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All Journal GRADIEN The Journal of Pure and Applied Chemistry Research Jurnal Riset Kimia Jurnal Kimia dan Kemasan agriTECH Jurnal Kelautan Tropis Science and Technology Indonesia Wikrama Parahita : Jurnal Pengabdian Masyarakat ALCHEMY Jurnal Penelitian Kimia Martabe : Jurnal Pengabdian Kepada Masyarakat BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Jurnal Biosilampari: Jurnal Biologi Molekul: Jurnal Ilmiah Kimia Jurnal Ilmu Kefarmasian Indonesia Jurnal Mangifera Edu Jurnal Pengabdian Al-Ikhlas Jurnal Abdi Insani Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Sains dan Matematika Jurnal Kimia dan Kemasan Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Indonesian Journal of Community Empowerment and Service Molekul: Jurnal Ilmiah Kimia Abdi Reksa Bencoolen Journal of Pharmacy Rafflesia Journal of Natural and Applied Sciences (RJNAS) Jurnal Biosilampari: Jurnal Biologi
Morina Adfa
Jurusan Kimia, FMIPA, Universitas Bengkulu, Indonesia
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Oil Palm Leaves as an In-situ Bio-silica Source in Sustainable Synthesis of V2O5-SiO2 Yudha S., Salprima; Adfa, Morina; Wibowo, Risky Hadi; Reagen, Muhamad Alvin
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1148-1155

Abstract

Using ammonium vanadate and natural silica from oil palm leaves in situ at 900oC is a sustainable synthesis method for producing V2O5-SiO2 mixed oxides in the form of a brownish powder. Therefore, this study aims to investigate a more environmentally friendly alternative to synthesizing V2O5-SiO2 using oil palm leaves, a by-product from oil palm farming. The XRD analysis of the reaction products showed specific V2O5 peaks and broadened peaks, indicating the presence of amorphous silica. The Fourier transform infrared (FTIR) analysis, which revealed the presence of Si-O-Si and Si-O-V functional groups, also supported the characteristic assessment. In addition, X-ray fluorescence (XRF) analysis showed that V2O5 (46.70 mass%) and SiO2 (52.60 mass%) were present, along with small amounts of other possible metal oxides, such as P2O5, K2O, CaO, Fe2O3, Al2O3, and PdO.
Aktivitas Antibakteri Secara In-Vitro Ekstrak Metanol Excoecaria cochinchinensis Lour dan Kombinasinya dengan Obat Komersial Nurhasana, Devi; Febriansyah, Rahmaga; Avidlyandi, Avidlyandi; S., Salprima Yudha; Banon, Charles; Oktiarni, Dwita; Adfa, Morina
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1383

Abstract

The purpose of this study was to look into the antibacterial activity of methanolic extract of Excoecaria cochinchinensis as well as the effect of its combination with antibiotics on the growth of Klebsiella pneumoniae, Enterobacter aerogenes, and Staphylococcus epidermidis. The antibacterial activity test was carried out using the well diffusion method, and the combined effect of the extract and antibiotics was observed using the paper strip diffusion method. At various concentrations (25, 50, 75, 100, 150, 200, and 250 mg/mL), the extract significantly inhibited the growth of K. pneumoniae, E. aerogenes, and S. epidermidis. The inhibitory zone's diameter increased proportionally with the extract concentration. The growth of K. pneumoniae and S. epidermidis was then classified as extremely sensitive (+++) to the addition of the extract at 200 and 250 mg/mL concentrations, meanwhile, E. aerogenes’s with 250 mg/mL of the extract. Secondary metabolites such as oleanolic acid, arjunolic acid, scopoletin, kaempferol, quercetin, diterpenoid compounds, tannins, and other phenolics have been reported from E. cochinchinensis leaves and are thought to be responsible for its antimicrobial activity. The effect of the extract’s combination with antibiotics was insignificant compared to their individual activity, thereby classifying them as indifferent.
Bioprospeksi Senyawa Antibakteri dari Bakteri yang Berasosiasi pada Bulu Babi asal Kabupaten Kaur, Bengkulu Wibowo, Risky Hadi; Sipriyadi, Sipriyadi; Adfa, Morina; Prastya, M. Eka; Cahlia, Uci; Fahmi, Riziq Ilham Nur; Rothman, Dita Delia
Jurnal Kelautan Tropis Vol 28, No 3 (2025): JURNAL KELAUTAN TROPIS
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkt.v28i3.29412

Abstract

The digestive system of sea urchins functions to process organic material from food into bioactive compounds. . However, the direct exploitation of bioactive compounds from sea urchins may trigger ecological imbalances. These bioactive compounds can also be produced through interactions between sea urchins and their diverse associated bacteria within the body. Therefore, alternative methods are needed to obtain bioactive compounds without disrupting the aquatic ecosystem. This study aims to explore bioactive compounds from the associated bacteria of sea urchins (Stomopneustes variolaris Lamarck and Tripneustes ventricosus Lamarck) originating from Kaur Regency, Bengkulu. A total of 30 bacterial isolates were successfully obtained using Zobell Marine Agar (ZMA) medium. Potential isolates were identified through morphological observation, Gram staining, and biochemical tests. Antibacterial activity assays showed that 12 isolates had potential as antibacterial producers based on tests against Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Two isolates, TVL 6 and TVL 11, were able to inhibit all test bacteria. Additionally, assays using pellets and supernatants showed that all 12 isolates exhibited antibacterial activity, with 5 isolates showing activity in the supernatant. Isolates TVL 6 and TVL 11 were proven effective in inhibiting all test bacteria in both pellet and supernatant forms, with the highest inhibition observed against Staphylococcus aureus. These results indicate that the associated bacteria in the digestive tract of sea urchins have potential as candidates for antibacterial compound producers.   Sistem pencernaan bulu babi berfungsi untuk mengolah bahan organik dari makanan menjadi senyawa bioaktif. Namun, eksploitasi senyawa bioaktif dari bulu babi secara langsung dapat memicu ketidakseimbangan ekosistem. Senyawa bioaktif ini juga dapat dihasilkan melalui interaksi antara bulu babi dengan bakteri asosiasi yang beragam di dalam tubuhnya. Oleh karena itu, diperlukan metode alternatif untuk memperoleh senyawa bioaktif tanpa merusak keseimbangan ekosistem perairan. Penelitian ini bertujuan untuk mengeksplorasi senyawa bioaktif dari bakteri asosiasi bulu babi (Stomopneustes variolaris Lamarck dan Tripneustes ventricosus Lamarck) asal Kabupaten Kaur, Bengkulu. Sebanyak 30 isolat bakteri berhasil diisolasi menggunakan media Zobell Marine Agar (ZMA). Identifikasi isolat potensial dilakukan melalui pengamatan morfologi, pewarnaan Gram, dan uji biokimia. Uji aktivitas antibakteri menunjukkan bahwa 12 isolat memiliki potensi sebagai penghasil antibakteri berdasarkan pengujian terhadap kultur uji Bacillus subtilis, Escherichia coli, dan Staphylococcus aureus. Dua isolat, TVL 6 dan TVL 11, mampu menghambat semua bakteri uji tersebut. Selain itu, pengujian menggunakan pelet dan supernatan menunjukkan bahwa 12 isolat mampu menghasilkan aktivitas antibakteri, dengan 5 isolat menunjukkan aktivitas pada supernatan. Isolat TVL 6 dan TVL 11 terbukti efektif menghambat semua bakteri uji baik pada pelet maupun supernatan, dengan penghambatan tertinggi terhadap Stapylococcus aureus. Hasil ini mengindikasikan bahwa bakteri asosiasi dalam saluran cerna bulu babi memiliki potensi sebagai kandidat penghasil antibakteri. 
PELATIHAN PEMBUATAN ECOENZYME "CAIRAN SERBA GUNA" SEBAGAI BAHAN ALTERNATIF BIO-HANDSANITIZER DAN BIOFERTILIZER PADA KELOMPOK TANI DESA SUKA SARI, KECAMATAN KABAWETAN, KABUPATEN KEPAHIANG Wibowo, Risky Hadi; Sipriyadi, Sipriyadi; Adfa, Morina; Hidayah, Thoriqul; Indah Medani, Della; Silvia, Elsi; Wahyuni, Reza
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 1 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i1.376-384

Abstract

Limbah organik berupa sayuran dan buah-buahan di Desa Sukasari, Kabupaten  Kepahiang, Kota Bengkulu yang melimpah dapat dijadikan sebagai produk Eco-enzyme sebagai bahan alternatif pembuatan Bio-handsanitizer dan Biofertilizer. Dari hasil kegiatan pengabdian kepada masyarakat mengenai aplikasi pemanfaatan ecoenzyme dari limbah organik sebagai bahan alternatif pembuatan Bio-handsanitizer dan Bio-fertilizer, para kelompok tani  telah mengetahui dan memahami cara pembuatan dan manfaat ecoenzyme. Hal ini menunjukkan kegiatan pengabdian sukses dan mencapai sasaran. Sosialisasi dan demonstrasi pelatihan yang dilakukan memberikan hasil persentase yang baik ketika pemberian umpan balik kepada peserta. Maka dari itu kegiatan pengabdian ini diharapkan untuk dapat memberi solusi terhadap kasus  pengolahan serta penanganan limbah organik melalui pembuatan produk ecoenzyme sebagai bentuk pengolahan limbah organik, seperti limbah sisa buah dan sayur dan diharapkan dapat memberi manfaat berupa wawasan untuk dimanfaatkan dalam realisasi produk ecoenzyme di Desa Suka Sari, Kecamatan Kabawetan, Kabupaten Kepahiang. Sehingga kedepannya kelompok tani dapat mengelola limbah organik secara tepat sehingga menghasilkan produk bermanfaat seperti biohandsanitizer dan biofertilizer dengan nilai jual yang tinggi dan diharapkan bisa mengurangi penggunaan pupuk kimia.
Analisis Hubungan Kuantitaf Struktur Dan Aktivitas Sebagai Antioksidan Turunan Senyawa Apigenin Dengan Menggunakan Metode Recife Model 1 (RM 1) Puspasari, Jesi; Banon, Charles; Wiradimafan, Khafit; Avidlyandi, Avidlyandi; Adfa, Morina
RAFFLESIA JOURNAL OF NATURAL AND APPLIED SCIENCES Vol. 5 No. 2 (2025): Oktober
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/rjna.v5i2.47368

Abstract

Penelitian ini menggunakan kajian teoritis HKSA senyawa turunan apigenin menggunakan deskriptor sterik, hidropobik dan elektronik. Nilai deskriptor diperoleh berdasarkan perhitungan kimia komputasi menggunakan program Hyperchem 8.0.8 dengan menggunakan metode semiempirik Recife Model 1 (RM1). Data hasil perhitungan diolah menggunakan program SPSS versi 22.0 dengan metode analisis korelasi dan regresi linear berganda, sehingga diperoleh persamaan HKSA: IC50 = 55,725 + (6,063)Log P + (-0,045) ∆f + (-1,603) μ + (0,902)A n = 16; R = 0,927; R2= 0,859; SE = 2,088; F = 16,746. Dari persamaan HKSA, didapatkan prediksi senyawa yang sangat berpotensi sebagai antioksidan, yaitu 4’,5,7- Trihidroksi-3- metoksi flavon dengan nilai IC50 sebesar 1,51 (μM). Dengan membandingkan nilai IC50, didapatkan hasil bahwa gugus metoksi (OCH3) lebih meningkatkan aktivitas antioksidan dibandingkan dengan gugus etoksi (OC2H5).
Pengaruh Rasio Etanol-Air terhadap Rendemen dan Aktivitas Sitotoksik Ekstrak Daun Azadirachta Indica Sinaga, Samuel Billie Tua; Ramanda, Putri; Mawakhid, Oki Rokhim; Shari, Winda; Wiradimafan, Khafit; ., Avidlyandi; Adfa, Morina
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 5 No 1 (2026): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v5i1.2491

Abstract

Neem leaves (Azadirachta indica) are widely recognized as a rich source of diverse bioactive compounds that exhibit promising pharmacological activities, including anticancer potential. Nevertheless, studies investigating how variations in solvent composition influence extract yield and cytotoxic activity remain limited. Therefore, this research aimed to evaluate the effect of different ethanol–water solvent ratios (50%, 70%, and absolute ethanol) on both the extraction yield of neem leaves and their cytotoxic activity against Artemia salina Leach. The extraction procedure combined sonication and subsequent maceration using the three solvent systems to enhance compound recovery. Cytotoxic assessment was performed through the Brine Shrimp Lethality Test (BSLT) at concentrations of 1000, 500, 100, and 10 ppm, utilizing 48-hour-old larvae with three experimental replicates. Larval mortality was observed after 24 hours of exposure, and LC₅₀ values were determined using probit analysis and linear regression methods. The results demonstrated that extraction with 50% ethanol produced the highest yield (23.5%), followed by 70% ethanol (20.8%) and absolute ethanol (16.10%). In contrast, the strongest cytotoxic activity was observed in the 70% ethanol extract, which exhibited the lowest LC₅₀ value (62.87 ppm), followed by the 50% ethanol extract (64.23 ppm) and the absolute ethanol extract (99.15 ppm). These findings indicate that solvent ratio significantly influences both extraction efficiency and cytotoxic potency; however, extract yield was not directly correlated with cytotoxic activity. Importantly, all extracts demonstrated LC₅₀ values below 100 ppm, suggesting notable toxicity and highlighting their potential as candidates for developing anticancer raw materials.
Mixed Natural Rubber Latex and Co2SiO4/SiO2 Derived from Silica of Oil Palm Leaves and Cobalt Nitrate Yudha S, Sal Prima; Adfa, Morina; Istiqphara, Swadexi; Reagen, Muhamad Alvin; Sutanto, Teja Dwi
Molekul Vol 21 No 1 (2026)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2026.21.1.16369

Abstract

ABSTRACT. Cobalt nitrate solution is combined with oil palm leaf powder to produce a semisolid mixture. The resulting mixture is heated in a furnace at 500 °C for 5 h, producing a grey powder. X-ray diffraction (XRD) analysis of the product showed distinct peaks at 2θ values of 31.2°, 36.8°, 44.8°, 59.2°, and 65.1°, which were consistent with the presence of Co₃O₄/SiO₂. When a similar mixture was heated at 1000 °C for 5 h, a purple powder containing Co₂SiO₄/SiO₂ was obtained. XRD patterns of this material contained peaks at 2θ values of 25.4°, 32.2°, 34.1°, 35.6°, 36.5°, 52.2°, and 62.3°, which corresponded with Co₂SiO₄. The latter product was selected for further analysis, including Fourier-transform infrared (FTIR) spectroscopy which identified characteristic absorption bands at 588 cm⁻¹ and 672 cm⁻¹, alongside additional peaks at 817 cm⁻¹ and 1117 cm⁻¹, reflecting the formation of cobalt silicate. Energy-dispersive X-ray (EDX) analysis confirmed the presence of cobalt (20.7%), silicon (14.0%), and oxygen (45.5%), alongside minor quantities of other elements, while scanning electron microscopy (SEM) showed irregularly shaped, non-spherical particles with some aggregation and a cloudy network. Following characterization, the synthesized cobalt silicate was applied as a colorant in natural rubber latex. Preliminary observations suggest that it functioned effectively as a colorant and remains stable during extended storage. Keywords: Cobalt silicate, cobalt oxide, oil palm leaf (OPL), rubber latex, silica.
Co-Authors ., Avidlyandi A.A. Ketut Agung Cahyawan W Afif, Muhammad adli Agus Martono Agus Martono H. Putranto Alvin Reagen, Muhammad Andini, Vicka Arif Juliari Kusnanda Aswanda Aswin Falahudin Aswin Falahudin Aswin Falahudin Aswin Falahudin Avidlyandi, Avidlyandi Azizah Khusnul Charles Banon Della Faronica Della Indah Medani Deni Agus Triawan Devi Nurhasana Diana Andari Dina Erliana Dwita Oktiarni Eka Angasa Eka Angasa Elsi Silvia Endarwati Wiwik Endarwati Evi Maryanti Evi Maryanti Fahmi, Riziq Ilham Nur Falahudin, Aswin Febriansyah, Rahmaga Fitriani, Dyah Ghufira Ghufira Harlianto, Budi Helfi Eka Saputra Hendri Bustamam Herlina Herlina Herlina Herlina Herlita Widiyanti Hidayah, Thoriqul Indah Medani, Della Insin, Numpon Irfan Gustian Irfan Gustian Irfan Gustian Irfan Gustian Irfan Gustian Irmanida Batubara Juliari Kusnanda, Arif Khafit Wiradimafan Khafit Wirdimafan Khairani, Nurliza Khusnul Azizah Kurnia Farah Andina Liana Wahyuni Lisna Hamni M. Rafi Martono H.P, Agus Mawakhid, Oki Rokhim Meyola, Fenti Mohamad Rafi Mudyanto, Andre Muhamad Alvin Reagen Muhammad Alvin Reagen Munifilia Ekasari Munifilia Ekasari Nesbah Nesbah, Nesbah Novrianto Tarigan Nurhasana, Devi Nurwidiyani, Ria Pasaribu, Cahaya Perdani, Meka Saima Prastya, M. Eka Puspasari, Jesi Rahmaga Febriansyah Ramanda, Putri Reagen, Muhamad Alvin Reza Pertiwi Reza Wahyuni Ria Nurwidiyani Risky Hadi Wibowo Risky Hadi Wibowo Rochmah Supriati Rothman, Dita Delia Sal Prima Yudha S Sal Prima Yudha S SALPRIMA YUDHA S Salprima Yudha S. Shari Winda Shari, Winda Silvia, Elsi Sinaga, Samuel Billie Tua Sipriyadi Sri Wahyu Kurnia Putri Suci Sukma Taruna Asral Supriati, Rochmah Suryadi Jaya Swadexi Istiqphara Swadexi Istiqphara Swadexi Istiqphara, Swadexi Teja Dwi Sutanto Thoriqul Hidayah Triawan Deni Agus Triawan, Deni Agus Uci Cahlia Wafa Syahidah Wahyuni, Reza Welly Darwis Wibowo Risky Hadi Wibowo, Risky Hadi Winda Shari Wulan Aprilia Syafitri Yudha S Yudha S