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Sarifah Nurjanah
Fakultas Teknologi Industri Pertanian, Universitas Padjadjaran, Jawa Barat, Indonesia
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Journal : Gontor AGROTECH Science Journal

 1 
Antibacterial Activity of -guaiene Patchouli Oil on Staphylococcus aureus and Staphylococcus epidermidis Novia Dwi Anggraeni; Sarifah Nurjanah; Elazmanawati Lembong
Gontor AGROTECH Science Journal Vol 6, No 3 (2020): Special issue Seminar Nasional Sains dan Teknologi (SNST) 2020
Publisher : University of Darussalam Gontor, Ponorogo, East Java Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/agrotech.v6i3.4964

Abstract

Patchouli oil has the content of α-guaiene as one of the dominant components. The α-guaiene compound is one of the seskuiterpen groups that has antibacterial capabilities, but there have been no reports of antimicrobial activity of the α-guaiene compound. Staphylococcus aureus and Staphylococcus epidermidis bacteria are normal human microbials that often cause nosocomial infections (originating from hospital environments). This study aims to find out the antibacterial activity of α-guaiene with a purity of 37,50%. The method used is the test of the diameter of the well diffusion method against the bacteria S. aureus ATCC 25923 and S. epidermidis ATCC 12228. The study used variations in α-guaiene concentrations of 20%, 40%, 60%, 80%, and 100%. The α-guaiene material used is the result of the process of distillation fractionation of patchouli oil, so that it is obtained α-guaiene components with a purity of 37,50%. The results showed that the α-guaiene components with purity of 37,50% able to inhibit the growth of both test bacteria, with the highest antibacterial activity found in the bacteria S. aureus in concentration variation of 60% with an average resistance diameter value of 10,33 mm. In conclusion, α-guaiene components with purity of 37,50% indicate the existence of antibacterial activity.
Co-Authors Abdullah Md Zain Abil Fadila Ade Moetangad Kramadibrata Agil Firhan Iskandar Agnes Klarasitadewi Ahmad Thoriq Ainina, Nurul Akbar Hanif Dawam Abdullah, Akbar Hanif Dawam Anas Bunyamin Andina, Dwita Putri Andri Permana Annissa Ramadhanti Arinda Nur Ariva Asri Widyasant Asri Widyasanti Atiek Rostika Noviyanti Azizah, Ise Wafiq Bambang Nurhadi Boy Macklin Pareira Prawiranegara Budhi Indrawan David S. Marpaung Dedy Prijatna Dina Aprilia Dwi Merita Rosi Dwita Putri Andina E Gumbira-Sa’id - Efri Mardawati Eki Dwiyan Saputra Elazmanawati Lembong Ema Komalasari Etty Riani Fakhira, Qonita Raihani Fany Trihapsoro Farah Nuranjani Farah Nuranjani Fathia Salsabila Emmaputri Fawaiz, Husni Syamil Fitry Filianty Galih Adhi Respati Gumbira-Sa'id, E Handarto HARYONO Haryono Haryono Haryono Haryono Hilman Syaeful Alam Huda Nurul Quddus Ibrahim A. I. Ifmalinda Ilham Fajri Imas Siti Setiasih Indira Lanti Kayaputri Intan Aprilia Irene June Sidabutar Irmayanti, Maya Isti Sulistiani Jeremia Kristian Khaswar Syamsu Khaswar Syamsu - Kurnia, Ina Laily Rizki Safira Lita Fitriyani Khairunisa M. Ade Moetangad Kramadibrata Maya Damayanti Mimin Muhaemin Mochammad Rizal Mochammad Rizal Muhammad Gilang Ramadhan Muhammad Rizky Ramanda Muhammad Saukat Nadyah Rachma Dewi Namira, Tiara Nedia Cahyati Muchtarina Nedia Cahyati Muchtarina Nissa, Rossy Choerun Novia Dwi Anggraeni Nur Oktavia Benedicta Nuranjani, Farah Nurfauziah, Isni Nurpilihan Bafdal Nurul Ainina Nurul Ainina Pirdani Nur Fitri Prisilia Ratna Setyaningrum Puji Lestari Pusponegoro, Annisa Putri, Farinissa Deliana Qurratu’ain, Yona Rahmawati, Rahmi Reza Permana Aji Rienoviar Rienoviar Rienoviar, Rienoviar Rifki Amrullah Rizika Wulandari Rizky Mulya Sampurno Rizqi Putri Fathoni Rosalinda, Sari Roshita Ibrahim Rudi Adi Saputra Ruth Anggia Assyera S Rosalinda S. Rosalinda S. Rosalinda S. Rosalinda S. Rosalinda, S. S.Rosalinda Rosalinda Salman Hafidz Sarinarulita Rosalinda Sekar Widyaningrum Selly Harnesa Putri Septianti, Nur Alifa Shayana Junita Sudaryanto Zain Sudaryanto Zain Sudaryanto Zain Sudaryanto Zain Suprihatin - Suprihatin Suprihatin Thoriq, Ahmad Tio Febriananda Tita Rialita Totok Herwanto Totok Pujianto Totok Pujiyanto Wahyu Daradjat Wahyu Kristian Sugandi Widyaningrum, Sekar Yati B Yuliyati Yati B. Yuliyati Yeyen Nurhamiyah, Yeyen Yona Qurratu’ain Zahrah Eza Arpima Zhaqqu Ilham Alhafidz Zulfaa Irbah Zain ‪Irna Dwi Destiana