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All Journal Biospecies Indonesian Journal of Urology Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Indian Journal of Forensic Medicine & Toxicology Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara AMMA : Jurnal Pengabdian Masyarakat Majority Indonesian Science Education Journal (ISEJ) JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Sutyarso
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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The SNP rs13118928, rs1828591 and rs10519717 in the HHIP Gene are not Associated on COPD Susceptibility in Male Javanese Smokers Syazili Mustofa; Sutyarso; Muhartono; Yandri; Retno Ariza Soeprihatini Soemarwoto; Hendri Busman; Wawan Abdullah Setiawan
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.17108

Abstract

Background: Hedgehog Interacting Protein (HHIP) gene polymorphisms have an association on COPDhas been carried out in Europe and Asia but in Indonesia there is still very limited study on this type andthe largest ethnic group in Indonesia is the Javanese. Objective: To analyze the association between theHHIP gene polymorphism and the incidence of COPD in male Javanese smokers in Lampung, Indonesia.Method: In a case-control study in Javanese male smokers, three single nucleotide polymorphism (SNPs)in the HHIP gene were analyzed by Sanger sequencing method. There were 110 participants in this studywhich were divided into 2 groups, such as COPD group (55 participants) and control group (55 participants).Three SNPs in the gene (rs13118928, rs1828591 and rs10519717) were selected for genotyping. Genotypedistributions were compared between patients and controls. The statistical analysis was carried out with theSPSS program with a chi-square test. Result: The genotypic frequency of the HHIP gene sequence at theSNP position rs1828591, such as AA (52.72%), GG (3.63%) and AG (43.63%) in COPD group, while inthe control group such as AA (38.18%), GG (9.09%) and GG (52.72%; p > 0.05). The genotypic frequencyof the HHIP gene sequence at the SNP position rs13118928 consisted of AA (47.27%) and AG (53.72%)in the control group, while the COPD group consisted of AA (52.72%), GG (1.81%) and AG (45.45%; p> 0.05). The genotypic frequency of the HHIP gene sequence at the SNP position rs10519717 consistedof TT (34.54%), CC (14.56%) and CT (50.90%) in COPD group, while controls group consisted of TT(23.63%), CC (16.37%) and CT (60.00%; p > 0.05). The genotypic analysis of Three SNPs in HHIP genewere observed but showed no significant difference between case and control groups. Conclusion: Singlenucleotidevariants in the HHIP gene are not associated with COPD susceptibility in Javanese male smokers.
Penyuluhan Pemberdayaan Limbah Cair Aren Untuk Pembuatan Nata de Legen di Desa Gebang, Pesawaran, Lampung ENDANG NURCAHYANI; Tundjung Tripeni Handayani; Sutyarso; Emantis Rosa; Lucy Adi Tama; R. Fadly Bayu Dwiyoga
AMMA : Jurnal Pengabdian Masyarakat Vol. 1 No. 09 (2022): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Society in general, has long known the palm tree (Arenga pinnata Merr.) as a tree that can produce materials for the craft industry. Almost all parts or products of this plant can be utilized and have economic value, however, this plant has received less attention to be developed or cultivated seriously by various parties. Most of the farmers only process the palm sugar into brown sugar and fro, while the sap water is only made for ordinary drinks. The selling price of palm sap is also very cheap, especially at harvest time the price drops sharply. Based on these reasons, it is necessary to develop new innovations in the processing of palm sap which has only been used as an ordinary drink. The new innovation is to make nira as Nata de Legen as an alternative to Nata de Coco. Through this innovation, it is hoped that the people of Gebang Village, Pesawaran, Lampung will know more about the other benefits of palm sap as a high-value food. This counseling is also expected to be able to increase public insight to utilize palm sap into products that have added value economically.
Hubungan Ketuban Pecah Dini dengan Kejadian Kala II Lama pada Ibu Bersalin di RSUD Abdul Moeloek Provinsi Lampung Tri Lamtiur Pakpahan; Ratna Dewi Puspita Sari; Sutyarso; Rodiani
MAJORITY Vol 10 No 1 (2021): MAJORITY
Publisher : Majority

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Abstract

Prolonged second-stage labor is one causes of the maternal mortality rate (MMR) in the world. The average lenght of labor in the world causes maternal mortality by 8% and in Indonesia by 9%. Maternal mortality is most often occurs during childbirth, one of the causes is the long second stage (37%) and perinatal death itself is one of the causes is asphyxia in infants (28%). The purpose of this study was to determine the relationship of Premature Ruptur of Membrane with the events of the old stage II of maternity mothers. The method used in this study uses observational analytic methods with cross sectional design. A total of 69 patients were selected by consecutive sampling technique. The date was collected from medical records of patients in the midwifery room Dr. H. Abdul Moeloek Lampung Province. The inclusion criteria of this study were mothers aged 18-40 years with term gestational age and having KPD. Patients who were accompanied by birth defects, fetal abnormalities and parturition with conditions of sectiocesarea were excluded from the study sample. The results showed that as many as 37 patients (72.6%) who experienced premature rupture of membrane at the time of the inpartu showed an old stage II event and as many as 8 patients (44.4%) patients who experienced premature rupture of membrane when not before the party showed the event of the old stage II. Based on the Chi-square test, the value of p = 0.031 (p
Size Shortening of Body Parts of Fetus Mice (Mus musculus L.) After Giving Bitter Melon Fruit Extract (Momordica charantia L.) Andriani, Silvia; Nurcahyani, Nuning; Busman, Hendri; Sutyarso; Kurniawaty, Evi; Sahroni, Mizan; Puspa, Egita Windrianatama
Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Vol. 10 No. 2 (2023)
Publisher : Department of Biology Faculty of Mathematics and Natural Sciences Universitas Lampung in collaboration with The Indonesian Association of Biology (PBI) Lampung Branch.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jbekh.v10i2.298

Abstract

Bitter melon (Momordica charantia L.) is a plant that has traditional medicinal properties. In bitter melon fruit, there are several toxic compounds, namely momordicoside K and L, which are thought to have cytotoxic properties. This study aims to determine the teratogenic effect of bitter melon fruit extract given to pregnant females on the length of the fetus' cranium and sternum. Bitter melon fruit extraction was carried out using the maceration method using 95% ethanol. By using a completely randomized design 20 male mice and 20 female mice were divided into 4 groups. Each group consisting of 5 pregnant female mice was given bitter melon extract orally starting from day 6 to day 17 of pregnancy once a day in the morning with a treatment dose of aquabidest as a control [A], [B] 22.5 mg/30 gr BW, [C] 30 mg/30 gr BW, and [D] 37.5 mg/30 gr BW. Next, the female mice were dissected, the fetus was removed and the length of the cranium and the length of the sternum were measured. The results showed that in general, the administration of bitter melon fruit extract caused a decrease in the average length of the cranium and sternum. The results of the further analysis with the Least Significant Difference (LSD) at the 5% level showed that administering doses of [B], [C], and [D] had a significant effect on reducing the length of the cranium and sternum. The most effective dose to reduce the length of the cranium and sternum of fetal mice is 37.5 mg/30 g BW
The Effect of Black Pepper (Piper nigrum L.) Extract on Morphology and number of Mice (Mus musculus L.) Spermatozoa Induced by Progestin Hormone Indriyani; Sutyarso; Busman, Hendri; Nurcahyani, Nuning; Setyaningrum, Endah
Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Vol. 11 No. 2 (2024)
Publisher : Department of Biology Faculty of Mathematics and Natural Sciences Universitas Lampung in collaboration with The Indonesian Association of Biology (PBI) Lampung Branch.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jbekh.v11i2.384

Abstract

The progestin hormone is used as male hormonal contraception. Giving progestin to normal men can  suppress libido and testicular function effectively, and reduce testosterone levels so that it can interferer with the spermatogenesis process. This study is about the effectiveness of black pepper (Piper nigrum L.) extract on morphology and number of spermatozoa in mice (Mus musculus L.)  induced by progestin. This study used a completely randomized design (CRD) which has divided into four treatment groups, each group contained 5 mice and treated according to the experimental design. Group P0 as a control (given H2O), P1 (induced by 1,25 mg progestin), P2 (induced by 1,25 mg progestin and 3.33mg/Kg BW ethanol extract of black pepper), and P3 (induced by 1,25 mg progestin and 3.33mg/Kg BW distilled water extract of black pepper). The Progestin hormone is given twice (week 1 and week 2). Black pepper extract was given daily for 35 days. Data were analyzed by one-way ANOVA and continued with the LSD test with a level of 5%. The result showed that giving of ethanol extract and distilled water extract from black pepper could improve the normal morphology and number of spermatozoa in mice after induced by progestin hormone so that fertility in men increases.
EFEK JUS TOMAT TERHADAP JUMLAH DAN MOTILITAS SPERMATOZOA TIKUS PUTIH (RATTUS NORVEGICUS) YANG DIINDUKSI GENTAMISIN Alvira Balqis Soraya; Sutyarso; Rasmi Zakiah Oktarlina; Exsa Hadibrata
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 19 No. 1 (2020): Januari 2020
Publisher : Faculty of Medicine Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (264.585 KB) | DOI: 10.30743/ibnusina.v19i1.9

Abstract

Indonesia memiliki prevalensi infertilitas sebanyak 2.647.695 dari 238 juta penduduk. Infertilitas dapat disebabkan oleh faktor eksternal seperti obat antibiotik. Gentamisin merupakan antibiotik yang dapat menginduksi stres oksidatif pada saluran reproduksi pria dan menyebabkan kerusakan spermatogenesis. Tomat memiliki banyak kandungan antioksidan salah satunya, likopen yang berpotensi menghentikan kerusakan oksidatif tersebut. Penelitian ini bertujuan untuk mengetahui jumlah dan motilitas sperma yang diinduksi gentamisin. Sampel penelitian ini adalah 30 tikus putih galur Sprague dawley jantan yang dibagi ke dalam 5 kelompok, yaitu kelompok tikus yang tidak diberi perlakuan (K1), diinduksi gentamisin 20 mg/kgbb (K2), diinduksi gentamisin 20 mg/kgbb kemudian diberi jus tomat 25% (P1), 50% (P2), dan 100% (P3). Hasil Uji One Way Anova menunjukkan tidak terdapat pengaruh pemberian jus tomat terhadap jumlah spermatozoa (p>0,05), sedangkan pada motilitas terdapat pengaruh yang signifikan (P=0,00). Hasil uji Post Hoc antar kelompok kontrol dan perlakuan terdapat perbedaan signifikan (p<0,05), sehingga diperoleh kesimpulan bahwa pemberian Jus tomat 50% dan 100% dapat mencegah penurunan motilitas spermatozoa tetapi tidak memiliki efek yang nyata pada jumlah spermatozoa.
EFFECT OF RED GINGER (Zingiber officinale Rosc. Var Rubrum) ETHANOL EXTRACT OR SILDENAFIL IN LIBIDO: A COMPARATIVE STUDY USING MALE WHITE RATS (Rattus norvegicus) MODEL WITH DIABETES MELLITUS Hadibrata, Exsa; Sutyarso; Busman, Hendri; Ramdini, Dwi Aulia
Indonesian Journal of Urology Vol 32 No 3 (2025)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v32i3.949

Abstract

Objective: To compare the effect of red ginger ethanol extract and Sildenafil on increasing the libido of diabetic rat models and determine the dose that significantly affects the increase in libido of diabetic rat models. Materials & Methods: This study is an experimental was conducted on 30 male Sprague dawley white rats divided into 6 groups, namely normal control group, negative control group, sildenafil positive control group, 200 mg ginger group, 400 mg ginger group and 600 mg ginger groupstudy consisting of test animal groups: normal control group; negative control; positive control with sildenafil administration, and treatment groups consisting of: dose I (200mg/kgBB); dose II (400mg/kgBB) and, dose III (600mg/kgBB). All groups except the normal control received alloxan induction at the initial stage of testing. The effect of increasing the libido of rats is seen from sexual activity including: latency of copulation, latency of riding (climbing) and frequency of riding. Results: The results of this study indicate that the administration of red ginger ethanol extract at a dose of 400mg/kgBB or 600mg/kgBB has the same potential as sildenafil in increasing the libido of diabetic rat models. Conclusion: The administration of red ginger ethanol extract at a dose of 400mg/kgBB or 600mg/kgBB has the same potential as sildenafil in increasing the libido of diabetic rat models. Keywords: Red ginger, libido, diabetic rat models.
Prevalence and Patterns of Pneumonia in Histopathology of Lungs from Qurban Cattle (Bos spp.) in Lampung, Indonesia (2019): A Laboratory-Based Survey Nursafitri, Umy; Sutyarso; Susanto, Gregorius Nurgroho; Widiastuti, Endang Linirin
ISEJ : Indonesian Science Education Journal Vol. 5 No. 1 (2024): January
Publisher : Yayasan Darussalam Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62159/isej.v5i1.1752

Abstract

Pneumonia in cattle compromises welfare and carcass value, yet abattoir-based histopathology evidence from Indonesia’s qurban context remains scarce. To estimate the prevalence of pneumonia and characterize lesion patterns in lungs from qurban cattle processed in Lampung Province (2019). A cross-sectional, laboratory study analyzed 20 bovine lungs collected opportunistically from four districts (Bandar Lampung, Lampung Timur, Pringsewu, Metro). Representative tissues were fixed in 10% neutral buffered formalin, paraffin-embedded, sectioned at 4–5 µm, and stained with hematoxylin–eosin; bright-field microscopy (≈40×–400×) classified lesions a priori as interstitial pneumonia, bronchopneumonia, or aspiration-consistent pneumonia, and annotated severity (mild/moderate), temporality (acute/chronic), and distribution (focal/multifocal). Analyses were descriptive. 13/20 (65%) lungs met histological criteria for pneumonia, while 7/20 were normal. Interstitial cases showed alveolar-septal thickening, congestion/hemorrhage, and alveolar edema; bronchopneumonia was airway-centered with peribronchiolar cuffing and suppurative/fibrinosuppurative exudates; aspiration-consistent lesions exhibited focal/multifocal cranioventral involvement with foreign particulate material and neutrophilic exudates, occasionally with multinucleated giant cells. Most lesions were mild–moderate and predominantly acute. The profile indicates a multifactorial aetiology in which upstream infectious processes and perimortem handling both contribute, underscoring the added value of histopathology over gross inspection alone. Findings support immediate refinement of slaughter procedures (restraint, incision sequence, head positioning) to reduce aspiration risk; routine integration of histopathology paired with culture/PCR into abattoir surveillance for actionable supplier feedback; and periodic, micrograph-based auditing and training to strengthen food safety, animal welfare, and biosecurity.
Pelatihan Budidaya Jamur Tiram Untuk Peningkatan Pendapatan Petani di Desa Bandar Sari, Padang Ratu, Lampung Tengah NURCAHYANI, ENDANG; Yulianty; Sutyarso
AMMA : Jurnal Pengabdian Masyarakat Vol. 1 No. 06 (2022): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Oyster mushrooms (Pleurotus spp.) are types of mushrooms that can be consumed by humans. People generally cultivate mushrooms with white fruiting bodies, so they are called white oyster mushrooms. The cultivation of oyster mushrooms is the same as the cultivation of other edible mushrooms. White oyster mushroom (Pleurotus ostreatus) is often found in traditional markets and supermarkets. The market demand for white oyster mushrooms is still very large, but the production of white oyster mushrooms is still very low. Along with the increasing popularity of oyster mushrooms in the community, causing consumer demand and the market for oyster mushrooms to continue to increase, therefore to meet these needs it is necessary to cultivate white oyster mushrooms more optimally. Based on observations in Bandar Sari Village, Central Lampung, the community has not done much white oyster mushroom cultivation, so this community service activity needs to be carried out by conducting training on oyster mushroom cultivation for the local community, it is hoped that this training can serve as an economic source for the community in the future. This training activity was held on September 17, 2021 in Bandar Sari Village, Central Lampung, aiming to provide knowledge about the types of oyster mushrooms and their benefits, oyster mushroom cultivation, and oyster mushroom processing. This activity is expected to provide skills in oyster mushroom cultivation and processing for the people of Bandar Sari Village. The results of the activity showed that people who participated in the training had increased knowledge about the types of oyster mushrooms and their benefits, oyster mushroom cultivation, and oyster mushroom processing. Keywords: Bandar Sari, Cultivation, Oyster mushrooms
KARAKTERISTIK DAN POLA SEBARAN PHYTOTELMATA SEBAGAI TEMPAT PERINDUKAN ALAMI NYAMUK DI KEBUN RAYA LIWA LAMPUNG BARAT Sitinjak, Mentoria Alviani; Rosa, Emantis; Agustrina, Rochmah; Sutyarso
Biospecies Vol. 13 No. 2 (2020): Juli 2020
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v13i2.9540

Abstract

Liwa Botanical Garden (KRL) is an ex-situ plant conservation area which has a large collection of plants. Therefore, there will be many types of plants in KRL that have phytotelmata. Phytotelmata is a plant in which the organs can hold water and is used by various organisms including mosquitoes as natural breeding grounds. The aim of this study was to determine the phytotelmata characteristics and phytotelmata distribution patterns in the Liwa Botanical Garden, West Lampung. This research was carried out in November 2019 - January 2020 at the Liwa Botanical Garden and the University of Lampung Botanical Gardens. The study was conducted descriptively with a survey method approach. The data obtained is displayed in tables and figures. The results showed that there were 7 types of phytotelmata in the Liwa Botanical Garden namely phytothelmata in the plants of Nepenthes mirabilis, Cyathea coopei, Bambusa sp. Areca catechu, Musa sp. Colocasia gigantea, and Crynum asiaticum with 2 phytotelmata distribution patterns: in groups with IP values ranging from 0.813-1,194 and uniform distribution patterns with IP values of -2.08.Keywords: Phytotelmata, Natural Breeding Ground, Kebun Raya Liwa.
Co-Authors Alvira Balqis Soraya Andriani, Silvia Balqis, Gasela Zalianti Bayu Anggileo Pramesona Betta Kurniawan, Betta Emantis Rosa Endah Setyaningrum, Endah Endang Nurcahyani Exsa Hadibrata Fithria Mumtazah, Dzul Giska Tri Putri Hadibrata, Exsa Hendri Busman Hendri Busman Indriyani Julian Khairun Nisa Kurniawaty, Evi Lucy Adi Tama Muhartono Nuning Nurcahyani Nur Azizah Nursafitri, Umy Nurul Isnaini Puspa, Egita Windrianatama R. Fadly Bayu Dwiyoga Ramdini, Dwi Aulia Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Ratna, Maya Ganda Retno Ariza Soeprihatini Soemarwoto Risal Wintoko Risal Wintoko Rochmah Agustrina Rodiani Rosa, Emantis Sahroni, Mizan Shinta Nareswari, Shinta Sitinjak, Mentoria Alviani Suharmanto suharmanto, suharmantoarman Susanto, Gregorius Nurgroho Susianti Syazili Mustofa Tri Lamtiur Pakpahan Tundjung Tripeni Handayani Wawan Abdullah Setiawan Widiastuti, Endang Linirin Yandri Yulianty