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Journal : Jurnal Riset Biologi dan Aplikasinya

The Inhibitory Effect of East Indonesia Endemic Plant Itchy Leaves on Staphylococcus epidermidis as a Normal Skin Flora Malawat, Siti Rabida Nurhasanah; Warella, Juen Carla; Bandjar, Fitri Kadarsih; Effendi, Effendi
Jurnal Riset Biologi dan Aplikasinya Vol. 7 No. 1 (2025)
Publisher : Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jrba.v7n1.p66-76

Abstract

Itchy leaf (Laportea decumana) is one of the plants endemic to Eastern Indonesia. People usually use itchy leaves as an alternative treatment for pain and soreness by rubbing it on the surface of the body. Itchy leaves are very useful because they contain abundant secondary metabolites. The application of itchy leaves by rubbing can certainly affect normal skin flora such as Staphylococcus epidermidis, leading to health problems. This study aimed to investigate the effect of methanol extract of itchy leaves on the normal skin flora of S. epidermidis. This test was conducted using the disk diffusion method. The results of this study showed that all concentrations of itchy leaf extract inhibited the growth of S. epidermidis. The highest inhibitory activity was observed at 50% concentration (23.00 ± 7.20), categorized as very strong, followed by 100% concentration (15.00 ± 2.90), 25% (18.00 ± 11.3), 12.5 (13.40 ± 3.51), and 6.25 (10.40 ± 3.10), all categorized as strong. These findings indicate that the prolonged use of itchy leaves may affect the growth of normal flora, resulting in health problems. On the other hand, itchy leaves have the potential to be developed as an antibacterial agent in the future.
Co-Authors Abbas, Muthmainnah Agung Dwi Wahyu Widodo Alimudi, Saiful Anggun Lestari Husein ASTUTI, EKA Astuty, Eka Augie Desvie Klausya Kadun B. Bension, Johan Bandjar, Fitri Kadarsih Bandjar, Fitri Kardasih Barus, Carolina Sri Athena Christiana Rialine Titaley Cokorda Istri Arintha Devi de Lima, Filda V.I. de Lima, Filda Vionita Irene Dominggus Rumahlatu Dylan Tamalsir Effendi Effendi Eka Astuty Elpira Asmin Elpira Asmin Etrin Zulqarnain Eka Saputra Linggar Fadila Tri Starlia Farah Christina Noya Ferymon Mahulette, Ferymon Filda de Lima Fredy Leiwakabessy Gede Wiratma Jaya Hursepuny, Valentine Husein, Anggun Lestary Indrawanti Kusadhiani Johan B Bension Johan Bruyif Bension Josepina Mainase Kailola, Nathalie E. Kamoda, Tri Puspa Rini Dusung Khairunnida Rahma Latuheru, Grace Lesbatta, Kezia Josawel Limba, Gysella Velove Loupatty, Jeyssen Lincon Makatita, Miftah H Malawat, Siti Rabida Nurhasanah Maxwell Landri Vers Malakauseya Melda Yunita Melda Yunita Melda Yunita Mus, Rosdiana Mutmainnah Abbas Noviyanter Siahaya Novy Gaspersz Noya Van Delzen, Zipora V Noya, Farah C Nurul Fadila Rahmadani Maradjabessy Ohiwal, Morgan Pamella Mercy Papilaya Patteilohy, Merry Prelly Tuapattinaya Rachmawati Dwi Agustin Rahawarin, Halidah Rahaweman, Ayu Christien Ratusehaka, Nopri Rebekah Setiabudi, Rebekah Rumahlatu, Gerce Anne Sekewael, Usi Simal, Rufiati Soumena, Rifah Zafarani Sulfiana Sulfiana SULFIANA, SULFIANA Tahitu, Ritha Tuapattinaya, Prelly M Tuapattinaya, Prelly Marsell Jolanda Tuhumena, Gloria Eka Sari Valentine Hursepunny Veren Wendy Warella Wariunsore, Ayu