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All Journal Jurnal Teknologi Industri Pertanian Jurnal Sain Veteriner International Journal of Renewable Energy Development Tengkawang : Jurnal Ilmu Kehutanan BIOTROPIA - The Southeast Asian Journal of Tropical Biology Indonesian Journal of Forestry Research Jurnal Penelitian Hasil Hutan Jurnal Penelitian Hutan Tanaman Jurnal Riset Industri JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) BERITA BIOLOGI Indonesian Journal of Chemistry Jurnal Ilmu dan Teknologi Kayu Tropis Teknologi Indonesia Jurnal Penelitian Hasil Hutan Wood Research Journal : Journal of Indonesian Wood Research Society Wood Research Journal : Journal of Indonesian Wood Research Society Jurnal Sylva Lestari Makara Journal of Technology Jurnal Ilmu Kehutanan Jurnal Ilmu Kehutanan International Journal of Renewable Energy Development Jurnal Penelitian Hasil Hutan
Wasrin Syafii
Departemen Hasil Hutan, Fakultas Kehutanan, Institut Pertanian Bogor Kampus IPB Darmaga, Bogor 16680
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Public Health Veterinary

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Journal : Jurnal Sylva Lestari

 1 
Anti-Termite Activity of Melia azedarach Extracts Yanico Hadi Prayogo; Romi Irka Putra; Izza Firdausi Hadiyanto; Evie Nihayah; Wasrin Syafii; Rita Kartika Sari; Irmanida Batubara
Jurnal Sylva Lestari Vol. 10 No. 1 (2022): January
Publisher : Department of Forestry, Faculty of Agriculture, University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jsl.v10i1.549

Abstract

Natural preservatives have been widely considered as non-synthetic materials that can prevent the biodegradation of wood due to subterranean termite attacks, namely Coptotermes curvignathus. Melia azedarach is a fast-growing species that has been widely studied for its antifeedant compounds and shows good potential to be developed as a biopesticide, especially as an anti-termite. This study aimed to identify the termicide and antifeedant properties of the wood, leaves, and bark extracts of Melia azedarach against subterranean termites and identify their bioactive compounds. The acetone extract from the three parts of the tree was fractionated. The most active fractions were selected from each part based on the percentage of termite mortality and antifeedant activity and analyzed for its bioactive compounds by pyrolysis GCMS. The ethyl acetate fraction of Melia azedarach bark exhibited strong toxic properties compared to other fractions. In the leaf section, the diethyl ether fraction showed the best termite repellent (antifeedant) properties. The anti-termite properties influenced phenolic compounds and organic acid that dominated the bark ethyl acetate fraction and leaf diethyl ether fraction. These findings show the great potential of bioactive compounds from biomaterials to be developed as a promising biopesticide. Keywords: anti-termite, bioactive compound, Melia azedarach, natural preservative
Ultrasound-Assisted Extraction of Antimalarial Compounds from the Bidara Laut (Strychnos ligustrina) Heartwood Sri Familasari; Rita Kartika Sari; Wasrin Syafii; Anne Carolina; Umi Cahyaningsih; Siti Sa'diah
Jurnal Sylva Lestari Vol. 11 No. 3 (2023): September
Publisher : Department of Forestry, Faculty of Agriculture, University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jsl.v11i3.682

Abstract

The aqueous wood extract of bidara laut (Strychnos ligustrina) from maceration demonstrated the greatest antimalarial activity against Plasmodium falciparum strain 3D7. However, this method has several limitations, including a lengthy extraction time, which allows for microorganism contamination. The aim of this study was to quantify the yield, evaluate the antimalarial effectiveness of the P. falciparum growth in-vitro, and analyze the aqueous bidara laut heartwood extracts phytochemical composition from the two different extraction methods,  namely the method of maceration extraction for 24 hours and the ultrasound-assisted extraction (UAE) for 30 (UAE30), 45 (UAE45), and 60 (UAE60) minutes. The bidara laut heartwood extract from the UAE60 method had relatively similar yield and antimalarial activity with the bidara laut heartwood extract from the UAE45 method. However, these extracts had higher yield and antimalarial activity than the extracts from the maceration and the UAE30 methods. The results of LC-MS/MS analysis revealed that the main compounds in the UAE45 and UAE60 extracts were strychnine, quinaprilat, and 3,4-bis-cyclobut-3-ene-1,2-dione, which has potent antimalarial properties. Keywords: antimalarial activity, Plasmodium falciparum, quinaprilat, strychnine, Strychnos ligustrina
Chemical Constituent of Acacia auriculiformis Wood Extractives and Their Antioxidant Activity Yanico Hadi Prayogo; Irmanida Batubara; Rita Kartika Sari; Saat Egra; Kosei Yamauchi; Tohru Mitsunaga; Wasrin Syafii
Jurnal Sylva Lestari Vol. 11 No. 3 (2023): September
Publisher : Department of Forestry, Faculty of Agriculture, University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jsl.v11i3.753

Abstract

Acacia auriculiformis showed good potential to be developed as a raw material for bioactive compounds. The heartwood of A. auriculiformis is still rarely explored. The purpose of this study was to identify the bioactive components of the heartwood. Six compounds were identified from the heartwood through nuclear magnetic resonance and mass spectroscopy, namely the C-3,4',7,8 hydroxyl substituted flavonoids and chalcone. Two methylated teracacidins and chalcone-like teracacidin were identified for the first time in the A. auriculiformis heartwood, along with three known compounds. These compounds showed good radical scavenging and reduction activity, compared to crude extract and ascorbic acid, using three different antioxidant assays. The molecular structure-dependent activity was observed to affect the trend of the different antioxidant activities. This finding shows good potential for further development of plant parts of A. auriculiformis from Indonesia as new raw materials for medicines. Keywords: Acacia auriculiformis, antioxidant, chalcone, flavonoid, heartwood
Antidiabetic Activities of Agarwood (Aquilaria malaccensis) Leaf Extracts via Enhanced Insulin Secretion in BRIN-BD11 Pancreatic Beta-Cells Prayogo, Yanico Hadi; Sari, Rita Kartika; Hamidi, Zikri; Syafii, Wasrin; Harlina, Eva; Prasetyo, Bayu Febram
Jurnal Sylva Lestari Vol. 13 No. 3 (2025): September
Publisher : Department of Forestry, Faculty of Agriculture, University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jsl.v13i3.1197

Abstract

Agarwood leaves (Aquilaria malaccensis), a non-timber forest products, shows significant potential as a source of antidiabetic compounds. This study aims to evaluate the antidiabetic activity of agarwood leaves and their cytotoxicity on pancreatic beta-cells, as well as predict their compound bioactivity through an in silico approach. The leaves were extracted using ethanol, water, and a mixture of ethanol–water with the assistance of ultrasound irradiation. The extracts were then tested in vitro for their antidiabetic potential by assessing their ability to inhibit the alpha-glucosidase enzyme and their effect on insulin secretion, as well as their cytotoxicity on BRIN-BD11 pancreatic beta-cells. The phytocompounds in the extract were identified using liquid chromatography-mass spectrometry, and their binding behavior was studied by in silico molecular docking. Among the three, the ethanol–water extract showed the highest extraction yield. Cytotoxicity assays revealed that the ethanol–water extract was cytotoxic at high concentrations (1000 µg/mL), but safe at lower concentrations. The alpha-glucosidase inhibition was relatively weak. Nevertheless, the extracts significantly stimulated insulin secretion in BRIN-BD11 cells up to fivefold compared to untreated cells. In silico studies indicated that xanthone glycoside, flavonoid glycoside, and coumarin compounds exhibit strong binding affinities to multiple insulin-secretion-related proteins. These findings suggest that agarwood leaf extract, particularly ethanol–water extract, possesses promising antidiabetic activity through an insulinotropic mechanism. Keywords: agarwood, alpha-glucosidase, insulinotropic, molecular docking
Co-Authors Abdul Aziz Darwis Achmad Achmad Achmad Achmad Adesna Fatrawana Adesna Fatrawana Akhiruddin Maddu Akhirudin Maddu Akhirudin Maddu Akhirudin Maddu Amril Aman Anak Agung Istri Sri Wiadnyani Ani Suryani Anne Carolina Bambang Prasetya Bambang Prasetya Bambang Prasetya Bayu Febram Prasetyo Bintang C. H. Simangunsong Buchari Buchari Buchari Buchari Deded Sarip Nawawi Deded Sarip Nawawi Denny Irawati Desi Melianti Dewi R Agungpriyono E Gumbira Sa, E Gumbira Eka Novriyanti Eka Novriyanti Eko Budi Santoso Eko S Pribadi Elis Nina Herliyana ENDANG SUHENDANG Erdy Santosa Erdy Santosa Eva Harlina Evie Nihayah Fabianus Ranta Fahriya Puspita Sari Faizatul FALAH Fathul Yusro Fauzi Febrianto Gunawan Pasaribu Gunawan Pasaribu Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustan Pari Gustini Syahbirin Hamidi, Zikri Herman Siruru Herman Siruru Hikma Yanti Hiroyuki Yamamoto Husni Y Rosadi, Husni Y I MADE ARTIKA I Nyoman Jaya Wistara IGK Tapa Darma Illah Sailah Imam Wahyudi Indrawan, Imam Wahyudi Irmanida Batubara Irnayuli R. Sitepu Irnayuli R. Sitepu Iskandar Z Siregar Istie Rahayu Izza Firdausi Hadiyanto Jemi, Renhart Juliasman Juliasman Karliati, Tati Khaswar Syamsu Kosei Yamauchi Kurnia Sofyan Kurnia Sofyan Kurnia Sofyan Laela N. Anisah Laela Nur Anisah Latifah K. Darusman Latifah K. Darusman Lucky Risanto M. Daud Maggy T Suhartono Maggy T Suhartono Maman Turjaman Maman Turjaman Maya Ismayati Mody Lempang Mody Lempang Mody Lempang Mody Lempang Muflihati Muflihati Muhammad Adly Rahandi Lubis Muhammad Fadli Muhammad Hanafi Nissa Nurfajrin Solihat Norman Razief Azwar Nugraha, Arifin Budiman Nur Adi Saputra Nur Adi Saputra Nur Azizah Prayogo, Yanico Hadi Pudja Mardi utomo Pudja Mardi utomo Purwoko, Agus Rahmi Mauladdini Rahmi Mauladdini Renhart Jemi Rita K Sari Rita Kartika Sari Romi Irka Putra S Heris Anita Saat Egra Santiyo Wibowo Santiyo Wibowo Santiyo Wibowo Saptadi DARMAWAN Saptadi Darmawan Saptadi Darmawan Simon Taka Nuhamara Simon Taka Nuhamara Siruru, Herman Siti Maemunah Siti Sa'diah Siti Sa'diah Soetrisno Hadi Soetrisno Hadi Sri Familasari Suminar A Achmadi Suminar S Achmadi Syamsul Arifin Tohru Mitsunaga Umi Cahyaningsih Widya FATRIASARI Widya Fatriasari Widya Fatriasari Widya FATRIASARI Yanico Hadi Prayogo Yanotama T Laksana Yanti Hikma Yusup AMIN