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Majalah Kedokteran Gigi Indonesia
ISSN : 24600164     EISSN : 24422576     DOI : https://doi.org/10.22146/majkedgiind.36959
Core Subject : Health,
Arjuna Subject : -
Articles 575 Documents
Antimicrobial photodynamic therapy with erythrosine photosensitizer against immune response in chronic periodontitis model Rochmawati, Mutia; Kusuma, Maulidina Raihan; Maziyyah, Faiz; Naim, Cantika Nadrotan; Prihastuti, Christiana Cahyani; Satrio, Rinawati; Laksitasari, Anindita; Sari, Dwi Nur Indah; Ichsyani, Meylida
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.77084

Abstract

Chronic periodontitis is a progressive inflammatory disease of the supporting tissues of the teeth caused by dental plaque bacteria with a clinical sign of periodontal pockets. A Gram-negative bacterium that can trigger this inflammatory disease is Porphyromonas gingivalis. Antimicrobial photodynamic therapy with blue LED light irradiation and photosensitizer erythrosine can reduce the survival rate of P. gingivalis. This study aimed to determine the effects of antimicrobial photodynamic therapy (APDT) exposure with blue LED light irradiation and PS erythrosine on the number of macrophages, lymphocytes, and gingival fibroblasts in gingival tissue of Sprague Dawley rats as chronic periodontitis models. This study used a posttest-only control group design to examine 27 Sprague Dawley rats which were divided into P group (healthy rats), N group (untreated chronic periodontitis rats), and PDT groups (chronic periodontitis model given 1 mg/ml PS erythrosine and irradiated with blue LED light for 60 seconds). Cell observation of histologic preparations of rat gingival tissue with hematoxylin-eosin (H&E) staining was carried out on the 1st, 3rd, and 5th days. Histological preparations of gingival tissue with H&E staining was carried out on the 1st, 3rd, and 5th days. Statistical analysis used a one-way ANOVA and the Kruskal-Wallis test, continued with LSD and the Mann-Whitney post-hoc tests. Results showed significant difference in the mean of macrophages in the PDT group compared to the untreated chronic periodontitis group on the 1st, 3rd, and 5th days (p < 0.05). The mean lymphocyte in the PDT group was significantly different from the untreated chronic periodontitis group on the 1st, 3rd, and 5th days (p < 0.05), and significantly lower than that in the healthy group (p < 0.05) but only on the 3rd and 5th days. The mean fibroblast in the PDT group was significantly different compared to the untreated chronic periodontitis group on the 1st, 3rd, and 5th days (p < 0.05). In conclusion, there were significant differences in the number of macrophages, lymphocytes, and fibroblasts in a chronic periodontitis rat model after treatment with APDT exposure with blue LED and erythrosine photosensitizer.
Effectiveness of vitamin D3 supplementation with protein realimentation in osteoblast and osteoclast of the maxilla of breastfed malnourished rat infants Hidayah, Riski Amalia; Kurniawan, Aris Aji; Widyaningsih, Pratiwi Nur; Rakhmawati, Rakhmawati
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.78293

Abstract

Child malnutrition can happen because of lack of nutrition during pregnancy. Malnutrition can cause low birth weight in babies. This can cause jaw and alveolar bone abnormalities that can lead to malocclusion, periodontitis, and others. This condition can affect bone cells, such as osteoblast and osteoclast. Vitamin D3 supplementation accompanied by protein realimentation may promote optimum bone growth. This research aims to investigate the effect of protein realimentation and vitamin D3 on osteoblast and osteoclast of malnourished rat pups’ maxilla. In this research, the rat pups were divided into 5 groups: a positive control group (K+), a negative control group (K-), and 3 treatment groups (P1, P2, and P3). The subjects of this research were 10 male and 30 female Wistar rats. A condition of malnutrition was induced in the rat pups and they were given vitamin D3 supplementation with protein realimentation. Rat pups in each group were euthanized on the 22nd day to observe the number of osteoclast and osteoblast in the maxilla. The results showed that the number of osteoblasts between normal and malnourished rats was significantly different (p value < 0.05), but the number of osteoclasts between rats in the control and treatment groups was not significantly different. Administration of vitamin D3 may affect the number of osteoblasts and may not affect the number of osteoclasts on bone. The effective dose of vitamin D3 is 0.36 IU/day.
Association between childhood obesity, oral health behavior, and dental caries in Jetis, Yogyakarta Narta Sari, Nikita; Hanindriyo, Lisdrianto; Priyono, Bambang
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.79240

Abstract

The number of school-age children with overweight and obesity is increasing in developing countries. This is a risk factor for prosperity improvement followed by lifestyle changes. People with obesity are reported to be more susceptible to caries than people who are not, and the average numbers of caries in permanent molars increase on higher BMI. Dental caries is an infectious disease as a result of demineralization in enamel and dentine which has a relationship with behavior. The purpose of this study was to determine the relationship between oral health behavior and dental caries among overweight and obese children in Jetis District, Yogyakarta. This research was an analytical observational study with a cross sectional design. One hundred and ninety-six overweight and obese elementary school children in Jetis District were chosen using multistage cluster random sampling. The independent variable was behavior and the dependent variable was dental caries. Behavior variables were measured using questionnaire based on a Likert scale with validity testing (correlation coefficient > 0.30) and reliability testing (Cronbach alpha = 0.819). The caries was measured using teledentisry during the COVID-19 pandemic. Data analysis used Spearman’s correlation analysis. Behavior of maintaining oral and dental health in overweight and obese children had a relationship with caries (p < 0.001 and r = -0.410). There is no difference between overweight and obese children in maintaining their oral health behavior. The better the oral health behavior of the overweight and obese children, the lower the incidence of caries.
Management of herpangina: a viral infection in infants Prathiwi, Caecilia Dewi Ratna; Bramanti, Indra
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.79883

Abstract

Herpangina is a self-limiting disease caused by coxsackievirus. The manifestation consists of acute febrile with small ulcerative or vesicular lesions on the tonsillar, soft palate, uvula and buccal mucosa. The disease mostly affects children. The aim of this case report is to discuss the oral symptoms of herpangina based on current literature for dental and health practitioners. In our case, a 15-month-old baby girl presented with high fever reaching 40.2 °C for 2 days with no seizures, cold and cough. Intra oral examination showed several well-defined whitish round lesions on the soft palate and one on the upper left lip. The patient was prescribed 3ml of methisoprinol 250 mg 3 times a day, 4 ml of paracetamol 125 mg every 6 hours, hyaluronic acid spray 3 times a day, and 1ml of vitamin C 40 mg taken once a day. The patient showed no sign of bacterial infection. Lesion disappeared after 7 days of treatment. Upon follow-up visit after 2 weeks, the lesion had completely disappeared. Dentists should be able to recognize and manage herpangina cases in infants.
Radiographic analysis of teeth calcification of breastfed rat cubs of mothers consuming excessive Arabica coffee Apriyono, Dwi Kartika; Shita, Amandia Dewi Permana; Fatimatuzzahro, Nadie; Prasetya, Rendra Chriestedy; Umaimah, Ulfa
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.80243

Abstract

Lack of nutrient intake, especially calcium, can inhibit tooth development because calcium is the major component of the inorganic material that forms enamel and dentin. Caffeine in coffee can decrease calcium levels in the body. Arabica coffee has a very high caffeine content compared to other types of coffee. Excessive caffeine consumption can cause the inhibition of PTH secretion. As a result, the nursing mother's body cannot absorb calcium optimally. This makes the baby lack calcium intake which is used for the dental calcification process. This study analyzes radiographic images of tooth calcification of rat cubs during lactation period from rat mothers which consumed excess doses of Arabica coffee. Forty-eight breastfeeding rat mothers (n = 48) were divided into a control group and a treatment group. The control group consisted of 24 rat mothers that were given aquadest. The treatment group consisted of 24 nursing rat mothers, which were given coffee orally at a dose of 2.7 grams/200 grams/day. After the rat mothers gave birth (H + 1 to H + 18), every 4 rat cubs were euthanized, then the mandibular bones were X-rayed. Dental calcification was viewed and analyzed based on radiographic images. The teeth of rat cubs whose mothers consumed excess doses of Arabica coffee experienced a delay in the calcification stage compared to the teeth of normal rat cubs. Consumption of Arabica coffee by nursing mothers can cause a delay in the stage of dental calcification in rat cubs.
Development of dentists perceptions and knowledge of teledentistry Boanjoy, Sarah Margareth; Setiawan, Asty Samiaty; Suryanti, Netty
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.80994

Abstract

Teledentistry is a dental health service that provides consultation, guidance, or education remotely using information technology. Perception and knowledge play an essential role in the implementation of teledentistry. The purpose of this study was to explore the development of dentists' perceptions and knowledge of the concept of teledentistry. This study used a scoping review method based on the Joanna Briggs Institute methodology. Screening and study selection were carried out using the Preferred Reporting Items of Systematic Reviews and Meta-Analysis Scoping Reviews (PRISMA-Scr). Literature searches were conducted through PubMed, Science Direct, and EBSCOHost with keywords and inclusion criteria, hand searching, and viewing the list of selected article references. There were 23 articles analyzed according to the inclusion and exclusion criteria. Changes in dentists' perceptions of teledentistry would help shorten waiting list, reduce costs for dental practice, additional visits to take photographs, and additional costs to provide facilities/ equipment for teledentistry before and during the COVID-19 pandemic. Three articles (2015-2016) state that most dentists did not know or have little knowledge about teledentistry. Nine articles published during the pandemic revealed that the majority of dentists had knowledge of teledentistry. The results of this study found that developments in dentists’ perception, namely teledentistry would help shorten waiting list, reduce costs for dental practice, the need for additional visits to take photographs, and additional costs to provide facilities/ equipment for teledentistry. The level of knowledge of dentists about teledentistry increased during the COVID-19 pandemic.
Risk factors for dental caries in adults aged 35-44 years in DKI Jakarta: a cross-sectional study using the 2018 national Riskesdas data Kristanto, Cindy Vania; Theresia, Tiarma Talenta
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.81549

Abstract

Caries, an oral cavity disease with several causes, is significantly increasing. According to the 2018 Basic Health Research, 92.2% of adults between the ages of 35 and 44 had dental caries. In DKI Jakarta, the prevalence of oral health issues reached a percentage of 59.1%. The purpose of this study was to determine the risk factors for dental caries in adults aged 35-44 years in DKI Jakarta. This research is descriptive observational research with a cross-sectional design. This research uses secondary data from the 2018 Riskesdas. The final total of the respondents was 1,100 after considering the inclusion and exclusion criteria. Based on the results of the research, respondents who were at higher risk of caries development were female (52.2%), employed (68.3%), and had intermediate education (46.3%). Based on certain habits, groups of risk factors that have a high frequency are incorrect time to brush teeth (97.2%), consuming sweet food 1-6x per week (48.5%), consuming sweet drinks ≥ 1x per day (64.3%), consuming soft drinks (89.6%) and energy drinks (93.9%) ≤ 3x per month, not consuming alcoholic beverages (96.8%), and smoking (51.9%). Overall, the prevalence of caries in adults aged 35-44 years in DKI Jakarta is 45%, with a high frequency of various risk factors. Risk factors that are related to the incidence of dental caries are intermediate level of education (OR = 1.19573), high level of education (OR = 1.58056), unemployed (OR = 0.78646), consumption of sweet foods ≥ 1x per day (OR = 0.71107), and smoking (OR = 0.72334).
Evaluation of viscosity and pH of Zingiber officinale var. officinale juice in mouthwash formulation Stefani, Rosita; Vanessa, Gisela Ellenia; Fibryanto, Eko
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.82071

Abstract

Zingiber officinale var. officinale juice has many benefits, including as a mixture of mouthwash. This research aims to analyze the differences in pH and viscosity values of Zingiber officinale var. officinale-containing mouthwashes with concentrations of 3.125%, 6.25%, and 12.5% on days 0, 14, 28, 42, and 56. Zingiber officinale var. officinale-containing mouthwashes with concentrations of 3.125%, 6.25%, and 12.5% were mixed with propylene glycol, PEG-40 hydrogenated castor oil, oleum menthae, benzoic acid, sodium benzoate, calcium lactate, sorbitol 70% and calcium thiocyanate. The formulation was measured with a pH meter (Jenway, United Kingdom) and a viscometer (Brookfield, Massachusetts) for 56 days. pH data was analyzed using GLM repeated measures ANOVA and one-way ANOVA (p < 0.05). Viscosity data was analyzed using GLM repeated measured ANOVA and the Kruskal-Wallis test (p < 0.05). The pH value of the 3.125% formulation showed significant difference for 56 days in the range of 5.50-5.61. The viscosity value showed no significant difference for 56 days in the range of 3.03-3.09 cP. The pH and viscosity value of the 6.25% formulation showed no significant difference for 56 days with pHs of 5.78-5.83, while the viscosity is 3.12-3.13 cP. The pH and viscosity value of the 12.5% formulation showed no significant difference for 56 days with pHs of 4.90, while the viscosity was 3.43-3.50 cP. The Zingiber officinale var. Officinale mouthwash formulation with a concentration of 3.125% was unstable, but it had the lowest viscosity value and was stable for 56 days. The pH and viscosity value of the 6.25% and 12.5% formulations were stable for 56 days. The highest pH value was in the 6.25% formulation.
Differences in levels of bone morphogenetic protein-2 in periodontitis patients with and without type 2 diabetes mellitus Pritama, Muhammad Fauzi Adityawan; Syaify, Ahmad; Suryono, Suryono
Majalah Kedokteran Gigi Indonesia Vol 9, No 2 (2023): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.83286

Abstract

Periodontitis is characterized by gingival bleeding, periodontal pocket formation, damage to the connective tissue attachment, and alveolar bone resorption. One of the risk factors that can increase the occurrence of periodontitis is diabetes mellitus (DM). In Indonesia, the incidence and prevalence of periodontitis are higher in patients with type 2 DM. In the present study, BMP-2 expression in periodontitis patients with and without type 2 DM was evaluated. We performed a descriptive analytical cross-sectional study in 40 respondents with stages II-III grades B-C chronic periodontitis. They were divided into a chronic periodontitis group with type 2 DM and a chronic periodontitis group without DM. Crevicular fluid of the gingival sulcus of the central maxillary anterior teeth from each respondent was taken using paper points for 5 minutes and placed in an Eppendorf tube. Each tube was labelled according to its group. All of the samples were examined by BMP-2 ELISA kit and measured by BioRad microplate reader with a wavelength of 450 nm. Data were analysed using SPSS 16.0 program. The independent sample t-test was used to compare the BMP-2 among two groups. The results of the study revealed the BMP-2 level in periodontitis patients with type 2 DM was 63.1 pg/ml, while in periodontitis patients without DM was 66.8 pg/ml. BMP-2 levels in periodontitis patients with type 2 DM were significantly lower than those in periodontitis patients without DM (p < 0.05).
Relationship between dental caries level and quality of life of communities aged 35-44 years in South Daha District, South Hulu Sungai Regency Fatma, Sonya; Hamdani, Riky; Purwaningayu, Juli Harnida
Majalah Kedokteran Gigi Indonesia Vol 9, No 3 (2023): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.77301

Abstract

Dental caries is the most common dental and oral health problem worldwide, including in Indonesia. Dental caries can be caused by a person’s decreased level of productivity, and severe dental caries can cause pain and difficulty eating and sleeping, thus affecting the quality of life. This study aims to determine the relationship between the level of dental caries and the quality of life of people aged 35-44 years in Daha Selatan District, Hulu Sungai Selatan Regency, South Kalimantan Province. This research used analytic observational method with a cross sectional approach. The population of this research was 106 people of South Daha District aged 35-44 years who were selected using simple random sampling technique. The results of statistical analysis using the Chi-square test obtained a significance value of 0.012 (p < 0.05), indicating a significant correlation between the level of dental caries and the quality of life of 35-44-year-olds. There is a definite need for increasing public awareness of the importance of maintaining oral and dental health to reduce cases of tooth decay caused by dental caries and improve people’squality of life.