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All Journal ComEngApp : Computer Engineering and Applications Journal VALENSI JURNAL KIMIA SAINS DAN APLIKASI Jurnal Riset Kimia ICON-CSE CHEMPUBLISH JOURNAL Jurnal Sains dan Teknologi Pangan ALCHEMY Jurnal Penelitian Kimia Indonesian Journal of Chemistry Jurnal Penelitian Farmasi Indonesia Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) Molekul: Jurnal Ilmiah Kimia Jurnal Ilmu Kefarmasian Indonesia Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Jurnal Dunia Farmasi Cendekia Journal of Pharmacy Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia Cendekia Medika : Jurnal Stikes Al-Ma`arif Baturaja Action Research Literate (ARL) COVIT Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Jurnal Kesehatan Farmasi Jurnal Farmasi Indonesia Molekul: Jurnal Ilmiah Kimia JPS (Jurnal Pharma Saintika) BATOBO: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Borneo Journal of Pharmacy Journal Of Pharmacy
Neni Frimayanti
Sekolah Tinggi Ilmu Famasi Riau
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Sintesis Dan Studi Molecular Docking Senyawa Pirazolo-Piridin Turunan Analog Kurkumin Monoketon Sebagai Inhibitor Enzim COX-2 Enda Mora; Adel Zamri; Hilwan Y. Teruna; Neni Frimayanti; Ihsan Ikhtiarudin; Putri Rizki Rahmadani; Vella kurnia Wahyuni
Jurnal Penelitian Dan Pengkajian Ilmiah Eksakta Vol 1 No 2 (2022): Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE
Publisher : LPPM Universitas Dharma Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47233/jppie.v2i1.799

Abstract

The new pyrazolo-pyridine compounds derived from monoketone curcumin analogues (P4Cl and P2CL) were synthesized in two stages. The first stage was the synthesis of curcumin monoketone (Cs) analogue through the Claisen-Schmidt reaction in the heating method using reflux. The second step was the synthesis of P2CL and P4Cl through nucleophilic addition and intramolecular cyclization in the heating method using a Monowave 50 apparatus. The structures of the compounds P2CL and P4Cl were confirmed by spectroscopic analysis including UV-Vis, FT-IR, 1H-NMR and HRMS. Based on molecular docking studies, the compounds P2Cl and P4Cl have weak potential as COX-2 enzyme inhibitors with a binding free energy value of -4.02 kcal/mol and an RMSD of 1.19.
SINTESIS DAN STUDI MOLECULAR DOCKING SENYAWA PIRAZOLO-PIRIDIN TERSUBSTITUSI METOKSI TURUNAN KURKUMIN MONOKARBONIL SEBAGAI INHIBITOR ENZIM SIKLOOKSIGENASE-2 Enda Mora; Adel Zamri; Hilwan Yuda Teruna; Neni Frimayanti; Ihsan Ikhtiarudin; Shafira Melsonia
Jurnal Penelitian Farmasi Indonesia Vol 12 No 1 (2023): JPFI
Publisher : Pusat Penelitian dan Pengabdian Masyarakat (P3M) Sekolah Tinggi Ilmu Farmasi Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51887/jpfi.v12i1.1763

Abstract

Scaffold pirazol maupun piazolo-piridin telah dilaporkan memiliki potensi aktivitas biologis yang menarik dan terdapat pada berbagai struktur senyawa obat yang telah disetujui oleh food and drug administration (FDA). Pada penelitian ini, senyawa pirazolo-piridin tersubstitusi metoksi sebagai turunan dari analog kurkumin monokarbonil telah disintesis melalui dua tahap reaksi. Tahap pertama adalah sintesis analog kurkumin monokarbonil tersubsitusi metoksi melalui reaksi kondensasi Claisen-Schmidt dengan bantuan iradiasi microwave. Tahap kedua adalah sintesis senyawa pirazolo-piridin melalui reaksi adisi nukleofilik yang diikuti oleh reaksi siklisasi intramolekular dalam reaktor tertutup, monowave 50. Kemurnian produk hasil sintesis telah dipastikan melalui analisis HPLC. Struktur senyawa pyrazolo-piridin telah dikonfirmasi melalui analisis spektroskopi UV-Vis, FT-IR, dan 1H-NMR. Berdasarkan studi molecular docking, senyawa tersebut  tidak menunjukkan potensi aktivitas yang baik sebagai inhibitor enzim siklooksigenase-2 (COX-2), karena hanya memiliki nilai energi bebas pengikatan sebesar -5,98 kcal/mol. Selain itu, pirazolo piridin tersubstitusi metoksi juga tidak dapat membentuk satupun ikatan hidrogen dengan sisi aktif COX-2. Di sisi lain, celecoxib sebagai kontrol positif memiliki energi bebas pengikatan sebesar -11,97 kcal/mol dan dapat membentuk ikatan hidrogen dengan residu asam amino Gln178, Leu338, Arg499, dan Phe504 pada sisi aktif COX-2 (PDB ID: 3LN1). Pyrazol and pyrazolopyridine scaffolds have been reported to have many interesting biological activities and present in various structures of drug compounds that have been approved by the food and drug administration (FDA). In this study, a methoxy-substituted pyrazolo-pyridine compound as derivative of monocarbonyl curcumin analogs was synthesized in two steps of reaction. The first step was the synthesis of monocarbonyl curcumin analog through the Claisen-Schmidt condensation with the assist of microwave irradiation. The second step is the synthesis of pyrazolopyridine through nucleophilic addition followed by intramolecular cyclization in a closed-vessel reactor, monowave 50. The purity of synthesized product was confirmed by HPLC analysis, and the structure has been confirmed through UV-Vis, FT-IR, and 1H NMR spectroscopic analyses. Based on the molecular docking study, the pyrazolo-pyridine did not show good activity as cyclooxygenase-2 (COX-2) inhibitor, because it only has a binding free energy of -5.98 kcal/mol. In addition, methoxy-substituted pyrazolo-pyridin also can not form any hydrogen bonds with the active site of COX-2. On the other hand, celecoxib as a positive control has a binding free energy of -11.97 kcal/mol and can form hydrogen bonds with Gln178, Leu338, Arg499, and Phe504 amino acid residues on the active site of COX-2 (PDB ID: 3LN1).
Isolation of Endophytic Fungus from Leaves of Uncaria cordata (Lour.) Merr and Antibacterial Activity Against Propionibacterium acnes and Escherichia coli Melzi Octaviani; Winda Yusma Ameliah; Neni Frimayanti; Meiriza Djohari; Haiyul Fadhli
Borneo Journal of Pharmacy Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i3.3692

Abstract

Uncaria cordata (Lour). Merr (akar kaik-kaik) is one of the medicinal plants used as antibacterial because it contains bioactive compounds that can inhibit the growth of microorganisms. The plant is one of the sources of endophyte fungal isolates that can be developed as an alternative to producing antibacterial compounds. This research aimed to isolate the endophytic fungus from the leaves of U. cordata and know the antibacterial activity against Propionibacterium acnes and Escherichia coli by disc diffusion. The Fungi that were isolated from the leaves of U. cordata were 17 isolates. The isolates were continued for antibacterial activity testing: IFED 1 (Nigrospora sp.), IFED 2 (Aspergillus sp.), IFED 3 (Fusarium sp.), and IFED 4, whose genus was unknown. The results obtained were fungal isolates IFED 1 to IFED 4 had activity in inhibiting the growth of P. acnes with moderate category (18.16 mm) and weak categories (6.21, 6.16, and 6.68 mm) and in E. coli with moderate category (14.56 mm) and weak categories (6.53, 6.71, and 7.23 mm). The results of One-Way ANOVA and Tukey's test showed a significant difference (p <0.05) between the diameter of the inhibition zone with the type of endophytic fungus supernatant isolated from the leaves of U. cordata. The best isolate of endophytic fungi inhibiting P. acnes and E. coli bacteria was IFED 1 (Nigrospora sp).
Docking and Molecular Dynamic Simulations Study to Search Curcumin Analogue Compounds as Potential Inhibitor Against SARS-CoV-2: A Computational Approach Neni Frimayanti; Adel Zamri; Yum Eryanti; Noval Herfindo; Veza Azteria
Jurnal Kimia Sains dan Aplikasi Vol 24, No 3 (2021): Volume 24 Issue 3 Year 2021
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2297.983 KB) | DOI: 10.14710/jksa.24.3.85-90

Abstract

Coronavirus is a pandemic in the world. It requires researchers and scientists to work hard to find a vaccine or drug to inhibit the development of the coronavirus. Many drugs have been used, such as remdesivir, lopinavir, and chloroquine. However, how effective is the use of these drugs for inhibiting the coronavirus’s growth? There is no research has been done. Curcumin is now known as one of the compounds that have some biological activities, and it is also can potentially be used as a CoV-2 inhibitor. The computational study, i.e., molecular docking and molecular dynamic, can help researchers to predict which compounds have the potential as an inhibitor against the CoV-2 coronavirus. In this study, lopinavir was used as a positive control. Lopinavir and 45 curcumin analog compounds were docked against the main protease protein with 6LU7 PDB ID. Based on the docking results, it was discovered that compound 1, compound 2, and compound 4 have the same binding orientation as lopinavir. Molecular dynamic simulation with the lowest binding free energy conformation was used to check these compounds’ stability. Only compound 4 was maintained to observe hydrogen bonding with Lys5 and Lys137 with a distance of 2.9 Å. The distance of hydrogen bonds and binding free energy over simulation time is essential to elucidate the potential compound’s affinity. For then, compound 4 can be used as a potential inhibitor against the CoV-2 coronavirus.
In Silico Analysis for Exploring the Potential Inhibitors Against Breast Cancer (MCF7) Using Curcumin Analogue Compounds Neni Frimayanti; Adel Zamri; Yum Eryanti
Jurnal Kimia Sains dan Aplikasi Vol 27, No 6 (2024): Volume 27 Issue 6 Year 2024
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.27.6.250-257

Abstract

Breast cancer is one of the most problematic diseases in the world. Currently, there are no potential vaccines for the treatment of this disease. Therefore, finding effective compounds, such as curcumin analogs, is crucial to inhibit breast cancer. Forty-five synthesized curcumin analogs were tested on the MCF7 cell line using the MTT assay. It was shown that nine curcumin compounds, Cpd 5, Cpd 9, Cpd 17, Cpd 18, Cpd 21, Cpd 25, Cpd 28, Cpd 32, and Cpd 45, had better inhibitory activities against breast cancer. Furthermore, in silico analysis was developed using 2D and 3D QSAR models with high predictive ability, with an r2 value of 0.834. In addition, based on molecular docking, molecular dynamics, and pharmacophore results, it was shown that these nine compounds had the lowest binding free energy and were also stable during the simulation. The presence of methoxy groups, hydrogen bond donors, and aromatic ring features are the main factors that enhance the biological activity of curcumin analogs. Therefore, these compounds could serve as references for the next stage of drug design.
Synthesis and Evaluation of Some Sulfonamide-Substituted of 1,3,5-Triphenyl Pyrazoline Derivatives as Tyrosinase Enzyme Inhibitors Herfindo, Nofal; Frimayanti, Neni; ikhtiarudin, Ihsan; eryanti, Yum; zamri, Adel
Molekul Vol 18 No 2 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.2.6936

Abstract

Pyrazoline is well-known as heterocycles compound that can exhibit many biological effects. In this work, we synthesized a series of sulfonamide-substituted 1,3,5-triphenyl pyrazoline compounds as a promising tyrosinase inhibitor agent. These compounds prepared by multicomponent reaction of corresponding aldehyde, ketone, and hydrazine using seal-vessel reactor. Pyrazolines compound were tested for their tyrosinase inhibitor activity through in vitro assay. The test result found that compound 4c, 4d, and 4e possessed better tyrosinase inhibitory activity compared to the reference drug, kojic acid. Compound 4c exhibited the strongest tyrosinase inhibitory effect with an IC50 value of 30.14 µM. The results suggested that hydroxyl and methoxy substituent at para position are preferable. Furthermore, molecular docking studies result match the pattern of in vitro assay where the compound will provide a stronger binding interaction and lower binding free energies.
GASKEN (Gerakan Anti Stunting wujudKan kEsehatan Nasional) Balita Bersama MAMAKU Frimayanti, Neni; Octavia, Rickha; Rusnedy, Rahmayati; Bella Parina, Ana; Efendi, Apriyani; Salsabila, Aulia; Anfasa Mashudi, Fristio; viola Afrilizetira, Garnis; Elvi Khairani, Mai; Kurniawan Putri, Nurafika; Qurnia Pratiwi, Putri; Zafarani, Welly; Lestari, Widya; Wulandari, Zertiks
BATOBO: Jurnal Pengabdian Kepada Masyarakat Vol 2 No 2: BATOBO: Desember 2024
Publisher : Jurusan Teknik Elektro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/batobo.2.2.79-87

Abstract

Pengabdian kepada masyarakat ini dilaksanakan di Dusun II Botiong, Desa Kuapan, Kecamatan Tambang, Kabupaten Kampar, Provinsi Riau dengan sasarannya masyarakat yang ada di desa tersebut. Pengabdian ini bertujuan agar masyarakat dapat mengetahui dan memahami tentang stunting dan cara pencegahannya. Diharapkan dengan program pengabdian masyarakat ini dapat mencegah tejadinya stunting dan dapat meningkatkan derajat kesehatan masyarakat. Pengabdian ini dilaksanakan pada hari Minggu, 22 Oktober 2023 dan diikuti oleh 50 masyarakat Desa Kuapan. Bentuk kegiatan berupa edukasi melalui door to door dengan pemberian leaflet sebagai media edukasi. Adapun untuk mengetahui tingkat pengetahuan masyarakat desa maka dilakukan pemberian lembar ceklis pretest dan posttest. Hasil dari analisis pengaruh perubahan skor pengetahuan pada saat pretest dan posttest menggunakan uji Wilcoxon. Hasil uji Wilcoxon menunjukkan p value sebesar 0,000 dimana nilai tersebut lebih kecil dari 0,05 sehingga dapat ditarik kesimpulan bahwa ada pengaruh yang signifikan antara pretest dan posttest pengetahuan responden. Kegiatan pengabdian masyarakat oleh Sekolah Tinggi Ilmu Farmasi Riau berjalan dengan baik karena adanya peningkatan pengetahuan masyarakat  sesudah penyuluhan dibandingkan sebelum penyuluhan.
Studi In Silico, Sintesis, dan Uji Sitotoksik Senyawa P-Metoksi Kalkon terhadap Sel Kanker Payudara MCF-7 Dona, Rahma; Frimayanti, Neni; Ikhtiarudin, Ihsan; Iskandar, Benni; Maulana, Fikri; Silalahi, Nova Tantri
JSFK (Jurnal Sains Farmasi & Klinis) Vol 6 No 3 (2019): J Sains Farm Klin 6(3), Desember 2019
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.6.3.243-249.2019

Abstract

Kalkon (1,3-difenil-2-propene-1-on) adalah salah satu senyawa golongan flavonoid yang memiliki beragam aktivitas biologis diantaranya sebagai antikanker. Penelitian ini bertujuan untuk mengetahui  efek sitotoksik analog kalkon (E)-3-(4-metoksifenil)-1-fenilprop-2-en-1-on dengan menggunakan teknik komputerisasi (docking), senyawa analog kalkon tersebut disintesis menggunakan reaksi kondensasi Claisen-Schmidt dengan katalis basa secara metode iradiasi gelombang mikro. Studi in silico ini dilakukan antara senyawa kalkon dengan  protein dengan kode PDB ID P521 dengan menggunakan program AutoDock Vina, sedangkan uji aktivitas sitotoksik senyawa kalkon dilakukan terhadap sel kanker payudara MCF-7 menggunakan metode WST-8. Berdasarkan hasil docking, senyawa kalkon (E)-3-(4-metoksifenil)-1-fenilprop-2-en-1-on memiliki potensi sebagai penghambat aktif terhadap sel kanker payudara MCF-7 ditandai dengan senyawa ini memiliki nilai energi bebas ikatan yang lebih kecil dibandingkan doxorubicin sebagai pembanding; memiliki 4 persamaan asam amino dengan doxorubicin dimana interaksi yang terbentuk terdiri dari 4 jenis ikatan yaitu ikatan hidrogen, ikatan van der Waals, ikatan pi-sigma dan ikatan pi –alkil.  Dari hasil uji sitotoksik antara sel kanker MCF-7 dan senyawa kalkon diperoleh nilai IC50 sebesar 48,18 µg/mL. Dari penelitian tersebut dapat disimpulkan bahwa senyawa analog kalkon (E)-3-(4-metoksifenil)-1-fenilprop-2-en-1-on dapat berpotensi sebagai inhibitor terhadap sel kanker payudara MCF-7
Studi In Silico dan Pengaruh Gugus Metoksi pada Hasil Sintesis Analog Kalkon terhadap Inhibisi Enzim α-Glukosidase Dona, Rahma; Furi, Mustika; Frimayanti, Neni; Zamri, Adel; Nahdiah, Nahdiah
JSFK (Jurnal Sains Farmasi & Klinis) Vol 9 No 1 (2022): J Sains Farm Klin 9(1), April 2022
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.9.1.12-23.2022

Abstract

Kalkon (1,3-diaril-2-propen-1-on) merupakan golongan flavonoid yang memiliki banyak aktivitas salah satunya sebagai antidiabetes. Pada penelitian ini dilakukan sintesis tiga senyawa analog kalkon yaitu 2’-hidroksi-2-metoksi-kalkon (Kalkon1), 2’-hidroksi-3-metoksi-kalkon (Kalkon2) dan 2’-hidroksi-4-metoksi-kalkon (Kalkon3) dan serta dilakukan pengujian karakterisasi nya. Sintesis analog kalkon  dilakukan dengan metode irradiasi microwave menggunakan  katalis KOH, pelarut etanol dan PEG 400. Struktur setiap produk dikarakterisasi melalui spektroskopi UV-Vis, FTIR dan 1H NMR, menunjukkan bahwa ketiga senyawa analog kalkon hasil sintesis memiliki struktur sesuai dengan yang diharapkan, dengan hasil rendemen yaitu 91,53% (Kalkon1), 79,01% (Kalkon 2) dan 77,48% Kalkon 3. Berdasarkan studi in silico dari parameter nilai energi bebas ikatan didapatkan bahwa senyawa Kalkon 3 memiliki nilai energi bebas ikatan terkecil yaitu sebesar -8,8 kcal/mol dibandingkan senyawa Kalkon1 dan Kalkon2 yaitu sebesar -7,5 kcal/mol, -6,8 kcal/mol. Untuk  parameter  kecocokan asam amino dengan kontrol positif (akarbose), hanya senyawa Kalkon1 yang memiliki kecocokan dengan kontrol positif (akarbose) sedangkan untuk parameter ikatan hidrogen didapatkan bahwa semua senyawa uji tidak menunjukkan adanya interaksi berupa ikatan hidrogen antara ligand dan reseptor. Hasil ini menunjukkan senyawa Kalkon1, Kalkon 2 dan Kalkon 3 diperkirakan tidak aktif sebagai inhibitor enzim α-glukosidase.
STUDY OF THE WORKLOAD METHOD, STAFFING NEEDS INDICATOR IN HEALTH FACILITIES: SYSTEMATIC LITERATURE REVIEW Teguh Utama; Seftika Sari; Neni Frimayanti
Cendekia Medika: Jurnal Stikes Al-Ma`arif Baturaja Vol. 10 No. 1 (2025): Cendekia Medika: Jurnal STIKes Al-Ma'arif Baturaja
Publisher : LPPM STIKES Al-Ma'arif Baturaja

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52235/cendekiamedika.v10i1.470

Abstract

Measuring workload plays a crucial role in ensuring optimal performance, employee welfare, and efficient resource allocation. The Workload Indicator Staffing Need (WISN) method has been widely used to assess workload and workforce needs. This systematic literature review aims to evaluate the applicability, reliability, and validity of the WISN method in the context of health services. A systematic search of relevant databases (PubMed & Google Scholar) was conducted to identify studies published between 2014 and 2024, focusing on the application of the WISN method in healthcare. Adopting the PRISMA methodology, 10 articles were selected from an initial 200 articles based on their relevance and methodological quality. This study shows that the WISN method has been effectively applied in various health service contexts, such as hospitals, primary service centers, and clinics. This method offers a structured approach to determining workforce needs based on workload, thus facilitating the efficient allocation of resources. However, a number of studies have highlighted challenges related to data accuracy and the adaptability of the WISN method to various health service conditions. Therefore, the development and integrated approach to the WISN method is needed to balance with various other workload measurement methods to improve reliability and validity.
Co-Authors Abdi Wira Septama Abdi Wira Septama Abdi Wira Septama Adel Zamri Adel Zamri Adel Zamri Adel zamri Adel Zamri Adel Zamri Adel Zamri Adel Zamri Adel Zamri Adel Zamri Adel Zamri agistia, nesa Agustini, Tiara Tri Alifah Nurul Khusnah Amrina Rossada Septilapani Anfasa Mashudi, Fristio Anggraeni, Ica Winanda Anita Lukman Antasya, Vaylia Ariyana Najwa Nabila Suzarman Armon Fernando Bella Parina, Ana Benni Iskandar Bulan Daniel Sialagan Dea Dwi Putri Della Vasmawati Denisya amanda Difa, Faradini Ramsanjami Dwi Endarti Efendi, Apriyani Eka Marisa Putri Elsa Etavianti Elsa Natia Elvi Khairani, Mai Elviyenti, Elviyenti Enda Mora Enda Mora Enda Mora Etavianti, Elsa Fadiyah Yueflen Fatmalia, Anggun Ferdy Firmansya Ferdy Firmansyah Fharisti Kirana Fikri Maulana Fikri Maulana, Fikri Fina Aryani, Fina Fri Murdiya, Fri Furi, Mustika Guntur Guntur Haiyul Fadhli Hamzah, Hasyrul Haryeni Sastra Anggraini Hendra, Rudi Herfindo, Nofal Hery Widijanto Hilwan Y. Teruna Hilwan Yuda Teruna Husnawati Husnawati Ihsan Ikhtiarudin Ikhtiaruddin, Ihsan Iktiarudin, Ihsan Irfan Maulana Iriani, Revy Jasril Jasril , Jasril Jasril Jasril Kiranti Azlin Kolista Sisilawati Kurniawan Putri, Nurafika Lala Azela Larasati Arsad Mazani Febrina Mazaya Putri Anabesi Meiriza Djohari, Meiriza Melzi Octaviani Meri Ernilawati Meridona Mira Febrina, Mira Muharani, Siska Muhtadi, Wildan Khairi Mulia Rizki Musyirna Rahmah Nst Mutiara Putri Amri Mutiara Salsabillah Muttaqin, Fauzan Zein Nadea Zahra Ramadhani Nadila Putri Nahdiah Nahdiah Nahdiah Nahdiah, Nahdiah Nathania , Livia Nelly Oscifiani Nelly Oscifiani Ningsih, Yozi Fiedya Nisa Novrianti Nofriyanti Nova Tantri Silalahi Noval Herfindo Novianty, Riryn Nurul fadillah, Nurul Nurul Susianti Oscifiani, Nelly Panjaitan, Pretty Farida Peng-Wei, Ching Putri Rizki Rahmadani Putri, Monica Rifa Qurnia Pratiwi, Putri R. Rizatita Fitriani Rabiatul Adawiyah Rahayu Rahayu Rahayu Rahayu Rahayu Rahayu Rahayu Utami Rahim, Fatma Rahma Dona Rahmah, Rizka I’zaa Raja adli husin Ramanda safitri Ricardo, Nadira Atiqah Rickha Octavia Rinda Aryudhini Rindiyani Rindiyani Riska Prasetiawati Rivaldo Andy Tanzil Rizda Fitriani Rizki Anugrah Rizky Fadli Putra Rodhia Ulfa Rohim, Muhammad Rosi Ami Sari Rosnita Dewi Rahmawati Rossi Passarella Rudi Hendra Ruska, Shinta Liana Rusnedy, Rahmayati S.Farm., M.Farm., Apt, Sondang Khairani Salsabila alhamdania Balqis Salsabila Zahirah Ananda Salsabila, Aulia Sari, Rinita Seftika Sari Selvi Aulia Wibowo Shafira Melsonia Shelvy Nurhaliza Harianda Silalahi, Nova Tantri Siregar, Lisa Andriyani Sitanggang, Sarah Dianora Siti Nuraida Harahap Siti Rahmah Solihin, Tabah Syaifullah, Mhd Muslim Teguh Utama Thoriq El Haque Tria Harlianti Ulhukmi, Nisa Vella kurnia Wahyuni Veza Azteria viola Afrilizetira, Garnis Wahyuni, Dilla Widya Ari Sandi Winda Yusma Ameliah Wulandari, Zertiks Yasthophi, Arif Yuli Haryani Yum Eryanti Yum Eryanti Yum Eryanti Yuni Fatisa Yuri Amalia, Annisa Zafarani, Welly ⁠ Chindy Retika