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The Efficacy Study of Duramectin, Oxfendazole, Piperazine, and Pyrantel pamoate Against Gastrointestinal Worms In Horses In Yogyakarta Special Region*) Yuriadi Yuriadi; Ida Tjahajati; Soedarmanto Indarjulianto; Irkham Widiyono
Jurnal Sain Veteriner Vol 37, No 1 (2019): Juni
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (528.394 KB) | DOI: 10.22146/jsv.42969

Abstract

This research aimed at determining the efficacy of duramectin, oxfendazole, piperazine, and pyrantelpamoate against gastrointestinal worms in horses in Yogyakarta Special Region and Central Java. The object of research involved 40 horses diagnosed with gastrointestinal worm infection. Prior to the research, all of the horses were subjected to examination for clinical symptoms and parasitology laboratory checkup for signs of worm eggs in their feces, and they were pronounced positive for experiment animals with at least 150 eggs per gram of feces per horse. The research horses were weighed to determine the dose of worm medication to be used. The research horses are divided into four treatment groups, each group consists of ten horses. Group I was given duramectin with a dose of 0.2 mg/kg of body weight. Group II was given oxfendazole with a dose of 7.5 mg/kg of body weight, Group III was given 125 mg Piperazin treatment per kilogram of body weight and Group IV was given pyrantelpamoate with a dose of 20 mg/kg of body weight. After receiving themedication, the horses were observed to document the progress in terms of clinical symptoms and the amount and type of worm eggs in their feces every three days for four times in a row. The research data results were tabulated and were descriptive-comparatively analyzed.The research result showed varying efficacy level of worm medication for horses. Oxfendazole kills Strongylus and Parascaris worms. Duramectin kills Strongylus worms and reduce some of the Parascaris worms. Piperazineandpyrantelpamoate kills the Strongylus wormsand reduce some of the Parascaris. 
Effectiveness of Gout Therapy with Polyherbal Extract of Shallot (Allium ascalonicum L.) and Red Ginger (Zingiber officinale var rubrum) in Hyperuricemia Mice Fathur Rohman Haryadi; Dela Ria Nesti; Ida Tjahajati; Okti Herawati
Jurnal Sain Veteriner Vol 38, No 2 (2020): Agustus
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.51360

Abstract

Gout can cause inflammation of acute gout arthtritis, as well as other complications. Provision of chemical drugs in the long term have side effects. Shallots (Allium ascalonicum L.) contain flavonoids which can inhibit the xanthine oxidase enzyme, so as to reduce uric acid levels. Red ginger extract (Zingiber officinale var rubrum) is rich in gingerol to reduce uric acid with anti-inflammatory effect. Polyberbal combination is expected to increase the effectiveness of therapy. The research aims to determine the effectiveness of polyherbal combinations. 25 male rats (2-3 months) were divided into five groups, namely negative control, positive control, (P1) 25% red ginger extract: 75% shallot, (P2) 50% red ginger extract: 50% shallot, ( P3) 75% red ginger extract: 25% shallot. Induction of potassium oxonate 250 mg / kg BW intraperitoneally on the 7th day. The first measurement of uric acid on the 14th day with Urid Acid Toos, the 15th to 28th days was administered herbal / chemical drugs according to the group. Measurement of second and third uric acid on days 21 and 28. Data were analyzed by one-way Anova (RAL), further significance tests using Least Significant Different (LSD). The results showed that administration of potassium oxonate and combination of herbal extracts had a significant effect (p <0.05) on uric acid levels in all groups. The most effective herbal combination doses are (P3) 75% red ginger (450 mg / 200 gr) and 25% shallot (150 mg / 200 gr BW). The conclusion of this study is the combination of red ginger extract and shallot can be recommended as a uric acid-lowering agent.
Efficacy of Albendazole Against Strongylus sp. and Hematology Changes on Equine in Yogyakarta Special Region yuriadi yuriadi; Ida Tjahajati; Guntari Titik Mulyani; Kelviano Muqit; Aidah Rahmanita
Jurnal Sain Veteriner Vol 39, No 2 (2021): Agustus
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.60110

Abstract

The infestation of Strongylus sp. in horses can cause losses to horse breeders, including anorexia, anemia, gastrointestinal diseases and can cause death and decrease the horse population in DIY. Albendazole was a Benzimidazole preparation that is often used to treat worms in ruminants. This study also aims to determine the effect of Albendazole on blood images before and after treatment. The material used in this study were 10 horses with male and female sex,  over 3 years old, and infected with Strongylus sp. with an infestation rate of 200 EPG in faeces. Before treatment of drug was carried out, the faeces was examined with Mc Master method. After treatment with Albendazole, the worm eggs were examined three times at intervals of three days. Routine examination of worm eggs and blood was carried out at the Laboratory of the Department of Internal Medicine, Faculty of Veterinary Medicine, Universitas Gadjah Mada. The results showed that the EPG number decreased from the 0th, 3rd, 6th and 9th day of examinations. The average number of EPG on the 0th day was 990 eggs/gram, and the examination on the 9th day showed the number of eggs was 0 eggs/gram. The results of the hematology examination also showed no significant difference except for the high number of eosinophils on the 12th day after drug administration. The conclusion from this research is that Albendazole as a worm medicine can kill Srongylus sp. however, it does not affect the horse's hematology and health status.
Produksi Antibodi Anti-Dirofilaria immitis Untuk Pengembangan Diagnosis Dirofilariasis Pada Anjing I Gusti Made Krisna Erawan; Ida Tjahajati; Wisnu Nurcahyo; Widya Asmara
Buletin Veteriner Udayana Vol. 8 No. 2 Agustus 2016
Publisher : The Faculty of Veterinary Medicine, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (60.612 KB)

Abstract

Dirofilaria immitis (D. immitis) as a causative agent of heartworm disease is not only caused problems in animals but also zoonoses. For diagnosis of dirofilariasis (disease caused by D. immitis) serologically is needed anti-D. immitis antibodies. The objective of this study was to produce antibodies against excretory-secretory antigens produced by male and female worms for developing the diagnosis of dirofilariasis based on the antigens detection. Base on this study can be concluded that male excretory-secretory antigens (MES), female excretory-secretory antigens (FES), and MES+FES can stimulate BALB/c mouse to produce polyclonal antibodies in the same pattern. Antibodies have been produced at day 21 and the peak titter was at day 35 after first immunization.
Prevalensi dan Faktor Risiko Infeksi Dirofilaria immitis pada Anjing yang Dipotong di Daerah Istimewa Yogyakarta (PREVALENCE AND RISK FACTOR OF THE DIROFILARIA IMMITIS INFECTION IN DOGS SLAUGHTERED IN DAERAH ISTIMEWA YOGYAKARTA) I G. Made Krisna Erawan; Ida Tjahajati; Wisnu Nurcahyo; Widya Asmara
Jurnal Veteriner Vol 18 No 4 (2017)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (98.758 KB) | DOI: 10.19087/jveteriner.2017.18.4.541

Abstract

The aim of this study was to determine the prevalence and risk factors Dirofilariaimmitis (D. immitis) infection in dogs slaughtered in Yogyakarta. A total of 151 dogs that were slaughtered from May – November 2013 were examined their heart in order to determine the presence of D. immitis infection. Blood samples were tested using Modified Knott’s Technique for microfilariae examination. The results showed that based on the heart and blood examination the prevalence of D. immitis infection was 14.6 % and 7.9 %, respectively. The risk factors for D. immitis infection were the age and origin of the dog.
Antigen Ekskretori-Sekretori Cacing Jantung (Dirofilaria immitis) Jantan dan Betina yang Berpotensi Sebagai Marka Diagnosis (EXCRETORY-SECRETORY ANTIGENS OF MALE AND FEMALE HEART WORMS (DIROFILARIA IMMITIS) WHICH POTENTIALLY AS A DIAGNOSTIC MARKER) I Gusti Made Krisna Erawan; Ida Tjahajati; Wisnu Nurcahyo; Widya Asmara
Jurnal Veteriner Vol 16 No 4 (2015)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.95 KB)

Abstract

Heart worm (Dirofilaria immitis) is the causative agent of a serious parasitic disease in dogs.Dirofilariasis is generally diagnosed by microfilariae examination and specific antigen testing. Microfilariaeexamination has low sensitivity due to occult infections. The available antigen test at this time is able todetect circulating antigens secreted by adult female worms only. The aim of the present study was toidentify male (MES) and female (FES) heart worms excretory-secretory antigens which have the potentialas a diagnostic targets. Identification of antigen was done by sodium dodecyl sulphate polyacrylamide gelelectrophoresis (SDS-PAGE) and Western Blotting analysis. The results of this study indicated that therewere differences between the MES and the FES profiles. The results showed 12 bands in MES (14–118kDa) and 18 bands in FES (10–205 kDa). Protein with a molecular weight of 59 kDa has the potential asdiagnostic markers of dirofilariasis.
Sosisalisasi Kesehatan Hewan Kepada Masyarakat Secara Daring: Online Socialization of Animal Health to The Community Soedarmanto Indarjulianto; Yanuartono Yanuartono; Slamet Raharjo; Alfarisa Nururrozi; Hastari Wuryastuty; Irkham Widiyono; Hary Purnamaningsih; Guntari Titik Mulyani; Ida Tjahajati; Sri Hartati; Yuriadi Yuriadi
IGKOJEI: Jurnal Pengabdian Masyarakat Vol. 2 No. 2 (2021): IGKOJEI: Jurnal Pengabdian Masyarakat
Publisher : Fakultas Peternakan Universitas Papua

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46549/igkojei.v2i2.223

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ABSTRACT Various animal diseases are not always known by animal owners, so they must always be socialized even in the condition of the COVID-19 outbreak. This community service aims to provide animal health information to the community by online. This activity was carried out from in November 2020 using the Cisco Webex platform. The results showed that as many as 269 participants have joined in the socialization, consisting of 180 from Yogyakarta and 89 from outside Yogyakarta. Concluded that online socialization of animal health is successfully carried out and received a very good response from the community. Keywords: Animal health; Community service; Veterinary clinic ABSTRAK Berbagai macam penyakit hewan tidak selalu diketahui oleh pemilik hewan, sehingga harus selalu disosialisasikan walapun dalam kondisi wabah COVID-19. Pengabdian kepada masyarakat (PKM) ini bertujuan memberikan informasi kesehatan hewan kepada masyarkat secara daring. Pengabdian dilakukan pada bulan bulan Oktober sampai Nopember 2020 secara daring menggunakan platform Cisco Webex. Hasil PKM menunjukkan bahwa sebanyak 269 calon peserta telah mengikuti sosialisasi, yang terdiri dari 180 berasal dari Yogyakarta dan 89 dari luar Yogyakarta. Berdasar hasil kegiatan ini, disimpulkan bahwa sosialisasi tentang kesehatan hewan secara daring berhasil dilaksanakan dan mendapat respon sangat bagus dari masyarakat. Kata kunci: Kesehatan hewan; Klinik hewan; Pengabdian masyarakat.
Deteksi Penyakit Zoonosis Ehrlichiosis pada Pasien Anjing di Klinik Hewan Jogja Dela Ria Nesti; Ahmad Baidlowi; Febri Ariyanti; Ida Tjahajati
Jurnal Nasional Teknologi Terapan (JNTT) Vol 2, No 2 (2018): JULI
Publisher : Penelitian dan Pengabdian Kepada Masyarakat Sekolah Vokasi Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (114.646 KB) | DOI: 10.22146/jntt.42966

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Ehrlichiosis is a zoonotic diseases caused by blood parasitic infection that can be transmitted by a ticks. Dogs infected with Ehrlichiosis canis who not treated for long periods of time can cause anemia and result in death. Although many diseases are found in the field but the percentage rate of the incidence of the disease is unknown. This study aims to detect Ehrlichiosis disease in dog patients treated at Jogja Veteinary Clinic by using Ehrlichiosis diagnosis kit available in the field. The material used in this study used dog patients who came to the Jogja Veterinary Clinic during April to September 2017. Dog patients who showed signs of infection of blood parasites with clinical symptoms of appetite and drinking down, weak, lethargic, found the presence of a ticks, or there history of infected ticks was included in the study. Patients who entered the study criteria, then taken the blood through the vena cephalika by using a 3 ml sterile syringe. Furthermore, fresh blood drops on the Ehrlichiosis detection kit according to the manufacturer's instructions. Furthermore, the results are positive if found two lines and negative when only seen one line. Data of research result are presented in tabular form and percentage of disease according to result obtained. The results of the research showed that there were 7,63% (15/1,785) positive dogs suffering from Ehrlichiosis. These results can illustrate the incidence of Ehrlichiosis in dogs, especially in dog patients treated at the Jogja Veterinary Clinic, because of the danger of Ehrlichiosis (zoonotic), awarness is needed.
Survei Ancylostomiasis pada Anjing di Wilayah Daerah Istimewa Yogyakarta Gustaf Eifel Silalahi; Ida Tjahajati; Widagdo Sri Nugroho
Acta VETERINARIA Indonesiana 2022: Special Issues
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avi...49-53

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Selama masa pandemi Covid-19, mayoritas masyarakat Indonesia menghabiskan hampir seluruh waktunya di rumah. Waktu interaksi antara pemilik dan hewan peliharaan di rumah semakin banyak dihabiskan bersama. Namun, di satu sisi terdapat risiko penularan penyakit dari hewan peliharaan seperti anjing ke manusia. Penyakit yang sering dilaporkan pada anjing adalah ancylostomiasis. Ancylostoma spp. umumnya dikenal sebagai "cacing tambang" dari golongan nematoda. Gejala klinis penyakit ancylostomiasis tidak spesifik karena agen infeksi memiliki siklus hidup dan periode infeksi. Hal ini menjadi perhatian karena tidak adanya gejala yang spesifik sehingga ada potensi infeksi yang tidak terdeteksi pada hewan peliharaan. Penelitian ini bertujuan untuk mengetahui proporsi penyakit ancylostomiasis pada anjing yang dipelihara oleh masyarakat di wilayah Daerah Istimewa Yogyakarta. Penelitian ini dilakukan dengan pendekatan survei dengan melibatkan sampel anjing sebanyak 203 ekor anjing. Spesimen yang dikoleksi berupa feses dari anjing jantan dan betina berbagai umur di wilayah Daerah Istimewa Yogyakarta. Pemeriksaan sampel feses dilakukan dengan menggunakan metode kualitatif (metode natif) untuk mengidentifikasi telur dari cacing. Total kasus helminthiasis yang teridentifikasi dari pemeriksaan sampel feses berjumlah 19 dari total 203 anjing. Prevalensi telur Ancylostoma spp. adalah 6,89% (14 dari total 203 anjing). Telur cacing yang teridentifikasi menginfeksi adalah telur cacing spesies Ancylostoma spp. (6,89%) Toxocara spp. (1,97%) dan Dipylidium spp. (0,98%). Proporsi penyakit ancylostomiasis di Daerah Istimewa Yogyakarta pada survei penelitian ini ditemukan 6,89%.
Diagnosis dan Pengobatan Babesiosis pada Anjing Shih-Tzu di Klinik Lilipoet, Yogyakarta, Indonesia Nabilah Putroe Agung; Dwi Priyowidodo; Ida Tjahajati; Lily Gunawan
Jurnal Sain Veteriner Vol 40, No 3 (2022): Desember
Publisher : Fakultas Kedokteran Hewan Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.74202

Abstract

Dogs are one of the pet animals that have a loyal nature and are widely cared for in the community. It is not uncommon for dogs to often play in parks or outdoor environments that are surrounded by grass to play with their owners. The grass is a breeding ground for ticks, which can be vectors of disease carriers for dogs. Babesiosis is a disease caused by Babesia sp. and is transmitted by tick vectors. In this paper, we will discuss the clinical condition, diagnosis, and treatment of one dog with babesiosis at the Lilipoet clinic, Yogyakarta. A Shih-Tzu dog has clinical symptoms of fever with a temperature of 39.9oC, decreased appetite, and has a history of yellow vomiting, and found one tick. Blood was collected for microscopic examination of blood smears, blood hematologic, and molecular examination. Hematologic examination of the blood showed the value of thrombocytopenia with a value of 32 x 103/µL. Molecular examination with Polymerase Chain Reaction (PCR) showed positive results of Babesia sp. with visible DNA bands at 490bp. Treatment was carried out by giving one dose of antiprotozoal diminazen aceturate 3.5 mg/kg BW and doxycycline 10mg/kg BW once a day for 14 days.
Co-Authors Achmad Fauzi Adellyna Chrissandra Adi Utarini Ahmad Baidlowi Ahmad Baidlowi Aidah Rahmanita Akbar Wicaksono Alan Chandrasaputra Albert Jackson Yang Alfarisa Nururrozi Alfarisa Nururrozi, Alfarisa Alfariza Nururozi Angeline Ganapragasam Anggi D Prayitno Aris Haryanto Aris Haryanto Asri Rizky Bagas Pria Prasetyo Baidlowi, Ahmad Bambang Hariono Begum F R Aditya Budiono Santoso Datrianto, Dwi S. Decline , Vega Dionisius M. . Dwi Priyowidodo Dzul Himam Isnan Ali E Rrarindah Fa&#039;iz Ihsanul Kamil Farhan Arhabi Prima Fathur Rohman Haryadi Febri Ariyanti Guntari Titik Mulayni Guntari Titik Mulyani Gustaf Eifel Silalahi Gustaf Eifel Silalahi Hardyanto Soebono Hardyanto Subono Harjono, Habib Prasetyo Hary Purnamaningsih Hary Purnamaningsih Hastari Wuryastuty Hastari Wuryastuty Hastari Wuryastuty Hastari Wuryastuty Herawati, Okti I Gusti Made Krisna Erawan Imron Rosyadi Indarjulianto , Soedarmanto Irkham Widiyono Kelviano Muqit L Rifiyanta Laksono Trisnantoro Lily Gunawan M A Candra Moch Dea Zein Muh. Disna Faizal Muhammad Fatkhurohman Muhammad Rosyid Ridlo Muhammad Zulfadhillah Sinusi Nabilah Putroe Agung Nesti, Dela Ria Nobuyuki Harada Pamudya, Kanya Gabriella Sasri Pramono, Agung Budi Raden Wisnu Nurcahyo Rahayu , Pudji Retno Widyastuti, Retno S I Astuti Slamet Rahardjo Slamet Raharjo Slamet Raharjo Slamet Raharjo Soedarmanto Indarjulianto Soedarmanto Indarjulianto Soedarmanto Indarjulianto Soedarmanto Indarjulianto Soedarmanto Indarjulianto Sri Hartati Sri Hartati Sri Hartati Sri Indah Astuti Subronto Prodjoharjono Subronto Prodjoharjono Sukma, Salsabila Ayuningtyas T A Widiastuti Tri Ari Widiastuti Tri Ayu Widiastuti Viastika , Yanita Mutiaraning Wardani , Sundika Wibisono, Cahyo Wibowo , Sarwo Edy Widagdo Sri Nugroho Widiasih , Dyah Ayu Widya Asmara Wijayanti , Agustina Dwi Wisnu Nurcahyo Yanuartono Yanuartono Yanuartono Yanuartono Yanuartono, Yanuartono Yeo Suan Jiao Yuriadi . Yuriadi Yuriadi Yuriadi Yuriadi Yuriadi Yuriadi Yuriadi Yuriadi, Yuriadi Yustinus Oswin Primajuni Wuhan