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Systematic Journal Review: Mechanical Durability Of L-PRF Organic Material At Body Temperature During The Wound Healing Phase (14 Days) Of Tympanic Membrane Perforation And Myringoplasty Surgery Antonius Christanto; Risya Cilmiaty; Made Setiamika; Ratih Dewi Yudhani; Paramasari Dirgahayu; Eti Poncorini Pamungkasari; Ida Nurwati
PROMOTOR Vol. 9 No. 1 (2026): FEBRUARI
Publisher : Universitas Ibn Khaldun Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/pro.v9i1.1741

Abstract

The purpose of this study is to evaluate the viability and structural stability of L-PRF at 37°C over 14 days. It aims to determine its sustained growth factor release and potential effectiveness in regenerative clinical applications. This research employed a Systematic Journal Review (SJR) approach, surveying articles from databases such as PubMed, Scopus, and Google Scholar using specific keywords related to L-PRF. A total of 25 articles meeting the inclusion criteria were filtered for analysis. Furthermore, common experimental methods described in the literature include the preparation of L-PRF via blood centrifugation and viability testing over 14 days at 37°C, encompassing analysis of microscopic structure, mechanical properties, and biochemical and biological activities. Literature analysis indicates that L-PRF is an effective autologous biomaterial for regenerative applications, capable of continuously releasing growth factors such as PDGF, TGF-β, VEGF, and IGF for up to 14 days at body temperature. Cell viability within the fibrin matrix is maintained, positioning L-PRF as a promising active biological scaffold for accelerating tissue healing. Although challenges such as matrix degradation persist, modification strategies and optimized centrifugation protocols can enhance the effectiveness and durability of L-PRF in clinical applications.
Effects of Chrononutrition, Emotional Eating, and Self-Control on Blood Pressure among Hypertensive Patients Meryance Sinaga; Eti Poncorini Pamungkasari; Tri Rejeki Andayani
Indonesian Journal of Global Health Research Vol. 8 No. 5 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i5.2226

Abstract

Hypertension remains a major global health challenge, with pharmacological treatment as the mainstay of management. However, modifiable behavioural and chronobiological factors such as chrononutrition, emotional eating, and self-control are increasingly recognised as important contributors to blood pressure regulation. Despite this recognition, these three factors have not been examined together in hypertensive populations. Understanding their combined relationships is important to support the development of more comprehensive behavioural interventions for hypertension management. Therefore, this study aimed to simultaneously examine the relationships between chrononutrition, emotional eating, and self-control with blood pressure among hypertensive patients attending primary health centres in Banjarsari District, Surakarta, Indonesia. Specifically, the study sought to analyze the associations of chrononutrition, emotional eating, and self-control with blood pressure in this population. This cross-sectional study evaluated how these three factors relate to blood pressure among hypertensive patients attending six community health centres (Puskesmas) in Banjarsari District, Surakarta, Indonesia. Using proportional random sampling, 115 participants were enrolled. Chrononutrition, emotional eating, and self-control were assessed using the Chrononutrition Questionnaire, the Emotional Eater Questionnaire, and a modified Brief Self-Control Scale, respectively. All three instruments had been tested and demonstrated good to excellent validity and reliability, with Cronbach’s alpha values ranging from 0.867 to 0.928. Blood pressure was measured using a validated digital sphygmomanometer following the 2025 American Heart Association standards. Ordinal logistic regression adjusted for age and sex showed that poor chrononutrition (AOR = 4.424), emotional eating (AOR up to 15.503), and low self-control (AOR = 20.752) were each independently associated with higher blood pressure categories, with self-control being the strongest predictor. These findings suggest that integrating behavioural assessments into primary hypertension care is warranted.