) Vol. 4 No. 2 (2018) Vol. 4 No. 1 (2018) Vol. 3 No. 2 (2017) Vol. 3 No. 1 (2017) Vol. 2 No. 2 (2016) Vol. 2 No. 1 (2016) Vol. 1 No. 2 (2015) Vol. 1 No. 1 (2015) More Issue