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All Journal MPI (Media Pharmaceutica Indonesiana) Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Journal of Islamic Pharmacy Jurnal Farmasi Indonesia Borneo Journal Of Pharmascientech Bioscientist : Jurnal Ilmiah Biologi Jurnal Farmasi dan Sains Indonesia (JFSI) JOURNAL OF COMMUNITY ENGAGEMENT AND EMPOWERMENT Jurnal EduHealth Jurnal Farmasi Sains dan Praktis Jurnal Ilmiah Sains Jurnal Ilmiah Kesehatan Jurnal Ilmiah Farmasi Simplisia Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat International Journal of Global Sustainable Research Jurnal Pharma Bhakta
Rosa Juwita Hesturini
Institut Ilmu Kesehatan Bhakti Wiyata Kediri
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Jurnal EduHealth

 1 
Activity Test Of Ethanol Extract Of Green Sugarcane Stem (Saccharum Officinarum Linn) As Antidiabetic In Male Mice Prihardini Prihardini; Dewy Resty Basuki; Rosa Juwita Hesturini
Jurnal EduHealth Vol. 14 No. 02 (2023): Periode April-June, 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.937 KB)

Abstract

Diabetes Mellitus is a metabolic disorder characterized by an increase in blood sugar levels caused by the body's inability to produce insulin. One of the non-pharmacological therapies is by utilizing herbal plants such as green sugarcane stalks (Saccarum officinarum L.). Research objective: to find out whether administration of green sugarcane stem extract can reduce alloxan-induced blood glucose levels in mice. Research method: experimental using male males as test animals totaling 25 animals which were divided into 5 groups, namely the negative control group, positive control, a sample group of 100 mg/kg, 125 mg/kg, and 250 mg/kg. Data were analyzed by one-way ANOVA test and continued with the LSD test. The results of the study at a dose of 125 mg/kg BW optimally reduce blood glucose level.
Ethnopharmacology Study Of Medicinal Plants Used By Batak Community In Pasaribu Tobing Sub-District Of Tapanuli Tengah District Of North Sumatra Province Dewy Resty Basuki; Prihardini Prihardini; Rosa Juwita Hesturini
Jurnal EduHealth Vol. 14 No. 03 (2023): Jurnal EduHealt, Edition September 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/jurnaleduhealth.v14i3.2554

Abstract

Ethnopharmacology is an effort to explore and discover new compounds in natural products that are related to the use of traditional medicines that apply to certain ethnic groups. These study has been conducted of ethnoparmacology medicinal plants that utilized the Batak community in Pasaribu Sub District Tobing District Central Tapanuli North Sumatra Province. Methods of this study include observational studies and ethnopharmacology studies. The results showed that the plants that are used as medicine in Pasaribu Tobing Subdistrict include 36 tribes consisting of 61 species, with the most commonly used tribe is Zingiberaceae of 9.83%. The most popular medicinal plants are used as antiseptics. The leaves are part of the most stout plants in use by 41.79%. The treatment of medicinal plants is mostly done by boiling 33.33% and the use of medicinal plants are the most widely used by drinking method by 56.61%.
Antihyperlipidemic Activity of Trembesi Leaf Extract (Samanea saman) Against Total and LDL Cholesterol Levels in Hypercholesterolemic Mice Rosa Juwita Hesturini
Jurnal EduHealth Vol. 14 No. 03 (2023): Jurnal EduHealt, Edition September 2023
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54209/jurnaleduhealth.v14i3.2653

Abstract

The potential of the trembesi plant (Samanea saman) which is used for traditional medicine includes antibacterial, analgesic, treating headaches and diarrhea [1]. Trembesi leaves are known to have several chemical compounds such as flavonoids, alkaloids, tannins, saponins, and steroids or triterpenoids which are thought to have activity in reducing total cholesterol levels [2]. The aim of this study was to determine the activity and optimal dose of trembesi leaf extract which can reduce total and LDL cholesterol levels in hypercholesterolemic mice. Research method: 25 test mice were divided into 5 groups consisting of group 1 given CMC-NA 1% negative control, group 2 given simvastatin 10 mg positive control, groups 3, 4 and 5 were given extract treatment trembesi leaves with doses of 35 mg/KgBW, 175 mg/KgBW and 350 mg/KgBW. The mice tested were given atherogenic feed and then examined for total and LDL cholesterol levels using the CHOD PAP enzymatic method. Data analysis used the one-way ANOVA test, followed by the post hoc test, namely Duncan's test. Results: Ethanol extract of trembesi leaves at a dose of 175 mg/KgBW can reduce total cholesterol levels by 37.07% and LDL by 50.24%. Conclusion: ethanol extract of trembesi leaves at a dose of 175 mg/KgBW provides an optimal effect on reducing total and LDL cholesterol levels (p<0.05).
Co-Authors Ade Giriayu Anjani Adellia Ayu Febriana Afdyta Doria Bilhis Anis Akhwan Dhafin Annisa Diyan Meitasari Briandini Dwi Astuti Dewi Venda Erlina Dewy Resty Basuki Dewy Resty Basuki Dewy Resty Basuki Dewy Resty Basuki, Dewy Resty Dwi Wahyuni Dyah Aryantini, Dyah Elsa Mahardika Putri Erlina, Dewi Venda Faisal Akhmal Muslikh Faisal Akhmal Muslikh Farida Noor Fathul Hidayatul Hasanah, Fathul Hidayatul Fendy Prasetyawan Fenita Shoviantari, Fenita Feny Oktaviana Fita Sari Fita Sari, Fita Gunawan Pamudji Widodo Hardini, Pri Hari Untarto Swandono Hayati, Rachma Nur Hidayatul, Fathul Imanda'ar, Pavitra Meilina Infika Indriana Ira Oktavia KRISNA KHARISMA PERTIWI Latarissa, Nayla Annida Mamik Ponco Rahayu Marcelina, Ananda Maria Happy Christian Klau Meylisa Nurvita Astari Muhammad Alviyan Shutiawan Muslikh, Faisal Nadia Pramasari Okky Intan Mawarni Pri Hardini Prihardini Prihardini Prihardini Prihardini Priyantri, Risma Virgian R, Herowati Rachma Nurhayati Retno Sofia Sukma Rahayu Reza, Putri Firdaus Shafiera Rizkiawati, Dini Sari PDW, Kumala Sari, Fita Sariwati, Atmira Sya'adah, Puri Zumrotul Winartiana, Winartiana