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The Effect of Nigella Sativa L. Extract on Blood Glucose Levels in Alloxan-Induced Hyperglycemic Mus musculus Khoirunnisa, Nur; Makmun, Armanto; Surdam, Zulfiyah; Nur, Muhammad Jabal; Ardiansar, Abdul Mubdi; Zulfahmidah, Zulfahmidah
Journal La Medihealtico Vol. 6 No. 3 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i3.2055

Abstract

Hyperglycemia is one of the conditions of increasing blood glucose levels. There are various treatment options in patients with hyperglycemia, one of which is non-drug therapy with traditional medicine. A traditional medicinal plant with various benefits, namely black cumin which is known to have a variety of ingredients that can lower blood glucose levels. Knowing the effect of black cumin extract on blood glucose levels in mice with alloxane-induced hyperglycemia. The research design used was a pre and post test with control group design with a total sample of 27 mice divided into 3 groups where each group consisted of 9 heads. Group 1 is the control group while group 2 and group 3 will be treated respectively. The analysis was carried out with a paired sample t-test to see the differences between each group before and after treatment. The results of the study on the average blood glucose levels before treatment and after the administration of black cumin treatment there were changes in each group obtained a significance value of 0.000 at both doses of black cumin extract. Based on the results obtained, it is known that black cumin extract can reduce blood glucose levels where the greater the dose is directly proportional to the decrease in blood glucose levels.
Characteristics of Inguinal Hernia Patients at Massenrempulu Hospital for the Period of 2023 S, Fatma Dilla; Gani, Azis Beru; Zulfahmidah, Zulfahmidah; Purnamasari, Reeny; Mubarak, Andi Firman
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 3 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i3.1682

Abstract

Background: Hernia is a condition that can occur at all ages, characterized by a lump that appears and disappears. Inguinal hernia is the most common type, with lateral inguinal hernia accounting for 50%, medial 25%, and femoral 15%. About 15% of adults suffer from inguinal hernia, with prevalence increasing from 5–8% at ages 25–40 years to 45% at age 75. Hernia repair remains the most effective general surgical procedure. Objective: To determine the characteristics of inguinal hernia patients at Massenrempulu Hospital in 2023 based on age, occupation, classification, and body mass index (BMI). Methods: This study used a descriptive method with an observational design. Data were analyzed by frequency distribution according to research variables. Results: Inguinal hernia was more common in patients aged >66 years (45.9%), in heavy work occupations (70.3%), and classified predominantly as indirect/lateral inguinal hernia (94.6%). Based on BMI, most patients were in the overweight category (54.1%). Conclusion: At Massenrempulu Hospital in 2023, inguinal hernia was mostly found in patients aged >66 years, engaged in heavy work, with indirect/lateral classification, and overweight BMI
ANALISIS PENGETAHUAN MENGENAI INFORMED CONSENT PADA PASIEN SEBELUM OPERASI DI RS IBNU SINA Al-Azhariyah, Nurul Fadhilah; Amir, Suliati P.; Zulfahmidah, Zulfahmidah; Rijal, Syamsu; Arifuddin, Andi Tenri Sanna
Jambura Journal of Health Sciences and Research Vol 7, No 4 (2025): OKTOBER: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v7i4.30844

Abstract

Pelayanan kesehatan yang berkualitas adalah hak asasi setiap individu, yang diatur oleh undang-undang di Indonesia, dengan informed consent menjadi elemen kunci dalam praktik medis, terutama dalam prosedur bedah. Kebaharuan penelitian ini terletak pada fokus pada pemahaman pasien di Rumah Sakit Ibnu Sina, serta faktor-faktor yang memengaruhi pemahaman tersebut, yang belum banyak diteliti di Indonesia. Penelitian ini bertujuan untuk mengevaluasi pemahaman pasien mengenai informed consent sebelum operasi di Rumah Sakit Ibnu Sina, Makassar. Metode yang digunakan adalah desain deskriptif analitik dengan pendekatan cross-sectional. Data dikumpulkan melalui kuesioner yang mengukur tingkat pengetahuan pasien mengenai diagnosis, prosedur, risiko, alternatif tindakan, dan prognosis. Hasil penelitian menunjukkan bahwa 19,05% pasien memiliki pengetahuan baik mengenai informed consent, sementara sebagian besar (46,43%) memiliki pengetahuan cukup. Tantangan utama yang ditemukan adalah keterbatasan waktu dan komunikasi yang kurang efektif. Kesimpulannya, pemahaman pasien mengenai informed consent di Rumah Sakit Ibnu Sina tergolong baik, namun masih perlu ditingkatkan lagi. Penelitian lebih lanjut disarankan untuk mengevaluasi dampak jangka panjang pemahaman ini terhadap hasil perawatan pasien dan kepuasan pasca-operasi.
Analysis of Determinant Factors of The Bed Occupancy Rate of Ar-Rahman and Al-Ikhlas Inpatients at IBNU SINA YW UMI Hospital, 2023 Mutiara, Mutiara; Nurelly, Nurelly; Ningsi, Iin Widya; Murfat, Zulfitriani; Zulfahmidah, Zulfahmidah
Jurnal Biologi Tropis Vol. 24 No. 1 (2024): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1.6655

Abstract

Hospitals are required to provide the best and highest quality services so that more and more patients will be comfortable and satisfied when going to the hospital for treatment. This study aims to analyze the determinants of the BOR value of Ibnu Sina YW UMI Hospital. The type of research is quantitative research, descriptive analysis using a cross sectional method, and the research sample was 27 people. Data were analyzed using univariate analysis to describe the characteristics of each research variable. The research results found that the BOR (Bed Occupancy Rate) value for Ar-Rahman and Al-Ikhlas inpatient care at Ibnu Sina YW UMI Hospital was efficient according to standards. The hospital service that influences the inpatient BOR value is satisfaction with the nutritional food menu provided. Hospital facilities that influence inpatient BOR values are satisfaction with radiology facilities. The general perception of patients that influences the inpatient BOR value is a feeling of great satisfaction with fast service. It is hoped that this research can help determine the factors determining the Bed Occupancy Rate (BOR) value of Ar-Rahman and Al-Ikhlas Inpatients at Ibnu Sina YW UMI Hospital.
Tingkat Pengetahuan Masyarakat Tentang Stroke di Dusun Tamala’ba DesaPunaga Kec. Mangarabombang Kab. Takalar Tahun 2023 Haslinda, Haslinda; Arifin, Arina Fathiyyah; Muchsin, Achmad Harun; Rachman, Erwin; Zulfahmidah, Zulfahmidah
Wal'afiat Hospital Journal Vol 4 No 1 (2023): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v4i1.100

Abstract

Stroke merupakan penyakit serebrovaskuler yang menjadi penyebab kematian ketiga di dunia, khususnya negara berkembang setelah penyakit jantung koroner dan kanker. Untuk mengetahui tingkat pengetahuan masyarakat tentang stroke di Dusun Tamala’ba Desa Punaga Kec. Mangarabombang Kab. Takalar tahun 2023. Jenis penelitian yang dilakukan adalah penelitian deskriptif dengan metode cross-sectional. Analisis data menggunakan uji statistic Chi-Square. Sampel dalam penelitian ini sebanyak 110 orang masyarakat Dusun Tamala’ba Desa Punaga Kec. Mangarabombang Kab. Takalar dengan pengambilan sampel menggunakan teknik simple random sampling. Didapatkan responden dengan tingkat pengetahuan baik berdasarkan usia sebanyak 18 orang, pengetahuan cukup 47 orang, pengetahuan rendah 15 orang. Responden dengan tingkat pengetahuan baik berdasarkan Pendidikan sebanyak 18 orang, pengetahuan cukup 47 orang, pengetahuan rendah 45 orang. Responden dengan tingka pengetahuan baik berdasarkan pekerjaan sebanyak 18 orang, pengetahuan cukup 47 orang, pengetahuan rendah 45 orang. Terdapat hubungan yang signifikan antara tingkat pengetahuan penyakit stroke berdasarkan pendidikan (p kurang dari 0,05) dan tidak terdapat hubungan yang signifikan antara tingkat pengetahuan penyakit stroke berdasarkan usia dan pekerjaan (p lebih dari 0,05).
Mekanisme Molekuler Muscle Disuse Atrophy Zulfahmidah, Zulfahmidah; Safei, Imran
Wal'afiat Hospital Journal Vol 4 No 1 (2023): Wal'afiat Hospital Journal
Publisher : Rumah Sakit Ibnu Sina, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/whj.v4i1.102

Abstract

Kehilangan massa otot rangka sering terjadi sebagai respons terhadap imobilisasi sendi dan tirah baring, serta diinduksi oleh ketidak aktifan dari otot tersebut. Atrofi yang diinduksi oleh kurangnya aktivitas akan mempengaruhi setiap individu dalam hidupnya, dan dapat melemahkan terutama pada orang tua. Saat ini tidak ada terapi yang baik untuk mengobati disuse atrofi otot dapat disebabkan karena kurangnya pemahaman tentang mekanisme seluler dan molekuler yang bertanggung jawab untuk induksi dan pemeliharaan atrofi otot. Di dalam review ini akan dibahas mekanisme molekuler yang terlibat pada atropi otot disuse
The Effects of Olive Oil (Olea Europaea L.) on Cathallase Enzyme Levels in White Rats (Rattus Norvegicus) Wistar Strain of Obese Male Salmalia, Raisya Zahra; Gayatri, Sri Wahyuni; Zulfahmidah, Zulfahmidah; Syamsu, Rachmat Faisal; Rasfayanah, Rasfayanah
Formosa Journal of Science and Technology Vol. 3 No. 8 (2024): August 2024
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/fjst.v3i8.11023

Abstract

Obesity is a condition of the body resulting from excessive fat accumulation which leads to health problems. The increase in fat metabolism affects increased production of free radicals in the circulation and in adipocyte cells. Free radicals that increase in the body are not in line with antioxidant enzymes, causing a condition called oxidative stress. The body's defense mechanism against free radicals is the synthesis of antioxidants. When there is a decrease in the activity of endogenous antioxidants such as the catalase enzyme, it provides a strong indication of oxidative stress. The presence of polyphenols and monounsaturated fatty acids in olive oil is useful for preventing chronic damage that causes oxidative stress. The catalase enzyme can be used as a parameter for an uncontrolled increase in ROS (Reactive Oxygen Species) or disruption of the function of the antioxidant defense system. To determine changes in levels of the catalase enzyme in an obese male Wistar strain white rat (Rattus norvegicus) animal model that was given olive oil. This research used a true experimental laboratory with a pre- post test design. The results of the study were significant changes in catalase enzyme levels in the olive oil intervention group (p-value 0.003<0.05) on day 14 and day 28 with (p-value 0.002<0.05 and 0.005<0.05). In the group given olive oil, the effect on the level of catalase enzyme was most significant on day 28 (p-value 0.002<0.05).
Karakteristik Gejala Klinis Dan Histopatologis Pasien Kanker Serviks Di RS Ibnu Sina YW-UMI Makassar Zul-ayman, Ahmad Emil; Gayatri, Sri Wahyuni; Zulfahmidah, Zulfahmidah; Rijal, Syamsu; Amalia, Rizki
Innovative: Journal Of Social Science Research Vol. 4 No. 6 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i6.16981

Abstract

Latar Belakang: Kanker serviks adalah jenis kanker yang tumbuh di leher rahim. WHO 2020 memperkirakan sebanyak 604.000 kasus baru dan 342.000 kematian disebabkan oleh kanker serviks. Menurut The Global Cancer Observatory 2020, kasus kanker serviks di Indonesia meningkat berjumlah 36,633 (17,2%) dengan kematian sejumlah 234.511. Jumlah penderita kanker serviks di Sulawesi Selatan mencapai 536 di tahun 2017. Tujuan: Untuk mengetahui karakteristik gejala klinis dan histopatologis pasien kanker serviks di RS Ibnu Sina YW-UMI Makassar. Metode: Penelitian ini merupakan penelitian deskriptif kuantitatif dengan sumber data sekunder rekam medis dari RS Ibnu Sina YW-UMI Makassar periode 2022-2023. Hasil dan kesimpulan: Tipe sel kanker serviks terbanyak di RS Ibnu Sina YW-UMI tahun 2022-2023 adalah Squamous Cell Carsinoma (79.1%). Kelompok usia pasien penderita kanker serviks terbanyak adalah usia 36-45 tahun (35.4%). Gejala kanker serviks terbanyak adalah nyeri perut bagian bawah (44.8%). Terapi kanker serviks paling sering diberikan adalah terapi medikamentosa (47.9%). Stadium kanker serviks terbanyak adalah stadium IIB (39.6%). Kata kunci: Gejala klinis, histopatologis, Kanker serviks, RS Ibnu Sina-YW UMI.