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Differences in Urea And Creatinine Levels in St-Elevation Myocardial Infarction (STEMI) And Non-St-Elevation Myocardial Infarction (NSTEMI) at Dr. Doris Sylvanus Hospital Mallewa, Nurul Ilmi; Patricia, Tisha; Frethernety, Agnes; Permatasari, Silvani; Shinta, Herlina Eka
Barigas: Jurnal Riset Mahasiswa Vol. 3 No. 3 (2025): Barigas: Jurnal Riset Mahasiswa
Publisher : Fakultas Kedokteran Universitas Palangka Raya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37304/barigas.v3i3.17663

Abstract

Acute Kidney Injury (AKI) in Acute Myocardial Infarction (AMI) patients occurs due to decreased blood flow to the kidneys. Decreased blood flow caused by blockage in coronary arteries of AMI patients both in ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI) which causes reduced blood flow so the oxygen supply carried by the blood to the myocardium is reduced. Decreased oxygen supply to myocardium reduces the heart's ability to pump blood throughout the body including to kidneys. Decreased blood flow to kidneys results decreased kidney function. Laboratory examination parameters commonly used to assess kidney function are urea and creatinine. This study aims to determine the differences urea and creatinine levels in STEMI and NSTEMI patients. This research method uses analytical observation with cross-sectional approach. Data urea and creatinine levels taken from medical records using a purposive sampling technique. Samples in this study was 170 people. Data analysis using the manwhitney test and the results of comparison of urea levels in STEMI and NSTEMI patients with a p value = 0.416 and for creatinine levels with a p value = 0.756. This means that there is no significant difference between urea and creatinine levels in STEMI and NSTEMI patients.
The Effect of Bajakah Kalalawit (Uncaria gambir) Stem Extract on Spermatozoa Viability In Vitro Silvani Permatasari; Fitha Nadia Artika; Septi Handayani; Ratna Widayati; Elsa Trinovita
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.513-518

Abstract

The prevalence process impairs sperm biochemistry and function by generating high levels of Reactive Oxygen species (ROS) and damaging sperm cells. In addition, ROS imbalance leads to decreased sperm viability, mitochondrial dysfunction, and DNA damage. The administration of Bajakah Kalalawit stem extract (Uncaria gambir (W. Hunter) Roxb.) is stated to maintain sperm quality. In vitro sperm viability tests have not been widely conducted. This study aims to determine the effect of Bajakah Kalalawit stem extract (Uncaria gambir (W. Hunter) Roxb.) on sperm viability in vitro. This research is experimental research, the type of design used is posttest only with control group design. The sample was determined by consecutive sampling and the samples taken were 15. The statistical test using LSD Post-Hoc test obtained between groups there were significant differences with p <0.05. The compounds contained in the ethanol extract of Bajakah Kalalawit stem (Uncaria gambir (W. Hunter) Roxb.) are terpenoids, flavonoids, steroids, saponins and alkaloids. Viability of spermatozoa increased significantly from the concentration of 50ng/mL with a percentage of 74.13%, 100ng/mL by 83.00%, 500ng/mL by 87.60% and 1000ng/mL by 91.27%. The ethanol extract of Bajakah Kalalawit stem (Uncaria gambir (W. Hunter) Roxb.) can affect the viability of spermatozoa in vitro.
Co-Authors Agnes Frethernety Agnes Frethernety Alexandra, Francisca Diana Andreyan Cesarianto Anna Marthea Veronica Aprilliana, Riska Arini Ratnasari Arnino A Astri Widiarti ASTRID TERESA Astrid Teresa Balyas, Abi Bakring Berliani, Victoria Chandra Chandra Dea Tutut Dede Z. A Dewi Klarita Furtuna Dewi Klarita Furtuna Dhaniang, Natasya Dwi Ari Pujianto Elsa Trinovita Elsa Trinovita Ervi Audina Munthe Fadhiyatulqalbi Ahmad, Farah Fauziyah Fatmaria, Fatmaria Febrianto E. P Fitha Nadia Artika Florence Felicia Florence Felicia Fraulein Aryati Fraulein Aryati Frethernety, Agnes Furtuna, Dewi Klarita Furtuna, Dwi Klarita Galih Indra Permana Hairunnida Rahmatina Halisa, Nida Handayani, Septi Herlina Eka Shinta I Gde Eka A Idsan, Rakha Satya Indah Noniika Indria Augustina Jhon Paris Pasaribu Kahanjak, Donna Novina Krestina, Widya Lia Sasmithae Malasinta Malasinta Malinda, Okta Mallewa, Nurul Ilmi Marliah, Dinda Masaris Mery Irayanti Misbah Misbah Muhammad Aldri Muntir Guru Singa Nabila Putri Aditya Natalia Resoldes LBN Tobing Natalia Sri Martani Nawan, Nawan Ni Putu Saraswati Ni Putu W.S.W Nida Halisa Nuha, Alya Firyal Nurfianto, Sigit Oktaviannur, Zoelva Patricia, Tisha Rahmidiati Ramadhani, Ahmad Ratna Widayati Ratna Widayati Ratna Widayati Ria Eriani Rian Ka Praja Rini Fitri R Seiya, Saint Septi Handayani Septi Handayani Sherly Marselina Sitorus, Elisabeth Prihana Rotua Syamsul Arifin Syarpin Syarpin Syarpin Tangdibali, Annisa Zaskia Alexandra Tasya, Tasya Theressia Angel Lady Saragih Tisha Patricia Toemon, Agnes Immanuela Tri Widodo Vani Vrenika Widayati, Ratna Widya Krestina Yanuardi Ikhsan Yenisa Jestin Ganindyatama Ysrafil, Ysrafil