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Formulation And Physical Properties Testing Of Lip Tint Preparations Of Akalifa Leaf Extract (Acalypha Wilkeisiana Mueill. Arg) Mayasari, Shinta; Siti Nur Maulita; Ayu Angger Putri M. Soleh; Fendy Prasetyawan; Arista Wahyu Ningsih
Jurnal EduHealth Vol. 16 No. 01 (2025): Jurnal EduHealt, Edition January - March, 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cosmetics are preparations of several ingredients for external use such as skin epidermis, hair, nails, lips, teeth and oral cavity. Lip tint is a lip coloring product that helps lips become more colorful and fresher. One of the plants that can be used as a natural dye is akalifa leaves (Acalypha wilkeisiana Müeill. Arg.). Based on research, akalifa leaves contain chemicals, namely, saponins, flavonoids, tannins, polyphenols, alkaloids. To make formulations and test the physical properties of lip tint preparations with concentrations of 10%, 13%, 16%.This research method uses a laboratory experimental design. The sample used in this research was akalifa leaf extract which was obtained by the maceration extraction method using 96% ethanol solvent. Physical property tests carried out include organoleptic tests, homogeneity tests, pH tests, irritation tests, spreadability tests, hedonic tests. The data will then be analyzed with one way ANOVA tests and LSD tests. The formulation results from concentrations of 10%, 13%, 16% which were liked by many panelists were F3. Evaluation of the physical properties of organoleptic tests on 4 lip tint preparations of akalifa leaf extract and one of them without extract (blank) has a clear color (F0), pink color (F1), red color (F2), deep dark red color (F3). The results of the irritation test at F0 – F3 showed that there was no irritation among the panelists. The parameters for protecting against irritation reactions were reviewed based on the presence of mild erythema, clear erythema, and strong erythema. The lip tint formulation with a concentration of akalifa leaf extract  16% (F3) was most preferred by the panelists. The physical properties observed include organoleptic tests, homogeneity tests, pH tests, irritation tests, spreadability tests, and liking tests, all of which show good results and are safe to use.
Artikel Riview: Profil Studi Fitokimia Dan Aktivitas Farmakologi Buah Mangga (Mangifera Indica L.) Kurrota Ayyun; Rosydah, Yeka Khafidz Ila; Atikah, Nandiyyah; Arianti, Shabrina Putri; Maulidini, Cici; Agustino, Faizal; Putri, Nadiya Kamiliya; Seran, Agustinus Alfred; S.Klau, Ivan Charles; Ningsih, Arista Wahyu
Jurnal Sains Farmasi Dan Kesehatan Vol. 1 No. 2 (2023): September - Desember
Publisher : CV. ITTC INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62379/jfkes.v1i2.346

Abstract

The mango plant (Mangifera indica L.) is a plant that is often found around. Empirically, this plant has been widely used in traditional medicine around the world, one of which is ayuverda treatment from India. Due to these many empirical functions, many studies have been conducted on the pharmacological activities of mango plants. This article discusses the pharmacological activities and phytochemical tests that have been investigated and confirmed both in vitro and in vivo with the literature review method. The results obtained show the presence of several compounds found in mango plants such as: alkaloids, flavonoids, terpenoids, saponins, tannins, phenols and steroids. Because of the compounds contained in mango plants, there are several pharmacological activities including: antioxidant activity, antidiabetic, anti-inflammatory, hepatoprotective, anti-hyperlipidemia, anti-hyperglycemia, antimicrobial, antiobesity, antifungal, antidiarrheal, and antitumor, among others.
Effectiveness of Antidiarrheal Unripe Wooden Banana (Musa paradisiaca L.) in Male Balb-C/Mice Induced with Escherichia coli Ningsih, Arista Wahyu; Rochmanti, Maftuchah; Basori, Achmad
Folia Medica Indonesiana Vol. 56 No. 3 (2020): September
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (876.182 KB) | DOI: 10.20473/fmi.v56i3.24558

Abstract

The survey results in Indonesia in 2017 showed that the diarrhea morbidity rate for all age groups was 6.897.463. In Indonesia, unripe wooden banana has been used empirically as an antidiarrheal by the people in Senduro village, Lumajang, East Java. The study aimed to prove the antidiarrheal effect of ethanol extract of unripe wooden banana (Musa paradisiaca L) in male Balb-C/mice induced by Escherichia coli bacteria.This study was a laboratory experimental study with post-test only control group design that used 40 micedivided into 8 groups, namely 1group without treatment (normal mice) and 7 groups induced by Escherichia coli(1negative controlgroup given CMC-Na, 3 groups positive controls were given Loperamid HCL 0,5 mg/kgBB, 1 mg/kgBB and 2 mg/kgBB and 3 treatment groups were given extracts 100 mg/kgBB, 200 mg/kgBB and 400 mg/kgBB). Observation of animals in this study was carried out for 4 hours. Data were analyzed of frequency of diarrhea, fecal weight and fecal consistency used Kruskal Wallis and the results showed significant differences between treatment groups (p <0.05). From the results of the Mann-Whitney test, the ethanol extract of unripe wooden banana with a dose of 100 mg/kgBB was notsignificantly different (p> 0.05) with the control group of Loperamid HCL dose of 0.5 mg/kgBB. Unripe wooden banana had been shown to have antidiarrheal activity at an extract dose of 100 mg/kg BB in terms of the parameters of fecal consistency, frequency of diarrhea, and fecal weight. The results showed that the higher the dose, the better antidiarrheal activity
Antimicrobial activity and phytochemicals compound profile of ethanol extract Moringa leaf (Moringa oleifera) compounds by FTIR Ningsih, Arista Wahyu; Safıra, Aulia Dinda; Giovano, Andre; S.Klau, Ivan Charles
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 1 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i1.1231

Abstract

Moringa plants are known in various parts of the world as a type of vegetable plant that is rich in nutrients and has multiple properties, one of which is as an antimicrobial. This research was conducted to test the antimicrobial inhibition of Moringa leaf decoction and ethanol extract against the growth of Escherichia coli and Aspergillus niger. The antimicrobial test in this study used the Disc diffusion method using various concentrations, including 25%, 50%, 75%, and 100%. There were two test samples, Moringa leaf decoction and ethanol extract using the maceration method with 96% ethanol solvent. In addition to the test group, there was also a control group, namely a positive control using chloramphenicol and ketoconazole antibiotics, negative control using aquadest as a decoction solvent, and DMSO as an extraction solvent. The ethanol extract was identified by the FTIR method. The results showed that Moringa leaf decoction and Moringa leaf ethanol extract could be used as antibacterial. Inhibition zones on Escherichia coli bacteria produced at concentrations of 25%, 50%, and 75% had a weak zone of inhibition category for both decoction and ethanol extract of Moringa leaves. Meanwhile, at a concentration of 100%, the decoction has a weak zone of inhibition and 100% ethanol extract of Moringa leaves can inhibit 8.25 mm which is included in the medium category. The inhibition zones of the fungus Aspergillus niger produced at concentrations of 25%, 50%, 75%, and 100% had no inhibition on both the decoction and ethanol extract of Moringa leaves. From the analysis of functional groups using the FTIR method, it can be predicted that in the Moringa leaf extract with methanol as solvent there are groups of phenolic compounds or flavonoids.
Optimalisasi Pemanfaatan Bunga Telang sebagai Produk Unggulan Desa Sumberwaru bersama Ibu PKK Rahmawati, Dewi; Anggrelia, Tarizza Puspa; Ambari, Yani; Ningsih, Arista Wahyu; Aristia, Bella Fevi; Klau, Ivan Charles Seran
Jurnal Abdi Masyarakat (JAM) Vol 10, No 2 (2025): JAM (Jurnal Abdi Masyarakat) - Maret 2025
Publisher : Universitas Mercu Buana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22441/jam.v10i2.30397

Abstract

In Indonesia, butterfly pea flowers are known as ornamental and medicinal plants with various benefits. Utilization of natural potential as a superior village product is a strategic step in improving community welfare and the local economy. Sumberwaru Village has superior natural resources, one of which is butterfly pea flowers (Clitoria ternatea L.). This community service aims to optimize the utilization of butterfly pea flowers (Clitoria ternatea L.) as a superior product in Sumberwaru Village through education and demonstration programs for PKK mothers. The methods used in this study were 1) implementation, community service activities began with the provision of materials related to the utilization of butterfly pea flowers, 2) evaluation, conducted by comparing the average scores before and after the test to measure the increase in participants' knowledge. The results of the activity showed that education succeeded in increasing community knowledge by 41.08%, with an average pre-test and post-test value of 51.89% and 92.97%. The evaluation results showed that the utilization of butterfly pea flowers can be a strategic step in developing village potential and increasing community participation in local economic activities.
MENTAL HEALTH COUNSELING TO IMPROVE THE ROLE OF THE FAMILY IN CARE FOR ODGJ IN SUMBERWARU VILLAGE, EAST JAVA Rahmawati, Dewi; Anjani, Soffia Dwi; Ambari, Yani; Ningsih, Arista Wahyu; Aristia, Bella Fevi; Klau, Ivan Charles Seran; Nurhidayah, Eka Putri
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 9 No. 2 (2025): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/.v9i2.2025.308-315

Abstract

The results of the 2023 Basic Health Research in East Java showed that 98.5% of severe ODGJ had received mental health services, but this achievement still did not meet the target. The imbalance between the increase in cases and the number of patients seeking treatment is a major challenge. One of the contributing factors is the lack of continuous monitoring by limited health workers. Therefore, this mental health counseling activity aims to increase the role of families in supporting the recovery of ODGJ patients through education and assistance. This activity was carried out in Sumberwaru Village for one day and involved 8 ODGJ families and 22 mothers of toddlers and the elderly. The methods used included counseling through lectures, interactive discussions, and question and answer sessions. Evaluation of success was carried out with a pre-test and post-test to measure the increase in participants' understanding before and after the activity. In addition, direct observation was carried out on family involvement in caring for patients, such as reminding them to take medication and taking them to the mental health post. The evaluation results showed an increase in participants' understanding from 69.33% in the pre-test to 90.66% in the post-test, indicating success in increasing family awareness of their role in accompanying ODGJ. In addition, families were more active in ensuring that patients received the necessary care. In conclusion, family-based counseling is effective in increasing family understanding and involvement in ODGJ care, so it can help prevent relapse and improve the patient's quality of life.
ARTIKEL REVIEW : STUDI FITOKIMIA DAN FARMAKOLOGI PISANG KEPOK (Musa paradisiaca) Khoiriyah, Siti; Triani, Rheina Febby; Putra, Achmad Ikrar Toriq Purnomo; Andini, Viola Putri; Dewi, Wulan Novita; Salim, Nadiya Difilla; Ocatviani, Siti Yunita; S.Klau, Ivan Charles; Ningsih, Arista Wahyu
BENCOOLEN JOURNAL OF PHARMACY Vol. 5 No. 1 (2025): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v5i1.38978

Abstract

Penelitian ini bertujuan untuk mengkaji senyawa fitokimia yang terkandung dalam pisang kepok (Musa paradisiaca) serta mengevaluasi potensi farmakologinya. Pisang kepok dikenal sebagai salah satu varietas pisang yang memiliki manfaat kesehatan, namun kajian mendalam terkait komponen fitokimia dan aktivitas biologisnya masih terbatas. Dalam studi ini, ekstrak pisang kepok dianalisis menggunakan berbagai metode fitokimia, seperti uji kandungan flavonoid, tanin, alkaloid, saponin, dan fenolik. Selain itu, dilakukan pengujian aktivitas farmakologi ekstrak terhadap aktivitas antioksidan dan anti-inflamasi dengan pendekatan in vitro. Hasil penelitian menunjukkan bahwa pisang kepok mengandung senyawa fitokimia yang signifikan dan memiliki potensi sebagai sumber antioksidan alami serta agen anti-inflamasi. Penemuan ini memberikan wawasan baru mengenai penggunaan pisang kepok dalam pengembangan obat herbal atau suplemen kesehatan.
Studi Fitokimia Dan Farmakologi Buah Pisang Kayu (Musa Paradisiaca L. Var. Kayu) Sebagai Antidiare Wulandari, Winda; Klau, Ivan Charles S.; Nurmalasari, Devy Artanti; Santyas, Aisyah Adellina; Zahra, Maulidya Rachma Az; Maharani, Tiara Anisa; Sofia, Armelia Idawati; Parnaen, Shawa Satria; Ningsih, Arista Wahyu
PHARMADEMICA : Jurnal Kefarmasian dan Gizi Vol 4 No 2 (2025): Oktober - Maret
Publisher : LPPM-KI - POLTEKKES PIM (Formerly AKAFARMA-AKFAR PIM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54445/pharmademica.v4i2.71

Abstract

Banana kayu is a fruit that contains phenolics. Phenolic compounds have pharmacological effects as antidiarrheal agents. Objective: This article review aims to identify the chemicals present in the banana kayu plant (Musa paradisiaca L. Var. Kayu) and examine its pharmacological effects. Method: The employed methodology is the literature search technique. Results: This journal review article examines the pharmacological activity of banana kayu, namely antidiarrheal, antibacterial, antimicrobial, antiviral, anti-inflammatory, astringent, and antioxidant properties in various portions of the banana kayu. Banana kayu comprises components including alkaloids, tannins, saponins, flavonoids, steroids, and serotonin. Conclusion: Multiple assessments indicate that the fruit of the banana kayu plant possesses diverse compounds with numerous benefits.
Ethnopharmaceutical Study of Medicinal Plants in Sumbersuko District, Lumajang Regency Seran, Ivan Charles S Klau Charles; Utami, Wahyu Putri; Ningsih, Arista Wahyu; Rahmawati, Dewi; Fevi, Bella; Ambari, Yani
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.509

Abstract

There are approximately 400 distinct ethnic groups in Indonesia (ethnic and sub-ethnic). Traditional medical practices are one example of the kinds of knowledge that have been handed down from one generation to the next in every nation, tribe, and subgroup within those nations. The people who live in the Lumajang Regency continue to have faith in the efficacy of traditional medicine. The practice of traditional medicine or shamans who treat residents around their residences in a number of districts in Lumajang, one of which is the Sumbersuko district, is evidence that this is the case. In the Sumbersuko District, there are a total of eight speakers who continue to uphold traditions related to the use of natural materials in medical practice. Interviews and questionnaires are being used as tools for the descriptive methodology that underpins this research project. According to the findings of this research, there are 37 different species of plants that are used as traditional medicine by the local community in the Sumbersuko District. These plants are categorized into 26 different families, with the Zingiberaceae family containing the most types of plants, including as many as 5 different species of plants. According to the findings of this research, the members of the community in the Sumbersuko District utilize the following plant parts: leaves, rhizomes, bulbs, fruits, skin, seeds, stems, flowers, sap, and all other plant parts. The leaf is the most commonly used component of the plant. To prepare plants for use, they are typically boiled, grated, ground, kneaded, and squeezed before being put to direct use.Keywords: consist of 3-5 words or phrases represent the focus of writing.
FORMULASI DAN UJI STABILITAS SEDIAAN CLAY MASK EKSTRAK BUNGA TELANG (Clitoria ternatea L.) DENGAN VARIASI KONSENTRASI KAOLIN DAN BENTONIT Rahmawati, Dewi; Auli, Andira; Ambari, Yani; Ningsih, Arista Wahyu; Beti Pudyastuti, Beti; Erwiyani, Agitya Resti
Jurnal Farmasi Higea Vol 17, No 2 (2025)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v17i2.735

Abstract

Pemakaian bahan alami dalam produk perawatan kulit semakin populer karena dinilai lebih aman dan ramah lingkungan. Salah satu tanaman yang berpotensi sebagai bahan aktif adalah bunga telang (Clitoria ternatea L.), yang diketahui mengandung senyawa flavonoid, alkaloid, tanin, terpenoid, dan antosianin dengan aktivitas antioksidan yang tinggi. Senyawa-senyawa ini berperan penting dalam menangkal radikal bebas yang dapat merusak sel kulit. Tujuan dari penelitian ini adalah untuk mengetahui apakah ekstrak bunga telang dapat diformulasikan menjadi sediaan clay mask yang memenuhi standar mutu fisik serta stabil selama penyimpanan. Metode yang digunakan eksperimental laboratorium. Ekstrak bunga telang diperoleh melalui maserasi dengan etanol 70% dan kemudian di formulasi menjadi sediaan clay mask dengan berbagai konsentrasi F1 (kaolin 35% : bentonite 0,5%), F2 (kaolin 30% : bentonite 1%), dan F3 (kaolin 25% : bentonite 1,5%). Parameter uji stabilitas fisik meliputi uji organoleptik, homogenitas, daya sebar, daya lekat, waktu kering, viskositas dan pH. Hasil penelitian yang diperoleh bahwa ekstrak bunga telang dapat dibuat menjadi clay mask dengan perbedaan konsentrasi basis yang digunakan. Stabilitas fisik ketiga sediaan clay mask untuk pengujian organoleptik, homogenitas, daya sebar, daya lekat, waktu kering, viskositas dan pH sudah memenuhi pesyaratan formulasi yang baik. Perbedaan konsentrasi basis sediaan clay mask didapatkan formula terbaik pada F1 (kaolin 35% : bentonite 0,5%). Perbedaan konsentrasi basis pada F1, F2, dan F3 berdampak signifikan pada hasil uji mutu fisik.
Co-Authors Achmad Basori, Achmad Acivrida Mega Charisma Agitya Resti Erwiyani Agustino, Faizal Agustinus Alfred Seran Ainul Ghurri Alvito syawal zubkhi Amarullah, Adinugraha Ambari, Yani Andini, Viola Putri Andriana, Laily Mita Anggrelia, Tarizza Puspa Anisa Rachman Anjani, Soffia Dwi Anwari, Farida Aprilia Puji Astuti Ardian, Yohanes Arianti, Shabrina Putri Aristia, Bela Fevi Aristia, Bella Fevi Atikah, Nandiyyah Auli, Andira Aulia, Andira Ayu Angger Putri M. Soleh A’Yunil Hisbiyah Battista Leki, Karol Giovani Beti Pudyastuti, Beti Brelianty Nevy Cestya Nurba'id, Anggun Rusfikadewi Charisma, Acivrida Mega Citra, Ananta DEWI RAHMAWATI Dewi, Wulan Novita Djelang Zainuddin Fickri Elis Anita Farida Elly Eka Rahmawati Elsa Saqila Elvira Silvany Zahara Ewalde Yovita Bria Farida, Elis Anita Femas Angga Saputra Fendy Prasetyawan Fevi, Bella Fina Nikmatul Wasi’ah Fitriyanti, Andira Aulia Giovano, Andre Hanin, Sisilia Nafidzah Hapsari, Fitra Nanda Dwi Helmalia Jelita Putri Hisbiyah, A'yunil Ikakiswa Imamah Febrianti Isafani, Nungki Hatit Ismatun Maulidiyah Ivan Charles S.Klau izudin, ikhsan Jihan Fahiroh Nur Arifin Klau, Irvan Charles S. Klau, Irvan Charles Seran Klau, Ivan Charles S. Klau, Ivan Charles Seran Kurrota Ayyun Lailatul, Sevi M. Ilham Fannany Maftuchah Maftuchah Magdalena Kasmin Belaon Lebuan Maghfiroh, Firda Intan Maharani, Tiara Anisa Maria Fransiska Silviani Derosari Maria Magdalena Marscha Dwi Lestari Marthy Meliana Ariyanti Jalmav Martina Kurnia Rohmah Maulidini, Cici Maulidiyah Cholifah Mayang, Tiara Sekar Meiva Shafa Herdini Miya Hartini Nur Wakhid Mohammad Fathoni Mutmainah, Rosalina Nadya Tazkiyah Tsabitah Nafilah, Zumrotin Nailah Mutiara Wahid Niken Rahmita Khairani Nisyak, Hesti Khoirotun Novita E. Winarni Nurhidayah, Eka Putri Nurmalasari, Devy Artanti Nurrosyidah, Iif Hanifa Ocatviani, Siti Yunita Oktafia Damayanti Pahri Paramita, Hanik Endah Parnaen, Shawa Satria Putra Tawakal, Muhamad Aulia Putra, Achmad Ikrar Toriq Purnomo Putri aisyha Putri, Masitah Nurwidiya Putri, Nadiya Kamiliya Regar, Ria Ressi, Monica Retno Wulan Devitri Rohmah, Atina Wahdatar Rosita, Melia Eka Rosydah, Yeka Khafidz Ila Rusdiana Tri Septiarini Ryan Satria Pranata S.Klau, Ivan Charles Safanda Tiara Fitri Safıra, Aulia Dinda Salim, Nadiya Difilla Samsiyeh, Nur Arzy Santyas, Aisyah Adellina Sari, Devi Amelia Selfya Ningrum Seran, Agustinus Alfred Seran, Ivan Charles Seran, Ivan Charles S Klau Charles Shinta Mayasari Silvi Novita Sinaga, Butet Sirojul Eilma Siti Khoiriyah Siti Nur Maulita Sofia, Armelia Idawati Triani, Rheina Febby Utami, Wahyu Putri Vira Maulidya Wahyuni, Khurin In Wardani, Eka Pramuda Winda Wulandari, Winda Windi Tri Wahyuni Yani Ambari Yasmine Eka Maulidya Zahra, Maulidya Rachma Az Zahratul Humaidah Zakkiya Sabila