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Ekstrak Etanol Daun Binahong (Anredera cordifolia) di Berbagai Tingkat Konsentrasi terhadap Bakteri Staphylococcus aureus dan Pseudomonas aeruginosa Wiwi Azlina Syawalien; Andreas Putro Ragil Santoso
Detector: Jurnal Inovasi Riset Ilmu Kesehatan Vol. 3 No. 3 (2025): Agustus: Jurnal Inovasi Riset Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/detector.v2i3.4198

Abstract

Burns can cause infection, hinder healing, and increase the risk of long-term complications. Staphylococcus aureus and Pseudomonas aeruginosa often infect burn wounds in general, infections are treated with antibiotics, but continued use of antibiotics can cause bacterial resistance. Binahong leaves (Anredera cordifolia) have potential as a substitute for antibiotics because of their antibacterial properties from active compounds such as alkaloids, polyphenols, tannins, saponins and ascorbic acid. This research aims to activate the antibacterial ability of binahong leaf ethanol extract against S. aureus and P. aeruginosa. This research uses an experimental method with a control group design using diffusion and dilution methods at varying concentrations. Statistical analysis of the inhibition zone showed that there was a significance difference of <0.05 between treatment groups. In the solid diluted method, S. aureus obtained an MIC value of 10.5% and a MBC of 11.5%, whereas P. aeruginosa had an MIC of 14.5% and a MBC of 15%. The results showed that the ethanol extract of binahong leaves was more sensitive to S. aureus than P. aeruginosa.
Pelatihan Pembuatan Kit Deteksi Merkuri Sederhana Untuk Peningkatan Keterampilan Laboratorium bagi Pelajar SMK Muhammadiyah I Pandaan Wulandari, Devyana Dyah; Santoso, Andreas Putro Ragil; Salim, Hotimah Masdan; Putri, Endah Budi Permana; Nugroho, Mukhtar Adi
Indonesia Berdaya Vol 5, No 3 (2024)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.2024896

Abstract

Merkuri merupakan logam berat yang berbahaya bagi kesehatan manusia. Diketahui bahwa merkuri sebagian besar tertelan melalui konsumsi ikan-ikan laut, air yang tercemar, bahkan penggunaan kosmetik melalui kulit. Oleh karena itu pengabdian ini dilakukan bertujuan untuk memberikan wawasan tentang bahaya logam merkuri serta keterampilan mendeteksi merkuri menggunakan kit sederhana.  Pelaksanaan kegiatan ini dilakukan berupa seminar untuk memberikan wawasan tentang merkuri dan pelatihan pembuatan kit sederhana untuk mendeteksi merkuri. Hasil menunjukkan bahwa tingkat pemahaman peserta terhadap materi kegiatan pengabdian dengan jumlah peserta sebanyak 47 peserta terjadi peningkatan pemahaman terhadap pengetahuan tentang merkuri sebanyak 32%, terhadap pengetahuan tentang bahaya merkuri sebesar 32%, terhadap pemahaman tentang kit deteksi merkuri meningkat sebesar 38%, pemahaman keterampilan membuat kit deteksi merkuri meningkat sebanyak 38%, dan pemahaman keterampilan cara deteksi merkuri menggunakan kit sederhana meningkat sebanyak 57%.Dapat disimpulkan bahwa kegiatan ini memberikan manfaat bagi peserta pengabdian yaitu siswa/i SMK Muhammadiyah I Pandaan.
Tindakan Preventif Penyakit Degeneratif dengan Pemeriksaan Kesehatan di Desa Banjaran Gresik Wulandari, Devyana Dyah; Ragil Santoso, Andreas Putro; Pratiwi, Viera Nu'riza; Wulansari, Devyani Diah; Aishella, Maulida; Ma'at, Suprapto
Indonesian Journal of Community Services Vol 7, No 2 (2025): November 2025
Publisher : LPPM Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/ijocs.7.2.204-211

Abstract

Gaya hidup, pola makan, stres, dan aktivitas fisik seperti olahraga sangat berdampak pada masalah kesehatan Indonesia saat ini. Prevalensi penyakit degeneratif meningkat sebagai akibat dari perubahan gaya hidup. Penyakit degeneratif meliputi hipertensi, diabetes melitus, stroke, dan gagal ginjal kronis semakin banyak dijumpai di Indonesia setiap tahunnya. Program pengabdian ini dilakukan bertujuan untuk melakukan pemeriksaan kesehatan sebagai tindakan preventif penyakit degeneratif bagi masyarakat Desa Banjaran, Gresik. Pemeriksaan kesehatan yang dilakukan antara lain pemeriksaan tekanan darah, kadar glukosa darah, kadar kolesterol total, dan kadar asam urat. Pemeriksaan kesehatan dilakukan di Balai Desa Banjaran, Gresik dan diikuti sebanyak 23 responden. Pemeriksaan dilakukan menggunakan tensimeter untuk mengukur tekanan darah, sedangkan untuk kadar glukosa darah, kadar kolesterol total, dan kadar asam urat dilakukan menggunakan alat Point of Care Test (POCT) merk Accucheck. Dari hasil pemeriksaan tekanan darah, 44% responden memiliki tekanan darah normal, 17% pre-hipertensi, dan 39% hipertensi. Hasil pemeriksaan glukosa darah sewaktu diketahui 4% responden dengan kadar glukosa darah tinggi, sedangkan 96% responden memiliki kadar glukosa darah normal. Data hasil pemeriksaan kesehatan kadar kolesterol total sebanyak 48% responden memiliki kadar kolesterol total normal sedangkan 52% responden memiliki kadar kolesterol total tinggi. Hasil pemeriksaan kadar asam urat diketahui sebesar 74% responden memiliki kadar asam urat normal dan 26% responden memiliki kadar asam urat tinggi. Hasil pemeriksaan digunakan sebagai bahan konsultasi sebagai bentuk edukasi pentingnya melakukan pemeriksaan kesehatan. Dari hasil edukasi diketahui tingkat pemahaman masyarakat meningkat sebesar 52,17%. Dapat disimpulkan bahwa kegiatan pengabdian ini memberikan dampak positif bagi kesehatan masyarakat Desa Banjaran, Gresik. Lifestyle, diet, stress, and physical activity such as exercise have a significant impact on Indonesia's current health problems. The prevalence of degenerative diseases is increasing as a result of lifestyle changes, especially in big cities. Degenerative diseases including hypertension, diabetes mellitus, stroke, and chronic kidney failure are increasingly found in Indonesia every year. This community service program aims to conduct health checks as a preventive measure for degenerative diseases for the people of Banjaran Village, Gresik. The health checks carried out include blood pressure, blood glucose levels, total cholesterol levels, and uric acid levels. Health checks are carried out using a tensiometer to measure blood pressure, while for blood glucose levels, total cholesterol levels, and uric acid levels, they are carried out using the Accucheck brand Point of Care Test (POCT) tool. The results of the examination are used as consultation material as a form of education on the importance of conducting health checks. From the results of the education, it is known that the level of public understanding has increased by 52.17%. This proves that this community service activity has a positive impact on the health of the people of Banjaran Village, Gresik.
Analysis of Anemia Incidence Determinants among Female Students at Islamic Boarding School Al Hidayah 2 Bangkalan Dini Setiarsih; Rizki Nurmalya Kardina; Andreas Putro Ragil Santoso; Ahmad Miftahul Kaunain; Halimatul Afifah
Journal of Ners and Midwifery Vol 9 No 2 (2022)
Publisher : STIKes Patria Husada Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26699/jnk.v9i2.ART.p148-153

Abstract

The incidence of anemia is common in adolescent girls. Anemia causes decreased learning achievement due to lack of concentration. This research aimed to analyze the determinant factors associated with the incidence of anemia in female students at Islamic Boarding School Al Hidayah 2 Bangkalan. The research was observational analytic, a cross sectional design. The population was female students at Islamic Boarding School Al Hidayah 2 and the sample size was 72 people. The independent variables include menstrual patterns, sleep patterns, consumption patterns of food sources of iron and nutritional status. The dependent variable was anemia status. Data collection on menstrual patterns and sleep patterns used a questionnaire, consumption patterns with the Food Frequency Questionnaire and anemia status by testing hemoglobin levels. Analysis of the data by Contingency Coefficient test. The results showed that 27.8% of subjects experienced menorrhagia, 54.2% had poor sleep patterns, 58.3% had good food consumption patterns, 25.0% had underweight nutritional status, and 13.9% subjects experienced anemia. Correlation tests showed that the menstrual pattern was significantly related to anemia status (p=0.048). Sleep pattern (p=0.776), food consumption pattern (p=0.908) and nutritional status (p=0.462) were not significantly correlated with the incidence of anemia. Menstrual pattern is the most influential factor of anemia incidence.  The longer of menstrual period will cause the greater the chance of the subject experiencing anemia. 
Improving Public and Environmental Health Through Clean and Healthy Living Behavior Education and Bacterial Examination Prayekti, Endah; Santoso, Andreas Putro Ragil; Sunaryo, Merry; Indaryanti, Reski Novita; Rahmawati, Lili Susan; Kamelia, Dina
Indonesia Berdaya Vol 7, No 1 (2026)
Publisher : UKInstitute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47679/ib.20261400

Abstract

A major problem frequently faced by the public is clean and healthy living behaviors (PHBS). According to the Indonesian Ministry of Health in 2014, health can be achieved by changing unhealthy behaviors into healthy ones and creating a health-supportive environment. Effective measures include handwashing with soap and environmental inspections. This activity aims to increase public awareness of the importance of clean and healthy living behavior (PHBS), while also introducing the dangers of microbiological contamination that can occur on hands and water. Community service activities are carried out through the stages of pre-test, education, post-test, sampling, and sample examination. Of the 34 respondents, the majority experienced a significant reduction in hand bacteria, with 21 showing a reduction in hand bacteria of more than 70% and some reaching 99–100%. Well water examinations at several public facilities for Pekingan village residents showed the presence of Coliform bacteria exceeding the safe limits according to the Ministry of Health Regulation, indicating that the water is not suitable for direct consumption due to possible contamination by domestic waste, septic tank seepage, or poor environmental sanitation. The conclusion of this Community Service activity is that there is an increase in respondents' understanding and an increase in their ability to practice proper handwashing. Water sanitation in public facilities needs to be considered and improved because it should not be used for consumption.
THE EFFECT OF BEETROOT (Beta vulgaris L.) JUICE ON CHOLINESTERASE ACTIVITY IN FARMERS EXPOSED TO ORGANOPHOSPHATE PESTICIDES Wulandari, Devyana Dyah; Santoso, Andreas Putro Ragil; Wulansari, Devyani Diah
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 1 No 2 (2019): Laboratory Analysis Applied to Medical Properties
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v1i2.1215

Abstract

A decrease in cholinesterase (chE) enzyme activity is an indicator of pesticide poisoning, especially organophosphate pesticides. The chE activity reduction will result in an increase in the amount of acetylcholine and will bound to muscarinic and nicotinic receptors in the central and peripheral nervous system which can lead to the onset of Alzheimer's disease. However, antioxidant products can slow the progression of Alzheimer's disease by protecting neurons from oxidative stress. Red Beetroot (Beta vulgaris L.) contains betalains and phenolic compounds which act as an antioxidants that are capable of preventing such illness. This study aims to prove the concept that antioxidant compounds in red beetroot juice can increase the chE activity in subjects exposed to organophosphate pesticides. This research is an observational study with an experimental approach. This research used 25 farmers who were exposed to organophosphate pesticides as respondents. They were given 500 ml of beetroot juice twice a day for 2 consecutive months. Cholinesterase levels were measured before and after consuming red beet juice. Measurement of cholinesterase levels was carried out using a kinetic photometric test. This method was developed based on recommendations from the German Society of Clinical Chemistry (DGKC). The results showed that the average of chE (U/L) Level Before Treatment was 8.102 and 8.380 after treatment with a p value 0,62. It can be concluded that there was an increase in the level of cholinesterase but it was not statistically significant. This may be caused by a different response to activity of cholinesterase after consuming beetroot juice in each subjects, age difference, smoking habits, and personal protective equipment.
ASSOCIATION BETWEEN TRIGLYCERIDE SERUM LEVELS AND GLOMERULAR FILTRATION RATE (eGFR) IN PATIENTS WITH CHRONIC RENAL FAILURE AT JEMURSARI ISLAMIC HOSPITAL SURABAYA, INDONESIA Hasanah, Uswatun; Suhariyadi; Putro Ragil Santoso, Andreas
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 2 No 2 (2020): Increasing Research in Diagnostic Laboratory Testing
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v2i2.1668

Abstract

Chronic Renal Failure (CRF) is a progressive and irreversible decrease in kidney function. One risk factor that affects the progression of CRF is dyslipidemia due to abnormalities of lipid metabolisms. Dyslipidemia is characterized by the increase level of total cholesterol, LDL cholesterol, triglycerides, and a decrease in HDL cholesterol level. eGFR is a parameter for assessing the excretion function, by calculating the amount of filtrate produced by the renal glomerulus. This study aims to determine the relationship between serum triglyceride levels with eGFR in patient suffering from CRF at Jemursari Islamic Hospital Surabaya. This type of research is descriptive experimental with cross–sectional design. The study population was the patients with CRF. The primary data in this study was the results of examination of serum triglyceride levels in patients with CRF. The secondary data (serum creatinine levels, body weight, age, and sex) was obtained from medical records of CRF patients in February 2019. As much as 12% of patients were in the 40–50 years old category, 36% of patients were 51–60 years old, 44% of patients were 61–70 years old, and 8% of patients were 71–80 years old. 72% of patients were male. The mean triglyceride level was 146.68 mg/dL and the average eGFR was 19.86 mL/min/1.73m2. The relationships between triglyceride levels and eGFR was carried out by the Spearman–rho test where r value was –0.442 and value was 0.027. It was concluded that there was a significant negative correlation between serum triglyceride levels and eGFR in patients with CRF.
PELATIHAN PRAKTIS POCT: DETEKSI DINI HB DAN GLUKOSA DARAH UNTUK REMAJA SEHAT Soebagijo Poegoeh Edjianto; Ary Andini; Andreas Putro Ragil Santoso; Gilang Nugraha; Anita Rizki Rahmawati Asror; Robert Aditya Wijanarko
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 6 (2024): Vol. 5 No. 6 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i6.42626

Abstract

Di Indonesia, kasus anemia dan diabetes melitus masih mendapat perhatian tinggi terutama kesehatan bagi remaja. Anemia berkaitan erat dengan kadar Hb dalam darah, sementara diabetes melitus berkaitan dengan kadar glukosa darah. Salah satu pemeriksaan sederhana yang dapat dilakukan adalah dengan metode Point of Care Testing (POCT), yang dapat dilaksanakan di luar laboratorium, menggunakan peralatan portabel yang dekat dengan pasien untuk mendapatkan hasil secara cepat dan mengidentifikasi kadar hemoglobin (Hb) serta glukosa. Salah satu upaya untuk memberikan edukasi tentang penggunaan POCT bagi remaja khususnya dilakukan di SMK Muhammadiyah 1 Pandaan, dengan tujuan meningkatkan pengetahuan remaja mengenai pentingnya pemeriksaan kesehatan dan cara menggunakan alat POCT untuk pencegahan penyakit. Kegiatan pengabdian masyarakat dilaksanakan pada Rabu, 24 Juli 2024, di Aula SMK Mutu Pandaan, diikuti oleh 47 siswa dari jurusan Teknik Laboratorium Medik, Asisten Keperawatan, dan Farmasi Klinis dan Komunitas. Kegiatan ini terdiri dari dua tahap: penyuluhan dan pelatihan/praktek penggunaan POCT secara langsung. Hasil evaluasi menunjukkan bahwa tingkat pemahaman siswa terkait pemeriksaan Hemoglobin (Hb) dan Glukosa menggunakan POCT mencapai rata-rata 85,10, menandakan keberhasilan penyuluhan. Pelatihan diikuti oleh tujuh peserta, di mana dukungan dari dosen dan mahasiswa Analis Kesehatan mendapat penilaian sangat membantu (71,4%) dan tingkat kepuasan peserta mencapai 100%.
Co-Authors , Wirda Nur Fa'ida Ahmad Miftahul Kaunain Aishella, Maulida Akhmad Rizal Effendi Alfian Daffa Alfri Danti Izky Oktavia Amalia, Ikke Nanda Andini, Ary Anggriyani, Rinda Anita Rizki Rahmawati Asror Ardyarini Dyah Savitri Ardyarini Dyah Savitri Ardyarini Dyah Savitri Arif, Sheila Weni Astuti Arifina, Rosyidatul Arvian Nur Amalina Devyana Dyah Wulandari Devyana Dyah Wulandari Devyani Diah Wulansari Devyani Dyah Wulansari Diaz Syafrie Abdillah Dra. Wieke Sri Wulan, S.T., MARS., M. Kes Dwi Handayani Effendi, Akhmad Rizal Ekawati, Evy Ratnasari Endah Budi Permana Putri Endah Budi Permana Putri Ersalina Nidianti Fadlillah Triasmoro Iskandar Filia, Sisca Gilang Nugraha Halimatul Afifah Hanum, Mufida Heris Santy, Wesiana Hotimah Masdan Salim Imratul Mukarramah Indaryanti, Reski Novita Janetra Yudhis Nata P Kamelia, Dina Kardina, Rizki Nurmalya Khoir, Intan Wahyunillah Zaidah Khusnah, Hidayatul Lili Susan Rahmawati Ma'at, Suprapto Mardhotillah, Rachma Rizqina Mega Silvia Anggraini Sukri Mella Rahmawati Mukminin Mufida, Nisaul Muhammad Afwan Romdloni Muhammad Taufiq Hidayat Muhammad Taufiq Hidayat Muhammad, Akbar Reza Mukhtar Adi Nugroho Murtasiyah, Erna Dwi Nathalya Dwi Kartika Sari Nesa Emilia Maretha Nila, Hartatiek Nur Izzatul Awaliyah Nur Masruroh Nur Masruroh Nur Masruroh Nur Masruroh, Nur Nur Zalsabila Isnaini Pradana, Muhammad Sungging Pratiwi, Viera Nuriza Prayekti, Endah Putri, Fildzah Karunia Rahayu, Mita Rahmawati, Lili Susan Retno Kawuri Rindi Anifa Laloda Rizki Nurmalya Kardina Robert Aditya Wijanarko Rohmah, Wardah S, Widya Novida S. P. Edijanto Penulis Salim, Hotimah Masdan Santoso, Setyo Dwi Setiarsih, Dini Soebagijo Poegoeh Edjianto Suhariyadi Sunaryo, Merry Suprapto Maat Syinta Nur Isnaini Ulan, Della Citra Uswatun Hasanah Widya Novitasari Wildani Thoyyibah Wiwi Azlina Syawalien Wulansari, Devyani Diah Wulansari, Devyani Diah Zazabilla, Indira