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Maria Selvester Thadeus
Universitas Pembangunan Nasional Veteran Jakarta
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : Buletin Farmatera

 1 
Potential of Flavonoids on Aortic Histopathological Improvement of ApoE-/- Mice With High-Fat Diet: A Systematic Literature Review Adyatma, Hilmi; Hardini, Niniek; Thadeus, Maria Selvester
Buletin Farmatera Vol 6, No 2 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i2.6358

Abstract

Non-communicable diseases account for more than 36 million deaths every year (63% of all deaths). Globally, non-communicable diseases (NCDs) that cause the most deaths each year are cardiovascular diseases. One of the cardiovascular diseases is coronary heart disease. The cause of coronary heart disease is acute coronary syndrome. More than 90% of acute coronary syndromes (ACS) are the result of atherosclerotic disorders. Therefore, research on the potential of flavonoids to improve histopathology of atherosclerosis needs to be carried out in order to provide information about alternative drugs that can be used by patients. The purpose of this research using a systematic literature review research methodology is to identify the potential of flavonoids to improve aortic histopathology in ApoE-/- mice with a high-fat diet. Systematic literature review by conducting a literature search using PubMed and Google Scholar. Literature that discusses flavonoids, ApoE-/- mice, high-fat diet, aorta, and atherosclerosis. There were 8 studies which concluded that flavonoids could inhibit or reduce the enlargement or further formation of aortic atherosclerotic plaques in ApoE-/- mice on a high-fat diet. Flavonoids have the potential to inhibit or reduce the enlargement or further formation of aortic atherosclerotic plaques in ApoE-/- mice on a high-fat diet.
Co-Authors Abdullah Rukman Adisaputra, Chantika Zahra Adrian Dharmawan Adyatma, Hilmi Agneta Irmarahayu Akbar, Rafi Thoriq Alyani, Fadhilah Sharfina Annisa Afifah Audrey Alvura Digna Basuki Supartono Cahyaninglatri, Wendi Corlia Cut Fauziah Cut Fauziah Cut Fauziah Dimas Farhan Wibawanto Dinda Nuraini Hanifah Wahab Eko Satrio Bahari Erna Harfiani Fachruddin Perdana Fajriati Zulfa Fajriati Zulfa Familia Bella Rahadiati Giopratiwi, Kusvandita Hany Yusmaini Hardini, Niniek Hartono, Riyadi Hikmah Muktamiroh Husna Bunga Jannati Jannati, Husna Bunga Kristina Simanjuntak Kristina Simanjuntak Kristina Simanjuntak Marlina Dewiastuti, Marlina Meiskha Bahar Mila Citrawati Muhammad Alif Farhan Muhammad Kevin Auliansyah Akbar Muktamiroh Hikmah Mumtaz, Syifa Afifah Muttia Amalia Nabila, Inasa Nadira Safa Jasmine Nainggolan, Dorlina Nazira, Syarifah Ni Luh Aurial Widjayanti Niniek Hardini Niniek Hardini Noor Az Zhahra Nooramadhani, Tasya Nugrahayu Widyawardani Nunuk Nugrohowati Nurfitri Bustamam Pamuji, Alifia Shafanaura Pasiak, Taufiq Fredrik Prakoso, Luthfi Octafyan Pujangga, Ibnu Wadud Purba, Raja Soaloon Rahadiati, Familia Bella Ramadhansyah, Reza Reinhart Fikram Imam Akbar Retno Yulianti Retno Yuliyanti Rukman Abdullah Ryan Herardi Salman Paris Salman Paris Setyaningsih, Yuni Simanjuntak, Kristina Soroy Lardo Sri Wahyuningsih Sugeng Wiyono Sukrisno, Adi Tiwuk Susantiningsih Tri Faranita, Tri Uswatun Hasanah Uswatun Hasanah Wahab, Dinda Nuraini Hanifah Wibawanto, Dimas Farhan Yanto Sandy Tjang Yudhi Nugraha Yuliyanti, Retno