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OPTIMASI IDENTIFIKASI BORAKS MENGGUNAKAN PEREAKSI DIETILDITIOKARBAMAT SECARA SPEKTROFOTOMETRI UV-Vis Armon Fernando
Jurnal Penelitian Farmasi Indonesia Vol. 4 No. 2 (2015): jpfi
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

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Abstract

Identification of optimization studies have been conducted borax in grilled meatballs with diethyldithiocarbamate reagent (DEDTC) and detected byUV-Vis spectrophotometer. Samples containing borax in the furnace at a temperature of 600 ⁰C for ± 3 hours and treated with a solution of 10%diethyldithiocarbamate in NaOH 0.2 N. The results derivatization diethyldithiocarbamate borax with 2 ml of 10% at a temperature of 40 ⁰C or 60 minto detect a wavelength of 422 nm. Boron-diethyldithiocarbamate complex produced more stable in methanol and yellow
Uji Aktivitas Tabir Surya Ekstrak Etanol Daging Buah Jambu Biji Merah dan Jambu Biji Putih (Psidium guajava L.) Mustika Furi; Armon Fernando; Musyirna Rahmah Nasution
Jurnal Penelitian Farmasi Indonesia Vol. 7 No. 2: JPFI
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Farmasi Jl. Kamboja Simpang Baru-Panam, Pekanbaru, Riau 28293 Telp. (0761) 588006, Fax. (0761) 588007 e-mail: editor-jpfi@stifar-riau.ac.id

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Abstract

Guava fruit (Psidium guajava. L.) is consist at phenolics content that have antioxidant activirt and the possibility of using as sunscreen. The purpose of this research was to determine the concentration of extracts that have a potential sunscreen profile by determining the value of erythema transmission, pigmentation transmission and sun protection factor (SPF). Sunscreen activity was carried out in vitro using UV-Vis Spectrophotometer. Ethanol extract, red guava and white guava fruit are made to concentration of 100; 150; 200; 250 ppm, each absorption was measured in the UV A and UV B areas. As result the extract of red guava at a concentration of 250 ppm had %Te value was 15.32% which was included in the category fast tanning, %Tp was 25.4% which was included in the sunblock category and the SPF value was 8,228 which was categorized as maximum protection. The extract of white guava at a concentration of 250 ppm had %Te value of 12.51% which was included in Suntan standard category, the % Tp value was 21.97% which belongs to the sunblock category and the SPF value was 8, 945 which was categorized as maximum protection. Keyword : Guava fruit, SPF, %Te, %Tp
Formulasi Losion Antioksidan Ekstrak Buah Stroberi (Fragaria Ananassa) Deni Anggraini; Armon Fernando; Nurul Elisa
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 14 No. 02 Desember 2017
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (403.804 KB) | DOI: 10.30595/pharmacy.v14i2.1831

Abstract

Penelitian tentang formulasi losion antioksidan dari ekstrak buah stroberi (Fragaria ananassa) dengan konsentrasi 0,5; 1; dan 2% telah dilakukan. Aktivitas antioksidan losion ditentukan dengan menghitung nilai IC50. Aktivitas antioksidan losion pada konsentrasi 0,5; 1; dan 2% dinilai sebagai antioksidan yang sangat kuat, dengan nilai IC50 berturut-turut 0,47 ppm; 0,82 ppm; dan 1,53 ppm. Evaluasi formula losion antioksidan meliputi organoleptis, homogenitas, stabilitas, dan pH. Hasil penelitian menunjukkan bahwa sediaan losion tidak berubah dan stabil selama 8 minggu penyimpanan.
Uji Aktivitas Antioksidan Dari Ekstrak Bekatul Padi Ketan Merah Dan Hitam (Oryza Sativa L. Var. Glutinosa) Dan Formulasinya Dalam Sediaan Krim Wira Noviana Suhery; Armon Fernando; Netralis Has
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 13 No. 01 Juli 2016
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

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Abstract

ABSTRAK Bekatul merupakan hasil samping proses penggilingan padi yang mengandung senyawa bioaktif seperti tokoferol, tokotrienol, dan oryzanol. Penelitian ini bertujuan untuk menguji aktivitas antioksidan dari ekstrak bekatul padi ketan (Oryza sativa L. var. glutinosa) merah dan hitam kemudian memformulasikannya dalam bentuk sediaan krim. Pengujian aktivitas antioksidan dilakukan dengan metode DPPH (2,2-difenil-1-pikrihidrazil). Hasil uji aktivitas antioksidan dari ekstrak bekatul padi ketan merah dan hitam, diperoleh nilai IC50 berturut-turut sebesar 31,7525 dan 434,7525 ppm. Selanjutnya ekstrak bekatul padi ketan merah dan hitam diformulasikan dalam bentuk sediaan krim tipe M/A dengan konsentrasi ekstrak bekatul padi ketan merah (FI) dan hitam (FII) masing-masing 2,5%. Hasil evaluasi fisik sediaan krim yang meliputi organoleptis, homogenitas, pH, stabilitas terhadap perubahan suhu, uji daya menyebar, uji daya tercuci dan uji iritasi menunjukkan bahwa sediaan krim ekstrak bekatul padi ketan merah (FI) dan hitam (FII) memenuhi persyaratan dan tidak mengiritasi selama 8 minggu penyimpanan. Hasil uji aktivitas antioksidan sediaan krim menunjukkan persen inhibisi untuk FI dan FII masing-masing sebesar 95,0974 dan 92,3569% pada minggu pertama, dan 89,9576 dan 86,9537% pada minggu kedelapan. Kata kunci: ekstrak bekatul, padi ketan merah, padi ketan hitam, antioksidan, krim. ABSTRACT Rice bran is a by-product of rice milling process that contain bioactive compounds such as tocopherol, tocotrienol, and oryzanol. This study aimed to test the antioxidant activity of the extract of red and black glutinous rice bran (Oryza sativa L. var. glutinosa) and then formulatethem into cream. Testing of antioxidant activity using DPPH (2,2-diphenyl-1-pikrihidrazil). The IC50 of the extract of red and black glutinous rice bran are 31.7525 and 434.7525 ppm, respectively. Subsequently, extract of red and black glutinous rice bran is formulated into type o/w cream with concentration of 2.5%. The results of evaluation of physical cream consist of organoleptic, homogeneity, pH, stability to temperature changes, power test spread, test of power washed and test of irritation. The results showed that the cream of both red (FI) and black (FII) glutinous rice bran extract meet the physical properties requirements and do not irritate during the 8 weeks of storage. The result of antioxidant activity test showed that inhibition percentage of FI and FII are 95.0974 and 92.3569% in the first week, and 89.9576 and 86.9537% in the eighth week, respectively. Key words: extract of rice bran, glutinous rice bran red, glutinous rice bran black, antioxidant, cream.
Pengaruh Proses Pengeringan Terhadap Kadar Total Fenolik Dan Flavonoid Ekstrak Metanol Kubis Ungu(BrassicaoleraceaeL) Armon Fernando; Azkia Wanudya Rahmadhani; Emma Susanti
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 2 No 1 (2023): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v2i1.796

Abstract

Purplecabbage(BrassicaoleraceaeL.)isoneoftheagriculturalproductsinIndonesiawhoseexistenceisstartingtobequitewellknownbythepublic.Purple cabbage contains secondary metabolites that are thought to have antioxidant activity, the name is flavonoids and phenolics. This study aims toexamine the effect of the drying process of purple cabbage extract on total phenolic and flavonoid using 3 drying methods, wind drying, light bulb andoven.Thetestresultsshowedthatthemethanolextractofpurplecabbageonwinddryinghadthehighesttotalphenolicandflavonoidcontentobtainedin the methanol extract of the wind drying method, then the methanol extract of oven drying and drying using a light bulb. Of the 3 methods of dryingpurplecabbagemethanolextract,itdidnothavea significanteffect (p>0.05)on thetotalphenolicand flavonoidcontent.
PENGARUH WAKTU PERENDAMAN SEBELUM SONIKASI TERHADAP KADAR ASIATIKOSIDA PADA EKSTRAK DAUN PEGAGAN AIR (HYDROCOTYLE VULGARIS L.) SECARA KROMATOGRAFI CAIR KINERJA TINGGI (KCKT) Armon Fernando; Fadhilatun Khoiriyah
Ensiklopedia of Journal Vol 5, No 3 (2023): Volume 5 No. 3 Edisi 1 April 2023
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (52.744 KB) | DOI: 10.33559/eoj.v5i3.1669

Abstract

Pegagan air (Hydrocotyle vulgaris L.) is one of the plants used as medicine, one of the contents of pegagan air (Hydrocotyle vulgaris L.) is asiaticoida. Asiaticosides are known having antioxidant and neuroprotective activities. This research aims at finding out the effect of immersion time before sonication of pegagan air (Hydrocotyle vulgaris L.) toward the leaf extract on asiaticoside levels. Extractions parameters used are immersion time and sonication time. The asiaticoside level was analyzed using high performance liquid chromatography by column C-18, the mobile phase of methanol : water (70:30), flow rate of 1 ml/min and detected at wavelength 206 nm. Calibration curves were made by using a series of concentrations of 2-14 ppm with a regression equation y = 11656x + 142673. Optimum asiaticoside levels in pegagan air (Hydrocotyle vulgaris L.) leaf extract were obtained at the time of immersion for two hours with sonication time for 15 minutes. The asiaticoside level obtained in the extract of pegagan air (Hydrocotyle vulgaris L.) leaf was 0,1699 mg/10 mg extract with a percentage of 1.6842%.Keywords: Pegagan air, Asiaticoside, Immersion, Sonication, HPLC.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK DAN FRAKSI DARI AKAR DAN BATANG TUMBUHAN SEKUNYIT (Fibraurea tinctoria Lour) Rahayu Utami; Dwi Winarsih; Armon Fernando; Haiyul Fadhli; Mustika Furi; Emma Susanti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 12 No. 2 (2020): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (530.712 KB) | DOI: 10.35617/jfionline.v12i2.50

Abstract

Sekunyit (Fibraurea tinctoria Lour) is plant species that has been using widely as traditional medicine such as a cure for diarrhea. This study was conducted to determine the antibacterial activity of extract and fractions of its root and stem against bacteria that cause diarrhea. The sample of root and stem were macerated with ethanol and then followed by ultrasonication process for 30 minutes. Fractionation process was performed by acid-base method using three different solvents which were n-hexane, chloroform and n-butanol. The extract and fractions were tested for its antibacterial activity using agar diffusion method at tested concentrations of 30; 15; 7.5; 3.75 and 1.88%. The result showed that the ethanol extract, n-hexane, chloroform A and chloroform B fractions of the root and stem provided antibacterial activity against all tested bacteria with weak to medium activity. Whereas the n-butanol fraction did not give any activity, either to Escherichia coli, Salmonella typhi, Staphylococcus aureus as well as Vibrio cholerae.
Formulation and Antioxidant Activity Test of Rice Bran Extract Cream from Two Varieties of White Rice Wira Noviana Suhery; Hayu Lestari; Armon Fernando; Fina Aryani; Gressy Novita
Majalah Obat Tradisional Vol 28, No 2 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.84715

Abstract

Rice bran extract contains high antioxidant compounds. Formulation and antioxidant activity testing of cream preparations containing rice bran extract has been carried out. This study aims to formulate and evaluate cream preparations containing bran extract from two varieties of white rice and their antioxidant activity. The white rice varieties used were the Kalpatali variety (FI) and the Rice 64 (FII) variety. There were three cream formulas, namely the basic formula (F0) and the formula containing rice bran extract with a concentration of 3.1% each (FI and FII). Evaluation of cream preparations included organoleptic test, homogeneity, pH, washability, stability, irritation test, and antioxidant activity test. This study showed that FI has an antioxidant activity of 87.23% and FII has an antioxidant activity of 64.08%. Different varieties of rice show differences in antioxidant activity in cream preparations containing bran extract. The best formula is FI which has good physical properties and higher antioxidant activity compared to FII. 
FORMULASI DAN UJI ANTIOKSIDAN SEDIAAN GEL EKSTRAK DAUN MARPUYAN (Rhodamnia Cinerea Jack) Musyirna Rahmah Nst; Deni Anggraini Anggraini; Armon Fernando; Anita Lukman; Rajeb Fadillah
JURNAL KATALISATOR Vol. 8 No. 2 (2023): Jurnal Katalisator Volume 8 No. 2, Oktober 2023
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v8i2.2343

Abstract

Tumbuhan marpuyan merupakan jenis tumbuhan liar banyak tersebar di wilayah Indonesia. Secara empiris, marpuyan dimanfaatkan oleh masyarakat untuk berbagai pengobatan. Daun tumbuhan marpuyan berpotensi sebagai antioksidan. Hasil penelitian terdahulu melaporkan ekstrak etanol daun marpuyan mempunyai aktivitas tabir surya yang kuat. Formulasi sediaan topikal dalam bentuk gel lebih baik  karena memberikan efek nyaman dikulit. Tujuan penelitian ini adalah memformula ekstrak etanol daun marpuyan dalam bentuk sediaan gel dan menentukan aktivitas antioksidan. Formulasi gel ekstrak etanol daun marpuyan 3 variasi konsentrasi yaitu 0,5% (FI), 1% (FII) dan 2% (FIII). Pengujian aktivitas antioksidan dilakukan dengan menggunakan metode DPPH. Evaluasi gel meliputi pengamatan organoleptis, pH, homogenitas, uji stabilitas freeze and thaw, uji daya sebar, uji daya lekat dan uji iritasi. Hasil penelitian menunjukkan gel ekstrak etanol daun marpuyan memiliki aktivitas antioksidan yang sangat kuat pada FII (1%) dan FIII (2%). Hasil uji stabilitas menunjukkan gel gel ekstrak etanol daun marpuyan tidak stabil setelah disimpan 8 minggu dan tidak memenuhi persyaratan uji daya sebar.
UJI VALIDASI METODE DAN PENETAPAN KADAR RANITIDIN DALAM SEDIAAN TABLET SECARA SPEKTROFOTOMETRI UV: METHOD VALIDATION TEST AND DETERMINATION OF RANITIDINE CONTENT IN TABLET PREPARATIONS BY UV SPECTROPHOTOMETRY Dona, Rahma; Ningrum, Tilar Eka Widia; Nasution, Musyirna Rahmah; Fernando, Armon; Syahbandi, Ilham; Milianty, Jesy
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1805

Abstract

This study aims to determine the levels of ranitidine in generic and trade name tablet preparations by UV spectrophotometry. Based on the results obtained linearity value of r = 0.9999 with limit of detection (LOD) 0.1667 ppm and limit of quantitation (LOQ) 0.5558 ppm. Precision obtained RSD results of 0.641% and in accuracy obtained % recovery at 3 concentrations of 9, 12 and 15 ppm respectively 101.05; 100.63; and 100.33%. The results of the determination of levels in ranitidine tablet preparations with five generic tablets and five trade name tablets have met the requirements for levels in medicinal preparations for ranitidine tablet preparations according to the Indonesian Pharmacopoeia VI Edition, which contains ranitidine not less than 90.0% and not more than 110.0%. It can be concluded that the UV spectrophotometric method used in the study has met the parameters set in the validation test so that this method can be applied to the analysis of determining ranitidine levels in a laboratory. Keywords:  Ranitidine, UV Spectrophotometry, Method validation
Co-Authors Adriani Susanty agistia, nesa Agistia, Nesa Agustini, Tiara Tri Ainun Alfatma Allaya, Regina Alpatiqa, Silviana Lufti, Siti Hizra Amanda Yulia Amin, Syahrul Anita Lukman Annisa Safitri Arief, Encik Juliansyah Aulia, Nada Aqilah Azkia Wanudya Rahmadhani Benni Iskandar Buddy Giovanni DAYAR ARBAIN Deni Anggraini Dira Repuja Dwi Winarsih Elsa Safitri Enda Mora Fadhilatun Khoiriyah Farediah Ahmad Farisa, Nayla Al Ferdy Firmansyah Fina Aryani, Fina Fitri Suryani Furi, Mustika Gressy Novita Haiyul Fadhli Hariyani, Widya Hasnah M. Sirat Hayu Lestari Hefriza Putri Husnawati Ihsan Ikhtiarudin Indah Puspita Sari Indri Aprilia, Indri Irfan, Nawwar Ivona Adelin Jannati, Nisa Jumadila, Ikhsal Mukri Kolista Sisilawati M. Almurdani Maryunita, Dinda Mayrade, Salma Yudhistira Meiriza Djohari, Meiriza Melzi Octaviani Meyrika Putri Wandala Milianty, Jesy Muhtadi, Wildan Khairi Musyirna Rahmah Nst Neni Frimayanti Netralis Has Ningrum, Tilar Eka Widia Nofri Hendri Sandi Nurul Elisa Putri Lestari Putri Lestari, Putri Putri, Dhini Fahira Rahayu Utami Rahayu Utami Rahma Dona Rahma, Indah Lutfianti Rahma, Rizqia I’zza Rahmah, Rizka I’zaa Rahmayanı, Wıky Rajeb Fadillah Ramona, Paula Repuja, Dira Rickha Octavia Rusnedy, Rahmayati Sadam Husein Safira, Yola Safitri, Fasri Dian Septi Muharni Suci Bettiza Oktarisma Suhelmi - Suhelmi - Syafutri, Lidiyah Syahbandi, Ilham Syilfia Hasti Tengku Yuni Atika S Tiara Salsabila P.A Tita Adhaha F Venny Wulandari Victriani Sitohang Winda Sari Winda Windiati Wira Noviana, Wira Noviana Yeni Karlina Yulia, Amanda Yulius Mubharroq Zakiyah Manaf