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Differences In Counting The Number of Leukocytes Using Cermai Fruit (Phyllantus acidus) Juice and Turk Solution Using The Counting Room Method Akhmad Rizal Effendi; Gilang Nugraha; Andreas Putro Ragil Santoso
Jurnal Analis Medika Biosains (JAMBS) Vol 10, No 2 (2023): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v10i2.324

Abstract

Leukocytes play a role in the body's defense system. Counting the number of leukocytes can be done manually using turk solution. Glacial acetic acid in turk solution functions to lyse erythrocytes but this compound is included in compounds that are carcinogenic. There is a natural ingredient that can lyse blood cells other than leukocytes, namely Cermai fruit. Cermai fruit contains a weak acid, namely citric acid of 39,8% so that it can lyse blood cells other than leukocytes. This study aims to analyze the difference in the number of leukocytes in cermai fruit juice and turk solution. This type of research is experimental with simple random sampling technique. The sample of this research is cermai fruit which will be used to count the number of leukocytes in 10 respondents. The mean number of leukocytes in the control solution was 6.610 cells/mm3, 10% concentration 4.296 cells/mm3, 20% concentration 4.227 cells/mm3, 30% concentration 5.918 cells/mm3 and 100% concentration 5.745 cells/mm3. Data were analyzed using the Kruskal Wallis test and the sig. 0.001 <0,05 so H1 is accepted, which means there is a significant difference, so it is continued with the Post Hoc test. Post hoc test showed that there was no significant difference in the results of leukocyte counts using cermai fruit with concentrations of 30% and 100% compared to the control (p>0,05). Meaning that only the concentrations of 30% and 100% showed the suitability of the number of leukocytes with the control so that these concentrations could be used as an alternative to 3% glacial acetic acid in turksolution.
Upaya Pencegahan Intoksikasi Merkuri Melalui Penyuluhan Pemanfaatan Herbal Bagi Masyarakat Kawasan Industri Sidoarjo Devyana Dyah Wulandari; Andreas Putro Ragil Santoso; Hotimah Masdan Salim; Endah Budi Permana Putri
Amaliah: Jurnal Pengabdian Kepada Masyarakat Vol 7 No 2 (2023): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPI UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v7i2.2370

Abstract

Merkuri merupakan salah satu logam yang berbahaya dan dapat menyebabkan efek toksik pada manusia. Paparan merkuri dapat ditimbulkan akibat kegiatan yang dapat menghasilkan merkuri, seperti pembakaran batu bara perumahan, proses industri, insinerator limbah, penambangan merkuri, emas, dan logam lainnya, serta penggunaan kosmetik yang mengandung merkuri. Persenyawaan merkuri beracun bagi sistem saraf pusat dan perifer. Efek berbahaya akibat paparan merkuri terjadi pada sistem saraf, pencernaan dan kekebalan tubuh, paru-paru dan ginjal, dan dapat berakibat fatal. Garam merkuri anorganik bersifat korosif pada kulit, mata, dan saluran pencernaan, dan dapat menyebabkan toksisitas ginjal jika tertelan. Tujuan dari kegiatan pengabdian ini dilakukan untuk mengedukasi masyarakat yang tinggal di wilayah industri tentang bahaya intoksikasi merkuri serta pemanfaatan herbal untuk mengurangi bahaya paparan merkuri. Metode pelaksanaan kegiatan adalah penyuluhan. Evaluasi kegiatan dilakukan dengan memberikan kuisioner untuk mengukur peningkatan pemahaman mitra. Hasil kegiatan ini adalah peningkatan pemahaman masyarakat tentang bahaya intoksikasi merkuri serta peningkatan keterampilan masyarakat dalam memanfaatkan herbal untuk mengurangi efek toksik merkuri. Berdasarkan nilai signifikansi P = 0,01 (P < 0,05) menunjukkan bahwa terdapat perbedaan signifikan pemahaman masyarakat sebelum dan sesudah mengikuti kegiatan pengabdian ini. Kegiatan ini dapat meningkatkan pemahaman masyarakat mitra tentang intoksikasi merkuri dan meningkatan keterampilan masyarakat dalam memanfaatkan herbal untuk mengurangi efek toksik merkuri.
MENGGAPAI ELIMINASI HEPATITIS VIRUS TAHUN 2030 DENGAN EDUKASI DI BEBERAPA KOTA JAWA TIMUR Ardyarini Dyah Savitri; Diaz Syafrie Abdillah; Andreas Putro Ragil Santoso; Nur Masruroh
SWARNA: Jurnal Pengabdian Kepada Masyarakat Vol. 1 No. 4 (2022): SWARNA: Jurnal Pengabdian Kepada Masyarakat, Desember 2022
Publisher : LPPM Sekolah Tinggi Ilmu Ekonomi 45 Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/swarna.v1i4.181

Abstract

Bertepatan dengan hari hepatitis pada 28 Juli, WHO mengingatkan akan target eliminasi hepatitis virus di dunia tahun 2030. Adanya serangan Covid-19 mengakibatkan program eliminasi berjalan lebih lambat dan tidak sesuai rencana. Pada World Hepatitis Day, WHO membawa tema “Bringing hepatitis care closer to you” dengan harapan dapat menggugah kewaspadaan masyarakat terhadap hepatitis. Di sisi lain, masih rendahnya pengetahuan masyarakat awam tentang hepatitis, maka, dirasa perlu adanya edukasi mengenai hepatitis virus yang sering terjadi di Indonesia (Hepatitis A, B dan C). Edukasi diberikan dengan metode seminar offline yang dilakukan di UINSA Surabaya, dan secara online untuk masyarakat Driyorejo, Gresik. Kegiatan seminar offline dihadiri oleh 50 orang, dan seminar online oleh 40 orang. Peserta berasal dari berbagai kalangan profesi. Tingkat pemahaman peserta dinilai dari aktivitas peserta dalam mengajukan pertanyaan serta penilaian kuesioner. Selama kegiatan offline tercatat lebih dari 5 peserta aktif bertanya, sedangkan pada kegiatan online ada 2 peserta yang mengajukan pertanyaan. Hasil kuesioner menunjukkan 81 (90%) peserta berpendapat materi mudah dipahami, 81 (90%) peserta menilai diskusi meningkatkan pemahaman, dan seluruh peserta (100%) menilai pemateri menguasai topik, serta seluruh peserta (100%) menganggap seminar bermanfaat. Kegiatan seminar ini cukup bermanfaat bagi masyarakat untuk dapat mengetahui gejala awal, cara penularan hepatitis serta penanganannya.
Deteksi Mikro Albumin Urine Sebagai Upaya Deteksi Untuk Pencegahan Diabetic Neuropati Pada Warga Desa Simo Angin-Angin Andreas Putro Ragil Santoso; Devyana Dyah Wulandari; Ardyarini Dyah Savitri; Dwi Handayani; S. P. Edijanto Penulis; Janetra Yudhis Nata P; Syinta Nur Isnaini; Nur Zalsabila Isnaini
PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT Vol. 3 No. 1 (2023): Prosiding Seminar Nasional Pengabdian Kepada Masyarakat : MEMAKSIMALKAN POTENSI
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/snpm.v3i1.1278

Abstract

Salah satu komplikasi diabetes adalah terjadinya kerusakan ginjal atau disebut nefropati diabetik, yang dapat menyebabkan gagal ginjal terminal sehingga penderita perlu menjalani cuci darah (hemodialisa) atau cangkok ginjal. Masih rendahnya pengetahuan masyarakat tentang pengetahuan tentang pemeriksaan urine serta Kurangnya kesadaran pentingnya tes awal pemeriksaan diabetes. Kegiatan pengabdian kepada masyarakat dilakukan dilakukan di Desa Simo Angin-Angin, Krian, Sidoarjo pada tahun 2023 yang dihadiri oleh 72 peserta. Metode pengabdian yang dilakukan yaitu dengan pendekatan melalui sosialisasi untuk pemahaman penyakit ginjal akibat diabet, manfaat pemahaman dilakukan dengan sosialisasi dilakukan pendekatan kembali terkait tingkat pemahaman, selanjutnya dilakukan pemeriksaan urine dilakukan sebagai bahan evaluasi pada masyarakat untuk mengetahui microalbumin urine pada responden. Berdasarkan kesimpulan masyarakat didapatkan tingkat pemahaman pemeriksaan urine dengan peningkatan sebesar 40%, dan berdasarkan hasil pemeriksaan albumin urine menunjukkan bahwa terdapat 37% yang menunjukkan hasil positif dan 63% merupakan hasil negatif. Hal tersebut menunjukkan pentingnya pemeriksaan urine untuk deteksi dini.
Leukosit Urine Sebagai Upaya Pencegahan Penyakit Pada Warga Desa Simo Angin-Angin S. P. Edijanto Penulis; Andreas Putro Ragil Santoso; Devyana Dyah Wulandari; Gilang Nugraha; Dwi Handayani; Janetra Yudhis Nata P; Syinta Nur Isnaini; Nur Zalsabila Isnaini
PROSIDING SEMINAR NASIONAL PENGABDIAN KEPADA MASYARAKAT Vol. 3 No. 1 (2023): Prosiding Seminar Nasional Pengabdian Kepada Masyarakat : MEMAKSIMALKAN POTENSI
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/snpm.v3i1.1297

Abstract

Leukosit dalam urin yang tinggi saat pengecekan medis bisa jadi penanda infeksi pada saluran kemih. Tingginya leukosit tersebut menandakan tubuh sedang melawan infeksi yang terjadi. Selain infeksi, penyumbatan atau obstruksi di saluran kemih juga bisa menjadi biangnya sehingga harus ditangani oleh dokter. Masih rendahnya pengetahuan masyarakat tentang pengetahuan tentang pemeriksaan urine serta kurangnya kesadaran pentingnya tes awal pemeriksaan. Kegiatan pengabdian kepada masyarakat dilakukan dilakukan di Desa Simo Angin-Angin, Krian, Sidoarjo pada tahun 2023 yang dihadiri oleh 72 peserta. Metode pengabdian yang dilakukan yaitu dengan pendekatan melalui sosialisasi untuk pemahaman penyakit ginjal akibat diabet, manfaat pemahaman dilakukan dengan sosialisasi dilakukan pendekatan kembali terkait tingkat pemahaman, selanjutnya dilakukan pemeriksaan urine dilakukan sebagai bahan evaluasi pada masyarakat untuk mengetahui leukosit urine pada responden Berdasarkan hasil sosialisai pada 72 masyarakat didapatkan tingkat pemahaman pemeriksaan urine dengan peningkatan sebesar 50%, dan berdasarkan hasil pemeriksaan leukosit urine menunjukkan bahwa terdapat 58,43% yang menunjukkan hasil positif dan 41,57% dengan hasil negatif. Hal tersebut menunjukkan pentingnya pemeriksaan urine untuk deteksi dini untuk kesehatan ginjal
Relationship between Blood Pressure and Urine Protein in Preeclampsia at Prima Husada Hospital Sidoarjo : Hubungan Tekanan Darah Dengan Protein Urine Pada Kejadian Preeklamsia Di RSU Prima Husada Sidoarjo Santoso, Andreas Putro Ragil; Masruroh, Nur; Amalia, Ikke Nanda; Santy, Wesiana Heris
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 3 No. 2 (2020): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v3i2.1081

Abstract

The problems related to pregnancy and childbirth including maternal and infant mortality rates can’t be removed from another causative factors that arise, one of the second cause from maternal mortality rates is preeclampsia, which is a specific disorder of hypertension caused by pregnancy at gestational age of more than 20 weeks with proteinuria and rarely occurs before 20 weeks gestational except if any kidney or trophoblastic disease. Hypertension and proteinuria to be a symptoms that often appears in preeclampsia diagnose. The relationship between of risk factor occur preeclampsia, that is blood pressure and protein urine which is the important indicator for enforcement of preeclampsia. The purpose of researchis analyze the relationship between of blood pressure and protein urine levels on the incidence of preeclampsia. The type of this research is analytic observational. Sample of this research is pregnant mother with preeclampsia in RSU Prima Husada Sidoarjo. The results use the Correlation Pearson test showed that p value for the systolic blood pressure is 0.791 and the diastolic blood pressure is 0.268, this is shows that blood pressure isn’t related with protein urine.
The Effect Of Using Personal Protection Equipment (PPE), Mileage, And Smoking Habits On Hair Lead (Pb) Levels: Pengaruh Penggunaan Alat Pelindung Diri (APD), Jarak Tempuh Dan Kebiasaan Merokok Terhadap Kadar Timbal (Pb) Rambut Wulandari, Devyana Dyah; Rohmah, Wardah; Nidianti, Ersalina; Santoso, Andreas Putro Ragil; Andini, Ary
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.1435

Abstract

Street sweepers, traffic officers, roadside sellers and motorcyclists, including students are subjects who are vulnerable to exposure to vehicle fumes. One of the air pollution generated from motor vehicle fumes is lead (Pb) which is toxic to humans and is accumulative. This study aimed to analyze the relationship between characteristic factors and lead levels in hair using the Atomic Absorption Spectroscopy (AAS) method. Respondents in this study were 32 male university students. The results showed a significance value of 0.274 (p> 0.05) on the parameter of PPE use, 0.049 (p <0.05) on the mileage parameter, and 0.576 (p> 0.05) on the smoking habit parameter. So it can be concluded that there is no effect of the use of PPE and smoking habits on hair lead levels and there is an effect of mileage on hair lead levels in student respondents.
Hubungan Paparan Pestisida Kadar Enzim Kolinesterase dengan Kadar Trigliserida pada Pekerja yang Terpapar Pestisida Golongan Organofosfat: Relationship of Pesticide Exposure to Cholinesterase Enzyme Levels with Triglyceride Levels in Workers Exposed to Organophosphate Group Pesticides Santoso, Andreas Putro Ragil; Wulandari, Devyana Dyah
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 2 No. 2 (2019): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i2.2992

Abstract

Alzaimer degerative diseases that attack the brain that occur due to several things including cholesterol and poisoning due to organopathic pesticides, cholinesterase. Triglycerides are a part of kolesterol which consists of about 20% of total cholesterol. Pesticide buildup in the body often occurs due to work risks. This study aims to determine how much cholinesterase activity and triglyceride levels are in workers exposed to organophosphate pesticides, and to determine the relationship of pesticide exposure to cholinesterase enzyme levels with triglyceride levels in workers who are exposed to workers exposed to pesticides. This research is an observational research with an experimental approach. The study was conducted at PT.X, which was exposed to 15 pesticides. This study uses a correlation test that will be shown if p <0.05. Based on the results of the study obtained based on the average results of cholinesterase activity obtained at 8,040 U/L while triglycerides at 186 mg/dL. And after the correlation test was obtained at 0.085 indicating that p> 0.05 so it was concluded that there was no relationship between cholinesterase activity with triglyceride levels.
Effects of Giving Alfamangios on Cholesterol Levels and Pancreatic Appearance in Diabetes Mellitus Induced Rats : Efek Pemberian Alfamangios Terhadap Kadar Kolesterol Dan Gambaran Pankreas Pada Tikus Terinduksi Diabetes Mellitus Kardina, Rizki Nurmalya; Santoso , Andreas Putro Ragil; Putri, Fildzah Karunia; Murtasiyah, Erna Dwi; Arif, Sheila Weni Astuti
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1618

Abstract

The isolate compound α-Mangostin was the most dominant compound found in the rind and trunk of the mangosteen fruit tree (Garcinia mangostana L.). These compounds are reported to have many pharmacological activities such as antibacterial, antifungal, antidiabetic, anti-cancer and several other bioactivities. The aim of this research was to measure the activity of α-Mangostin isolate using 13C and 1H NMR and to find out whether this compound had bioactivity on pancreatic physiology and histopathology in type II diabetes mellitus rats with the parameters measured were cholesterol and pancreatic histopathology. This research was conducted at the Laboratory of the Faculty of Veterinary Medicine, Airlangga University, Surabaya. This research is a true experimental type because the data were taken through laboratory tests with the treatment of the research sample. The sample in this study were rats with induced diabetes mellitus. 30 rats were separated into 5 groups for each group of 6 rats. The results of this study There are differences in the effect of giving alpha mangiostin on blood cholesterol levels in rats that have been induced by diabetes mellitus, and there is a change in the morphology of the pancreas caused by free radicals.
Relationship of Leukocyte Examination to Intra Uterine Growth Restriction (IUGR) in Pregnant Women Experiencing Anemia: Hubungan Pemeriksaan Leukosit Terhadap Intra Uterine Growth Restriction (IUGR) Pada Ibu Hamil Mengalami Anemia Santoso, Andreas Putro Ragil; Masruroh, Nur; Filia, Sisca
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 2 (2022): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i2.1687

Abstract

Anemia in pregnant women will often occur because of increasing gestational age, the increasing need for nutrients in the form of iron in the body which increases during the 2nd to 3rd trimester of pregnancy. Anemia has an impact of around 14-62% on pregnant women including the occurrence of Intra Uterine Growth Restriction (IUGR) which is a condition that causes fetal growth to be stunted which is characterized by the size and weight of the baby that is not appropriate during pregnancy. The next thing to worry about is the emergence of infection if the patient has IUGR. The purpose of this study was to analyze the relationship of leukocytes to IUGR in pregnant women who are anemic with the parameters measured being leukocyte levels, IUGR values in anemic patients. The study was carried out in an analytic observational manner, then samples were obtained from 24 patients. Then, the patients filled out informed consent indicating that the patient was willing to be a research sample. Furthermore, the patient's blood was taken to measure leukocyte levels and based on the KIA book, IUGR levels were measured. Based on the above, it shows that the value of the results of the Spearman correlation test is 0.085 (p> 0.05). It can be concluded that there is no relationship between leukocyte levels and IUGR values in anemic patients at IBI Surabaya Hospital.
Co-Authors , Wirda Nur Fa'ida Ahmad Miftahul Kaunain Aishella, Maulida Akhmad Rizal Effendi Alfian Daffa Alfri Danti Izky Oktavia Amalia, Ikke Nanda Andini, Ary Anggriyani, Rinda Anita Rizki Rahmawati Asror Ardyarini Dyah Savitri Ardyarini Dyah Savitri Ardyarini Dyah Savitri Arif, Sheila Weni Astuti Arifina, Rosyidatul Arvian Nur Amalina Devyana Dyah Wulandari Devyana Dyah Wulandari Devyani Diah Wulansari Devyani Dyah Wulansari Diaz Syafrie Abdillah Dra. Wieke Sri Wulan, S.T., MARS., M. Kes Dwi Handayani Effendi, Akhmad Rizal Ekawati, Evy Ratnasari Endah Budi Permana Putri Endah Budi Permana Putri Ersalina Nidianti Fadlillah Triasmoro Iskandar Filia, Sisca Gilang Nugraha Halimatul Afifah Hanum, Mufida Heris Santy, Wesiana Hotimah Masdan Salim Imratul Mukarramah Indaryanti, Reski Novita Janetra Yudhis Nata P Kamelia, Dina Kardina, Rizki Nurmalya Khoir, Intan Wahyunillah Zaidah Khusnah, Hidayatul Lili Susan Rahmawati Ma'at, Suprapto Mardhotillah, Rachma Rizqina Mega Silvia Anggraini Sukri Mella Rahmawati Mukminin Mufida, Nisaul Muhammad Afwan Romdloni Muhammad Taufiq Hidayat Muhammad Taufiq Hidayat Muhammad, Akbar Reza Mukhtar Adi Nugroho Murtasiyah, Erna Dwi Nathalya Dwi Kartika Sari Nesa Emilia Maretha Nila, Hartatiek Nur Izzatul Awaliyah Nur Masruroh Nur Masruroh Nur Masruroh Nur Masruroh, Nur Nur Zalsabila Isnaini Pradana, Muhammad Sungging Pratiwi, Viera Nuriza Prayekti, Endah Putri, Fildzah Karunia Rahayu, Mita Rahmawati, Lili Susan Retno Kawuri Rindi Anifa Laloda Rizki Nurmalya Kardina Robert Aditya Wijanarko Rohmah, Wardah S, Widya Novida S. P. Edijanto Penulis Salim, Hotimah Masdan Santoso, Setyo Dwi Setiarsih, Dini Soebagijo Poegoeh Edjianto Suhariyadi Sunaryo, Merry Suprapto Maat Syinta Nur Isnaini Ulan, Della Citra Uswatun Hasanah Widya Novitasari Wildani Thoyyibah Wiwi Azlina Syawalien Wulansari, Devyani Diah Wulansari, Devyani Diah Zazabilla, Indira