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Rohama, Rohama
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Uji Aktivitas Antibakteri Ekstrak Daun Pulutan (Urena lobata L) Terhadap Bakteri Staphylococcus aureus: Antibacterial Activity Test of Pulutan Leaf Extract (Urea lobata L) Againt Staphylococcus aureus Fitriani, Dyah; Rohama, Rohama; Darsono, Putri Vidiasari; Hakim, Ali Rakhman
Jurnal Surya Medika (JSM) Vol. 10 No. 3 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i3.9006

Abstract

Penyakit infeksi merupakan suatu penyakit yang disebabkan karena virus, bakteri, protozoa ataupun jamur. Penggunaan antibiotik dalam pengobatan infeksi dapat menimbulkan efek samping dan resistensi. Daun pulutan secara empiris digunakan sebagai penurun panas, rematik, luka, bisul, dan sebagai antiseptik. Daun pulutan mengandung metabolit sekunder alkaloid, saponin, dan flavonoid yang diduga memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk menguji aktivitas antibakteri ekstrak daun pulutan (Urena lobata L) terhadap bakteri Staphylococcus aureus, menentukan Konsentrasi Hambat Minimum (KHM) dan Konsentrasi Bunuh Minimum (KBM) ekstrak daun pulutan (Urena lobata L) Terhadap bakteri Staphylococcus aureus. Metode yang digunakan pada penelitian ini adalah true experimental. Pengujian aktivitas antibakteri menggunakan metode difusi cakram dan dilusi cair. Kemudian data dianalisis menggunakan Kruskal-Wallis dan Mann Whitney. Hasil ekstrak daun pulutan memiliki aktivitas antibakteri pada konsentrasi 100% zona hambat 14,09 mm dan konsentrasi 80% zona hambat 11,09 mm. Nilai KHM terdapat pada konsentrasi 80% dan tidak memiliki nilai KBM. Hasil uji statistik menunjukan terdapat perbedaan bermakna p value 0,004 pada Kruskall Wallis dan pada Mann Whitney menunjukan p value 0,025. Dapat disimpulkan Daun Pulutan (Urena lobata L) memiliki aktivitas antibakteri kategori kuat. Nilai KHM terdapat pada konsentrasi 80% dan tidak memiliki nilai KBM terhadap bakteri Staphylococcus aureus.
P Profil Kromatografi Dan Penetapan Kadar Flavonoid Total Fraksi Etil Asetat Daun Kalangkala (Litsea Angulata Blum) Menggunakan Spektrofotometri Uv-Vis: Profil Kromatografi Dan Penetapan Kadar Flavonoid Total Fraksi Etil Asetat Daun Kalangkala (Litsea Angulata Blum) Menggunakan Spektrofotometri Uv-Vis Mardlatillah, Mardlatillah; Rohama, Rohama; Kurniawati, Darini
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.276

Abstract

Background: Kalangkala is a fruit plant typical of Kalimantan and belongs to the species of the genus Litsea which is thought to have potential as a natural antioxidant. Empirically, some people in South Kalimantan use the kalangkala plant, especially the seeds of the fruit, to treat boils. One of the compounds that have antioxidant and antibacterial content is flavonoids.Objectives: To determine the thin layer chromatography profile of the total flavonoid compound of the ethyl acetate fraction and to calculate the total flavonoid content of the ethyl acetate fraction of the leaf extract of Kalangkala (Litsea angulata Blum).Method: Thin Layer Chromatography Profile and Determination of Total Flavonoid Content of the Ethyl Acetate Fraction of Kalangkala Leaf Extract using the UV-Vis Spectrophotometry method. The data were then analyzed qualitatively and quantitatively.Results: The chromatographic profile of the total flavonoids of the ethyl acetate fraction of Kalangkala leaf eluent that was most optimal was Ethyl acetate : n-Hexane (3:7) because it showed the most stains, namely 5 stains. And in the uv-vis spectrophotometry method, the total flavonoid content of the ethyl acetate fraction of Kalangkala leaves (Litsea angulata Blum) was 0.9 mg QE/g.Conclusion: Kalangkala leaf extract on the TLC profile using ethyl acetate : n-Hexane (3:7) showed a total of 5 stains. And the value of the total flavonoid content of the ethyl acetate fraction of kalangkala leaves was 0.9 mg QE/g.
F Formulasi dan Antibakteri Sediaan Sabun Cair Ekstrak Daun Sembung (Blumea Balsamifera) terhadap bakteri Staphylococcus aureus: Formulasi dan Evaluasi Romadhina, Rodhiatul; Budi, Setia; Rohama, Rohama
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.400

Abstract

Background: The skin is a part that is susceptible to exposure to chemical, physical substances as well as bacteria, fungi and viruses. The bacteria that is often found on the skin is Staphylococcus aureus. To overcome this, soap making needs to be done, one of which uses sembung leaf extract which has biological activity as antibacterial. Objective: Extracting sembung leaves and making formulations of antibacterial liquid soap preparations of sembung leaf extracts and analyzing antibacterial preparations of liquid soap preparations of sembung leaf extracts Methods: The research method method used is experimental with true experimental design and the research design uses post test only with control group design. Making 3 kinds of antibacterial liquid soap formulations sembung leaf extract with concentrations of 5%, 7%, and 10%. Then evaluation includes pH, organoleptic, high foam, viscosity, and antibacterial test. Results: Based on the results of the organileptic test, there was no difference between each formulation of liquid soap extract from Sembung (Blumea balsamifera) leaf extract. Then in the pH test, it is included in the vulnerable pH of liquid soap, namely pH 8-11. After that, in the foam height test, the results of the foam height test were included in the foam height test vulnerable, namely 13-220 mm. Then, the viscosity test results obtained that the viscosity test is included in the viscosity test vulnerability, namely 400-4000 cPs. Finally, the anti-bacterial test obtained clear results of the diameter of the inhibition zone in each formulation. Conclusion: All formulations meet the SNI standard for liquid soap for pH testing, organoleptic testing, high foam testing, and viscosity testing. In antibacterial testing against Staphylococcus aureus bacteria using the disc method the best formula was obtained, namely a concentration of 5%.
U Uji Aktivitas Antibakteri Ekstrak Daun Pulutan (Urena lobata L) Terhadap Bakteri Streptococcus pyogenes Pusvita, Shela; Rohama, Rohama; Yuwindry, Iwan; Darsono, Putri Vidiasari
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.420

Abstract

Background: Pharyngitis or sore throat has a fairly high prevalence rate in Indonesia caused by Streptococcus pyogenes bacteria. Pulutan has experience as a medicine for sore throat, rheumatic fever, antipyretic, fracture, antifertility, and vaginal discharge. Based on research on ethanol extract that was done previously, pulutan leaf extract has antibacterial activity. Objective: To determine the antibacterial activity of pulutan leaf extract (Urena lobata L) which has the potential as an antibacterial against the growth of Streptococcus pyogenes and to determine the minimum inhibitory concentration and minimum killing concentration. Methods: This type of true experimental research design, namely research methods that look for causal relationships between independent and dependent variables. Antibacterial testing using disc diffusion and dilution methods. With concentrations of 100%, 75%, 50%, 25%, positive control amoxicillin and DMSO negative control. Results: The results of the disc diffusion test were able to inhibit the growth of the Streptococcus pyogenes bacteria which was indicated by the presence of a clear zone around the disc paper. The results of the dilution test obtained the MIC value at a concentration of 50% indicated by the media tube which looks clear. There was no KBM value at all the concentrations of the extracts tested, indicated by the growth of bacteria in the test medium. Conclusion: Pulutan leaf extract (Urena lobata L) has antibacterial activity which is indicated by the presence of an inhibition/clear zone around the disc paper. MIC results found at a concentration of 50%, KBM results on pulutan leaf extract (Urena lobata L) did not have killing power at all concentrations. Keywords: Antibacterial, Pulutan Leaf Extract (Urena lobata L), Streptococcus pyogenes.
A Aktivitas Antioksidan dan Penetapan Kadar Flavonoid Daun Sirih Merah (Piper crocatum Ruiz & Pav) Dengan Variasi Ukuran Partikel Serbuk Simplisia Oktavia, Rissa; Rohama, Rohama; Saputri, Rina
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 1 (2023): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i1.422

Abstract

Background: Red betel (Piper crocatum Ruiz & Pav) is a medicinal plant that is used empirically by the people of Tehang, Central Kalimantan for wound healing. The ability of red betel leaves to heal wounds is associated with the anti-inflammatory properties of the secondary metabolites of the flavonoid class contained therein which also have a role as a source of antioxidants. Particle size will affect the amount of bioactive compounds in an extract. Objective: To determine the difference in antioxidant activity and flavonoid content ethanol extract of red betel leaf in a variation of particle size simplisia powder. Methods: True experimental quantitative research which divided into two experimental groups, namely red betel leaf extract with a mesh particle size of 40/60 and 60/80. Testing of antioxidant activity with the DPPH method and determining the levels of flavonoids with the UV-Vis Spectrophotometry method. Results: The results of antioxidant activity based on IC50 values at 40/60 and 60/80 mesh particle sizes is 5.96 ppm and 2.74 ppm. The results of flavonoid content determination at 40/60 and 60/80 mesh particle size is 1.448 mg QAE/g and 3.5 mg QAE/g. Statistical analysis with the Mann Whitney test showed a significant difference (p value 0.025 <0.05). Conclusion: There is a significant difference with the variation of particle size on the antioxidant activity and levels of flavonoids. The highest antioxidant activity and flavonoid levels were observed in extracts with a mesh particle size of 60/80. The smaller the particle size, the stronger the antioxidants and the higher the levels of flavonoids.
E Etnomedicine Tumbuhan Obat di Masyarakat Desa Belangian, Kalimantan Selatan: Syahfitri, Laili Shinta Ayu; Nastiti, Kunti; Kurniawati, Darini; Rohama, Rohama
Jurnal Pelayanan Kefarmasian dan Sains Vol 4 No 2 (2024): Journal of Pharmaceutical Care and Sciences (JPCS)
Publisher : LPPM Universitas Sari Mulia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33859/jpcs.v4i2.549

Abstract

Background: The diversity of tribes and cultures in Indonesia makes culturaldifferences and traditional knowledge, one of which is in utilizing plants for thetreatment of a disease. One of the widespread tribes on the island of Kalimantanthat is thick with traditional medicine is the Banjar Tribe located in BelangianVillage, South Kalimantan. Ethnomedisin is a treatment by certain ethnicities basedon hereditary traditions in traditional medicine, in this case the use of medicinalplants.Objective: The purpose of this study was to determine the ethnomedicine ofmedicinal plants used by the Banjar Tribe of Belangian Village, Aranio District,South Kalimantan Province.Methods: This research is descriptive using qualitative and quantitative methods.Quantitative analysis with Fidelity Level (FL) calculations for each type ofmedicinal plant.Result: Based on the results of research from 38 informants, 58 species with 36families were obtained. There are 50 diseases that can be treated from 58 types ofmedicinal plants. The most popular method of processing is boiled 56.89 then drunk72.41%. The most widely used part of medicinal plants is the leaf part of 41.73%.Five types of plants with the highest FL values that stated effectiveness for treatmentwere Cymbopogon citratus 86.84%, Zingiber officinale 78.94%, Jatropha multifidaL 73.64%, Peronema canescens jack 68.42%, Syzygium polyanthum 65.78%. Thetradition of treatment with medicinal plants by the Banjar Tribe has been passeddown for generations with the value of local wisdom in its use.Conclusion: There are 58 types of medicinal plants that can be used as medicineor relief for certain diseases by the people of the Banjar Tribe, Belangian Village.With the highest FL value of five is found in Cymbopogon citratus plants 86.84%,Zingiber officinale 78.94%, Jatropha multifida L 73.64%, Peronema canescensjack 68.42%, Syzygium polyanthum 65.78%.
Determination of Flavonoid Levels and Anti-Inflammatory Activity of Lime Root Extract (Citrus aurantifolia) by Granuloma Pouch Method Mukti, Yusuf Anggoro; Rohama, Rohama; Jannah, Ghina Raudhatul; Rizantha, M. Iqbal; Daud, Muhammad Alfian
Berkala Kedokteran Vol 21, No 2 (2025)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v21i2.24410

Abstract

Non-communicable diseases (NCDs) are still the leading cause of death at the global level. In Indonesia, NCDs contribute 71% of the total mortality rate. One of the causes of non-communicable diseases is the occurrence of oxidative stress in the body which is a condition of imbalance between free radical compounds and antioxidants. One of the sources of free radical formation in the body is when the inflammatory process occurs. Lime is used by the Indonesian people as a seasoning for cooking or empirically as an appetite enhancer, antipyretic and antibacterial. Research states that  lime root extract has very strong antioxidant activity with an IC50 value of 24.81 ppm and positively contains alkaloids, flavonoids, saponins and tannins. Flavonoids are thought to act as antioxidants and anti-inflammatory through their ability to donate hydrogen atoms and the ability to bind prostaglandins, COX-1 and COX-2 and lipooxygenase enzymes. The very strong antioxidant activity and the presence of flavonoids contained make lime root have the potential as an anti-inflammatory. Determination of flavonoid levels of lime root extract using UV-Vis spectrophotometry method with quercetin as a comparison and testing of anti-inflammatory activity of lime root extract using the Granuloma Pouch  method using mouse test animals. The results showed that the total flavonoid level was 36.8 mg QE (Quersetin Equialen)/g or 3.68%. And itexerts an anti-inflammatory effect through its ability to reduce the volume of exudate, lower the total exudate leukocytes, and lower the number of neutrophils in the exudate, most notably at a concentration of lime root extract of 20%.
Pelatihan dan Pendampingan Kader Kesehatan melalui Media Flashcard untuk Meningkatkan Kesadaran Herbavigilans dan Rasionalitas Penggunaan Tanaman Obat [ Training and Assistance of Health Cadres through Flashcard Media to Increase Awareness of Herbavigilance and the Rationality of the Use of Medicinal Plants] Atmaja, Dewi Susanti; Rohama, Rohama; Latif, Abdul; Raihanah, Raihanah; Tazkiyah, Aulia; Nurhidayah, Dea; Aulia, Devina; Khatimah, Husnul; Yuniar, Nabila; Dagau, Lelie; Syifha, Nor; Amelia, Rina; Gunawan, Prayogo Aldi; Abidin, Zainul
Indonesia Berdaya Vol 7, No 1 (2026)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.20261363

Abstract

This community service activity was carried out in Danda Jaya Village, Rantau Badauh District, Barito Kuala Regency, with the aim of increasing awareness of herbavigilance and rationality of the use of medicinal plants among the community. This program uses a Participatory Action Research (PAR) approach that emphasizes the activity involvement of the community in every stage of the activity. The target of the activity consisted of Posyandu cadres with a total of 20 participants. The implementation of the activity lasted for three months and included three main stages, namely preparation, implementation, and evaluation. In the preparation stage, coordination was carried out with the village government and an initial survey regarding the types and patterns of use of medicinal plants. The implementation stage included counseling, training and mentoring, as well as the formation of the Danda Jaya Village Herbavigilance Monitoring Group as an effort to sustain the program. The results of the evaluation showed that there was a significant increase in the average value of cadre knowledge from 49,5 ± 13.17 to 82.0 ± 9.51, with an increase of 32.5% and a statistically significant difference (p less than 0.001). The distribution of categories shows a large shift from the “less” to the “good” and “excellent” levels. Before the training, the majority of cardes (85%) were in the “less” and “sufficient” categories, while after the training, 85% had reached the “good” to “very good” category. These results prove that herbavigilance-based training with the support of flashcard media is effective in increasing cardes understanding of the safety of using medicinal plants safely and rationally. Although the increase is not too large, this activity has succeede in fostering a new understanding of the importance of monitoring the side effects of medicinal plants and encouraging the public to be more careful in their use. This program has proven to be effective in educating the community while strengthening the role of villages as active actors in maintaining health based on local potential. Abstrak. Kegiatan pengabdian kepada masyarakat ini dilaksanakan di Desa Danda Jaya, Kecamatan Rantau Badauh, Kabupaten Barito Kuala, dengan tujuan meningkatkan kesadaran herbavigilans dan rasionalitas penggunaan tanaman obat di kalangan masyarakat. Program ini menggunakan pendekatan Participatory Action Research (PAR) yang menekankan keterlibatan aktif masyarakat dalam setiap tahapan kegiatan. Sasaran kegiatan terdiri dari kader posyandu dengan total peserta sebanyak 20 orang. Pelaksanaan kegiatan berlangsung selama tiga bulan dan mencakup tiga tahapan utama, yaitu persiapan, pelaksanaan, dan evaluasi. Pada tahap persiapan dilakukan koordinasi dengan pemerintah desa serta survei awal mengenai jenis dan pola penggunaan tanaman obat. Tahap pelaksanaan mencakup penyuluhan, pelatihan dan pendampingan, serta pembentukan Kelompok Pemantau Herbavigilans Desa Danda Jaya sebagai upaya keberlanjutan program. Hasil evaluasi menunjukkan adanya peningkatan nilai rata-rata pengetahuan kader meningkat signifikan dari 49,5 ± 13,17 menjadi 82,0 ± 9,51, dengan peningkatan sebesar 32,5% dan perbedaan yang bermakna secara statistik (p kurang dari 0,001). Distribusi kategori menunjukkan pergeseran besar dari tingkat “kurang” ke “baik” dan “sangat baik”. Sebelum pelatihan, mayoritas kader (85%) berada pada kategori “kurang” dan “cukup”, sedangkan setelah pelatihan, 85% sudah mencapai kategori “baik” hingga “sangat baik”. Hasil ini membuktikan bahwa pelatihan berbasis herbavigilans dengan dukungan media flashcard efektif dalam meningkatkan pemahaman kader tentang keamanan penggunaan tanaman obat secara aman dan rasional. Meskipun peningkatannya tidak terlalu besar, kegiatan ini berhasil menumbuhkan pemahaman baru tentang pentingnya pengawasan terhadap efek samping tanaman obat serta mendorong masyarakat untuk lebih berhati-hati dalam penggunaannya. Program ini terbukti efektif dalam mengedukasi masyarakat sekaligus memperkuat peran desa sebagai pelaku aktif dalam menjaga kesehatan berbasis potensi lokal.
Skrining Fitokimia dan Potensi Fraksi Etil Asetat Ekstrak Bajakah Tampala (Spatholobus Littoralis Hassk) sebagai Antikolestrol dengan Metode Liebermann-Burchard Chicade, Anabaena; Nastiti, Kunti; Alawiyah, Tuti; Rohama, Rohama
RIGGS: Journal of Artificial Intelligence and Digital Business Vol. 4 No. 4 (2026): November - January
Publisher : Prodi Bisnis Digital Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/riggs.v4i4.3940

Abstract

Bajakah tampala (Spatholobus littoralis Hassk) merupakan tanaman obat tradisional yang secara turun-temurun dimanfaatkan oleh masyarakat Kalimantan Tengah untuk mengobati berbagai penyakit, seperti kanker, diabetes, tumor, kolesterol, serta mempercepat penyembuhan berbagai jenis luka. Salah satu kandungan bioaktif utama pada tanaman ini adalah flavonoid, yang diketahui memiliki aktivitas farmakologis sebagai antioksidan dan berpotensi menurunkan kadar kolesterol. Meskipun demikian, kajian ilmiah yang mengkaji secara spesifik potensi antikolesterol bajakah tampala masih relatif terbatas, sehingga diperlukan penelitian lebih lanjut untuk mendukung pemanfaatannya secara ilmiah. Penelitian ini bertujuan untuk mengetahui hasil skrining fitokimia serta potensi fraksi etil asetat dari ekstrak bajakah tampala sebagai agen antikolesterol. Penelitian dilakukan menggunakan metode eksperimental dengan rancangan pre-test control only group. Skrining fitokimia dilakukan secara kualitatif menggunakan berbagai pereaksi warna untuk mengidentifikasi golongan senyawa metabolit sekunder. Sementara itu, pengujian aktivitas antikolesterol secara kuantitatif dilakukan menggunakan spektrofotometer dengan metode Liebermann-Burchard. Hasil skrining fitokimia menunjukkan bahwa fraksi etil asetat bajakah tampala mengandung senyawa alkaloid, saponin, tanin, dan flavonoid. Uji aktivitas antikolesterol secara in vitro menunjukkan bahwa fraksi etil asetat mampu menurunkan kadar kolesterol pada berbagai konsentrasi, yaitu sebesar 22,317% pada konsentrasi 50 ppm, 26,039% pada 75 ppm, 28,226% pada 100 ppm, dan mencapai penurunan optimum sebesar 31,942% pada konsentrasi 125 ppm. Berdasarkan hasil tersebut, dapat disimpulkan bahwa fraksi etil asetat bajakah tampala memiliki potensi sebagai agen antikolesterol alami dan layak untuk diteliti lebih lanjut melalui uji in vivo serta uji toksisitas guna memastikan keamanan dan efektivitas penggunaannya
Formulasi dan Evaluasi Natural Liquid Soap Ekstrak Kulit Kayu Taya (Nauclea orientalis) dengan Kombinasi Robusta Coffe sebagai Antibacterial Putri, Mela Julia; Budi, Setia; Rohama, Rohama; Noval, Noval
RIGGS: Journal of Artificial Intelligence and Digital Business Vol. 4 No. 4 (2026): November - January
Publisher : Prodi Bisnis Digital Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/riggs.v4i4.5651

Abstract

Latar Belakang :  Infeksi kulit akibat bakteri Staphylococcus aureus masih menjadi permasalahan kesehatan masyarakat, terutama di negara berkembang seperti Indonesia. Infeksi ini dapat menyebar dengan cepat dan menyebabkan gangguan seperti pioderma, terutama pada anak-anak. Upaya pencegahan melalui penggunaan produk topikal antibakteri berbahan alami menjadi alternatif yang aman dan efektif. Salah satu bahan alami yang berpotensi adalah kulit kayu Taya (Nauclea orientalis) dan biji kopi Robusta (Coffea canephora) yang diketahui memiliki aktivitas antibakteri. Tujuan: Penelitian ini bertujuan untuk membuat dan mengevaluasi sabun cair alami (natural liquid soap) dengan kombinasi ekstrak kulit kayu Taya dan Robusta Coffee sebagai antibakteri. Metode: Metode yang digunakan adalah Quasy eksperimental dengan desain post test only control design, dengan tiga formulasi, yaitu F1 (2 g), F2 (4 g), dan F3 (6 g) ekstrak kulit kayu Taya, yang masing-masing dikombinasikan dengan 2,5 g ekstrak Robusta Coffee. Ekstrak diperoleh melalui metode refluks (kulit kayu Taya) dan maserasi (Robusta Coffee). Evaluasi dilakukan terhadap karakteristik fisikokimia sabun cair serta uji antibakteri terhadap Staphylococcus aureus menggunakan metode difusi cakram. Hasil: Hasil menunjukkan bahwa seluruh formulasi memenuhi standar mutu fisikokimia menurut SNI. Formula F3 menunjukkan zona hambat terbesar terhadap pertumbuhan Staphylococcus aureus, yang mengindikasikan efektivitas antibakteri tertinggi di antara formulasi lainnya. Simpulan: kombinasi ekstrak kulit kayu Taya dan Robusta Coffee dalam sediaan sabun cair alami memiliki potensi sebagai agen antibakteri topikal yang aman, efektif, dan layak untuk dikembangkan sebagai produk perawatan kulit berbasis herbal.
Co-Authors Abdul Latif Ali Rakhman Hakim Amalia, Ghina Rezki Amalia, Putri Rizky Amrina Rosyada Ananda, Hesti Aulia Andriani, Ine Anggia Puteri Anggraini, Livani Aryani, Norsarida Aryzki, Saftia Aulia, Devina Caroline, Putricia Chicade, Anabaena D, Putri Vidiasari Dagau, Lelie Dari, Kristina Wulan Daud, Muhammad Alfian Dede Mahdiyah, Dede Deviani, Norma Dewi Susanti Atmaja Elieser, Michael Fauzah Fauzah, Fauzah Fawwaz, Muhammad Taufiq Febriani, Agnesia Febriani, Carolina Fitriani, Dyah Fuaddah, Munawarah Gunawan, Prayogo Aldi Gusnianti, Elva Hastika, Febby Yulika Husna, Hafizatul Husnul Khatimah Ida Ayu Putu Sri Widnyani Indah Purnamasari Intan Intan Ira Wati, Nyoman Rindi Irawan, Angga Ismiadi, Rahmad Jannah, Ghina Raudhatul Khairunnisa Khairunnisa Khairunnisa, Aisya F. Khuluqia, Munirah Kristiana, Isha Desty Kristina, Isha Desty Kurniawati, Darini Kusnia, Risha I. K. Kusuma D, Muhammad Chandra Hadi Mahmudah Mahmudah Mardlatillah, Mardlatillah Martha, Dhea Yolanda Mawarid, M.T.F. Meisa, Devina Melviani, Melviani Mia Audina, Mia Mukti, Yusuf Anggoro Nabila, Putri Nabila, Yasmin Nastiti, Kunti Ningsih, Gusria Surya Ningtias, Radita Dia Ayu Noor Latifah Nor Erpiana, Indah Noval Noval Nugraha, Dyan Fitri Nurhidayah, Dea Octavia, Mutia Oktavia, Anisya Oktavia, Helda Oktavia, Rissa Pawestri, Hasna Priadi, Ota Punlin, Bella Aprilia Puspita, Melinda Dian Pusvita, Shela Putra, Dedy Karmadi Putri Vidiasari Darsono, Putri Vidiasari Putri, Mela Julia Rahayu, Desi Dwi Rahmadani Rahmadani Rahmawati, Rahmawati Rahmawati, Sinta Raihanah Raihanah Rianti, Nur Addina Rina Amelia Rina Safitri Rina Saputri Rizantha, M. Iqbal Romadhina, Rodhiatul Sadlia, Fitri Safitri, Bella Setia Budi Shinta, Laili Shinta Ayu Siti Aisyiyah, Siti Syahfitri, Laili Shinta Ayu Syifha, Nor Tazkiyah, Aulia Tumanggor, Agustina Hotma Uli Tuti Alawiyah Uljanati, Khairi Witin, Rafelita Septania B. Yanti, Novita Yuniar, Nabila Yuwindry, Iwan Zainul Abidin