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Journal : Biospecies

UJI EFEKTIVITAS EKSTRAK RIMPANG KUNYIT TERHADAP BAKTERI BACILLUS CEREUS DENGAN PEMBANDING CIPROFLOXACIN Maulidi, Risyad Rizki; Pangaribuan, Novita Helshinta Dewi; Ginting, Frisdayanti Br; Sheridan, Princessa Fath; Lubis, Yolanda Eliza Putri
Biospecies Vol. 13 No. 1 (2020): Januari 2020
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (345.703 KB) | DOI: 10.22437/biospecies.v13i1.8389

Abstract

This research aims to find out effectiveness test of turmeric rhizome in concentration of 25%, 50%, 75% and 100% toward Bacillus cereus bacterial and Ciprofloxacin the same concentration as the comparison. Bacillus cereus Bacteria is a gram-positive rod-shaped bacteria and it is dangerous for humans. This research was conducted with an experimental method with post-test only design and sampling using purposive sampling method. The effectiveness test of turmeric rhizome extract toward Bacillus cereus bacteria was carried out by diffusion using disc paper by calculating the diameter of the bacterial inhibition zone against disc paper that had been moistened with turmeric rhizome extract or Ciprofloxacin solution. The results obtained in this research were carried out with the Post Hoc test, the test was found that there were significant differences from each treatment given with a 95% confidence index. In bacteria treated with 25% ciprofloxacin toward Bacillus cereus, the effectiveness was above 50% turmeric rhizome extract and under 75% turmeric extract. Turmeric extract of 75% 10.6 mm had bacterial effect as Ciprofloxacin 25% of 10.1 mm toward the growth of Bacillus cereus bacterial.
- Uji Efektivitas Ekstrak Bunga Pepaya (Carrica papaya L.) Terhadap Kadar Gula Darah Mencit (Mus musculus L.) Jantan Yang Diinduksi Sukrosa: Uji Efetivitas Ekstrak Bunga Pepaya (Carrica Papaya L.) Terhadap Kadar Gula Darah Mencit (Mus Musculus L.) Jantan Yang Diinduksi Sukrosa Marpaung, Febri Sri; Tampubolon, Ester Juanita br.; Andika, Muhammad Insan; Lubis, Yolanda Eliza Putri; Mutia, Maya Sari
Biospecies Vol. 14 No. 1 (2021): Januari 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11175

Abstract

The papaya (Carica papaya L) flower contain flavonoids, tannins, and triterpenoid steroids which function as antidiabetic. This study was conducted to determine the antidiabetic effect of papaya (Carica papaya L) flower extract on sucrose-induced male mice. In this study, mice were made diabetic by inducing them with sucrose at a dose of 160 mg/kg BW. A total of 25 mice were grouped homogeneously into 5 groups, consisting of a negative control group (CMC 0.5%), a positive control group (no administration), a group with a dose of 200 mg/kg BW, a group with a dose of 400 mg/Kg. BW, and the group with a dose of 500 mg/Kg BW. Measurement of blood sugar levels of mice was carried out before administration of sucrose, after administration of sucrose and after administration of papaya flower extract. The results showed that the three doses had an antidiabetic effect, and the administration of papaya flower extract at a dose of 200 mg/Kg BW showed a better effect than the negative control.
- Uji Efektivitas Ekstrak Etanol Kulit Jeruk Sunkist (Citrus sinensis (L.) Osbeck) Terhadap Kadar Gula Darah Tikus Wistar (Rattus norvegicus) dengan Hiperkolesterolemia yang di Induksi Streptozotocin. : UJI EFEKTIVITAS EKSTRAK ETANOL KULIT JERUK SUNKIST (Citrus sinensis (L.) Osbeck) TERHADAP KADAR GULA DARAH TIKUS WISTAR (Rattus norvegicus) DENGAN HIPERKOLESTEROLEMIA YANG DI INDUKSI STREPTOZOTOCIN Depari, Sania Angelisa F; Rambe, Daffa Jihan Azmi; Meilando, Rifki; Lisya, Cut; Mutia, Maya Sari; Lubis, Yolanda Eliza Putri
Biospecies Vol. 14 No. 1 (2021): Januari 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11250

Abstract

The Condition of high blood sugar levels in people with diabetets appears to trigger an increase in LDL and decrease HDL level where in people with diabetes the energy obtained by the body comes from the decomposition of fat and protein metabolism.”Sunkist orange peel (Citrus sinensis (L.) Osbeck) is reported to have antidiabetic, anti-hypercholesterolemia, anti-inflammatory and antioxidant activities. This study aims to find out the effectiveness of Sunkist orange peel ethanol extract (Citrus sinensis (L.) Osbeck) on blood sugar levels at doses of 500, 750 and 1000 mg/kgBB. This study used the True Experimental Pre-Test and Post-Test Control Group as research design where sunkist orange peel was extracted by maceration method and was given orally for 14 days to streptozotocin induced wistar rat with hypercholesterolemia. Statistical test results showed that ethanol extract of Sunkist orange peel was able to lower blood sugar levels and cholesterol levels of h streptozotocin induced wistar rat with hypercholesterolemia (p<0.05). The most effective dose of Sunkist orange peel ethanol extract in lowering blood sugar levels and cholesterol levels of streptozotocin induced wistar rat with hypercholesterolemia is 1000mg/kgBB.
Co-Authors Aipin, Anggi Sri Ananda Aleksander Marganda Sidebang Ananda, Rayhan Khozin Aulia Andika, Muhammad Insan Annisa Amalia Arianti, Rahmi Aulia, Nathasyia Br Sitepu, Rachel Maria Cruz Jovanca Buaya, Adjani Chrismis Novalinda Ginting Chrismis Novalinda Ginting Christine Wira Dika Juliana Halawa Claudia Malau, Reghita Claudya Claudya Davin, Radhitya Qowiyyul Delfian, Taufik Depari, Sania Angelisa F Dewani Silaban, Grace Diaz F. Izdihar Doladave, Miguelle Franklin Dwi Surya Artie Edlin, Edlin Ermi Girsang Evan charista ziraluo Faridahanum, Faridahanum Ginting, Chrismis Novalinda Ginting, Frisdayanti Br Girsang , Ermi Girsang, Ermi Gurusinga, Fransisco Bastanta Hamsi, Ulpah Zahara Hanjaya Hasan Basri Nasution, Muhammad Husni Lubis, Muhammad I Nyoman Ehrich Lister Ishak, Muhammad Raihan Ismardi, Dita Anisa Kaban, Karmila Katherine Gunawan Laia, Lisbetaria Lawrence, Christopher Lestari Nasution, Sri Lina, Juliana Lisya, Cut Lumban Gaol, Nova Elisabeth Lumbantobing, Christina J.R.E. Manao, Oktoriadi Manurung, Charles Marpaung, Febri Sri Marpaung, Febri Sri Astuti Maulidi, Risyad Rizki Maya Sari Mutia Maya Sari Mutia Meilando, Rifki Monica, Veny Mughni Muchtar, Aisyah Muhammad Yunus Mutia, Maya Sari Nabila, Putri Nadeak, Gideon Nadi, Edlin Napiah Nasution, Ali Nardi, Leo Nasution, Masdalena Nazara, Niscaya Aprian Pangaribuan, Novita Helshinta Dewi Pearlie, Michelle Maydelaine Pratomo, Fransiskus Aryo Pulungan, Ica Yulianti Purboningtyas, Dyah Nisma Puspawani , Yeni Puspawani, Yeni Putranto Manalu Putri Handayani Putri, Shafyra Mahdyah Ramadhini, Amelya Putri Ramazata, Bayu Rambe, Daffa Jihan Azmi Rena Meutia Rizal Rizal Rizky, Muhammad Irvan Roland Daniel Theodore Amudi Matondang Rya Sianturi , Agnes Sari Mutia, Maya Sari, Ajeng Mestika Sarumaha, Abrianus Sheridan, Princessa Fath Silitonga, Impola Dinita Felicia Sitepu, Bintang Darma M Soekardi, Adi Sri Astuti Marpaung, Febri Sri Lestari Sri Wahyuni Stevenie - Suandy , Suandy Suandy, Suandy Suhartomi Tafonao, Rachel Julia Tampubolon, Ester Juanita Tampubolon, Ester Juanita br. Teguh Kurniawan, Dendy Therry Prosperita K. Wau Wahyu Setia Widodo Wahyu Widowati Wahyuni Nasution, Sri Widya Yanti Sihotang Zahra, Annisa Alsadilla Zuhra, Layla