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All Journal International Journal of Public Health Science (IJPHS) Farmasains : Jurnal Farmasi dan Ilmu Kesehatan BALI MEDICAL JOURNAL (BMJ) Media Penelitian dan Pengembangan Kesehatan Jurnal Tumbuhan Obat Indonesia Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Majalah Obat Tradisional JURNAL PENGABDIAN KEPADA MASYARAKAT UNEJ e-Proceeding Journal of Islamic Pharmacy The Indonesian Biomedical Journal Jurnal Farmasi Sains dan Komunitas Journal Of Vocational Health Studies FITOFARMAKA: Jurnal Ilmiah Farmasi PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Madaniya Farmasis: Jurnal Sains Farmasi Pharmaceutical Sciences and Research (PSR) Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan
Mangestuti Agil
Faculty Of Pharmacy, Universitas Airlangga
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Public Health Social Sciences

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Metabolite Profiling of the Environmental-Controlled Growth of Marsilea crenata Presl. and Its In Vitro and In Silico Antineuroinflammatory Properties Burhan Ma'arif; Faisal Akhmal Muslikh; Dilla Amalia; Anisah Mahardiani; Luthfi Achmad Muchlasi; Pramudita Riwanti; Maximus Markus Taek; Hening Laswati; Mangestuti Agil
Borneo Journal of Pharmacy Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i3.3262

Abstract

This study was aimed to evaluate the metabolite contents and antineuroinflammatory potential of Marsilea crenata Presl. grown under a controlled environmental condition. The antineuroinflammatory test has been carried out in vitro using ethanolic extract of M. crenata leaves on HMC3 microglia cells. An in silico approach was applied to predict the active compounds of the extract. The HMC3 microglia cells were induced with IFNγ to create prolonged inflammatory conditions and then treated with 96% ethanolic extract of the M. crenata leaves of 62.5, 125, and 250 μg/mL. The expression of MHC II was analyzed using the ICC method with the CLSM instrument. Metabolites of the extract were profiled using UPLC-QToF-MS/MS instrument and MassLynx 4.1 software. In silico evaluation was conducted with molecular docking on 3OLS protein using PyRx 0.8 software, and physicochemical properties of the compounds were analyzed using SwissADME webtool. The ethanolic extract of M. crenata leaves could reduce the MHC II expression in HMC3 microglia cells in all concentrations with the values 97.458, 139.574, and 82.128 AU. The result of metabolite profiling found 79 compounds in the extract. In silico evaluation showed that 19 compounds gave agonist interaction toward 3OLS, and three met all parameters of physicochemical analysis. The ethanolic extract of the environmental-controlled growth of M. crenata leaves antineuroinflammatory activity on HMC3 microglia cells. The extract was predicted to contain some phytoestrogen compounds which act as 3OLS agonists.
In Silico Molecular Docking and ADMET Analysis for Drug Development of Phytoestrogens Compound with Its Evaluation of Neurodegenerative Diseases Faisal Akhmal Muslikh; Reyhan Rahma Samudra; Burhan Ma’arif; Zulvikar Syambani Ulhaq; Suko Hardjono; Mangestuti Agil
Borneo Journal of Pharmacy Vol. 5 No. 4 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i4.3801

Abstract

Neurodegenerative disease is one of the problems faced by postmenopausal women due to estrogen deficiency. Phytoestrogen compounds can be used as an alternative treatment for diseases caused by estrogen deficiency by binding to their receptors through the estrogen receptor (ER) dependent pathway. With in silico studies, this study aims to predict how phytoestrogen compounds will stop neurons from dying by using the dependent ER pathway. Genistein, daidzein, glycitein, formononetin, biochanin A, equol, pinoresinol, 4-methoxypinoresinol, eudesmin, α-amyrin, and β-amyrin compounds were prepared with ChemDraw Ultra 12.0. Then their pharmacokinetic and pharmacodynamic properties were examined using SwissADME. Geometry optimization of the compound was performed using Avogadro 1.0.1, and molecular docking of the compound to the ERα (1A52) and ERβ (5TOA) receptors was performed using AutoDock vina (PyRx 0.8). The interaction visualization stage was carried out with Biovia Discover Studio 2021, while the toxicity values of the compounds were analyzed using pkCSM and ProTox II. The results showed that the equol compound met the pharmacokinetic, pharmacodynamic, toxicity criteria, and had similarities with the native ligand 17β-estradiol. Equol compound inhibits neurodegeneration via an ER-dependent pathway by binding to ERα (1A52) and ERβ (5TOA) receptors.
Uji Sitotoksistas Ekstrak Etanol 96% Daun Semanggi (Marsilea crenata Presl.) pada Sel hFOB 1.19 dengan Metode Microtetrazolium (MTT) Assay Burhan Ma'arif; Nabila Rosa; Meilina Ratna Dianti; Alif Firman Firdausy; Hening Laswati; Mangestuti Agil
FARMASIS: Jurnal Sains Farmasi Vol 1 No 1 (2020): Farmasis : Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Semanggi (Marsilea crenata Presl.) merupakan salah satu tanaman yang telah dimanfaatkan oleh masyarakat Indonesia, khususnya Jawa Timur, sebagai bahan makanan selama beberapa dekade. Marsilea crenata Presl. mengandung senyawa fitoestrogen memiliki struktur dan fungsi mirip estrogen dalam tubuh. Tujuan penelitian melakukan uji sitotoksisitas dan menentukan nilai IC50 dari ekstrak etanol 96 persen daun Marsilea crenata Presl. terhadap sel hFOB 1.19. Metode yang digunakan adalah microtetrazolium (MTT) assay dengan microplate reader. Sel dikultur pada microplate-96 well dan diberikan ekstrak dengan variasi dosis 62,5 ppm; 125 ppm; 250 ppm; 500 ppm; 1000 ppm; 2000 ppm dan 4000 ppm, kemudian ditambahkan reagen MTT 100μL, diinkubasi selama 2-4 jam dan ditambahkan SDS 10 persen sebagai stopper. Pembacaan hasil menggunakan microplate reader. Hasil dari pembacaan tersebut digunakan sebagai perhitungan nilai IC50 yang dapat menunjukkan tingkat sitotoksisitas ektrak etanol 96 persen Marsilea crenata Presl. Nilai IC50 yang didapatkan sebesar 2074,965 μg/ml. Berdasarkan hasil tersebut ekstrak etanol 96 persen Marsilea crenata Presl. dapat dikatakan aman dan tidak bersifat sitotoksik jika dikembangkan menjadi bahan obat.
Efek Neuroprotektif Fraksi Air Daun Semanggi (Marsilea crenata Presl.) secara In Vitro Burhan Ma'arif; Muslim, Menara; Riyanti, Anisa Eka; Guhir, Abdul Malik; Amalia, Dilla; Saidah, Nisfatul Lailatus; Anggraini, Wirda; Atmaja, Ria Ramadhani Dwi; Laswati, Hening; Agil, Mangestuti
FARMASIS: Jurnal Sains Farmasi Vol 2 No 1 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i1.3537

Abstract

Background: Estrogen deficiency can trigger several diseases, one of which is neurodegenerative. Neurodegenerative begins with neuroinflammation, which triggers the activation of microglia cells resulting in a pro-inflammatory activity. Potential and relatively safe therapy to use to overcome it is by using phytoestrogen compounds. Marsilea crenata Presl. is a plant that contains phytoestrogens. Objective: The purpose of this study was to analyze the neuroprotective effect of the water fraction of Marsilea crenata Presl. leaves which was shown by inhibition of neuroinflammation and marked by increased levels of MHC II against HMC3 microglia cells. Methods: IFN-γ is induced into HMC3 microglia cells for 24 hours to cause inflammatory conditions. Marsilea crenata Presl. leaves water fraction was given at a dose of 62,5; 125; and 250 µg / ml. Analysis of the neuroprotective effect of HMC3 microglia cells using the ICC method with the aid of the CLSM instrument. Results: The results of this study indicate that the water fraction of Marsilea crenata Presl. leaves can reduce MHC II expression at concentrations of 125 and 250 μg / ml with values ​​of 465,748 and 460,884 AU at p less than 0,005. Conclusion: This study concludes that the water fraction of Marsilea crenata Presl. has neuroprotective activity shown at doses of 125 and 250 μg/ml which can reduce MHC II expression in HMC3 microglia cells induced by IFN-γ. The ED50 value which has a neuroprotective effect is at a dose of 0,582 μg/ml.  
Efek Ekstrak Daun Marsilea crenata Presl. pada Aktivitas Lokomotor Ikan Zebra Burhan Ma'arif; Maimunah, Siti; Muslikh, Faisal A.; Saidah, Nisfatul L.; Fihuda, Destiya A. P.; Khotimah, Husnul; Agil, Mangestuti
FARMASIS: Jurnal Sains Farmasi Vol 3 No 1 (2022): FARMASIS: Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v3i1.5389

Abstract

Pendahuluan: Prevalensi penyakit neurodegeneratif meningkat tiap tahunnya dan mayoritas dialami perempuan yang mencapai fase menopause. Hal tersebut kemudian mengurangi kualitas hidup perempuan menopause. Penyakit neurodegeneratif pada wanita menopause sering diakibatkan oleh defisiensi estrogen, sehingga perlu adanya pengganti hormon estrogen dalam menjaga homeostasis sistem saraf pusat, salah satunya fitoestrogen. Salah satu tanaman yang mengandung fitoestrogen adalah semanggi (Marsilea crenata Presl.) Tujuan: Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak etanol daun M. crenata terhadap peningkatan aktivitas lokomotor ikan zebra. Metode: Penelitian ini dilakukan dengan induksi rotenon sebagai pengganggu aktivitas lokomotor ikan zebra, melalui pengukuran motilitas. Perlakuan dilakukan dengan dengan memberikan ekstrak etanol daun M. crenata pada dosis 2,5; 5; 10; dan 20 mg/mL untuk mengetahui pengaruh ekstrak terhadap peningkatan aktivitas lokomotor ikan zebra yang telah diinduksi rotenon. Pengamatan dilakukan dengan melihat kuantitas berenang ikan zebra setiap 5 menit pada hari ke 0; 7; 14; 21; dan 28. Kesimpulan: Pemberian ekstrak etanol 96 persen daun M. crenata dapat meningkatkan aktivitas lokomotor yang diketahui melalui peningkatan motilitas ikan zebra secara signifikan pada dosis optimum 2,5 mg/mL pada hampir tiap kelompok hari. Hal ini membuktikan ekstrak daun M. crenata berpotensi dalam mencegah progresifitas penyakit neurodegeneratif.
THE EFFECT OF SLIMMING HERBS TEA WITH DIETARY ADJUSTMENT TO THE RESULT OF ANTROPOMETRIC MEASUREMENT AMONG WOMEN MEMBER OF AEROBIC STUDIO Perslami, Resti; Puruhito, Edith Frederika; Agil, Mangestuti
Journal of Vocational Health Studies Vol. 1 No. 1 (2017): July 2017 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (162.161 KB) | DOI: 10.20473/jvhs.V1.I1.2017.1-6

Abstract

Background: Overweight is the accumulation of excessive fat that can harm health. People who are overweight usually have a size of body anthropometry more than normal, such as the size of the waist circumference (WC), upper arm circumference (UAC), and subcutaneous fat thickness (SFT). Women are more to being overweight, because metabolism in women is lower and body fat is more than men. They attempt to return to normal body weight, by following the fitness clubs, diet and so forth. In this study, researchers used a slimming herbs tea to help restore their body size. Purpose: This study was to determine the effects of slimming herbs tea with dietary adjustments to the results of anthropometric measurements in the group of gymnastic class women. Method: The method used is quasy experimental design with the design of "pre-posttest control group design”. The study was held for 14 days by the number of respondents 14 people. Respondents were divided into 2 groups: control and treatment (consumption of slimming herbs tea). Slimming herbs tea composition consisting of green tea, guazuma extracts, parameria extract, fennel extract and curcuma extract consumed 2 times a day after meals every day. Data were analyzed using SPSS with Paired T-Test. Result: The results showed slimming herbs tea with dietary adjustments can reduce the results of anthropometric measurements such as WC as much as 6,21 cm ,UAC as much as 2,2 cm ,and SFT as much as 2,7 mm. While the reducing measurement in control group, in WC as much as 2,57 cm, UAC as much as 1,6 cm, SFT as much as 1,4 mm. Conclusion: The effect of slimming herbs tea with dietary adjustment can reducing the result of anthropometric measurement more in the woman class of gymnastic
Metabolite Profiling of 96% Ethanol Extract from Marsilea crenata Presl. Leaves Using UPLC-QToF-MS/MS and Anti-Neuroinflammatory Predicition Activity with Molecular Docking Burhan Ma’arif; Denis; Arief Suryadinata; Artabah; Hening Laswati; Mangestuti Agil
Journal of Tropical Pharmacy and Chemistry Vol. 4 No. 6 (2019): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v4i6.213

Abstract

Phytoestrogen is a group of compounds that can replace the estrogen function in the body. One of its roles was as anti-neuroinflammatory by inhibiting the microglia M1 polarity activation. Marsilea crenata Presl. is a plant that suspected to contain phytoestrogens. The aim of this research was to determine the metabolite profile of 96% ethanol extract of M. crenata using UPLC-QToF-MS/MS, and prediction the anti-neuroinflammatory activity of compounds with molecular docking. The 100 ppm of 96% ethanol extract in DCM and methanol were injected 5 µl each into the UPLC-QToF-MS/MS, and then analyzed by Masslynx 4.1 software to determine the compounds. The result of metabolite profiling shows a total 59 compounds in both DCM and methanol. Molecular docking was done with Autodock 4.2.6. After being analyzed, there are 3 compounds that are predicted to have activities similar to 17?-estradiol, they are prochlorperazine, 12-Aminododecanoic acid, and 1-methyl-2-[(4-methylpiperazin-1-yl)methyl]benzimidaol-5-amine hydrochloride. The results showed that the three compounds were predicted to be phytoestrogen compounds from M. crenata leaves, which have potential as anti-neuroinflammatory.
Efek Penghambatan Ekspresi ER? Bebas oleh Fraksi n-Butanol Daun Semanggi (Marsilea crenata Presl.) pada Sel hFOB 1.19: Inhibitory Effect of Free-ER? Expression by n-Butanol Fraction of Semanggi (Marsilea crenata Presl.) Leaves on hFOB 1.19 Cells Burhan Ma’arif; Agnis Pondineka Ria Aditama; Faisal Akhmal Muslikh; Dewi Perwito Sari; Ira Purbosari; Hening Laswati; Mangestuti Agil
Jurnal Sains dan Kesehatan Vol. 3 No. 4 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i4.635

Abstract

Wanita pascamenopause dapat menyebabkan berbagai macam masalah kesehatan, diantaranya adalah osteoporosis yang diakibatkan karena gangguan produksi hormon estrogen dalam tubuh. Salah satu alternatif yang muncul dan berpotensi untuk menggantikan hormon estrogen adalah fitoestrogen. Daun M. crenata diketahui mengandung senyawa fitoestrogen. Tujuan dari penelitian ini adalah untuk mengetahui fraksi n-Butanol daun M. crenata dalam meningkatkan aktivitas osteoblas pada proses pembentukan tulang terhadap sel hFOB 1.19. Penelitian ini menggunakan metode ICC dengan bantuan instrumen CLSM. Penelitian ini dilakukan dengan pemberian fraksi n-Butanol dengan varian konsentrasi62,5; 125; dan 250 ppm, serta pemberian genistein sebagai kontrol positif pada sel hFOB 1.19. Hasil dari penelitian ini menunjukkan bahwa fraksi n-Butanol daun M. crenata memiliki kandungan senyawa estrogenik sebagai agen untuk meningkatkan aktivitas osteoblas melalui penurunan ekspresi ER? bebas sel hFOB 1.19 dan konsentrasi 62,5 ppm sebagai konsentrasi optimal dengan nilai ekspresi 594.108 AU.
Prediksi Aktivitas Fitoestrogenik Senyawa Golongan Flavonoid terhadap Receptor Estrogen ? (ER- ?) dengan pendekatan In Silico: Prediction of Phytoestrogenic Activity of Flavonoid Compounds against Estrogen Receptor ? (ER- ?) with In silico approach Denis Mery Mirza; Burhan Ma’arif; Ira Purbosari; Suko Hardjono; Mangestuti Agil
Jurnal Sains dan Kesehatan Vol. 3 No. 4 (2021): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v3i4.640

Abstract

Tubuh manusia akan mengalami penuaan dan menyebabkan kenaikan resiko penyakit dan pada akhirnya menyebabkan kematian. Fenomena tersebut dapat muncul salah satunya akibat penurunan homeostasis tubuh karena menurunnya hormon estrogen. Salah satu senyawa yang berpotensi mengatasi keadaan tersebut adalah fitoestrogen dari golongan flavonoid. Potensi senyawa flavonoid dengan aktivitas fitoestrogenik, dapat diketahui dengan melakukan pengamatan In silico terhadap Estrogen Receptor ? (ER-?) dengan molecular docking. Tujuan penelitian ini adalah untuk mengetahui mekanisme senyawa fitoestrogen melalui jalur ER-dependent lain seperti ER-?. Tahapan molecular docking dilakukan menggunakan plug-in Autodock Vina dalam PyRX 0.8. Hasilnya diketahui senyawa apigenin, quercetin, kaempferol, katekin, genistein dan daidzein memiliki interaksi agonis terhadap ER-?. Interaksi yang diperoleh dapat menggambarkan bahwa senyawa tersebut mampu memberikan aktivitas estrogenik ketika membentuk ikatan ligan reseptor.
The Culture of Drinking Herbal Medicine in Pregnant Women: A Phenomenological Study Fadlilah, Nazilatul; Shrimarti Rukmini Devy; Mohammad Zainal Fatah; Mangestuti Agil; Ahmaniyah
Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Education Vol. 11 No. 1SI (2023): Jurnal Promkes: The Indonesian Journal of Health Promotion and Health Educat
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jpk.V11.I1SI.2023.63-71

Abstract

Background: Pregnant women who drink herbal medicine can increase the risk of meconium amniotic fluid, and meconium amniotic fluid is a risk factor for asphyxia in newborns. Objectives: Identify three forms of culture in drinking herbal medicine in pregnant women, namely the mother's values and ideas about drinking herbal medicine, herbal drinking activities, and material on the culture of drinking herbal medicine. Methods: This research is a qualitative method with a phenomenological approach. Informants in this study consisted of pregnant women and key informants consisted of families of pregnant women, cadres, ustadzah, midwives, and herbal medicine providers. Results: The cultural forms of drinking herbal medicine include: 1) Values and Ideas. Drinking herbal medicine for pregnant women is still practiced because of their subjective norms and normative beliefs from the surrounding environment. All informants believed that herbal medicine could provide benefits rather than negative effects, and only midwives stated that herbal medicine had negative effects, namely meconium amniotic fluid, and even asphyxia. 2) The activity of drinking herbal medicine. Pregnant women drink herbal medicine from the beginning of pregnancy until delivery. The frequency of taking herbal medicine was various. Religious figures and community leaders have an important role in the culture of drinking herbal medicine. 3) Herbal ingredients. The herbs consumed by each informant were different, there were informants who consumed homemade herbs and bought them at the market. Conclusions: The culture of drinking herbal medicine is still carried out because the local community's belief about the benefits of herbal medicine is still high, and lack of public knowledge about the effects of drinking herbal medicine on pregnant women.
Co-Authors Abdul Hafid B Agnis Pondineka Ria Aditama Ahmaniyah Almay Abidzar Elpasha Amalia, Dilla Anisah Mahardiani Anita Joeliantina Arief Suryadinata Arijanto Jonosewojo Artabah Atik Kurniawati Bambang Wirjatmadi Begum Fauziyah Besin, Valentinus Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma'arif Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Burhan Ma’arif Damaranie Dipahayu Damaranie Dipahayu Damaranie Dipahayu Damaranie Dipahayu, Damaranie Denis Denis Mery Mirza Destiya Argo Pamuji Fihuda Destiya Argo Pamuji Fihuda Dewi Isadiartuti Dilla Amalia Djoko Agus Purwanto Edith Frederika Puruhito, Edith Frederika Esti Hendradi Fadlilah, Nazilatul Faisal Akhmal Muslikh Fatah, Mohammad Zainal Fathia Faza Rahmadanita Fihuda, Destiya A. P. Firdausy, Alif Firman Guhir, Abdul Malik Hajar Sugihantoro Heni Pujiastuti Hening Laswati Hening Laswati Putra Herra Studiawan Husnul Khotimah Imam Subadi, Imam J. A. Pangkahila Jatmiko, Ricky Arie Juni Ekowati Jusak Nugraha Kusnanto Kusnanto Luthfi Achmad Muchlasi M. Artabah Muchlisin M. Bagus Qomaruddin M. Bagus Qomaruddin Ma'arif, Burhan Marta Ika Riyana Maximus M Taek Meilina Ratna Dianti Melanny Ika Sulistyowaty Merryana Adriyani Mohammad Hasan Machfoed Muslikh, Faisal A. Muslim, Menara Nabila Rosa Naesilla Naesilla Ni Made Mertaniasih Notopuro, Paulus Budiono Novia Maulina Nyimas Yusma Aemi Oedojo Soedirham Pramudita Riwanti Purbosari, Ira Purwitasari, Neny Qurnianingsih, Ema Rahmi Annisa Rakhmawati Rakhmawati Resti Perslami, Resti Retno Widyowati Reyhan Rahma Samudra Ria Ramadhani Dwi Atmaja Riyanti, Anisa Eka S.Pd. M Kes I Ketut Sudiana . Sadli Syarifuddin Saidah, Nisfatul L. Saidah, Nisfatul Lailatus Sari, Dewi Perwito Shrimarti Rukmini Devy Siti Maimunah Suko Hardjono Supriyadi Supriyadi Tanaya Jati Dharma Dewi Tutik Sri Wahyuni Widji Soeratri Wirda Anggraini Yunita Satya Pratiwi Yusniasari, Putri Antika Zulvikar Syambani Ulhaq