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Uji Aktivitas Antioksidan Dari Kulit Buah Naga Merah (Hylocereus Polyrhizus) Siti Puspitasari; Yulistia Budianti Soemarie; Aris Fadillah
Journal Scientific of Mandalika (JSM) e-ISSN 2745-5955 | p-ISSN 2809-0543 Vol. 6 No. 4 (2025)
Publisher : Institut Penelitian dan Pengembangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/10.36312/vol6iss4pp1061-1072

Abstract

Antioxidants are substances or compounds that have the ability to slow or delay, or even prevent, free radical reactions. Red dragon fruit skin has benefits as a source of antioxidants. This study aims to determine the antioxidant activity of ethanol extract, n-hexane fraction, ethyl acetate fraction and water fraction of red dragon fruit peel. The sample used in this research was the skin of red dragon fruit (Hylocereus polyrhizus) which was macerated with 70% ethanol and then fractionated using different solvents. Antioxidant activity testing was carried out using the DPPH method. The research results were shown by the IC50 value of the ethanol extract of 78.674 ± 19.618 µg/ml, the n-hexane fraction 129.942 ± 12.291 µg/ml, the ethyl acetate fraction 64.681 ± 19.820 µg/ml and the water fraction 73.038 ± 4.077 µg/ml. Based on the IC50 value obtained, the ethyl acetate fraction of red dragon fruit peel (Hylocereus polyrhizus) has the highest antioxidant activity.
The Influence of Prices, Income, E-Cigarettes, and Social Environments on Cigarette Consumption Behavior of Teenagers Fadillah, Aris; Asna Prestianawati, Silvi
Journal of Development Economic and Social Studies Vol. 4 No. 4 (2025)
Publisher : Fakultas Ekonomi dan Bisnis Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/jdess.2025.04.4.03

Abstract

This study aims to analyze the influence of cigarette price increases, income, e-cigarettes, and social environment on the smoking behavior of teenage smokers of machine-made clove cigarettes (SKM). The background of this research is driven by the high rate of cigarette consumption among teenagers, despite the continuous increase in cigarette prices and the emergence of alternative products such as e-cigarettes. This research uses a quantitative method with a survey approach involving active teenage smokers as respondents. The sampling technique used is purposive sampling, and the data were analyzed using multiple linear regression with SPSS software. The results show that variables cigarette price, income, e-cigarettes, and social environment also has a significant influence. These findings indicate that teenage smoking behavior is influenced not only by economic factors but also by social factors and the availability of substitute products.
UPAYA PEMBERDAYAAN MASYARAKAT DALAM PEMANFAATAN LIMBAH ECENG GONDOK SEBAGAI SPRAY LUKA Juwita Ramadhani; Hasniah Hasniah; Dewi Rosaria; Aris Fadillah; Karina Erlianti; Muhammad Fauzi; M. Hasan Andryanto; Lia Mardiana
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 5 (2025): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i5.34501

Abstract

Abstrak: Permasalahan limbah eceng gondok yang melimpah di Desa Sungai Arfat mendorong perlunya inovasi pemanfaatan agar memiliki nilai tambah ekonomi. Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan dan keterampilan masyarakat dalam mengolah eceng gondok menjadi produk kesehatan bernilai jual serta memperkenalkan strategi promosi digital. Metode yang digunakan meliputi sosialisasi potensi eceng gondok, penyuluhan mengenai urgensi pengelolaan limbah, serta workshop pembuatan spray luka berbasis eceng gondok. Kegiatan diikuti oleh 29 anggota PKK Desa Sungai Arfat dengan pendampingan langsung dari tim pelatih, sedangkan evaluasi dilakukan melalui angket pemahaman. Evaluasi dilakukan melalui pretest dan postest, dengan indikator keberhasilan berupa peningkatan pengetahuan dan pemahaman peserta. Hasil menunjukkan rata-rata nilai pretest 51,03 meningkat menjadi 97,93 pada postest dengan kenaikan rata-rata 46,90 atau 149,71%. Kegiatan ini tidak hanya meningkatkan hardskill masyarakat dalam produksi, tetapi juga membuka peluang pengembangan UMKM berbasis eceng gondok yang berorientasi pada peningkatan ekonomi lokal secara berkelanjutan.Abstract: The problem of abundant water hyacinth waste in Sungai Arfat Village has prompted the need for innovative utilization to add economic value. This community service activity aims to increase the knowledge and skills of the community in processing water hyacinth into marketable health products and introducing digital promotion strategies. The methods used included socialization of the potential of water hyacinth, counseling on the urgency of waste management, and workshops on making water hyacinth-based wound sprays. The activity was attended by 29 members of the Sungai Arfat Village PKK with direct assistance from the training team, while the evaluation was conducted through a comprehension questionnaire. The evaluation was conducted through pre-tests and post-tests, with the success indicators being an increase in the participants' knowledge and understanding. The results showed that the average pretest score of 51.03 increased to 97.93 in the posttest, with an average increase of 46.90 or 149.71%. This activity not only improved the community's hard skills in production but also opened up opportunities for the development of water hyacinth-based MSMEs oriented towards sustainable local economic improvement.  
Gambaran Pola Peresepan Dan Rasionalitas Terapi Pada Pasien Hipertensi Di Puskesmas Banjarbaru Selatan Periode Januari-Juni 2023 Indrawan, Dede; Yulistia Budianti; Aris Fadillah
Jurnal Pelayanan Kefarmasian dan Sains Vol 6 No 1 (2025): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v6i1.740

Abstract

Background:  Rational drug prescribing must follow a logical decision-making process starting from the collection of patient data through anamnesis, physical examination, laboratory tests, or other supporting examinations. The rational use of drugs in hypertension patients is very important to ensure cost-effectiveness, prescription accuracy, and drug use, as well as to improve the quality of healthcare services by evaluating indications, patients, drugs, and appropriate dosages. Objective: This study aims to understand the pattern of prescription and the rationality of therapy in hypertension patients at the Banjarbaru Selatan Health Center during the period of January - June 2023. Methods: This descriptive study uses a retrospective approach with the collection of secondary data from medical records, including age, gender, diagnosis, type of medication, medication class, medication category, indication, usage instructions, and dosage for hypertension patients over a period of 10 days. Results: The prescription pattern for patients based on drug class and type is the Calcium Channel Blockers (CCB) class and the amlodipine type at 95.7%. All hypertension patients received single antihypertensive drug therapy at 100%. Based on the usage rules and drug dosage, the type of drug amlodipine 1x1 was 51.60%. The rationality of antihypertensive therapy in the rational category was 98.39%, including 100% correct patients, 100% correct indication, 100% correct drug, 98.39% correct dosage, and 98.39% correct administration interval. Conclusion: The pattern of prescriptions based on drug class and type of drug used is the Calcium Channel Blockers (CCB) class and the type of drug amlodipine at 95.7%, and the depiction of the rationality of hypertension treatment therapy with a rationality of 98.39% at the Banjarbaru Selatan Health Center for the period January-June 2023.
PRAKTIK PEMBUATAN SABUN BERBAHAN DASAR ALAMI DI PONDOK PESANTREN Fadillah, Aris; Mardiana, Lia; Hasniah, Hasniah; Ramadhani, Juwita; Su'aida, Nily; Fauzi, Muhammad; Erlianti, Karina
JMM (Jurnal Masyarakat Mandiri) Vol 8, No 5 (2024): Oktober
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v8i5.26075

Abstract

Abstrak: Pada perkembangannya, kurikulum pada pesantren harus dapat menyiapkan santri untuk bisa berkiprah dan hidup di masyarakat, salah satunya adalah dengan melakukan wirausaha. Pengabdian ini bertujuan meningkatkan pengetahuan dan keterampilan santri dalam pembuatan sabun berbasis ekstrak bahan alam, serta membuka peluang wirausaha. Mitra kegiatan adalah 76 santri putri tingkat menengah atas kelas XII. Metode yang digunakan meliputi penyuluhan, pelatihan praktik, dan evaluasi. Hasil pengabdian menunjukkan peningkatan pengetahuan siswa, dengan kenaikan nilai rata-rata dari 70,5 menjadi 95,61 (peningkatan nilai 25,11%). Evaluasi dengan metode kuis menunjukkan bahwa peserta dapat menerima materi dengan baik.. Kegiatan ini meningkatkan soft skill dan hard skill santri dalam produksi sabun berbahan alami.Abstract: In its development, the curriculum of Islamic boarding schools must be able to prepare the students to take part and live in society, one of which is through entrepreneurship. This program aims to increase student’s knowledge and skills in making natura based soap, and to inspire them on entrepreneurship ideas. Seventy-six high-school students participated. The methods used were lecturing, practical training, and evaluation. The results showed a significant increase in students' knowledge, with an increase in the average score from 70.5 to 95.61 point (increased by 25,11%). Evaluation through quiz method shows that the information was well received by participants. This program improves student’s soft skills and hard skills in the production of natural based soap.
EVALUASI RASIONALITAS PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA RAWAT INAP DI RSUD ULIN BANJARMASIN PERIODE JANUARI-JUNI 2024 Fadila, Ananda; Ramadhani, Juwita; Fadillah, Aris
Jurnal Kesehatan Tambusai Vol. 7 No. 1 (2026): MARET 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v7i1.53426

Abstract

Penggunaan rasional antibiotik merupakan langkah penting dalam pencegahan peningkatan resistensi terhadap antibiotik, khususnya di kalangan pasien pneumonia yang sedang rawat inap. Penelitian ini bertujuan untuk meninjau rasionalitas dalam penerapan antibiotik, yang diharapkan mampu memberikan wawasan terkait tingkat ketaatan pada pedoman penggunaan antibiotik. Metode penelitian ini bersifat deskriptif observasional dikerjakan melalui pendekatan retrospektif, dimana pengambilan data dilakukan dari rekama medis pasien pneumonia yang mengalami rawat inap pada bulan Januari-Juni tahun 2024 dan dievaluasi dengan menggunakan metode Gyssens. Teknik analisis data dideskripsikan menggunakan excel. Penelitian ini merupakan studi deskriptif observasional dengan pendekatan retrospektif melalui penelusuran data rekam medis pasien pneumonia yang memenuhi kriteria inklusi. Evaluasi rasionalitas dilakukan berdasarkan kategori Gyssens yang meliputi ketepatan indikasi, pemilihan obat, dosis, interval, rute pemberian, serta durasi terapi. Data dianalisis secara deskriptif menggunakan Microsoft Excel. Hasil diperolah Secara umum penggunaan antibiotik yang digunakan dinilai rasional sebanyak 81 (85,26%). Temuan ini menunjukkan bahwa sebagian besar penggunaan antibiotik telah sesuai dengan pedoman terapi yang berlaku, namun tetap diperlukan upaya monitoring dan evaluasi berkelanjutan untuk meningkatkan kualitas pelayanan dan mencegah resistensi antibiotik di masa mendatang.
GREEN EXTRACTION PADA DAUN MURBEI DENGAN TWEEN 20, TWEEN 80, SPAN 20, DAN SPAN 80 SERTA PENGUJIAN AKTIVITAS ANTIOKSIDAN DAN INHIBISI ENZIM TIROSINASE Hasniah Hasniah; Atikah Isma Rahmi; Karina Erlianti; Juwita Ramadhani; Muhammad Fauzi; Aris Fadillah
Jurnal Farmasi Islam Kalimantan Vol 1, No 1 (2024): Eksplorasi Kefarmasian Komprehensif: Pendekatan In Silico, Teknologi Sediaan Ala
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jfik.v1i1.15395

Abstract

Murbei (Morus alba L.) mengandung senyawa aktif yang meliputi golongan fenolik, flavonoid seperti rutin, kuersetin, asam galat dan asam klorogenik sebagai antioksidan yang dapat mengantisipasi oksidasi kulit oleh radiasi sinar UV dan sebagai penghambat tirosinase. Penelitian ini bertujuan untuk menerapkan Green Extraction pada daun murbei menggunakan alternatif pelarut pengganti pelarut organik dengan metode Microwave Assisted Extraction (MAE) serta uji daya peredaman radikal bebas DPPH dan inhibisi enzim tirosinase. Alternatif pelarut pengganti pelarut organik yang digunakan memiliki kepolaran yang berbeda-beda yaitu tween 20, tween 80, span 20, dan span 80. Hasil penelitian menunjukkan nilai IC50 rata-rata yang diperoleh dari daya peredaman radikal bebas DPPH ekstrak daun murbei menggunakan tween 20, tween 80, span 20 dan span 80 beturut-turut adalah 9874, 12797, 23131, dan 41844 bpj. Sedangkan aktivitas inhibisi enzim tirosinase ekstrak daun murbei hasil ekstraksi menggunakan alternatif pelarut tween 20, tween 80, span 20 dan span 80 dimana pada konsentrasi 45000 bpj masing-masing ekstrak memberikan % inhibisi sebesar 19,62, 17,26, 15,84, dan 14,18 %. Dengan demikian, dalam penlitian ini alternatif pelarut yang paling baik digunakan untuk penerapan green extraction pada daun murbei adalah tween 20.
ANALISIS FAKTOR YANG MEMPENGARUHI BIAYA TERAPI PENYAKIT HIPERTENSI PADA PASIEN RAWAT INAP RUMAH SAKIT X Aris Fadillah
Jurnal Farmasi Islam Kalimantan Vol 1, No 1 (2024): Eksplorasi Kefarmasian Komprehensif: Pendekatan In Silico, Teknologi Sediaan Ala
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jfik.v1i1.15398

Abstract

Prevalensi hipertensi di Indonesia masih tinggi dimana penyakit ini termasuk dalam 10 penyakit terbanyak di Indonesia. Penyakit ini mengakibatkan beban ekonomi yang signifikan pada Masyarakat sehingga perlu adanya analisis ekonomi pada biaya medisnya. Penelitian ini bertujuan untuk mengetahui factor apa saja yang dapat mempengaruhi biaya terapi pada pasien hipertensi. Analisis dilakukan dengan menggunakan metode statistic untuk mengetahui signifikasi hubungan antara variabel dengan biaya medis pasien hipertensi. Variabel yang diteliti pada penelitian ini meliputi keparahan hipertensi, adanya penyakit penyerta, adanya penyakit penyulit serta kelas perawatan. Pada penelitian ini didapatkan nilai signifikasi pada variabel keparahan hipertensi (0.598), penyakit penyerta (0.857), penyakit penyulit (0.890) dan kelas perawatan (0.471). Semua variabel tidak berbeda secara signifikan. Dapat disimpulkan bahwa keparahan hipertensi, adanya penyakit penyerta, adanya penyakit penyulit serta kelas perawatan tidak berpengaruh secara signifikan terhadap biaya medis pasien.
Hubungan Kualitas Pelayanan Kefarmasian Terhadap Kepuasan Pasien Rawat Jalan RS Bhayangkara TK. III Banjarmasin Maulina Lisdawati; Nily Su’aida; Aris Fadillah
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1286

Abstract

Background: The quality of pharmaceutical services is a crucial factor in the success of treatment and patient satisfaction. Objective: This study aims to analyze the relationship between the quality of pharmaceutical services and the satisfaction of outpatients at RS Bhayangkara TK. III Banjarmasin. Methods: This study employs a descriptive quantitative method with a survey approach, where data is collected through questionnaires distributed to patients receiving services at the hospital’s pharmacy department. Results: The results indicate a significant relationship between the quality of pharmaceutical services and patient satisfaction (p–value = 0,000 ≤ 0,05) analyzed through five dimensions of service quality: tangibility, reliability, responsiveness, assurance, and empathy. The Chi-Square test analysis showed that all these dimensions positively contribute to patient satisfaction. Additionally, this study evaluated the waiting time for both compounded and non-compounded medications, revealing that the hospital’s pharmacy services comply with the time standards set by the Ministry of Health. Conclusions: This study confirms the significant relationship between the quality of pharmaceutical services and outpatient satisfaction at Bhayangkara level III Hospital. Higher service quality, greater outpatient satisfaction, highlighting the need for continuous improvement in pharmaceutical services.
Evaluasi Potensi Interaksi Obat pada Pengobatan Pasien ISPA Anak Rawat Inap di Rumah Sakit Kota Banjarmasin. Aris Fadillah; Hasniah Hasniah; Juwita Ramadhani; Muliyani Muliyani; Muhammad Hasan Andriyanto; Nily Su’aida
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 2 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i2.1499

Abstract

Introduction: Drug interactions represent a clinically significant drug-related problem that may compromise therapeutic efficacy and increase the risk of adverse events. In pediatric patients with acute respiratory infections (ARIs), the use of multiple medications is common, potentially elevating the likelihood of drug interactions. Objective: This study aimed to evaluate the potential drug–drug interactions in hospitalized pediatric patients diagnosed with ARIs in Banjarmasin, Indonesia. Methods: A retrospective descriptive study was conducted using secondary data retrieved from the Hospital Management Information System. All medication regimens administered to pediatric inpatients with ARIs from January to June 2024 were analyzed. Drug interaction screening was performed using the Drugs.com Interaction Checker application. Results: Among 81 patients who met the inclusion criteria, 7 patients (8.64%) received treatment regimens with potential drug–drug interactions, accounting for a total of 8 interaction events (mean 1.14 interactions per affected patient). All identified interactions were classified as moderate in severity. Pharmacodynamic interactions were predominant (87.50%), whereas pharmacokinetic mechanisms comprised the remaining 12.50%. The most frequently observed potential interaction was between gentamicin and ceftriaxone (62.50%). Conclusion: Although the prevalence of potential drug interactions in this study was relatively low, their presence—particularly moderate-level pharmacodynamic interactions—warrants systematic clinical pharmacy monitoring to enhance patient safety and prevent undesirable clinical outcomes in pediatric ARI management.