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All Journal Journal of Food and Pharmaceutical Science Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Majalah Obat Tradisional Jurnal Farmasi Sains dan Komunitas Jurnal Pengabdian UntukMu NegeRI Jurnal Penelitian Pendidikan IPA (JPPIPA) ALCHEMY Jurnal Penelitian Kimia Jurnal Pengabdian Pada Masyarakat Majalah Farmaseutik JCES (Journal of Character Education Society) JPSCR : Journal of Pharmaceutical Science and Clinical Research PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Ilmu Kefarmasian Indonesia JKPK (Jurnal Kimia dan Pendidikan Kimia) Bubungan Tinggi: Jurnal Pengabdian Masyarakat Madaniya Jurnal Pengabdian Pada Masyarakat Jurnal Pengabdian Kepada Masyarakat Itekes Bali Journal of Food and Pharmaceutical Sciences Journal of Applied Agriculture, Health and Technology
ERMAWATI, DIAN EKA
Sekolah Vokasi, Universitas Sebelas Maret, Surakarta
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Journal : Indonesian Journal of Pharmaceutical Science and Technology

 1 
Characterization of Nanosilver Biosynthesis by Citrus sinensis (L.) Osbeck and Peel-off Mask Formulation with Variation Polyethylene Glycol 400-Glycerin Concentration Dian Eka Ermawati; Agung P. Surya; Adi Yugatama
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 3, No. 1 (2021)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.29875

Abstract

Sweet orange contains flavonoids and citric acid that have the potential as a capping agent in the nanosilver biosynthesis process. The antibacterial activity of silver can be increased in nanoparticles, then it can be applied to treat acne through a peel-off mask preparation. Glycerin and Polyethylene glycol 400 are humectants that combined to obtain good physicochemical properties of the preparation. This study aims to determine the character of nanosilver biosynthesis and the effect of humectant combination on the physicochemical properties of the preparation. The characterization of nanosilver was employed by UV-VIS Spectrophotometry, Particle Size Analysis, and Scanning Electron Microscope. The Glycerin- PEG 400 combination was F1 (0:100%); F2 (25:75%); F3 (50:50%); F4 (75:25%) and F5 (100:0%). The results of nanosilver biosynthesis have an absorption peak of nanoparticles at 421-423nm, rod shape, the particle size of 83.2±7.2nm. Statistical analysis showed that the combination of Glycerin- PEG 400 had a significant effect on organoleptic, viscosity, and dry time, but did not affect the pH of preparation. The combination of Glycerin-PEG 400 (75%:25%) is the best formula because it has stable viscosity, dry time, and pH value during storage for four weeks.Keywords: nanosilver, biosynthesis, Citrus sinensis, humectants, peel off mask
The Optimization of Porang starch-lactose as a co-processed excipient of Bajakah (Spatholobus littoralis Hassk) root dried extract's effervescent tablet Ermawati, Dian Eka; Andini, Bimar Putri; Damayanti, Avina Kusuma
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i1.46521

Abstract

Bajakah root has stronger antioxidant activity than vitamin C. The Dayak people use it to maintain health. Bajakah root infusion has an unpleasant taste and aroma, also unstable, so effervescent tablets are developed to resolve that problem. Effervescent tablets are prepared by direct compression method. The starch of porang tuber is a food that can act as fillers and tablet binders. The co-processed excipient can produce tablet fillers for the directly compressed method. Co-processed excipients of lactose-porang starch have excellent flow properties, improve tablet hardness, have good compatibility, and are cheaper. In this study, the proportions of porang starch and lactose as co-processed excipients were determined using the Simplex Lattice Design method, and then tested the flow properties and granule repose angle. The physical properties of the tablets include weight uniformity, hardness, brittleness, dissolution time, and antioxidant activity test. Test data were analyzed using the One Sample T-test. The results showed that effervescent tablets with co-processed excipient porang starch-lactose 64: 36% provide good physical stability, granule flow time of 10.45 ± 0.29 gram/second, granule repose angle of 27.52 ± 0.95°; tablet weight uniformity with a CV value of 1.021%; tablet hardness 5.74 ± 0.07 Kg, tablet friability of 0.549 ± 0.03%; tablet disintegration time 86 ± 4 seconds. The bajakah root has antioxidant activity of 0.155 mg/mL.
Co-Authors Adi, Lutfan Prastyo Aditya, Shafira Nur Agung P. Surya Agung Putu S.P.Kristyawan Aini S., Aini Alfia Andhika Putri Amaris Susanto, Nindita Clourisa Andini, Bimar Putri Anggraini Febriyanty Anif Nur Artanti Anif Nur Artanti Anif Nur Artanti Anif Nur Artanti, Anif Nur Anjani, Niki Putri Aprilia Saefanan Shofa Cahyarani Intan Ramadhani Cahyarani Intan Ramadhani Damayanti, Avina Kusuma Darojati, Ulfa Afrinurfadhilah Daswati Rofiatun Sahifah David Sarono Putro Dewi, Aptika Oktaviana Trisna Dita Yuli Budiasih Diyah Tri Utami Dyah Ayu Ambarwati Ediati Sasmito Esha ND., Pramitha Farida, Yeni Fea Prihapsara Fea Prihapsara Fea Prihapsara Fridha Angelina Pamuji Galuh Kartikasari H., Muchammad Hanifah, Fitria Lidini Hanuriansyah, Yavi Hayunda I'zaaz Fajrin Heni Utami Prilantari Heru Sasongko Heru Sasongko Heru Sasongko Heru Sasongko Heru Sasongko Hidayati, Astri Husna, Hanna Miftahul Indah Purwantini Indrajati, Dyah Yekti KD, Anggi Kuntari, Tabita Putri M Fiqri Zulpadly M. Fiqri Zulpadly M. Fiqri Zulphadly M. Nur Dewi Kartikasari M. Nur Dewi Kartikasari Megasari, Anis Laela Meitasari, Annisa Diyah Meitasari, Annisa Diyan Muchammad H., Muchammad mufrod mufrod Muhammad Fiqri Zulpadly Nafisa, Fadhila Dian Nailul Maghfiroh ND., Pramitha Esha Niken Rosyana Dewi Septini Nindita Clourisa Amaris Susanto Nindita Clourisa Amaris Susanto Nining Sugihartini Noveri, Priscilla Novi Andriani Novi Andriani Novi Andriani, Novi Nugraha Mas'ud Nuraini, Putri Indah Nurul Rochmawati Prastia, Echa Hana Putriana, Susanti Putro, David Sarono Putu UA., Ni Rahmat S, Anang Kuncoro Raka Sukmabayu W.S Ramadhani, Cahyarani Intan Rido Rohana Tambunan Rochmani, Sholichah Rohmani, Sholicha S., Aini Saifullah Sulaiman Salsabila, Fitri Samrotul Jannah Setyowati, Tri Sholichah Rohmani Sholichah Rohmani Sholichah Rohmani Sholichah Rohmani Sholichah Rohmani, Sholichah siti nurkhasanah Susanto, Nindita Clourisa Amaris Sutarno Sutarno Suwaldi Martodiharjo T.N Saifullah Sulaiman UA., Ni Putu Ul Millah, Nida Ulfa Afrinurfadhilah Darojati Ulfa Afrinurfadhilah Darojati untari, meta kartika Utami, Diyah Tri Villian Septiana Waliyyin Razan Qanit Wisnu Kundarto Wisnu Kundarto Wisnu Kundarto Wisnu Kundarto Wisnu Kundarto Wulandari, Wening Yeni Farida Zulpadly, M. Fiqri Zulpadly, M.Fiqri Zulpadly, Muhammad Fiqri