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All Journal VALENSI Jurnal Pendidikan Kimia Jurnal Pendidikan IPA Indonesia Prosiding Pendidikan Sains INDONESIAN JOURNAL OF PHARMACY Jurnal Penelitian Pendidikan IPA (JPPIPA) PAEDAGOGIA Journal of Economic, Bussines and Accounting (COSTING) Indonesian Journal of Chemistry JKPK (Jurnal Kimia dan Pendidikan Kimia) SAP (Susunan Artikel Pendidikan) SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Jurnal Abdi Masyarakat Indonesia
Elfi Susanti V. H.
Bachelor Program Of Chemistry Education, Faculty Of Teacher Training And Education, Universitas Sebelas Maret, Indonesia Jl.Ir Sutami No 36 A, Surakarta, Central Java, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Engineering Environmental Science Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences

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ACTIVITY TEST OF GUAVA (Psidium guajava L.) LEAF METHANOL EXTRACT AS CONTRACEPTION ANTIFERTILITY TO WHITE MICE (Rattus norvegicus) Sri Retno Dwi Ariani; Endang Susilowati; Elfi Susanti VH; Setiyani Setiyani
Indonesian Journal of Chemistry Vol 8, No 2 (2008)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.846 KB) | DOI: 10.22146/ijc.21632

Abstract

The aim of this research is to know about if the guava (Psidium guajava L.) leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages indicate a positive test as contraception antifertility to white mice (Rattus norvegicus). The sample is guava leaf from Mungkid, Magelang Central of Java Indonesia. The animals experiment are the white mice on 140-300 g for female, 200-250 g for male and about 3 months of age in average. The steps of this research are : (1) preparing  sample, i.e. washing, drying on to indirect sunlight and make the sample into powder, (2) isolation the guava leaf powder in soxhlet instrument with hexane, (3) evaporation the sample with rotary evaporator until guava leaf hexane extract produced, (4) maseration the sample with methanol, (5) evaporation the sample with rotary evaporator until guava leaf methanol extract produced, (6) conducting contraception antifertility activity test to guave leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages to mice white. The results of this research are guava leaf methanol extract on 10.5 mg/mL and 21.0 mg/mL dossages indicate a negative contraception antifertility test to white mice but in these dossages have indicated that an antiimplantation effect (the total natality of fetus is less than the total implantation site in mice white).
Validitas Media Augmented Reality Berbasis Representasi Kimia Tetrahedral dengan Indeks Validasi Aiken Dwi Retno Sari; Sri Yamtinah; Sri Retno Dwi Ariani; Sulistyo Saputro; Elfi Susanti VH; Ari Syahidul Shidiq
Jurnal Penelitian Pendidikan IPA Vol 8 No 6 (2022): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v8i6.2333

Abstract

The development of science and technology has brought significant changes to the world of education, especially in the teaching and learning process. In the learning process, there is an interaction between teachers and students to transform their knowledge in the learning environment. To convey this knowledge, a supporting factor in learning is needed, namely learning media. This study aims to determine the feasibility of chemistry learning media in the form of augmented reality (AR) media based on chemical tetrahedral representations on thermochemical materials. This study uses quantitative research methods, with data processing and analysis using the Aiken model. The instrument used is a validation questionnaire sheet to determine the feasibility of the media. The feasibility test itself is carried out by testing 1 chemist, 1 learning media expert, 1 learning technology expert, and 6 education practitioners. The results of the validation test of the feasibility of augmented reality media get the results of Aiken's V 0.9899, ​​which means that the media is feasible to use. However, improvements still need to be made according to suggestions from the validator so that the finalized product can be used as a measuring tool that meets the criteria.
Development and Characterization of Hand Sanitizer Containing Lempuyang Emprit (Zingiber amaricans BL.) Essential Oil With Zerumbone as The Main Chemical Component Sri Retno Dwi Ariani; Sri Mulyani; Elfi Susanti Vh; Suryadi Budi Utomo; Muhammad Hizbul Wathon; Anastasia Diaz Pramesti
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 8, No 1 (2023): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v8i1.67055

Abstract

Recently, research on the chemistry of natural products as medicinal has been increasingly developed; this is because natural products have many chemical components, have the potential biological activities without side effects, and are easy to obtain. One of these natural products is Lempuyang Emprit (Zingiber amaricans BL.) essential oil. The researchers guided UKM Suti Sehati to develop a new product: a hand sanitizer containing Lempuyang Emprit essential oil (LEEO). This study aims to make ten hand sanitizer formulas by varying LEEO concentrations and determine the best formula based on the physical properties and antibacterial activities. The best formulation obtained was then optimized with variations in fragrance concentration. The best product was selected by a hedonic test using 30 untrained panelists based on the parameters of color, scent, texture, pH, homogeneity, speed of drying, causing no red skin, causing no pain, and causing no dry skin. The antibacterial activity tests were performed against Staphylococcus aureus ATCC 25923 and Escherichia coli ATCC 25922 using the disk method. The LEEO isolation was carried out using steam and water distillation methods, and the chemical components of the best product was identified using the GC-MS method. Based on the hedonic test, the best hand sanitizer product contains 1.5% LEEO and 3% fragrance. This product has a strong antibacterial activity value against S. aureus ATCC 25923, with an inhibition zone of 15.95 mm, and a moderate value against E. coli ATCC 25922, with an inhibition zone of 9.42 mm. The hand sanitizer product contains 21.35% of Zerumbone and exhibits antibacterial and antioxidant capabilities.
Pelatihan dan Pendampingan Produksi Minyak Atsiri Lempuyang Emprit (MALE) dan Hand Sanitizer Beradisi MALE serta Pemasaran Produk secara Digital pada UKM Herbal Suti Sehati di Kabupaten Sukoharjo Jawa Tengah Sri Retno Dwi Ariani; Sri Mulyani; Elfi Susanti VH; Suryadi Budi Utomo; Muhammad Hizbul Wathon; Anastasia Diaz Pramesti; Agustin Wulandari; Aufa Vib Mitsalina
Jurnal Abdi Masyarakat Indonesia Vol 3 No 4 (2023): JAMSI - Juli 2023
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.802

Abstract

UKM Herbal Suti Sehati merupakan salah satu UKM di Jawa Tengah yang mampu bertahan walaupun terjadi pandemi Covid-19. Tujuan kegiatan ini adalah untuk menyelenggarakan pendampingan di bidang produksi, pengemasan, labelisasi, perhitungan analisis kelayakan usaha, dan tata cara pengurusan ijin edar produk minyak atsiri lempuyang emprit (MALE) dan hand sanitizer beradisi MALE, terhadap UKM Suti Sehati, serta pemasaran produk-produknya melalui digital marketing. Permasalahan yang dihadapi oleh UKM adalah: 1) UKM belum memiliki alat distilasi uap-air guna mengisolasi MALE, 2) UKM belum bisa memproduksi MALE dan hand sanitizer beradisi MALE, 3) UKM perlu pendampingan pemasaran produk-produknya melalui digital marketing. Solusi guna mengatasi permasalahan yang ada di UKM adalah, Tim P2M melaksanakan: 1) pemberian hibah alat distilasi uap-air, 2) pendampingan produksi, pengemasan, labelisasi, perhitungan analisis kelayakan usaha dan tata cara pengurusan perijinan usaha produk MALE dan hand sanitizer beradisi MALE, serta 3) memberikan pelatihan digital marketing. Hasil dari kegiatan pelatihan dan pendampingan produksi minyak atsiri lempuyang emprit (MALE) dan hand sanitizer beradisi MALE serta pemasaran produk secara digital terhadap UKM herbal Suti Sehati adalah terwujudnya pemanfaatan tanaman lempuyang emprit yang banyak tumbuh di lahan milik UKM, menambah jenis produk yang dihasilkan oleh UKM, dan peningkatan pendapatan UKM.
Pemberdayaan UKM Suti Sehati melalui Produksi Sabun Herbal Aromaterapi Varian Kamboja, Sedap Malam, dan Kenanga serta Strategi Pemasarannya melalui Instagram Ariani, Sri Retno Dwi; Ulfa, Maria; Vh, Elfi Susanti; Safitri, Nadia Indri; Salim, Eko Nur; Suryani, Adik Annisa Fitri; Zulkarnaen, Rizmoon Nurul
Jurnal Abdi Masyarakat Indonesia Vol 5 No 5 (2025): JAMSI - September 2025
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.2059

Abstract

UKM Suti Sehati merupakan usaha kecil menengah berbasis industri herbal yang berlokasi di Nguter, Sukoharjo, Jawa Tengah. UKM ini menghadapi berbagai permasalahan, antara lain: UKM   sudah memproduksi sabun aromaterapi varian minyak atsiri kunyit dan temugiring dan ingin menambah jenis varian, yaitu varian bunga kamboja, kenanga dan sedap malam; tingginya biaya produksi akibat penggunaan alat distilasi listrik; keterbatasan desain kemasan; labelisasi; dan pemasaran digital; serta belum memahami tata cara perijinan BPOM produk sabun. Guna mengatasi hal tersebut, Tim PKMI-UNS melaksanakan program pemberdayaan melalui penyuluhan, pelatihan, dan pendampingan partisipatif. Kegiatan meliputi: introduksi alat distilasi minyak atsiri, bahan dan alat pembuatan sabun; pelatihan penggunaan alat distilasi minyak atsiri; produksi sabun aromaterapi beradisi  minyak atsiri bunga kamboja, sedap malam, dan kenanga; desain kemasan berlabel; penyuluhan tata cara perizinan BPOM; serta pemasaran digital melalui Instagram. Hasil kegiatan menunjukkan peningkatan keterampilan UKM dalam produksi, efisiensi biaya, kualitas kemasan, dan kemampuan promosi digital. Setelah dua bulan, kegiatan ini berdampak pada peningkatan volume produksi dan distribusi, serta peningkatan pendapatan UKM sebesar 2,0% per bulan secara konsisten. Kegiatan ini  berkontribusi pada SDG 1, 3, 5, 8, 9, 12, dan 17 dengan meningkatkan kesejahteraan, kesehatan, kesetaraan gender, pertumbuhan ekonomi, inovasi berbasis lokal, produksi berkelanjutan, dan kemitraan multipihak.
Search for SARS-CoV-2 Inhibitors. Is it still needed?Molecular Docking Study of Teicoplanin Derivatives and Vancomycin against SARS-CoV-2 Mpro Mulyani, Sri; Lestari, Nova Dwi; Samodra, Imam; Wibowo, Fajar Rakhman; VH, Elfi Susanti; Ardyanto, Tonang Dwi
Jurnal Kimia Valensi Vol. 11 No. 1 (2025): Jurnal Kimia VALENSI
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i1.44709

Abstract

Coronaviruses have been known since 2002 in the case of SARS (Severe Acute Respiratory Syndrome). SARS-CoV-2, the cause of the COVID-19 pandemic, is believed to be an evolution of the SARS-causing coronavirus (SARS-CoV). This evolution shows the complex interaction dynamics between the virus and the host, which have characterized the emergence of new SARS-CoV-2 strain variations until now. Therefore, the search for these antiviral drugs is still critical. MPro is one of the important proteins for the life cycle of pathogenic coronaviruses, so it is an attractive target for developing drugs that inhibit this virus. This study examined the interaction of teicoplanin derivatives and vancomycin as SARS-CoV-2 MPro (6LU7) inhibitors through molecular docking with Autodock Vina. The smallest RMSD value was selected and stored to calculate the energy value. The image of atoms in the ligand and receptor was processed with Autodock Tools, LigPlus, and PyMOL. The study showed that teicoplanin derivatives such as teicoplanin aglycone, teicoplanin-A3-1, and vancomycin had the potential as SARS-CoV-2 Mpro inhibitors. Based on the interaction at the active site and the obtained ΔG values, even the teicoplanin aglycon had a more significant inhibitory potential than other potent inhibitors such as N3.
Co-Authors Adi, Yulia Kristi Agustin Wulandari Anastasia Diaz Pramesti Anastasia Diaz Pramesti Ari Syahidul Shidiq Ashadi, . Asna, Lilis Sofiyatul Aufa Vib Mitsalina Bayu Antrakusuma Catur Saputro, Agung Nugroho Dwi Retno Sari Endang Susilowati Endang Susilowati Fajar Rakhman Wibowo Hartantia, Restika Maulidina Iis Alviah Imam Sri Nugroho Juniar Fauziatul Azizah Lestari, Nova Dwi Lintang Nur Agia Luthfiana, Eva Magdalena, Octaviany Maria Ulfa Martini, Kus Sri Melati Kusuma Wardani Mohammad Masykuri Muhammad Hizbul Wathon Mulatsari, Desi Mulyani, Bakti Mulyani, Sri Mustofa Mustofa Muzzazinah Muzzazinah Nastiti, D. Ninda Dwi Cahya Devi Nurma Yunita Indriyanti Nurma Yunita Indriyanti Nurma Yunita Indriyanti Nurman Perdana, R. Pramesthi, Hilda Nita Rahardjo, S. B. Rahmawati, Ani Ramandika, Muhammad Gunawan Dwi Redjeki, Tri Redjeki, Tri Redjeki, Tri Sabirin Matsjeh Safitri, Nadia Indri Salim, Eko Nur Samodra, Imam Saputro, Agung Nugroho Catur Saputro, Sulistyo Sastika, Agasta Ria Sentot Budi Raharjo Setiawan, Dwi Arief Setiyani Setiyani Sri Mulyani Sri Mulyani Sri Mulyani Sri Mulyani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Retno Dwi Ariani Sri Yamtinah Sugiharto, Sugiharto Sulistyo Saputro Suryadi Budi Utomo Suryadi Budi Utomo Suryadi Budi Utomo Suryani, Adik Annisa Fitri Suryanto, Eko Tonang Dwi Ardyanto Totiana, Fian Tri Prianti Tri Redjeki Tutik Dwi Wahyuningsih Utami, Budi Utomo, Suryadi Budi Widiastuti Agustina Eko Setyowati Wulandari, Lilis Yandi Syukri Zulkarnaen, Rizmoon Nurul