Article Per Year (5 Year)
p-Index From 2021 - 2026
4.328
P-Index
This Author published in this journals
All Journal Jurnal Biologi Tropis Acta Biochimica Indonesiana JURNAL KAJIAN VETERINER Journal of Health Community Service Cendana Medical Journal Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) JUKEJ: Jurnal Kesehatan Jompa Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan
Anita Lidesna Shinta Amat
Universitas Nusa Cendana
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

Published : 38 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 38 Documents
Search

 1   2   3   4 
Uji Aktivitas Antibakteri Ekstrak Etanol Beras Putih (Oryza sativa L.) terhadap Pertumbuhan Bakteri Propionibacterium acnes Nevida Wiehelmina Fanggidae; Anita Lidesna Shinta Amat; Sangguana Marthen Jacobus Koamesah; Syahrir Syahrir
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 5 No. 2 (2026): Agustus: Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jurrike.v5i2.8798

Abstract

Background: Acne vulgaris is one of the most common skin problems and is closely associated with the activity of Propionibacterium acnes. Long-term use of antibiotics may lead to bacterial resistance; therefore, alternative antibacterial agents derived from natural products are needed. White rice (Oryza sativa L.) is known to contain bioactive compounds such as flavonoids, alkaloids, terpenoids, tannins, and saponins, which potentially exhibit antibacterial activity. Objective: This study aimed to evaluate the antibacterial activity of ethanol extract of white rice against the growth of Propionibacterium acnes. Methods: This research was conducted as a laboratory experimental study using a post-test only control group design. The ethanol extract of white rice was prepared by maceration using 70% ethanol. Antibacterial activity was evaluated using the disc diffusion method with extract concentrations of 100%, 50%, 25%, 12.5%, and 6.25%. Clindamycin was used as a positive control, while sterile distilled water served as a negative control. The parameter observed was the diameter of the inhibition zone. Result: The results of phytochemical screening showed that the ethanol extract of white rice (Oryza sativa L.) contains flavonoids, alkaloids, and terpenoids. Antibacterial activity test showed that the ethanol extract of white rice at concentrations of 100%, 50%, and 25% was able to inhibit the growth of Propionibacterium acnes by forming an inhibition zone, while at concentrations of 12.5% and 6.25% no inhibition zone was formed. The highest inhibition zone diameter was found at a concentration of 100%. The ethanol extract of white rice at concentrations of 100% (7.65 mm), 50% (6.77 mm), and 25% (6.15 mm) was able to inhibit the growth of Propionibacterium acnes, and was classified as having moderate inhibition. In contrast, at concentrations of 12.5% and 6.25%, the ethanol extract of white rice did not show any inhibitory activity detected in vitro using the disc diffusion method. The results of statistical analysis showed a p value <0.001, which means there was a significant difference in the diameter of the inhibition zone between the treatment groups. Conclusion: In conclusion, the ethanol extract of white rice exhibits antibacterial activity against Propionibacterium acnes in a concentration-dependent manner; however, its inhibitory effect remains lower than that of clindamycin.
Hubungan Tingkat Pengetahuan dengan Kepatuhan Konsumsi Tablet Tambah Darah (TTD ) pada Remaja Putri di SMP Negeri 6 Kota Kupang Alifah Fatira Islamiyah; Kartini Lidia; Anita Lidesna Shinta Amat; Gotfrieda Patiencia Taeng-Ob Adang
Jurnal Ilmiah Kedokteran dan Kesehatan Vol. 5 No. 1 (2026): Januari: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/klinik.v5i1.5308

Abstract

Anemia is a condition when the hemoglobin (Hb) level in the blood is less than normal. The most common cause of anemia is iron deficiency. Adolescent girls are at risk of anemia due to their rapid growth and lack of iron intake. Anemia in adolescent girls has various adverse effects both in the short and long term. The Indonesian government prevents anemia in adolescent girls with a program to provide blood supplement tablets to fulfill iron intake. This program is implemented through schools by providing free blood supplement tablets, one tablet per week. Of 80.9% of adolescent girls who received blood supplement tablets at school, only 1.4% consumed ≥ 52 tablets per year. One of the factors that influence adherence behavior is knowledge. Objective: This study aims to determine the relationship between the level of knowledge and compliance with the consumption of blood supplement tablets in adolescent girls at SMPN 6 Kupang. Method:  This research was an analytical observational research with a cross-sectional approach. This study was conducted on adolescent girls from SMPN 6 Kupang using a knowledge questionnaire and the Morisky Medication Adherence Scale-8 (MMAS-8) questionnaire. The sampling technique used stratified random sampling with 106 respondents who fulfilled the criteria of inclusion and exclusion. This study was analyzed by univariate and bivariate using chi-square test. Result: The results of the study were on 106 respondents, 64 respondents (60.4%) had poor knowledge and 42 respondents (39.6%) had good knowledge. Based on adherence to taking blood supplement tablets, 66 respondents (62.3%) had low adherence, 24 respondents (22.6%) had moderate adherence and 16 respondents (15.1%) had high adherence. The results of the chi-square test obtained p = 0.000 (p < 0.05). Conclusion: There is a significant correlation between the level of knowledge and adherence to the consumption of blood supplement tablets among adolescent girls at SMPN 6 Kupang.
The effect of green tea consumption on cholesterol reduction: a study among social service employees in East Nusa Tenggara Patricia Flamli Uma Mukin; Anita Lidesna Shinta Amat; Elisabeth Levina Sari Setianingrum; Magdarita Riwu
Acta Biochimica Indonesiana Vol. 7 No. 1 (2024): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.153

Abstract

Background: Hypercholesterolemia is a major risk factor for cardiovascular diseases, with elevated cholesterol levels prevalent in Indonesia. While pharmaceutical treatments are effective, they can be costly and cause side effects, prompting interest in natural remedies. Green tea, rich in bioactive compounds such as catechins, has shown potential in reducing cholesterol levels through its lipid-lowering and antioxidant properties. Objective: This study aimed to evaluate the effect of green tea consumption on total cholesterol levels in employees of the Social Service Office, East Nusa Tenggara Province, Indonesia. Method: An experimental study was conducted involving 38 participants aged 25–55 years, divided into a treatment group (n = 19) and a control group (n = 19). The treatment group consumed 240 ml of green tea twice daily for one week, while the control group received no intervention. Total cholesterol levels were measured using capillary blood and cholesterol test strips pre- and post-intervention. Data analysis was performed using the paired t-test. Results: The treatment group exhibited a significant reduction in total cholesterol levels (mean pre-treatment: 210.95 mg/dL; post-treatment: 188.26 mg/dL; p = 0.003). The control group showed no significant change (pre-treatment: 208.11 mg/dL; post-treatment: 214.37 mg/dL; p = 0.42). Conclusion: Green tea consumption for one week significantly reduced total cholesterol levels, demonstrating its potential as a natural remedy for managing hypercholesterolemia.
Antibacterial potential of celery (Apium graveolens L.) extract gel against Staphylococcus aureus Martinus Ezra Sunarno; Anita Lidesna Shinta Amat; Arley Sadra Telussa; Prisca Deviani Pakan
Acta Biochimica Indonesiana Vol. 7 No. 2 (2024): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.154

Abstract

Background: Staphylococcus aureus can cause furuncles or boils, painful nodules on the skin. Conventional topical therapies often lead to side effects such as contact dermatitis and pruritus, compounded by the increasing problem of antibiotic resistance. Natural ingredients like celery (Apium graveolens L.) offer promising alternatives due to their antibacterial properties and gentler effects. Objective: This study aimed to formulate a celery extract gel with ideal physical characteristics and evaluate its antibacterial potency against Staphylococcus aureus. Methods: Celery extract gel was prepared using HPMC, celery extract, methylparaben, propylparaben, and propylene glycol. Formulations with various celery extract concentrations were tested alongside mupirocin ointment (positive control) and gel base (negative control) against Staphylococcus aureus using the well-diffusion method. The results were analyzed using the One-Way ANOVA statistical test. Results: Celery extract gel demonstrated strong antibacterial potency at 25% (F1), 50% (F2), and 75% (F3) concentrations and very strong potency at 100% (F4). The One-Way ANOVA analysis showed a significant difference in the mean inhibitory zone diameter between treatment groups (p < 0.05). Conclusion: Celery extract gel exhibits significant antibacterial activity against Staphylococcus aureus, suggesting its potential as a natural alternative for topical therapy in managing skin infections.
The Relationship of Knowledge Levels About COVID-19 With COVID-19 Prevention Behavior In Oebobo Village Community Kupang Vania Carla Devina; Herman Pieter Wungouw; Anita Lidesna Shinta Amat; Dominikus Minggu
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.16326

Abstract

Introduction: COVID-19 is a virus that can be transmitted from human to human (human to human transmission). This virus has spread widely in China and even to other countries. This virus can spread because of the travel history of people who have been infected with the corona virus. The increase in COVID-19 in Indonesia is also based on the lack of public knowledge about COVID-19. The existence of correct information can help people to increase their knowledge. Misinformation can make people's understanding also change. Therefore, the level of community knowledge greatly influences people's behavior. Behavior is an action that can also be interpreted as all activities carried out by someone which is the result of external stimuli that explain the knowledge they have. Community behavior in preventing COVID-19 can help reduce the increase in the incidence of COVID-19. Purpose: The purpose of this study was to determine the relationship between the level of knowledge about COVID-19 and COVID-19 prevention behavior in the community in Oebobo Village, Kupang. Methods: This type of research was an observational analytic using amethod cross sectional conducted on the people of Oebobo Village, Kupang City. . Data were obtained by filling out the Knowledge Questionnaire about COVID-19 and the COVID-19 Prevention Behavior Questionnaire by 100 respondents who met the inclusion criteria. Sampling was done by using purposive random sampling technique. The results were analyzed univariately and bivariately using thecorrelation test Spearman. Results: Data from 100 respondents showed, 64.0% had a good level of knowledge, 32.0% had a sufficient level of knowledge and 4.0% had a poor level of knowledge. For preventive behavior, 68.0% had good behavior, 32.0% had moderate behavior and none had bad behavior. The results of the bivariate analysis with the correlation test Spearman showed the results of p= 0.114 (p> 0.05) Conclusion: There is no significant relationship between the level of knowledge about COVID-19 and COVID-19 prevention behavior in the community in Oebobo Kupang Village
Hubungan Tingkat Stres Akademik Dengan Keteraturan Siklus Menstruasi Pada Mahasiswi Preklinik Fakultas Kedokteran Universitas Nusa Cendana Helenri Juntari Salmay; Anita Lidesna Shinta Amat; Idawati Trisno
Cendana Medical Journal Vol 13 No 1 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i1.16329

Abstract

Latar Belakang : Menstruasi merupakan suatu perubahan fisiologis pada tubuh wanita secara berkala yang dipengaruhi oleh hormon reproduksi. Siklus menstruasi seorang wanita dapat terjadi secara teratur dan tidak teratur, seperti polimenore, oligomenore, dan amenore. Salah satu faktor yang dapat mempengaruhi keteraturan siklus menstruasi adalah stres. Sumber stres yang paling banyak dialami oleh mahasiswa adalah stres dalam bidang akademik. Mahasiswa kedokteran memiliki stres yang lebih tinggi dibandingkan dengan kelas lain karena tuntutan akademik yang tinggi dan kurikulum yang berbeda. Tujuan : Penelitian ini bertujuan untuk mengetahui hubungan tingkat stres akademik dengan keteraturan siklus menstruasi pada mahasiswa praklinis Fakultas Kedokteran Universitas Nusa Cendana. Metode : Penelitian ini merupakan penelitian observasional analitik dengan desain cross sectional yang dilakukan pada mahasiswa praklinis Fakultas Kedokteran Universitas Nusa Cendana. Pengumpulan data dilakukan dengan pengisian Medical Student Stresor Questionnaire (MSSQ) dan kuesioner keteraturan siklus menstruasi oleh 100 responden angkatan 2018, 2019 dan 2020 yang memenuhi kriteria inklusi. Pengambilan sampel dilakukan dengan teknik stratified random sampling . Hasilnya dianalisis secara univariat dan bivariat dengan menggunakan uji korelasi koefisien kontingensi. Hasil : Dari 100 responden, 51 responden mengalami stres berat, 31 responden mengalami stres sedang, 13 responden mengalami stres sangat berat, dan 5 responden mengalami stres ringan. Untuk keteraturan siklus menstruasi, 70 responden memiliki siklus menstruasi normal, 30 responden memiliki siklus menstruasi tidak normal, 28 responden mengalami oligomenore dan 2 orang mengalami polimenore. Hasil uji analisis bivariat dengan uji korelasi koefisien kontingensi menunjukkan hasil p = 0,151 (p>0,05) Kesimpulan : Tidak terdapat hubungan yang signifikan antara tingkat stres akademik dengan keteraturan siklus menstruasi pada mahasiswa praklinis Fakultas Kedokteran Universitas Nusa Cendana. Kata Kunci : Tingkat stres akademik, keteraturan siklus menstruasi, mahasiswa kedokteran
PENGARUH EKSTRAK ETANOL DAUN SIRIH MERAH (Piper crocatum) TERHADAP GAMBARAN HISTOPATOLOGI OTOT JANTUNG TIKUS (Rattus norvegicus) DIINDUKSI ALOKSAN Riky Alberth Lerrick; Efrisca Meliyuita Br. Damanik; Anita Lidesna Shinta Amat; Rr. Listyawati Nurina
Cendana Medical Journal Vol 13 No 2 (2025): Cendana Medical Journal
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/cmj.v13i2.22056

Abstract

Introduction: Red betel leaves (Piper crocatum) contain flavonoids, alkaloids, saponins, and tannins, which have antidiabetic properties. Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia due to impaired insulin secretion or action, leading to increased production of Reactive Oxygen Species (ROS). The antioxidants in red betel leaf extract are expected to reduce ROS formation and protect cardiac muscle from DM-induced damage.. Methods: This laboratory experimental study used a true experimental post-test only control group design. Thirty rats were divided into five groups: positive control (KK+), negative control (KK−), and treatment groups (KP1, KP2, KP3), each consisting of six rats. Histopathological features of cardiac muscle, including interstitial fibrosis, ventricular myocyte hypertrophy, and intramyocyte lipid deposits, were assessed. Data were analyzed using the Kruskal-Wallis test and Post Hoc LSD. Results: There was a significant difference in ventricular myocyte hypertrophy between groups (p = 0.009), but no significant differences were observed in interstitial fibrosis (p = 1.000) and intramyocyte lipid deposits (p = 0.866). Discussion: Red betel leaf extract at 150 mg/kg body weight effectively reduced ventricular myocyte hypertrophy in diabetic rats Conclusion: Red betel leaf extract significantly reduced ventricular myocyte hypertrophy but had no effect on fibrosis or intramyocyte lipid deposits.
Antibacterial Activity of Ethanol Extract of Red Betel Leaves (Piper crocatum) Against Propionibacterium acnes Angelina Victoria Sihombing; Desi Indria Rini; Rahel Rara Woda; Anita Lidesna Shinta Amat
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11714

Abstract

Propionibacterium acnes is a type of bacteria that typically exists on skin areas with many sebaceous glands, like the scalp and face. The exploration of natural antibacterial agents made from herbal plants is one approach to decrease resistance issues. One such plant utilized is red betel, scientifically known as Piper crocatum. The objective of this study is to assess the antibacterial properties of the ethanol extract from red betel leaves against Propionibacterium acnes. This study adopted a true experimental framework with a post-test only control group model. The red betel leaf extract was produced through maceration using a 70% ethanol solution, followed by evaporation until a concentrated extract was achieved. In this study, the treated groups included various concentrations: 100%, 50%, 25%, 12.5%, 6.25%, 3.125%, and 1.56%, alongside a positive control using clindamycin and a negative control using sterile aquades. The antibacterial testing was performed using the disc diffusion method, referred to as the Kirby-Bauer technique against Propionibacterium acnes bacteria. The analysis conducted was the One Way Anova statistical test. Findings from this study reveal that the extract of red betel leaves contains alkaloids, tannins, saponins, flavonoids, and terpenoids. The testing outcomes indicate that the average diameter of the inhibition zone resultant from each sample is 11.16 mm for the 100% concentration, 9.63 mm for the 50% concentration, 8.85 mm for the 25% concentration, 8.21 mm for the 12.5% concentration, 7.78 mm for the 6.25% concentration, 6.93 mm for the 3.125% concentration, and 0 mm for the 1.56% concentration. From the results, it can be concluded that the ethanol extract from red betel leaves exhibits antibacterial activity against the growth of Propionibacterium acnes.
Co-Authors Abdullah, Fatih Aji Winarso, Aji Alifah Fatira Islamiyah Angelina Victoria Sihombing Anjani, Ratih Anu, Helena Vaustina Arley Sadra Telussa Artawan, I Made Asan, Maria Ignatia De Loyola Ina Peni Ballo, Natasya Detami Sheline Br Damanik, Efrisca Meliyuta Br. Damanik, Efrisca Meliyuita Corputty, Dian Yelisa Damanik, Efrisca M. Br. Deri Riskiyanti Tallo Manafe Desi Indria Rini Dewanti, Intan Putri Djahi, Sri Nur Nur Saidah Djunaidi, Savitry R. Maudy Dominikus Minggu E D, Maria Agnes Efrisca Damanik Efrisca Meliyuita Br. Damanik Elisabeth Levina Sari Setianingrum Folamauk, Conrad Liab Hendricson Gotfrieda Patiencia Taeng-Ob Adang Gue, Ronaldo Osario Lau Haning, Andre Januar Dwi Putra Helenri Juntari Salmay Herman Pieter Louis Wungouw Herman Pieter Wungouw Hutasoit, Regina Marvina Idawati Trisno Indriarini, Desi Kapitan, Irene Krisanti Kareri, Dyah Gita Rambu Kartini Lidia Kause, Marthen Keba, Diorita Sely Koamesah, S.M.J lai, gloria harpazo Lenggu, Claritha Kaci Louis Lidia, Kartini Liwu, Apolonia Nogo Ly, Elsye Jasicha Magdarita Riwu Maria Agnes Etty Dedy Maria Fransiska Priska Yulianti Martinus Ezra Sunarno Mau Meta, Maria Chrisanti Nevida Wiehelmina Fanggidae Ngara, Cydri Anggreny Rade Dendo Nurina, Rr. Listyawati PAKAN, PRISCA DEVIANI Pao, Ressa Patricia Patricia Flamli Uma Mukin Prisca Deviani Pakan Prisca Deviani Pakan Rahel Rara Woda Ratu, Kristian Regina Marvina Hutasoit Riky Alberth Lerrick Rini, Desi Indria Riwu, Magdarita Sangguana Marthen Jacobus Koamesah Sasputra, I Nyoman Setianingrum, Elisabeth Levina Sari Setiawan, I Made Buddy Sianturi, Elaine Courtesy So’o, Rosina Wiwin Suban, Irenne Sovia Lestari Syahrir Syahrir Tandang, Fransiskus Toby, Tarsisius Ryang Vania Carla Devina Wahyuningrum, Stefany Adi Wardani, Nimas Prita Rahajeningtyas Kusuma Woda, Rahel Rara Wungouw, Herman P L Wungouw, Herman Pieter Louis