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Assasement and Experimental Procedure Polycystic Ovary Syndrome Rat Model: Review Kurniawati, Erna Yovi; Pramono, Noor; Hidayat, Syarief Thaufik; Mahati, Endang
Jurnal Sain Peternakan Indonesia Vol 18 No 4 (2023)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31186/jspi.id.18.4.242-256

Abstract

A complicated endocrine condition that affects many women worldwide is called polycystic ovarian syndrome, or PCOS. The use of rat models has greatly aided research on many facets of PCOS. In addition to discussing the parameters, evaluation techniques, and indicators pertinent to PCOS research, this study evaluates the standard circumstances of PCOS rat models. Our knowledge of PCOS has improved due to investigating endocrine, hormonal, inflammatory, oxidative stress, metabolic, genetic, and microbiota-related factors in these models. The results highlight how important it is to use PCOS rat models to understand the complexities of this illness and offer possible treatment avenues.
The Effect of Zikr Meditation on Anxiety, Stress Levels and Blood Pressure in Hypertensive Patients Kurniawati, Erna Yovi; Sari, Dian Nirmala
Journal of Rural Community Nursing Practice Vol. 2 No. 2 (2024): September
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v2i2.396

Abstract

Background: Hypertension, a prevalent chronic condition, poses significant health risks when left untreated. Psychological factors like stress and anxiety are known contributors to high blood pressure. Effective management of hypertension may benefit from non-pharmacological interventions that address these psychological elements. Purpose: This study aims to evaluate the impact of Zikr meditation, a spiritual mindfulness practice, on reducing anxiety, stress, and blood pressure in individuals with hypertension. Methods: A double-blind randomized controlled trial was conducted with 60 hypertensive patients, randomized into intervention and control groups. The intervention group participated in 20-minute Zikr meditation sessions for four weeks daily, while the control group engaged in a placebo activity. Anxiety and stress levels were measured using the Hamilton Anxiety Rating Scale (HAM-A) and the Perceived Stress Scale (PSS), respectively. Blood pressure readings were taken before and after the intervention. Results: Participants in the Zikr meditation group showed a significant reduction in anxiety and stress levels compared to the control group. Additionally, there was a notable decrease in systolic and diastolic blood pressure among those practicing Zikr meditation. Conclusions: Zikr meditation effectively reduces anxiety and stress, leading to lower blood pressure in hypertensive patients. These findings suggest that incorporating Zikr meditation into standard hypertension management could offer a valuable, non-pharmacological approach to improving cardiovascular health. Further research is recommended to examine Zikr meditation's long-term effects and broader applicability in hypertension care.
Stres, Kecemasan dan Kadar Kortisol Serum Wanita dengan Sindrom Ovarium Polikistik (SOPK) Kurniawati, Erna Yovi; Hadisaputro, Suharyo; Suwandono, Agus
JURNAL KESEHATAN REPRODUKSI Vol 10, No 3 (2023)
Publisher : Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jkr.72468

Abstract

Latar Belakang: SOPK dikaitkan dengan risiko kesehatan mental jangka panjang seperti disfungsi seksual, gangguan kesehatan, gangguan mood, kecemasan, dan depresi. Kadar kortisol mempengaruhi fungsi endokrin lain dalam tubuh dan dapat mempengaruhi resistensi insulin dan anovulasi.Tujuan: Mengetahui tingkat stress, tingkat kecemasan dan kadar kortisol serum wanita dengan sindrom ovarium polikistik (SOPK)Metode: Penelitian deskriptif, metode sampel pusposive sampling dengan jumlah responden 30 wanita dengan sindrom ovarium polikistik di Yogyakarta. Instrumentasi menggunakan Kuesioner State Anxiety dan Trait Anxiety (STAI), Perceived Stress Scale-10 (PSS-10), dan Kadar kortisol serum dengan ELISA di LPPT UGM.Hasil dan Pembahasan: Seluruh responden mengalami kecemasan, sebesar 53% responden mengalami kecemasan berat, dan seluruh responden mengalami tingkat stress berat. Rerata kadar kortisol serum 124.98 mcg/dl.Kesimpulan: Faktor psikologis sebagai indikator psikologis yang perlu dicegah atau dikelola saat merawat SOPK. Kombinasi terapi fisik dan psikoterapi atau mindfulness diperlukan untuk efektivitas terapi yang optimal.
EDUKASI BISNIS UNTUK MENGATASI HAMBATAN BISNIS UMKM TEA BREAK DALAM MELAKUKAN PERLUASAN BISNIS Jati, L. Jatmiko; Kurniawati, Erna Yovi; Wardhana, Helna; Khairi, Widayatul
JUAN: Jurnal Pengabdian Nusantara Vol. 1 No. 1 (2024): Januari 2024
Publisher : CV Sentra Nusa Connection

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63545/juan.v1.i1.3

Abstract

This activity explores and educates how a company carries out long-term strategic planning in expanding or expanding its business, where in carrying out expansion and expansion there are of course obstacles and obstacles it faces. Therefore, it is important for a company's strategic planning to overcome the obstacles and obstacles faced in expanding and expanding its business so that it remains stable and competitive. This activity focuses on one of the micro, small and medium enterprises, namely the beverage industry company "Tea Break" which is located in Selaparang sub-district, Rembiga, Mataram City. The results of this activity highlight the importance of company strategic planning in carrying out business expansion and expansion as well as how companies deal with the obstacles and obstacles they face. The results show that the education carried out by the Team has increased the understanding of MSME owners in carrying out expansion.
WORKSHOP MANAJEMEN PERUBAHAN UNTUK MENINGKATKAN PRESTASI MAHASISWA Jati, L. Jatmiko; Widiyasti, Baiq Dinna; Kurniawati, Erna Yovi
JUAN: Jurnal Pengabdian Nusantara Vol. 1 No. 2 (2024): April 2024
Publisher : CV Sentra Nusa Connection

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63545/juan.v1.i2.18

Abstract

Workshop ini bertujuan untuk memberikan pemahaman yang mendalam tentang pentingnya manajemen perubahan dalam konteks pendidikan tinggi untuk meningkatkan prestasi mahasiswa. Workshop ini ditujukan kepada mahasiswa dari disiplin ilmu manajemen (agar mereka dapat mengaplikasikan konsep-konsep yang dipelajari dalam kegiatan akademik dan kehidupan sehari-hari mereka. Peserta workshop dibimbing melalui diskusi interaktif, studi kasus, dan simulasi untuk memahami bagaimana perubahan dapat memengaruhi berbagai aspek kehidupan mahasiswa, termasuk akademik, sosial, dan emosional. Mereka akan belajar tentang teknik-teknik manajemen waktu, pengaturan prioritas, komunikasi efektif, dan pengelolaan stres untuk membantu mereka menghadapi perubahan dengan lebih baik dan meningkatkan kinerja akademik mereka. Workshop ini diharapkan dapat menjadi langkah awal bagi peserta untuk mengembangkan kemampuan manajemen perubahan yang akan membantu mereka mencapai prestasi akademik yang lebih baik dan sukses di masa depan.
Experimental animal models for polycystic ovarian syndrome (methods, effects, and implications) Erna Yovi Kurniawati; Noor Pramono; Syarief Thaufik Hidayat; Endang Mahati
Livestock and Animal Research Vol 22, No 1 (2024): Livestock and Animal Research
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/lar.v22i1.79197

Abstract

Many studies have replicated the clinical and genetic features of polycystic ovarian syndrome (PCOS) using a range of experimental animal models to improve treatment outcomes. This article aims to present an overview of the various experimental animal models that have been used in PCOS research. In this study, we conducted a systematic review of relevant research articles on the induced animal model PCOS. We searched research articles in Indonesian and English published over the last five years through three databases: PubMed, ScienceDirect, Google Scholar. We use established inclusion and exclusion criteria to select suitable articles. Out of 19 research articles included in our systematic review, we found the animal model PCOS based Rotterdam criteria, PCOS-IR model, PCOS-Inflammation model, PCOS-Gut microbiota model and PCOS-syndrome metabolic model. Androgen agents such as testosterone propionate, free testosterone, DHEA, and letrozole, as well as sodium valproate, are effective in the induction of PCOS phenotypes based on the Rotterdam criteria (oligo/amenorrhea, hyperandrogenic, and polycystic ovaries).
Understanding The Influencing Factors in The Onset of PCOS: A Review Kurniawati, Erna Yovi
Jurnal Keperawatan Komplementer Holistic Vol. 3 No. 1 (2025): Volume 3 No. 1 2025
Publisher : Yayasan Healing and Healthcare Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12345/jkkhc.v3i1.79

Abstract

Polycystic ovary syndrome (PCOS) is an endocrine disorder prevalent in women of reproductive age. This comprehensive review aims to shed light on the various factors that contribute to the onset and progression of PCOS. The analysis includes a thorough exploration of genetic predisposition, environmental influences, and lifestyle factors in the context of their role in the hormonal dysregulation, insulin resistance and ovarian dysfunction associated with PCOS. The complex relationship between these factors and the clinical manifestations of PCOS, including irregular menstrual cycles, hyperandrogenism, and polycystic ovarian morphology, is also discussed. By synthesizing current research findings, this review provides a comprehensive understanding of the various factors that influence the occurrence of PCOS, offering valuable insights for reference in reproductive health education, early detection of PCOS, and development of comprehensive prevention and intervention combinations.
Efficacy of Bay Leaf (Syzygium polyanthum) Decoction in Managing Type 2 Diabetes Mellitus Patients: A Randomized Controlled Trial Kurniawati, Erna Yovi; Muhlida, Vinilia Ihramatul; Dewi, Mariza Mustika; Margiyati
Journal of Rural Community Nursing Practice Vol. 3 No. 1 (2025): March
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v3i1.462

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycaemia, leading to complications such as cardiovascular disease and kidney failure. The increasing prevalence of T2DM necessitates effective management strategies, including complementary therapies like bay leaf (Syzygium polyanthum), which has demonstrated potential for glycaemic control. Purpose: This study aimed to evaluate the effectiveness of bay leaf decoction in improving glycaemic control among T2DM patients in Malangan Village. Methods: A randomized controlled trial (RCT) involved 60 adults aged 30-65 years with fasting blood sugar (FBS) levels between 126-200 mg/dL, selected through purposive sampling. Participants were randomly assigned to an intervention group receiving a bay leaf decoction (10 grams in 250 mL water, twice daily for 12 weeks) or a control group receiving a placebo decoction. Primary outcomes included changes in FBS, while secondary outcomes assessed postprandial blood sugar (PBS) and HbA1c. Compliance and adverse events were monitored, and data were analysed using paired and independent t-tests (p < 0.05). Results: The intervention group showed significant reductions in FBS, PBS, and HbA1c levels compared to the control group (p < 0.05). Older age, female gender, and higher education correlated with improved glycaemic control, while obesity and hypertension were associated with poorer outcomes. No severe adverse events were reported. Conclusion: Bay leaf decoction significantly improves glycaemic control through mechanisms such as enhanced insulin sensitivity, α-glucosidase inhibition, and antioxidant properties. This natural, cost-effective approach is promising as a complementary therapy for T2DM. Future research should explore long-term effects, optimal dosage, and integration with lifestyle interventions to maximize benefits.
The Effect of Zikr Meditation on Anxiety, Stress Levels and Blood Pressure in Hypertensive Patients Kurniawati, Erna Yovi; Sari, Dian Nirmala
Journal of Rural Community Nursing Practice Vol. 2 No. 2 (2024): September
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v2i2.396

Abstract

Background: Hypertension, a prevalent chronic condition, poses significant health risks when left untreated. Psychological factors like stress and anxiety are known contributors to high blood pressure. Effective management of hypertension may benefit from non-pharmacological interventions that address these psychological elements. Purpose: This study aims to evaluate the impact of Zikr meditation, a spiritual mindfulness practice, on reducing anxiety, stress, and blood pressure in individuals with hypertension. Methods: A double-blind randomized controlled trial was conducted with 60 hypertensive patients, randomized into intervention and control groups. The intervention group participated in 20-minute Zikr meditation sessions for four weeks daily, while the control group engaged in a placebo activity. Anxiety and stress levels were measured using the Hamilton Anxiety Rating Scale (HAM-A) and the Perceived Stress Scale (PSS), respectively. Blood pressure readings were taken before and after the intervention. Results: Participants in the Zikr meditation group showed a significant reduction in anxiety and stress levels compared to the control group. Additionally, there was a notable decrease in systolic and diastolic blood pressure among those practicing Zikr meditation. Conclusions: Zikr meditation effectively reduces anxiety and stress, leading to lower blood pressure in hypertensive patients. These findings suggest that incorporating Zikr meditation into standard hypertension management could offer a valuable, non-pharmacological approach to improving cardiovascular health. Further research is recommended to examine Zikr meditation's long-term effects and broader applicability in hypertension care.
Efficacy of Bay Leaf (Syzygium polyanthum) Decoction in Managing Type 2 Diabetes Mellitus Patients: A Randomized Controlled Trial Kurniawati, Erna Yovi; Muhlida, Vinilia Ihramatul; Dewi, Mariza Mustika; Margiyati
Journal of Rural Community Nursing Practice Vol. 3 No. 1 (2025): March
Publisher : Al-Hijrah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58545/jrcnp.v3i1.462

Abstract

Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by hyperglycaemia, leading to complications such as cardiovascular disease and kidney failure. The increasing prevalence of T2DM necessitates effective management strategies, including complementary therapies like bay leaf (Syzygium polyanthum), which has demonstrated potential for glycaemic control. Purpose: This study aimed to evaluate the effectiveness of bay leaf decoction in improving glycaemic control among T2DM patients in Malangan Village. Methods: A randomized controlled trial (RCT) involved 60 adults aged 30-65 years with fasting blood sugar (FBS) levels between 126-200 mg/dL, selected through purposive sampling. Participants were randomly assigned to an intervention group receiving a bay leaf decoction (10 grams in 250 mL water, twice daily for 12 weeks) or a control group receiving a placebo decoction. Primary outcomes included changes in FBS, while secondary outcomes assessed postprandial blood sugar (PBS) and HbA1c. Compliance and adverse events were monitored, and data were analysed using paired and independent t-tests (p < 0.05). Results: The intervention group showed significant reductions in FBS, PBS, and HbA1c levels compared to the control group (p < 0.05). Older age, female gender, and higher education correlated with improved glycaemic control, while obesity and hypertension were associated with poorer outcomes. No severe adverse events were reported. Conclusion: Bay leaf decoction significantly improves glycaemic control through mechanisms such as enhanced insulin sensitivity, α-glucosidase inhibition, and antioxidant properties. This natural, cost-effective approach is promising as a complementary therapy for T2DM. Future research should explore long-term effects, optimal dosage, and integration with lifestyle interventions to maximize benefits.