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All Journal Pharmaciana: Jurnal Kefarmasian Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Kefarmasian AKFARINDO Abdimasku : Jurnal Pengabdian Masyarakat Jurnal Farmasi Pharmaceutical And Biomedical Sciences Journal (PBSJ) Jurnal Ilmu Hukum: Alethea Pharmacy Reports Jurnal Vokasi Kesehatan Jurnal Pharmacopoeia Journal of Community Empowerment Bencoolen Journal of Pharmacy Kreativasi: Journal of Community Empowerment Pharmacon: Jurnal Farmasi Indonesia Jurnal Abdimas Bencoolen
Rahmawati, Reza
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Identification of Drug Related Problems (DRPs) Use of Antibiotics in Pediatric Pneumonia Patients at General Hospital Bengkulu City Mahardika, Halwa Balqis; Dian Handayani; Rahmawati, Reza; Yudha, Sal Prima
Pharmacon: Jurnal Farmasi Indonesia Vol. 22 No. 2 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i2.6672

Abstract

Pneumonia in pediatrics has a high mortality rate. Primary antibiotic therapy can increase antibiotic use and cause Drug Related Problems (DRPs). This study examines the treatment profile and identifies DRPs of antibiotic use in pediatric pneumonia patients at Ummi General Hospital, Bengkulu City. This study uses a cross-sectional approach method where data is collected retrospectively through patient medical records. The population includes all pediatric patients with the main disease community-acquired-pneumonia who were treated at the Ummi General Hospital, Bengkulu City during the July-December 2022 period. The sampling technique in this study was using purposive sampling. Data was analyzed univariately, and DRPs were identified using the Pharmaceutical Care Network Europe Foundation (PCNE) algorithm version 9.1 and analyzed descriptively. The treatment profile included ampicillin inj + gentamicin inj (54.7%), sultamicillin inj (15.8%), sultamicillin inj + gentamicin inj (8.4%), ampicillin inj (8.4%), gentamicin inj (7.4%), ceftriaxone inj (3.2%), and sultamicillin inj + gentamicin inj + ceftriaxone inj (2.1%). There were 367 cases in 95 patients. Cases of DRPs included overdose (27.8%), the duration of treatment is too short (22.9%), infrequent dose regimen (18.8%), adverse drug incidence (16.9%), underdose (10.1%), drugs not following the guidelines (1.9%), the duration of treatment is too long (1.1%), and therapeutic group duplication (0.5%). The study concluded that the most common treatment was ampicillin inj + gentamicin inj (54.7), with the most frequent DRPs being overdose (27.8%), the duration of treatment is too short (22.9%), infrequent dose regimen (18.8%), adverse drug incidence (16.9%), and underdose (10.1%).
Assessment of the subchronic toxicity of ethanol extract of Merdeka-leaves (Chromolaena odorata L.) on SGOT, SGPT, and histological alterations in the kidneys and liver of male rats Pertiwi, Reza; Azhar, Afra Wafiqah; Dominica, Dwi; Yudha, Salprima; Rahmawati, Reza; Putri, Yona Harianti
Pharmaciana Vol. 15 No. 3 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i3.30278

Abstract

The Merdeka plant (Chromolaena odorata L.) is known for its various pharmacological benefits, including gastroprotection, antibacterial, antihyperglycemic effects, and wound healing promotion. To ensure safe use in the community, it is important to evaluate its potential toxicity. This study examined the effects of ethanol extract of Merdeka leaf (C. odorata) on liver function by measuring the levels of serum glutamic-oxaloacetic transaminase (SGOT) and serum glutamic-pyruvate transaminase (SGPT) in male rats (Rattus norvegicus). Twenty-five male Wistar rats were split into five groups: three treatment groups that received ethanol extract at doses of 150 mg/kg BW, 300 mg/kg BW, and 600 mg/kg BW, a negative control group that received 0.5% Na CMC, and a normal control group that received no treatment. For 28 days, the extract was taken orally every day. Following surgery, liver and kidney tissues were removed for histology on day 29, and blood samples were obtained via the aorta. The findings demonstrated that rats administered 600 mg/kg BW of ethanol extract had significantly greater SGOT and SGPT levels than controls (p < 0.05), suggesting that high dose of Merdeka leaf extract may have an impact on kidney and liver functions.
Workshop Lilin Aromaterapi Sebagai Repellent dari Minyak Atsiri Daun Cengkeh dan Sereh di SMA Negeri 02 Kota Bengkulu Wulandari, Septi; Gustian, Irfan; Oktarini, Dwita; Rahmawati, Reza; Elfia, Mega; Hardiansyah, Yopan; Setianingrum, Siti Ilsah; Nurdiana, Nurdiana; Triananda, Juwita; Kurniawan, Affifa Fitri
ABDIMASKU : JURNAL PENGABDIAN MASYARAKAT Vol 9, No 1 (2026): JANUARI 2026
Publisher : LPPM UNIVERSITAS DIAN NUSWANTORO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62411/ja.v9i1.3161

Abstract

Tujuan workshop ini untuk meningkatkan pengetahuan dan soft skill para siswa/I mengenai manfaat penggunaan bahan alam yaitu minyak atsiri sebagai bahan aktif repellent dalam lilin aromaterapi  dan mengarahkan perilaku dan pola pikir ekonomi produktif metode yang digunakan Adalah pemberian quisioner sebanyak 5 pertanyaan sebelum workshop dilakukan lalu melakukan post-test seletahnya. Hasil yang didapat pada workshop ini Adalah terjadi peningkatan pemahaman siswa/siswi mengenai pemakaian minyak atsiri sebagai repellent. Semua pertanyakan yang diajukan pada saat post-test sudah terjawab lebih dari 80%. Juga membuka pola pikir siswa/siswi mengenai produk ekonomi produktif berupa hampers wisuda dengan berbagai kemasan.
Co-Authors Agus Martono Aina Fatkhil Haque, Aina Fatkhil Alawiya Simanullang, Khairatul Amanda, Savira Intan Asdim Azhar Syed Sulaiman, Syed Azhar, Afra Wafiqah Charles Banon Damaiyana, Tahnia Delia Komala Sari, Delia Komala Dian Handayani Dian Handayani Dominica, Dwi Dwita Oktiarni Elena, Felicitas Eliza, Delila Evelyne Riandini Evi Maryanti Fathiyyah Afifah Fajarriani Fernando Fernando, Fernando Firza, Bunga Al Fita Rahmawati Hardiansyah, Yopan Harianti Putri, Yona Hendri Saputra Indah Sari, Puput Tri Irfan Gustian Jayawarsa, A.A. Ketut Juniarti, Silvia Kamilla Putri, Dwi Komala Sari, Delia Kurniawan, Affifa Fitri Lestari, Feny Mahardika, Halwa Balqis Mega Elfia Muslimah, Annisa Nadia Nadia Nanda, Yogie Andika Tri Nur Khaliq, Iyas Nurdiana Nurdiana Nurhayati, Dwi Endah Okta, Fauzia Noprima Oktarini, Dwita Oktarini, Rizki Pratiwi, Reza Putri Nurlita, Septia Putri, Yona Harianti Reza Pertiwi Riandini, Evelyn Romdani, Ayu Nadiyah Permatasari Sal Prima Yudha SALPRIMA YUDHA S Salsabila, Adinda Okta Salsabila, Fazira Salsabila, Frisya Nutia Samuel Saut Martua Samosir Sari, Dwi Dominica Sari, Rose Intan Perma SEPTI WULANDARI Setianingrum, Siti Ilsah Shavitry, Ayyu Triananda, Juwita Virania, Geatika Yesika, Relin Yona Harianti Putri Yudha, Sal Prima Yudha S