Articles
<![CDATA[Efek Pemberian Jus Buah Jambi Biji Daging Merah (Psidium guajava L.) Terhadap Aktivitas Dan Kapasitas Fagositosis Pada Mencit Putih Jantan ]]>
<![CDATA[Yufri Aldi]]>;
<![CDATA[Widya Nengsih]]>;
<![CDATA[Zet Rizal]]>
<![CDATA[ Jurnal Farmasi Higea Vol 4, No 2 (2012) ]]>
Publisher : <![CDATA[STIFARM Padang ]]>
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DOI: 10.52689/higea.v4i2.67
<![CDATA[Reasearch about the effect of feeding guava red meat juice (Psidium guajava L.) on the activity and capacity of peritoneal macrophage phagocytic of white males mice has been done. The test sample is given orally for 7 days with a dose of 0.13 mL/20g BB, 0.26 mL/20g BB and 0.52 mL/20g BB, while the control group was given only distilled water. On the eighth day the bacteria Staphylococcus aureus was injected to mice intraperitonially. Result of this experiment showed that guava juice can increased activity and capacity of macrophage (P<0.05).Psidium guava L ,phagocyticed, white mice]]>
<![CDATA[Aktivitas Imunomodulator dari Ekstrak Etanol Meniran (Phyllanthus niruri Linn.) terhadap Ayam Broiler ]]>
<![CDATA[Yufri Aldi]]>;
<![CDATA[Yahdian Rasyadi]]>;
<![CDATA[Dian Handayani]]>
<![CDATA[ Jurnal Sains Farmasi & Klinis Vol 1, No 1 (2014): J Sains Farm Klin 1(1), November 2014 ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Andalas ]]>
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DOI: 10.29208/jsfk.2014.1.1.21
<![CDATA[Ayam Broiler sangat rentan terhadap penyakit-penyakit yang disebabkan oleh bakteri dan virus. Oleh karena itu untuk mengatasi masalah ini kita dapat menggunakan pengobatan alternatif dengan pemberian senyawa imunostimulan yang dapat mencegah penyakit pada ayam broiler. Salah satu tanaman yang dapat meningkatkan sistem kekebalan tubuh adalah meniran. Studi efek imunomodulator dari ekstrak etanol meniran (Phyllanthus niruri Linn.) telah dilakukan pada ayam broiler dengan metode bersihan karbon. Ekstrak diberikan secara oral dengan dosis 10; 30; 100; 300 mg/kg BB dan larutan 0,5% NaCMC sebagai kontrol serta suspensi Stimuno® forte 13,5 mg/kg BB sebagai pembanding selama 6 hari. Data indeks fagositosis dianalisis secara statistik dengan ANOVA dua arah dilanjutkan dengan uji Duncan. Peningkatan indeks fagositosis menunjukkan bahwa efek dari setiap dosis dengan kontrol negatif berbeda signifikan (P <0,05). Indeks fagositosis tertinggi diperoleh dari dosis 300 mg/kg BB. Data tentang peningkatan berat relatif limpa dan peningkatan sel limfosit darah dianalisis dengan ANOVA satu arah dilanjutkan dengan uji Duncan. Peningkatan berat limpa relatif dan peningkatan sel limfosit darah menunjukkan efek dari masing-masing dosis untuk kontrol negatif berbeda signifikan (P<0,05). Hasil penelitian menunjukkan bahwa ekstrak etanol meniran aktif sebagai imunostimulan untuk ayam broiler.]]>
<![CDATA[Analisis Pelayanan Resep Konvensional dan Elektronik serta Pengaruhnya terhadap Kualitas Pelayanan Kefarmasian di RSUD M. Natsir Solok Indonesia ]]>
<![CDATA[Adrizal Adrizal]]>;
<![CDATA[Fatma Sriwahyuni]]>;
<![CDATA[Yufri Aldi]]>
<![CDATA[ Jurnal Sains Farmasi & Klinis Vol 6, No 3 (2019): J Sains Farm Klin 6(3), Desember 2019 ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Andalas ]]>
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DOI: 10.25077/jsfk.6.3.195-199.2019
<![CDATA[Rumah Sakit wajib memberikan pelayanan yang berkualitas sesuai dengan Standar Pelayanan Minimal (SPM) yang telah di tetapkan. Upaya untuk meningkatkan kualitas pelayanan kefarmasian di rumah sakit dapat dilakukan dengan penerapan peresepan elektronik. Penelitian bertujuan untuk mengetahui perbedaan kualitas pelayanan kefarmasian antara peresepan konvensional dan peresepan elektronik. Desain penelitian adalah observasional analitik dengan rancangan cross sectional study. Sampel berjumlah 431 resep diambil dengan teknik random sampling. Uji statistik pada variabel waktu tunggu dan kepuasan pasien yaitu uji t–independen sedangkan variabel kesalahan pemberian obat dan kesesuaian resep dengan formularium digunakan uji chi_square dengan tingkat kemaknaan 0,05. Hasil penelitian menunjukan terdapat perbedaan waktu tunggu (p value:0,000), kepuasan pasien (p value:0,000) dan kesesuaian resep dengan formularium (p value:0,000) antara peresepan elektronik dengan peresepan konvensional. Namun tidak terdapat perbedaan kejadian kesalahan pemberian obat antara peresepan elektronik dengan peresepan konvensional (p value:0,063). Penelitian ini menunjukkan bahwa kualitas pelayanan kefarmasian pada peresepan elektronik lebih baik dibandingkan dengan peresepan konvensional. Pimpinan dan manajerial RSUD M.Natsir hendaknya mengimplementasikan peresepan elektronik ini pada instalasi rawat jalan dan rawat inap sehingga kualitas pelayanan kefarmasian dapat ditingkatkan.]]>
<![CDATA[Identifikasi Type Human Papillomavirus (HPV) pada Penderita Kanker Serviks ]]>
<![CDATA[Marlina Marlina]]>;
<![CDATA[Yufri Aldi]]>;
<![CDATA[Andani Eka Putra]]>;
<![CDATA[Densi Selpia Sopianti]]>;
<![CDATA[Dewi Gulyla Hari]]>;
<![CDATA[Arfiandi Arfiandi]]>;
<![CDATA[Akmal Djamaan]]>;
<![CDATA[Rustini Rustini]]>
<![CDATA[ Jurnal Sains Farmasi & Klinis Vol 3, No 1 (2016): J Sains Farm Klin 3(1), November 2016 ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Andalas ]]>
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DOI: 10.29208/jsfk.2016.3.1.100
<![CDATA[Human Papillomavirus (HPV) is the most significant risk factor for the cause of cervical cancer. The purpose of this study for identification of HPV types 16, 18, 31, 33, 45 and 52 in cervical cancer patients. HPV is a row of high-risk HPV types that can cause cervical cancer. Total sample of 78 diisolat DNA derived from FFPE, cervical smears and cervical cancer fresh tissue obtained from Dr. Dr. M. Djamil, Padang and hospitals. Arifin Achmad, Pekanbaru. HPV DNA detection is done by using Polymerase Chain Reaction (PCR) using universal primers GP5 +/6 +. HPV types were identified by PCR with specific primers. Total sample types obtained with concentrations varying between 0.9 to 645 ng / ml with purity DNA in accordance with the specified purity for PCR amplification. The results of the study of 78 patients with cervical cancer samples, 42 samples (54%) identified HPV DNA. HPV type 18 is more dominant and followed by HPV type 16 as compared to the other types, namely the percentage of 40.4% and 28.5%. HPV type 45 (7.1%), HPV type 52 (2.3%) and HPV 31 and HPV type 33 was not detected.]]>
<![CDATA[Identifikasi Gen E7 Isolat Human Papillomavirus Tipe 18 (HPV18) dari Penderita Kanker Serviks ]]>
<![CDATA[Arfiandi Arfiandi]]>;
<![CDATA[Densi Selpia Sopianti]]>;
<![CDATA[Dewi Gulyla Hari]]>;
<![CDATA[Marlina Marlina]]>;
<![CDATA[Yufri Aldi]]>;
<![CDATA[Andani Eka Putra]]>;
<![CDATA[Akmal Djamaan]]>;
<![CDATA[Rustini Rustini]]>
<![CDATA[ Jurnal Sains Farmasi & Klinis Vol 3, No 1 (2016): J Sains Farm Klin 3(1), November 2016 ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Andalas ]]>
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DOI: 10.29208/jsfk.2016.3.1.95
<![CDATA[Gen E7 HPV18 merupakan salah satu onkoprotein yang selalu diekspresikan oleh HPV pada sel yang terinfeksi. Infeksi persisten oleh Human papillomavirus (HPV) beresiko tinggi adalah faktor etiologi utama untuk kanker serviks dan ekspresi Onkoprotein HPV E7 disarankan untuk menjadi penanda potensial untuk perkembangan tumor. E7 akan mempengaruhi aktivitas pRB supresor tumor serta mengikat dan mengaktifkan kompleks cyclin sehingga dapat menimbulkan kanker serviks. Dalam penelitian ini akan dilakukan identifikasi terhadap Gen E7 isolat HPV18 dari penderita kanker serviks yang berasal dari RSUP M. Jamil Padang, Sumatera Barat dan RSUD Arifin Ahmad, Pekan Baru, Riau. Proses identifikasi dilakukan dengan metode Polymerase Chain Reaction (PCR) menggunakan primer spesifik untuk gen E7 HPV18. Dari lima belas isolat HPV18 yang diamplifikasi dengan primer spesifik gen E7 HPV18, didapatkan sepuluh sampel positif teridentifikasi gen E7 (66,6%) sedangkan lima sampel lainnya tidak teridentifikasi. Infeksi kanker pada penderita kanker serviks yang berasal dari RSUP. M. Jamil, Padang dan RSUD. Arifin Ahmad, Pekan Baru, Riau sebagian besar disebabkan oleh gen E7 HPV18 sehingga hal ini bisa dijadikan penanda potensial untuk perkembangan tumor bagi penderita kanker serviks di Sumatera Barat dan Riau pada khususnya serta di Indonesia pada umumnya.]]>
<![CDATA[Pengaruh Dispersi Padat Irbesartan-Poloxamer 188 Terhadap Tekanan Darah dan Kadar Nitric Oxide (NO) Pada Tikus Putih Jantan Hipertensi ]]>
<![CDATA[Fifi Harmely]]>;
<![CDATA[Ellyza Nasrul]]>;
<![CDATA[Salman Umar]]>;
<![CDATA[Erizal Zaini]]>;
<![CDATA[Yufri Aldi]]>
<![CDATA[ Jurnal Sains Farmasi & Klinis Vol 5, No 2 (2018): J Sains Farm Klin 5(2), Agustus 2018 ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Andalas ]]>
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DOI: 10.25077/jsfk.5.2.88-93.2018
<![CDATA[A research on formulation of edible film from basil leaves extract as mouth freshener has been done. The extract of basil leaves were used in various concentrations which are 2.5%, 5% and 7.5%. The products were evaluated for some parameters such as organoleptic, friability, drying shrinkage, pH, thickness, flavonoid contents and respondents preference. The results of evaluation showed that edible filmsfrom basil leaves extract meet requirements as required by Standard Nasional Indonesia (SNI) and have such quality as product in the market. Statistical analysis using Kruskal Wallis test showed that respondents preferred for the F0 formulation in term of their appearance and taste while as mouth freshener, respondents preferred the F3 formulation.]]>
<![CDATA[Aktivitas Ekstrak Daun Suji (Dracaena angustifolia Roxb.) sebagai Antianafilaksis Kutan Aktif pada Mencit Putih Jantan ]]>
<![CDATA[Yufri Aldi]]>;
<![CDATA[Muhammad Syafrudin]]>;
<![CDATA[Elisma Elisma]]>
<![CDATA[ Jurnal Sains Farmasi & Klinis Vol 1, No 2 (2015): J Sains Farm Klin 1(2), Mei 2015 ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Andalas ]]>
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DOI: 10.29208/jsfk.2015.1.2.31
<![CDATA[An assay of the active cutaneous anti anaphylactic of the ethanolic extract of the Dracaena angustifolia Roxb. On male white mice has been studied. The assay was done by giving three different doses (100,300, 900 mg per/kg bw). Allergic reaction was induced by giving egg’s albumin as antigen. The anti anaphylactic effect was determined by measurement of the pro long of occurrence time, the dereased in diameter and the color intensity of the blue bump formed by using blue evan’s solution as indicator which was given intravenously. Result indicated the ethanolic extract of Dracaena angustifolia Roxb. (100, 300, 900 mg/kg bw) had significant effect for each dose (p<0.01). The dose of 900 mg per kg body weight showed best effect.]]>
<![CDATA[UJI ANTI INFLAMASI SECARA TOPIKAL EKSTRAK ETANOL UMBI SARANG SEMUT (Myrmecodia tuberosa Jack) PADA MENCIT PUTIH JANTAN ]]>
<![CDATA[Muhammad Islamoyo]]>;
<![CDATA[Yufri Aldi]]>;
<![CDATA[Surya Nelis]]>
<![CDATA[ Andalas Dental Journal Vol 5 No 2 (2017): Andalas Dental Journal ]]>
Publisher : <![CDATA[Faculty of Dentistry Universitas Andalas ]]>
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DOI: 10.25077/andalas dent. j..v5i2.77
<![CDATA[Inflammation is a tissue response towards damaging physical or chemical stimulations. One local sign of inflammation is edema (tumor). Usage of natural herbal medicine has become an alternative way to prevent inflammation. The extract of umbi sarang semut (Myrmecodia tuberosa Jack) has anti-inflammation, anti-bacterial and antioxidant properties. This study is to determine the anti-inflammation effect of the topical application of Myrmecodia tuberosa Jack ethanol extract. This study used 28 white male rats previously induced with carragenin 2% b/v 0,5ml and divided into 4 treatment groups. Groups 1,2 dan 3 were given the ethanol extract with a concentration of 0,5 %; 1%; 2% respectively after induction and on 24, 48 and 72 hours after the first application. Group 4 was the untreated control group. Each treatment group were extracted for their inflammation exudate fluid from their backs using a 1 ml syringe. Edema fluid volume was measured. The results showed a decrease of edema fluid volume on all treatment groups. Statistical data analysis showed a significant difference between group 2 and the negative control; also between group 3 and the negative control. In conclusion, the topical ethanol extract of Myrmecodia tuberosa Jack can reduce inflammation reactions. Keywords: Myrmecodia tuberosa Jack, anti-inflammation, topical, edema fluid volume]]>
<![CDATA[DAYA HAMBAT JUS APEL MANALAGI (MALUS SYLVESTRIS) TERHADAP PERTUMBUHAN BAKTERI PORPHYROMONAS GINGIVALIS SECARA IN-VITRO ]]>
<![CDATA[Enda Markus Aginta Sembiring]]>;
<![CDATA[Yufri Aldi]]>;
<![CDATA[Susi Susi]]>
<![CDATA[ Andalas Dental Journal Vol 6 No 2 (2018): Andalas Dental Journal ]]>
Publisher : <![CDATA[Faculty of Dentistry Universitas Andalas ]]>
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DOI: 10.25077/adj.v6i2.122
<![CDATA[Background: Periodontitis are one of teeth and mouth disease with prevalence is 50% of adult. Periodontitis is an inflammatory condition that cause damage to connective tissue and alveolar bone. Porphyromonas ginggivalis is one of anaerob gram-negative bacteria that cause periodontitis, these bacteria can withstand host’s defenses mechanism by utilizing a virulence factor panel that cause derived innate immune and inflamatory responses. Apple Manalagi or known as apple Malang is one of the herbal plants in Indonesia. Some studies represented inhibitory effect for bacteria from its substance. Objective: The objective of this study were to determine inhibitory effect of apple manalagi (Malus sylvestris) for Porphyromonas ginggivalis. Method: Experimental laboratory. In this study Apple Manalagi will be Juiced, Juice Apple Manalagi will divide by 4 concentrate 25%, 50%, 75% and 100%. This study use diluusion method, juice apple Manalagi will aplicated to 5 samples agar MHA for 5 times. The inhibitory effect will calculated with sliding calipers, and then data will process with one way anova. Result: The result didn’t show any inhibision zone in MHA to Porphyromonas ginggivalis so data analysis cann’t be done. Conclusion: Apple Manalagi doesn’t have inhibitory effect for Porphyromonas ginggivalis.]]>
<![CDATA[Bijak dalam Menggunakan Antibiotika di Nagari Padang Laweh ]]>
<![CDATA[Dwisari Dillasamola]]>;
<![CDATA[Hansen Nasif]]>;
<![CDATA[Yufri Aldi]]>
<![CDATA[ Warta Pengabdian Andalas Vol 29 No 4 (2022) ]]>
Publisher : <![CDATA[Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas ]]>
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DOI: 10.25077/jwa.29.4.382-387.2022
<![CDATA[The high use of antibiotics inappropriately among the community today causes the problem of antibiotic resistance. Antibiotic resistance occurs when microorganisms have the ability to withstand the effects of an antibiotic drug. This can cause losses in terms of health, economy, and public health. To prevent the inappropriate use of antibiotics, education is carried out on how to use antibiotics wisely, which is good and right. The counseling method in this service activity is the lecture method where this method is good for targets with high and low education, especially the general public. The results that this service was that the community looks enthusiastic about carrying out this community service activity. The conclusion of this activity is that education and counseling can increase public knowledge about the use of antibiotics.]]>
