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OPTIMIZING STUNTING PREVENTION: KEY DETERMINANTS IN BANJARNEGARA REGENCY Sari, Dian Nirmala; Fajri, Umi Nur; Fauziah, Nur Alfi; Kurniawati, Erna Yovi
Journal Healthcare Education Vol. 3 No. 2 (2025): Volume 3 No. 2 2025
Publisher : Yayasan Healing and Healthcare Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/jhce.v3i2.87

Abstract

The incidence of stunting in toddlers is a major nutritional issue in Indonesia. Data from the Nutrition Status Monitoring (PSG) over the past three years shows that stunting has the highest prevalence compared to other nutritional problems such as underweight, wasting, and obesity. The prevalence of stunting in toddlers increased from 27.5% in 2016 to 29.6% in 2017. Various factors influence the occurrence of stunting; however, these factors can vary by region. Detailed data on the determinants of stunting in children is crucial for informing government policies in addressing public health issues, particularly stunting. This study focuses on Banjarnegara Regency, which ranks among the top five regions with the highest stunting rates in Central Java. The objective of this research is to analyze the factors influencing stunting among children aged 2-5 years in Banjarnegara Regency. This quantitative study uses a case-control approach, with a population of all children aged 2-5 years. Data analysis includes univariate descriptive analysis and bivariate analysis using the Chi-Square test. The results indicate that education, economic status, environment, and birth length are associated with stunting in toddlers, whereas exclusive breastfeeding history is not associated with stunting.
EFFECT OF CLITORIA TERNATEA ON FOLLICULOGENESIS POLYCISTIC OVARY SYNDROME: IN SILICO STUDY ON LUTEINIZINNG HORMONE RECEPTOR Kurniawati, Erna Yovi; Muhlida, Vinilia Ihramatul
Journal Healthcare Education Vol. 3 No. 2 (2025): Volume 3 No. 2 2025
Publisher : Yayasan Healing and Healthcare Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.1234/jhce.v3i2.90

Abstract

Polycystic Ovary Syndrome (PCOS) is a complex hormonal disorder involving dysregulation of luteinizing hormone (LH) and its receptor, leading to menstrual irregularities and anovulation. This study evaluates the potential of Clitoria ternatea, a traditional medicinal plant, in modulating LH receptor activity through in silico analysis. Methods: Active compounds from Clitoria ternatea, including flavonols (kaempferol, isorhamnetin), flavones (baicalein, luteolin, apigenin), phenolic acids (chlorogenic, protocatechuic, gallic), and epicathechin, were identified via PubChem. Lipinski’s rule and LD50 classifications were used to assess drug-like properties and toxicity. Bioactivity was predicted using PASS Online, SwissTarget Prediction, PharmMapper, and SuperPred. The LH receptor's 3D structure was modeled using Swiss Model and validated with Procheck and Errat Check. Molecular docking studies using PyRx assessed binding affinities between the compounds, spironolactone, flutamide, and the LH receptor. Results: Docking results revealed strong binding affinities of Clitoria ternatea compounds with the LH receptor, particularly phenolic acids and flavonoids, showing comparable or better interactions than spironolactone and flutamide. These interactions suggest a potential role in restoring hormonal balance and ovulatory function. The study highlights the therapeutic potential of Clitoria ternatea for PCOS management. Its compounds demonstrate significant LH receptor interactions, offering a promising basis for further research. Conclusion: Clitoria ternatea shows promise as a natural therapeutic candidate for PCOS. Future in vitro, in vivo, and clinical trials are needed to validate these findings
The Role of Midwives in the Early Detection of Infertility Risk Factors Among Women of Reproductive Age Kurniawati, Erna Yovi; Iriyani, Elfrida
PubHealth Jurnal Kesehatan Masyarakat Vol. 4 No. 1 (2025): Edisi Juli
Publisher : Ilmu Bersama Center

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56211/pubhealth.v4i1.1064

Abstract

Primary infertility is an increasingly prevalent reproductive health issue, yet it often remains undetected at the primary care level. Midwives, as frontline health professionals, hold strategic potential in the early identification of infertility risk through maternal and child health (MCH) services. This study aimed to analyze the relationship between patients’ perceptions of midwives’ roles and the identification of infertility risk factors among couples of reproductive ages. This study employed a cross-sectional design with a quantitative approach. The sample consisted of 32 reproductive-age couples attending MCH services in Yogyakarta, Indonesia. Data were collected using a structured questionnaire assessing perceptions of midwives’ roles across five dimensions: education, early detection, counseling, referral, and communication. Data analysis included chi-square tests and multivariate logistic regression. A significant association was found between positive perceptions of midwives’ roles in education (p=0.041), early detection (p=0.018), and communication (p=0.029) with successful identification of infertility risk factors. Early detection emerged as the most dominant factor (OR=3.47; 95% CI=1.29–9.31).  Midwives' roles in early detection, education, and communication significantly contribute to identifying infertility risk factors. Strengthening midwives’ authority and capacity in fertility-related issues is essential to promote a sustainable preventive approach in primary health care.
Effect of Clitoria ternatea on Androgen Receptor: Molecular Docking Study Kurniawati, Erna Yovi; Muhlida, Vinilia Ihramatul
Infomasi dan Promosi Kesehatan Vol 4 No 2 (2025): Informasi dan Promosi Kesehatan
Publisher : Sahabat Publikasi Kuu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58439/ipk.v4i2.374

Abstract

Introduction: Polycystic Ovary Syndrome (PCOS) is a complex hormonal disorder that affects many women worldwide, characterized in part by elevated androgen levels that can lead to various health complications. Traditional medicinal plants, such as Clitoria ternatea, have been explored as potential therapeutic agents for managing PCOS. Methods: This study employed an in silico approach to evaluate the interaction between active compounds in Clitoria ternatea and the androgen receptor. Molecular docking, molecular dynamics simulations, and binding affinity analyses were conducted to assess the potential of these compounds in modulating androgen receptor activity Results: The computational analysis revealed that several active compounds in Clitoria ternatea exhibited favorable binding interactions with the androgen receptor, indicating a potential to modulate its activity. These compounds demonstrated stable interactions and promising binding energies in the molecular simulations. Conclusion These findings suggest that Clitoria ternatea may play a role in managing PCOS through modulation of androgen receptor activity. However, further in vitro and in vivo studies are required to validate these computational results and explore their therapeutic potential in clinical settings.
Tingkat Kecemasan, Stres, dan Depresi pada Wanita yang Menjalani Program In Vitro Fertilization (IVF) Kurniawati, Erna Yovi; Devaisnaini, Arsita Rahma
Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Vol. 3 No. 4 (2025): Desember : Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebida
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/corona.v3i4.1407

Abstract

This study aims to describe the level of anxiety, stress, and depression in women undergoing In Vitro Fertilization (IVF) program and to see the distribution of psychological disorders based on sociodemographic characteristics and the stage of IVF program undertaken. The design of this study was descriptive quantitative with purposive sampling technique on 28 women who were undergoing IVF cycles in infertility clinics in Yogyakarta Special Region. Data were collected online through a questionnaire containing Hamilton Anxiety Rating Scale (HARS), Perceived Stress Scale (PSS), and Beck Depression Inventory-II (BDI-II) instruments. Descriptive analysis showed that most respondents experienced moderate anxiety (42%), mild stress (38%), and mild depression (36%). The analysis also showed that sociodemographic characteristics, such as age older than 35 years, non-working employment status, and low education, had a higher tendency towards psychological disorders. In addition, certain phases of IVF, such as the waiting phase after embryo transfer, appeared to be associated with increased levels of anxiety and stress. This study emphasizes the importance of more intensive psychological support, especially for women who are in the more stressful stages of IVF, as well as for those with sociodemographic risk factors that increase their vulnerability to psychological disorders.
Age, BMI, and Medical History as Determinants of Infertility in Women of Reproductive Age Kurniawati, Erna Yovi; Hidayat, Syarief Thaufik
Jurnal Promotif Preventif Vol 8 No 5 (2025): Oktober 2025: JURNAL PROMOTIF PREVENTIF
Publisher : Fakultas Kesehatan Masyarakat Universitas Pancasakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47650/jpp.v8i5.2090

Abstract

Infertility is a complex, multifactorial condition influenced by various biological and lifestyle-related risk factors. This study aimed to examine the association between age, body mass index (BMI), and medical history with infertility among women of reproductive age. A cross-sectional analytical study was conducted among 180 women of reproductive age attending primary and secondary healthcare facilities in Yogyakarta and Central Java. Data were collected through structured interviews, anthropometric assessments, and medical record verification. Variables included age, BMI, relevant reproductive medical history (e.g., PCOS, thyroid disorders, endometriosis), and fertility status. Bivariate analyses and binary logistic regression were employed to identify significant predictors of infertility. The prevalence of infertility was 38.9%, with primary infertility comprising 62.9% of cases. Age ≥35 years (OR = 4.71; 95% CI: 2.10–10.57), abnormal BMI (OR = 3.97; 95% CI: 1.81–8.71), and reproductive-related illnesses (OR = 4.23; 95% CI: 1.97–9.08) were independently and significantly associated with infertility (p < 0.001 for all). These factors impair fertility through mechanisms involving hormonal dysregulation, metabolic imbalance, and chronic inflammation. Advanced maternal age, BMI deviations, and reproductive comorbidities are critical determinants of infertility among women of reproductive age. This study underscores the urgency of individualized fertility care within reproductive health strategies. Longitudinal and biomarker-based studies are recommended to further elucidate causal pathways and incorporate male infertility parameters.
Household Chemical Exposure and Infertility in Reproductive Age Couples Living in Agricultural Regions of Yogyakarta Kurniawati, Erna Yovi; Rizkiana, Erin
Jurnal Epidemiologi Kesehatan Komunitas Vol 10, No 4: November 2025
Publisher : Master of Epidemiology, Faculty of Public Health, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jekk.v10i4.28622

Abstract

Background : Exposure to household chemicals, especially those containing endocrine-disrupting compounds, can cause serious damage to reproductive health. These findings highlight the importance of developing and implementing preventive environmental health strategies. Policies should be designed to integrate ecological-reproductive risk management, particularly targeting rural communities that experience high exposure to household and agricultural chemicals.Methods : This cross-sectional epidemiological study involved 48 couples of reproductive age, selected using cluster-stratified sampling in rural agricultural areas. Data collection included structured interviews and household observations to assess exposure to common household chemicals such as floor cleaners, aerosol air fresheners, and pesticide residues.  Statistical analysis involved univariate and bivariate tests (Chi-square), as well as multivariate logistic regression, to determine independent relationships.Result: The prevalence of primary infertility was 35.4%. Bivariate analysis revealed significant associations between infertility and exposure to floor cleaners (p = 0.021), air fresheners (p = 0.034), and indoor pesticide residues (p = 0.015). Multivariate analysis confirmed indoor pesticide exposure (aOR = 3.92; 95% CI : 1.12–13.68) and air freshener use (aOR = 2.74; 95% CI : 1.01–9.15) as independent predictors of infertility.Conclusion: Exposure to household chemicals can cause serious damage to reproductive health. This risk increases when such exposure is combined with agricultural chemicals. These findings highlight the importance of developing and implementing preventive environmental health strategies. Policies should be designed to integrate ecological-reproductive risk management, particularly targeting rural communities that experience high exposure to household and agricultural chemicals.
Knowledge Levels of Pre-Marital Couples on Stunting Prevention after the Exposure to an E-Module Romadhoni, Intan; Kurniawati, Erna Yovi; Iriyani, Elfrida
Agribiohealth (Journal of Agriculture, Biology & Health Sciences) Vol. 1 No. 1 (2024): Agribiohealth (Journal of Agriculture, Biology & Health Sciences)
Publisher : Medico Insight Innovation Initiative

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65318/agribiohealth.v1i1.1

Abstract

Stunting is a significant public health issue affecting children under five, commonly resulting from chronic malnutrition and infections during early childhood. This descriptive study was conducted in 2023 at the Marriage Registration Office (KUA) in Imogiri sub-district, an area selected due to high stunting rates in the villages of Jatimulyo, Muntuk, and Karangtengah. The study aimed to assess the knowledge levels of pre-marital couples regarding stunting prevention after exposure to a digital e-module. Using purposive sampling, 15 respondents were selected based on their willingness to participate and ability to complete the module. The e-module was chosen for its accessibility, scalability, and interactive features, making it suitable for reaching a broad audience and accommodating varied learning paces. Pretest and posttest assessments demonstrated that the e-module effectively improved participants’ knowledge, as shown by a notable increase in average posttest scores. These results highlight the potential benefits of incorporating digital health education into pre-marital counseling programs to raise awareness on stunting prevention. Future efforts should consider adapting this module to diverse cultural contexts and evaluating its role within a broader national health strategy to support child health outcomes in Indonesia.
Cabbage Leaf Compress (Brassica oleracea): A Natural Remedy for Reducing Breast Engorgement Pain in Postpartum Dewi, Mariza Mustika; Kurniawati, Erna Yovi; Rochkmana, Meika Jaya
Agribiohealth (Journal of Agriculture, Biology & Health Sciences) Vol. 1 No. 1 (2024): Agribiohealth (Journal of Agriculture, Biology & Health Sciences)
Publisher : Medico Insight Innovation Initiative

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65318/agribiohealth.v1i1.2

Abstract

Breast engorgement occurs in 1 out of 8000 cases, with research reporting prevalence rates between 20-70%, while in Indonesia it reaches 37%. This condition can lead to discomfort for the mother, including symptoms like pain, breast hardness, difficulties for the baby to latch, mastitis, abscesses, and potential breastfeeding failure. Cabbage (Brassica Oleracea Var. Capitata) has been shown to alleviate breast swelling due to its sulphate content, which helps dilate capillary blood vessels, improve blood circulation, and promote the reabsorption of fluid trapped in the breast tissue. A quasi-experimental one-group pretest-posttest design was employed, involving 32 participants. Statistical analysis was conducted using the Wilcoxon test. The results revealed that, prior to treatment, most respondents (65.6%) experienced moderate pain, while 34.3% reported severe pain due to breast engorgement. Post-treatment, 75% of respondents experienced moderate pain, followed by 21.8% with mild pain, and only 3.1% reported severe pain. The Wilcoxon test indicated a p-value < α (0.05), suggesting a significant effect of cabbage leaf compresses on reducing breast pain in postpartum mothers. In conclusion, cabbage leaf compresses effectively reduce breast engorgement pain in postpartum mothers.
The Role of Parents in Providing Sex Education to Preschool Children Utami, Tri; Kurniawati, Erna Yovi; Azka, Arlina
Agribiohealth (Journal of Agriculture, Biology & Health Sciences) Vol. 1 No. 1 (2024): Agribiohealth (Journal of Agriculture, Biology & Health Sciences)
Publisher : Medico Insight Innovation Initiative

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65318/agribiohealth.v1i1.6

Abstract

Violence against women in Indonesia is dominated by cases of sexual violence. Sex education in early childhood is needed to give children an understanding of the anatomy of the human reproductive organs in a simple and understandable way. This study aims to determine the role of parents in providing sex education in early childhood or preschool. This study uses a quantitative descriptive design with a cross-sectional design. The research was conducted at Masyithoh Ngasem Nursery School on 44 children who were purposively selected. Parental role was measured using a questionnaire. The data were analysed univariately. The results showed that most of the parents (90.21%) had provided good sex education to their children. In addition to explaining the genital organs, parents must be able to give examples and teach children to tell their parents if someone else touches their genitals. Sex education in early childhood is expected to prevent child sexual abuse and other sexual crimes. Children who know will be able to avoid, refuse and tell their parents if they are confronted with conditions that are suspected to lead to sexual crimes.