Rachmah, Qonita
Departemen Gizi Kesehatan, Fakultas Kesehatan Masyarakat, Universitas Airlangga

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Journal : The Indonesian Journal of Public Health

THE EFFECT OF LOW-FIBER DIETS ON COLORECTAL CANCER INCIDENCE IN SOUTHEAST AND EAST ASIA: SYSTEMATIC REVIEW AND META-ANALYSIS Tia Eka Novianti; Qonita Rachmah; Merryana Adriani
The Indonesian Journal of Public Health Vol. 18 No. 2 (2023): THE INDONESIAN JOURNAL OF PUBLIC HEALTH
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijph.v18i2.2023.353-365

Abstract

Introduction : Colorectal cancer is a malignant tumor that grows in the colon tissue. In the Asian region, in 2018, cases and deaths from colorectal cancer are highest in East Asia (there were 736,573 cases and 325,128 of them died) and Southeast Asia (there were 95,223 cases and 52,475 of them died). Aims: Several studies have been conducted regarding the effect of a low-fiber diet and an increased risk of colorectal cancer, but it still shows mixed results. Methods: This study is an unobstrutive study with a systematic review and meta-analysis method. Data sources came from 14 primary studies with a case-control study design that met the inclusion criteria. Data analysis was performed using CMA software trial version 3.0 with a confidence level of α = 5%. Research with low-fiber diet variables shows heterogeneous variations in results so that the chosen model is random effect model. Result: The analysis states that there was a significant relationship between a low-fiber diet (CI: 0.421–0.867) and an increased risk of colorectal cancer due to the role of soluble and insoluble fiber. Lack of intake of soluble fiber can decrease insulin action and blood sugar control or the production of short-chain fatty acids, whereas insufficient intake of insoluble fiber can increase the potential for interactions between mutagens and colonic mucosa. Conclusion: The results of the study are expected to be an input for a proper diet so that there is no increase in cases of colorectal cancer.
Co-Authors Ade Lia Ramadani Adila, Yulia Agustin Asri Meidyah Agustin, Asri Meidyah Alifah Nurria Nastiti Aliffah Nurria Nastiti Andamarai, Natasya Ayu Anisa Lailatul Fitria Anisa Lailatul Fitria Arif Sabta Aji Arsa, Avilla Arum Damar Aditya Bayu Sukma Asri Meidyah Agustin Asri Meidyah Agustin Asri Meidyah Agustin Asri Meidyah Agustin Asri Meidyah Agustin Azizah Ajeng Pratiwi Azizah Ajeng Pratiwi Chusnul Fadilla Dhorta, Nandia Firsty Diah Indriani Dominikus Raditya Atmaka Erwanda Anugrah Permatasari Farapti Farapti Fatqiatul Wulandari Fermeza, Ratu Dien Prima Fitria, Anisa Lailatul Hario Megatsari Haryana, Nila Reswari Hedianti, Diah Riski Ismayani Junaida Astina Juwariyah Juwariyah Khoridah Annabila Lailatul Muniroh Lilis Sulistyorini Mahmud Aditya Rifqi Maris Mumtaza Martha Ria Wijayanti Merryana Adriani Nabiil Ikbaar Maulana Nabila Mutia Rahma Nabilla Rachmah Nabilla Rachmah Nasikhah, Aprilia Durotun Nastiti, Aliffah Nurria Nastiti, Aliffah Nurria Nor, Norfezah Md Nurdin, Amila Nurul Qomariyah Pratiwi Azizah Ajeng Pratiwi, Azizah Ajeng Purnomo, Muhammad andy Dwi Rahmani, Alinda Rasyidi, Mohammad Fahmi Ratna Kuatiningsari Rian Diana Rian Diana Rian Diana Riris Diana Rachmayanti Rochmah, Thini Nurul Roseprilla, Adamina Dinda Sabrina, Hasna Nur Salsabila Meivitama Arsanti Sarworini, Endah Sheryll Deby Regyna Shrimarti Rukmini Devy Sianturi, Olivia Simangunsong, Tiara Tivany Siti Helmyati Siti Rahayu Nadhiroh Sitti Patimah Sri Adiningsih Sri Andari, Sri Stefania Widya Setyaningtyas Susi Hidayah Tia Eka Novianti Trias Mahmudiono Triska Susila Nindya Ulya, Rufaida Adya Nur Avianti Varera, Yolanda Eggy Wigati Maria Wulandari, Fatqiatul Wuri Diah Handayani Yurike Adhela Yusryana, Eka Anisah Zaelani, Muhammad Ziddan Zeni Firginingtyas