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Skrining Fitokimia Seduhan Teh Celup Daun Insulin (Tithonia Diversifolia (Hemsl.) A. Gray) dan Daun Teh Hijau (Camellia sinensis L.) Insani, Nurul; Kurnia, Nia Marlina; Buanawati, Vina
Jurnal Ilmiah Kesehatan Delima Vol. 5 No. 1 (2022): Jurnal Ilmiah Kesehatan Delima
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Sekolah Tinggi Ilmu Kesehatan Salsabila Serang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60010/jikd.v5i1.75

Abstract

Flavonoids and saponins that have a lot of potential in the field of pharmacology. Flavonoids and saponins have a lot of potential in the field of pharmacology. The mechanism of action of saponins is by inhibiting GLUT-1 thereby reducing glucose absorption. Flavonoids in diabetes mellitus can avoid sugar absorption, stimulate glucose uptake in peripheral tissues, can also act like insulin by affecting the insulin signaling mechanism. Tannins can trigger glucose and fat metabolism so that the accumulation of these two sources of calories can be avoided, has hypoglycemic activity by increasing glycogenesis. The method is pure experimental method by conducting phytochemical screening of steeping teabags containing insulin leaves and green tea leaves. The results of phytochemical screening of insulin leaf teabags (Tithonia diversifolia (Hemsl.) A. Gray) and green tea leaves (Camellia sinensis L.) showed the presence of secondary metabolites of flavonoids, tannins and saponins.   Flavonoid dan saponin yang banyak berpotensi dalam bidang farmakologi. Mekanisme kerja saponin yaitu dengan menghambat GLUT-1 sehingga menurunkan absorbsi glukosa. Flavonoid pada Diabetes melitus dapat menghindari absorbsi gula, menstimulasi pengambilan glukosa pada jaringan perifer, juga dapat bertindak seperti insulin dengan cara mempengaruhi mekanisme insulin signaling. Tanin dapat memicu metabolisme glukosa dan lemak sehingga timbunan dari kedua sumber kalori ini dapat dihindari, memiliki aktivitas hipoglikemik dengan meningkatkan glikogenesis. Metode penelitian yang digunakan adalah eksperimental murni dengan melakukan skrining fitokimia terhadap seduhan teh celup yang mengandung daun insulin dan daun teh hijau. Hasil skrining fitokimia teh celup daun insulin (Tithonia diversifolia (Hemsl.) A. Gray) dan daun teh hijau (Camellia sinensis L.)  menunjukan adanya senyawa metabolit sekunder flavonoid, tanin dan saponin.
Formulasi Sediaan Pemerah Pipi Sari Kulit Buah Naga Merah (Hylocereus polyrhizus), dan Sari Kunyit (Curcuma domestica L) dalam Bentuk Stick Nurmay Stiani, Sofi; Ayuni, Eka Sirly; Kurnia, Nia Marlina; Yusransyah, Yusransyah
Jurnal Ilmiah Kesehatan Delima Vol. 5 No. 1 (2022): Jurnal Ilmiah Kesehatan Delima
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Sekolah Tinggi Ilmu Kesehatan Salsabila Serang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60010/jikd.v5i1.76

Abstract

The purpose of this study was to make rouge using natural dyes on the skin of red dragon fruit (Hylocereus polyrhizus) and turmeric (Curcuma domestica L). Natural dyes are obtained by smoothing the skin of red dragon fruit (Hylocereus polyrhizus) and turmeric extract (Curcuma domestica L). cheek coloring formula made using a combination of red dragon fruit peel juice (Hylocereus polyrhizus) and turmeric juice (Curcuma domestica L) with concentrations of 10% and 2% (Formula I), 20% and 2.5% (Formula II), 30% and 3% (Formula III). The results of the study with a concentration of 10%: 2%, 20%: 2.5% and 30%: 3% produced a homogeneous blush, aroma, color and good smearing power. pH 4-7, rouge preparations do not cause a reaction (irritation) when applied and the concentration that is preferred by panelists is formula III (30%: 3%). The conclusion of this study is that the combination of red dragon fruit peel juice (Hylocereus polyrhizus) and turmeric juice (Curcuma domestica L) can be used as a natural dye, increasing the concentration of the juice used to increase the dark color pigment in the preparation.   Tujuan penelitian ini adalah untuk membuat pemerah pipi dengan memanfaatkan pewarna alami pada kulit buah naga merah (Hylocereus polyrhizus) dan kunyit (Curcuma domestica L). Pewarna alami diperoleh dengan cara menghaluskan kulit buah naga merah (Hylocereus polyrhizus) dan kunyit (Curcuma domestica L). formula pewarna pipi yang dibuat menggunakan zat kombinasi dari sari kulit buah naga merah (Hylocereus polyrhizus) dan sari kunyit (Curcuma domestica L) dengan konsetrasi 10% dan 2% (Formula I), 20% dan 2,5% (Formula II), 30% dan 3% (Formula III). Hasil penelitian dengan konsentrasi 10% : 2%, 20% : 2,5% dan 30% : 3% menghasilkan pemerah pipi yang homogen, aroma, warna dan daya oles yang baik. pH 4-7, sediaan pemerah pipi tidak menimbulkan reaksi (iritasi) saat dioleskan dan konsentrasi yang banyak disukai panelis adalah formula III dengan konsentrasi 30% : 3%. Kesimpulan dari penelitian ini adalah kombinasi sari kulit buah naga merah (Hylocereus polyrhizus) dan sari kunyit (Curcuma domestica L) dapat digunakan sebagai pewarna alami, semakin tinggi konsentrasi ekstrak yang digunakan maka semakin gelap pigmen warna pada sediaan.
Acmella Uliginosa: Farmakologi, Fitokimia, Toksikologi dan Perkembangan Analog: Review Artikel Kholifah, Eva; Kurnia, Nia Marlina; Insani, Nurul
Jurnal Ilmiah Kesehatan Delima Vol. 4 No. 2 (2022): Jurnal Ilmiah Kesehatan Delima
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Sekolah Tinggi Ilmu Kesehatan Salsabila Serang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60010/jikd.v4i2.82

Abstract

Acmella uliginosa is an important medicinal plant, it is found in tropical and subtropical countries especially Indonesia, India and South America. This plant known as a toothache plant which is usually used to reduce pain associated with toothache. Various extracts and active metabolites from various parts of this plant have beneficial pharmacological activities. Several studies show Acmella Uliginosa has pharmacological activities such as antimicrobial, antipyretic, antioxidant, and anti-inflammatory. This review in detail describes the traditional uses, phytochemicals, pharmacology, toxicology and development of analogues of the active constituents of this plant. This review will help researchers to find scientific information in the future. Acmella Uliginosa adalah tanaman obat penting, ditemukan di negara-negara tropis dan subtropis terutama Indonesia, India dan Amerika Selatan. Tanaman ini dikenal sebagai tanaman sakit gigi yang biasanya digunkan untuk mengurangi rasa sakit yang berhubungan dengan sakit gigi. Bermacam-macam ekstrak dan metabolit aktif dari berbagai bagian tanaman ini memiliki aktivitas farmakologis yang bermanfaat. Beberapa penelitian menyebutkan Acmella Uliginosa memiliki aktivitas farmakologi seperti antimikroba, antipiretik, antioksidan, dan antiinflamasi. Ulasan ini secara rinci menggambarkan penggunaan tradisional, fitokimia, farmakologi, toksikologi dan perkembangan analog dari konstituen aktiv tanaman ini. Review ini akan membantu peneliti untuk mencari informasi ilmiah di masa depan.
In Silico Study of Acmella uliginosa Leaf Compounds Interaction with Human Glucosidase Marlina Kurnia, Nia
Journal Syifa Sciences and Clinical Research Vol 7, No 2 (2025): Volume 7 Edisi 2 2025
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v7i2.30890

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia due to impaired insulin secretion or action. Glucokinase (GK) plays a crucial role in glucose homeostasis and is considered a promising therapeutic target for DM treatment. This study aims to evaluate the in silico interaction between the bioactive compound N-(2-phenylethyl)(2E,6Z,8E)-decatrienamide from Acmella uliginosa (Sw.) and the human GK crystal structure (PDB ID: 1V4S) using Molegro Virtual Docker software. Molecular docking analysis revealed that N-(2-phenylethyl)(2E,6Z,8E)-decatrienamide exhibits a high binding affinity to GK. Physicochemical and pharmacokinetic predictions using pkCSM indicate that this compound has a favorable pharmacokinetic profile, including high intestinal absorption and the ability to cross the blood-brain barrier. These findings suggest that N-(2-phenylethyl)(2E,6Z,8E)-decatrienamide is a promising candidate for the development of natural product-derived antidiabetic drugs. However, further in vitro and in vivo studies are required to validate its biological activity and safety.
Gambaran Kualitas Tidur Mahasiswa Terhadap Intensitas Menonton Drama Korea Fakultas Ilmu Kesehatan Universitas Bina Bangsa Hernawati; Ningsih, Rastia; Esmayanti, Ratna; Kurnia, Nia Marlina; Fiana, Marista
Public Health and Safety International Journal Vol. 5 No. 01 (2025): Public Health and Safety International Journal (PHASIJ)
Publisher : YCMM

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Sleep quality is an important factor in maintaining physical and mental health. The Korean Wave phenomenon is an activity of watching Korean dramas that increases the curiosity of the audience to always want to watch the continuation of the story in each episode or often called chasing broadcasts so that it can cause a person's sleep quality to be poor. The purpose of this study was to determine the picture of the quality of sleep of students regarding the intensity of watching Korean dramas at the Faculty of Health Sciences, Bina Bangsa University. This research method uses a quantitative descriptive method, with a population of 77 people. The sampling technique used cross-sectional with the distribution of the Sleep Quality Index Questionnaire (PSQI) in the form of Google Form and distributed via Whatsapp. The results showed that the majority of students at the Faculty of Health Sciences, Bina Bangsa University had poor sleep quality, as many as 47 respondents (61.0%), while from the results of this number there were 45 respondents (58.4%) who had a high intensity of watching Korean dramas (watching ≥3 hours per title). The conclusion of this study shows that some of the descriptions of the quality of sleep of FIKes UNIBA students regarding the intensity of watching Korean dramas are poor.
The Relationship of Parent Knowledge as Closed Contact about Tuberculosis with Behavior to Prevent Tuberculosis Transmission Maulana, Nova; Handriyanto, Nova Tri; Yuarsa, Tri Agus; Wisnubroto, Agung Prabowo; Esmayanti, Ratna; Kurnia, Nia Marlina
Indonesian Journal of Global Health Research Vol 6 No 4 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i4.3545

Abstract

Pulmonary Tuberculosis is a disease with a very fast transmission rate. The bad impact of tuberculosis infection is death. The increase in pulmonary TB sufferers in Indonesia is caused by unhealthy living behavior and lack of knowledge about the management of precautionary measures for pulmonary tuberculosis transmission. This study aims to determine the relationship between parents' knowledge as close contacts about tuberculosis and behavior to prevent tuberculosis transmission in the Pungkuran Pleret area of Bantul. This quantitative research uses observational research with a cross sectional approach. The population in this study were close contact families of TB sufferers in the Pungkuran Pleret area. The sampling technique used purposive sampling and obtained 30 respondents. Data was collected by checking questionnaires that had been tested as valid and reliable. Meanwhile, the data analysis technique uses the chi-square test. The results of the research can be concluded that the majority of respondents have good knowledge about tuberculosis, 13 respondents (43.34%), but it appears that the majority of respondents still have poor or negative TB prevention behavior, 20 respondents (66.67%). The most cross tabulation results were that there were 10 respondents (33.33%) with the analysis having good knowledge about tuberculosis and having behaved positively in preventing TB. A total of 10 respondents (33.33%) with analysis had insufficient knowledge about tuberculosis and preventive behavior in the negative category. However, in total, the majority of close contact parent respondents in the Pungkuran Pleret area have behavior that is still in the negative category in preventing TB. The results of the chi-square analysis test showed a p-value of 0.000, which means there is a relationship between parents' knowledge as close contacts about tuberculosis and behavior to prevent tuberculosis transmission in the Pungkuran Pleret area.
Factors associated with understanding and perineal wound care behavior of postpartum mothers in Cikeusik district, Pandeglang regency Kurnia, Nia Marlina; Rahayu, Antika Maulida; Shobah, Afifah Nur
Science Midwifery Vol 12 No 2 (2024): June: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i2.1538

Abstract

Maternal deaths after childbirth occur when perineal wounds are common in women after childbirth, either vaginally or by caesarean section. This wound can cause pain, discomfort, and potentially lead to infection if not treated properly. Proper care of perineal wounds in accordance with the recommendations of health workers is very important to accelerate the healing process and prevent complications. The purpose of this study was to determine the relationship between factors with knowledge and behavior of perineal wound care in postpartum women in Cikeusik District Pandeglang-Banten. This study used quantitative research with a cross sectional design based on analysis using chi square statistical test >0.05, known p value 0.00 for variable debriefing, p value 0.01 for variable parity and p value 0.02 for variable age. Conclusion There is a significant relationship between age, parity and debriefing factors with understanding and behavior of perineal wound care.
Pengendalian Komplikasi Dibetes Melitus Melalui Program Penataan Diet Pada Penderita Diabetes Melitus Maulana, Nova; Ratna Esmayanti; Nia Marlina Kurnia; Rania Permata Rifayanti; Agung Wisnubroto; Popy Ramadhani
Media Pengabdian Kesehatan Indonesia Vol. 1 No. 1 (2024): JANUARY
Publisher : Kabar Gizi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62358/p40b4x39

Abstract

Diabetes melitus menjadi penyakit metabolik kronis yang dapat menyebabkan kerusakan serius pada jantung, pembuluh darah, mata, ginjal, dan saraf. Pola hidup instan menjadi salah satu pemicu tingginya kadar glukosa darah tubuh. Pengabdian kepada masyarakat ini dilakukan balai RT Kp. Cimeong, Ds. Sukamenak, RT 08. Kec. Baros, Kab. Serang, Banten mulai November 2023 hingga Januari 2024. Program kegiatan ini dirancang sebagai upaya penataan diet menu sehari-hari untuk individu dengan diabetes mellitus. Metode yang digunakan antara lain screening diabetes melitus, penyuluhan, dan diskusi tentang diet atau pola makan yang dikonsumsi agar sesuai dengan kebutuhannya. Program ini dilaksanakan selama tiga bulan, dalam kegiatan ini dilakukan 4 kali kunjungan. Hasil pengabdian menunjukkan telah terlaksananya survey screening pengecekkan glukosa darah pada seluruh warga yang hadir, edukasi penataan diet dibetes melitus, monitoring kembali glukosa darah dan dilakukan evaluasi pola konsumsi yang dilakukan selama dirumah serta terlaksananya evaluasi proses hasil kegiatan yang dilakukan. Kesimpulan dalam kegiatan dengan tema pengendalian komplikasi dibetes melitus melalui program penataan diet pada penderita diabetes melitus berjalan dengan sukses.
SOSIALISASI TATA CARA MENCUCI TANGAN YANG BENAR DI SDN SERANG ILIR KECAMATAN CIWANDAN Riyadi, Muhammad Aditya Wiguna; Kurnia, Nia Marlina; Esmayanti, Ratna; Zakky, Betha Muhammad; Wulandari, Erina; Rohmatillah, Fevie; Hasibuan, Garnis Ramitha; Misadiwana, Imoni; Kurniazaki, Muhammad Khafidin; Irfansyah, Reinanda Aulia; Rahman, Tubagus Irsyad Rizkia; Firdaus, Hifdy
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 4 (2024): Volume 5 No. 4 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i4.33826

Abstract

Kebiasaan mencuci tangan dengan benar merupakan salah satu cara paling efektif untuk mencegah penyebaran penyakit, terutama di lingkungan sekolah. Sosialisasi tata cara mencuci tangan di SDN Serang Ilir, Kecamatan Ciwandan, bertujuan untuk meningkatkan kesadaran dan pemahaman siswa mengenai pentingnya menjaga kebersihan tangan sebagai langkah pencegahan terhadap infeksi. Kegiatan sosialisasi ini melibatkan siswa, guru, dan tenaga pendidik, menggunakan pendekatan interaktif seperti demonstrasi langsung, video edukasi, dan permainan edukatif. Hasil dari sosialisasi menunjukkan peningkatan pemahaman dan keterampilan siswa dalam mencuci tangan sesuai dengan prosedur yang benar. Selain itu, kegiatan ini juga berhasil membangun kesadaran kolektif di kalangan siswa mengenai pentingnya kebersihan tangan untuk kesehatan diri sendiri dan orang lain. Dengan demikian, sosialisasi ini diharapkan dapat berkontribusi dalam menciptakan lingkungan sekolah yang lebih sehat dan bebas dari penyakit.
PENINGKATAN KESADARAN GIZI DAN KESEHATAN MASYARAKAT MELALUI PROGRAM PENYULUHAN TERPADU DI SDN 01 KADUBEUREUM DAN SDN PALEUH SINDANGHEULA, KECAMATAN PABUARAN Andika Putra, Deri; Maulana, Nova; Marlina Kurnia, Nia; Tri Handriyanto, Nova; Salma Yunia Rachmah, Ade
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 6, No 9 (2023): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v6i9.3062-3073

Abstract

Penelitian ini membahas efektivitas kegiatan "Kesadaran Gizi dan Kesehatan Masyarakat" melalui penyuluhan interaktif di SDN 01 Desa Kadubeureum dan SDN Paleuh Sindangheula. Metode kuis interaktif dan pemberian hadiah digunakan untuk meningkatkan pemahaman siswa tentang gizi seimbang dan kesehatan masyarakat. Hasil menunjukkan partisipasi aktif siswa dan peningkatan pemahaman yang signifikan. Kerjasama dengan mahasiswa, guru SD, dan RS Sari Asih memberikan dukungan yang penting dalam mencapai tujuan pendidikan gizi yang efektif.