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All Journal International Journal of Public Health Science (IJPHS) ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Dasar e-Journal Pustaka Kesehatan Jurnal Kesehatan Masyarakat Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Majalah Geografi Indonesia Jurnal Kesehatan Jurnal Kesehatan Andalas Folia Medica Indonesiana Damianus Journal of Medicine Journal of Agromedicine and Medical Sciences Jurnal Media Gizi Indonesia (MGI) JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) Majalah Kedokteran Sriwijaya Universa Medicina Jurnal Bioteknologi & Biosains Indonesia (JBBI) Journal Of Vocational Health Studies Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Al-sihah: The Public Health Science Journal Jurnal Medik Veteriner SRIWIJAYA JOURNAL OF MEDICINE Journal of Health Sciences JHECDs: Journal of Health Epidemiology and Communicable Diseases JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Berita Kedokteran Masyarakat JEBIMAN: Jurnal Ekonomi, Bisnis, Manajemen dan Akuntansi Jember Medical Journal (JMJ) Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) ASPIRATOR - Journal of Vector-Borne Diseases Studies
Bagus Hermansyah
Departemen Parasitologi, Fakultas Kedokteran Universitas Jember, Jalan Kalimantan 37 Kampus Tegal Boto, Jember, Jawa Timur 68121
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Efek Minuman Keras Oplosan terhadap Perubahan Histopatologi Organ Renal Tikus Wistar Jantan Made Masagung Kawiartha; Rena Normasari; Bagus Hermansyah
Pustaka Kesehatan Vol 6 No 3 (2018)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v6i3.9777

Abstract

Mixed liquor is a liquor mixed with other substances, mainly ethanol and methanol. Mixed liquor can cause kidney destruction. The aim of this study was to investigate the effect of mixed liquor toward kidney's microscopic and macroscopically changes. This study used 24 rats which were divided into 4 groups consist of 1 control group and 3 experimental groups. The first, second, and third experimental groups were given ethanol 1,296ml/2 days; methanol 0,2592ml/2days and aquades 1,4448ml/2 days for 5 days; 11 days and 17 days, respectively. Afterward rats were terminated and the right kidney mass was measured. The kidney tissue was prepared for histological examination and the number of necrotic cell was calculated. According to Kruskal Wallis test, kidney mass was not significantly different (p>α) while total necrotic cells was significantly different (p<α). This study showed that rats induced with mixed liquor for 5 , 11, and 17 days resulted in kidney microscopically change.
Uji Aktivitas Fraksi N-Heksana Ekstrak Metanol Bangle (Zingiber cassumunar Roxb.) sebagai Terapi Komplementer Malaria secara In Vivo (The Activity Test of N-Hexane Fraction of Bangle (Zingiber cassumunar Roxb.) Methanolic Extract as Complementary Thera Sarah Andriani; Bagus Hermansyah; Sugiyanta Sugiyanta
Pustaka Kesehatan Vol 5 No 2 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Malaria is one of endemic disease in Indonesia that caused many deaths. Immune system plays important rules in preventing malaria severity. Bangle has been proven as an immunostimulant and could reduce parasitaemia in malaria infection. This study aimed to determine the activity of n-hexane fraction of bangle methanolic extract as complementary therapy of malaria. This study used 28 mice, divided into one positive control group, one negative control group, and five treatment groups. Bangle stimulation before induction was given to five treatment groups with dose: 0,005625mg/grbw, 0,01125mg/grbw, 0,0225mg/grbw, 0,045mg/grbw, and 0,09mg/grbw for 14 days. Plasmodium berghei induction was given to all groups, and then treatment groups were given ACT and bangle fraction, and positive control group was given ACT without fraction for three days. Parasitaemia was observed everyday, then plasmodium growth inhibition percentation was counted. Bangle fraction stimulation gave lower parasitaemia at the begining and Pearson correlation test showed strong positive correlation between dose of bangle fraction and plasmodium growth inhibition percentation (p<0,01). We can conclude that n-hexane fraction of bangle methanolic extract was active as complementary therapy of malaria (IC50=0,013 mg/grbb). Keywords: malaria, bangle, n-hexane, complementary therapy
Respon Imunogenitas Protein Permukaan 19 kDa Streptococcus pneumoniae (Immunogenicity Response of Streptococcus pneumoniae 19 kDa Surface Protein) Muhammad Dimas Arya Candra Permana; Dini Agustina; Bagus Hermansyah
Pustaka Kesehatan Vol 3 No 1 (2015)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Pneumonia is the main common cause of children death in the world. Microbiological studies found the major causes of pneumonia is Streptococcus pneumoniae. Infection of S.pneumoniae influenced by several virulence factors, one of which is surface protein. The purpose of this study was to determine the immunogenicity of 19 kDa S.pneumoniae surface protein through hemagglutination inhibition and adhesion inhibition test. Adhesion inhibition test used antibodies that is formed from surface protein, to inhibit bacterial adhesion to the enterocytes. Hemagglutination inhibition test also used antibodies that formed from surface protein, to inhibit the agglutination of erythrocytes caused by S.pneumoniae. The results showed that antibodies, which was formed from 19 kDa S.pneumoniae surface protein, were able to inhibit hemagglutination process up to 1X dilution. Adhesion inhibition test showed that the higher antibody dilution, the greater the adhesion index. Pearson correlation analysis of the adhesion test showed that there was a significant correlation between antibody dilution with bacterial adhesion index (R= -0,787; p=0,036). It can be concluded that the 19 kDa surface protein of S.pneumoniae was immunogenic.   Keywords: Streptococcus pneumoniae, surface protein, antibody
Keberhasilan Terapi Konservatif pada Persalinan Preterm Disertai dan Tanpa Disertai Ketuban Pecah Dini di RSD dr. Soebandi, Jember Nurul Furqooniyah; Yonas Hadisubroto; Bagus Hermansyah
Pustaka Kesehatan Vol 7 No 1 (2019): Volume 7 No. 1, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i1.17587

Abstract

Preterm delivery is the greatest cause of neonatal morbidity and mortality. Preterm delivery can be accompanied by premature rupture of membranes. Preterm delivery with and without premature rupture of membranes are managed by conservative therapy to delay birth. Rupture of membranes causes inadequate protection of the fetus. This study aimed to determine the success of conservative therapy in preterm delivery with and without premature rupture of membranes at Regional Hospital (RSD) dr. Soebandi Jember. The study used secondary data from medical records of pregnant women with spontaneous single preterm delivery that has been given conservative treatment from January 2015-January 2017 period. As many as 149 samples were included for the study, which is collected using total sampling technique. This research used cross sectional research design. Chi-Square statistical test results showed a significance of (p = 0.001 <0.05). It can be concluded that there was a significant difference of the success of conservative therapy between the preterm delivery with and without premature rupture of membranes.
Uji Aktivitas Fraksi Diklorometana Ekstrak Metanol Bangle (Zingiber cassumunar Roxb.) sebagai Terapi Komplementer Malaria secara In Vivo (The Activity Test of Dichloromethane Fraction of Bangle (Zingiber cassumunar Roxb.) Methanolic Extract as Complement Edda Rachmadenawanti; Bagus Hermansyah; Yuli Hermansyah
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

World Malaria Report reported that Malaria threats 40% of world population in six regions and ninety seven endemic countries. This study aimed to investigate the activity of dichloromethane fraction of Bangle as a complementary therapy of malaria in vivo. This was true experimental laboratories study using 28 mice of Balb/c, divided into seven groups. Five treatment groups were given five dose of dichloromethane fraction of Bangle methanolic extracts as imunostimulant before malaria infection and during malaria therapy by combining with malaria standard therapy. K(+) group was given malaria standard therapy. K(-) group was not given any therapy after infection. Inhibition percentage of malaria parasite in K(-) was 0 and K(+) was 24,74%. The treatment group of 0,09 mg/grBW had the highest inhibition percentage, as many as 88,19%. It declined by decreasing dose of fraction. The result of pearson correlation showed very strong correlation (r=0,880). The Ic50 value of dichloromethane fraction of Bangle methanolic extract as a complementary therapy was 0,008 mg/grBW. In conclusion, dichloromethane fraction of Bangle methanolic extract had immunostimulant effect and antimalarial activity in vivo.   Key words: bangle, complementary therapy, inhibition percentage, malaria
Hubungan perilaku hidup bersih dan sehat dengan kejadian infestasi Soil–transmitted Helminths pada pekerja perkebunan kopi Sumber Wadung Kabupaten Jember Ahmad Hasbi Al-Muzaky; Bagus Hermansyah; Enny Suswati; Yunita Armiyanti; Yudha Nurdian
JURNAL KEDOKTERAN DAN KESEHATAN Vol 6, No 1 (2019)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (293.379 KB) | DOI: 10.32539/JKK.v6i1.7233

Abstract

Infestasi Soil - Transmitted Helminths (STH) merupakan masalah kesehatan yang masih sering ditemukan di negara beriklim tropis, salah satunya di Indonesia. Hal ini dikarenakan perkembangan STH membutuhkan kondisi lingkungan yang hangat dan lembab, serta  memerlukan media tanah untuk menjadi fase infektif yang disebut soil - transmitted helminth.Kondisi ini dapat ditemukan di lingkungan perkebunan yang sangat menguntungkan bagi perkembangan STH. Hal ini menyebabkan para pekerja perkebunan sangat beresiko terinfestasi oleh STH. Tujuan penelitian ini adalah mengetahui adanya hubungan perilaku hidup bersih dan sehat (PHBS) dengan kejadian infestasi STH pada pekerja perkebunan kopi. Jenis penelitian ini adalah penelitian analisis deskriptif dengan desain cross-sectional yang dilaksanakan pada bulan Desember 2018 hingga Januari 2019. Perkebunan yang dipilih adalah Perkebunan Kopi Sumber Wadung di Kabupaten Jember dengan jumlah sampel sebanyak 100 orang responden dan diberikan kuisioer PHBS. Pemeriksaan infestasi STH dilakukan dengan dua metode yaitu flotasi dan sedimentasi. Dari 100 responden, 28 pekerja (28%) terinfestasi oleh STH. Kemudian dilakukan uji analisis chi-square antara PHBS dengan kejadian infestasi STH dan didapatkan adanya hubungan antara PHBS dengan kejadian infestasi STH pada pekerja (<0,05).
THE RELATION OF PERSONAL HYGIENE WITH THE RISK OF OCCURRENCE OF SOIL-TRANSMITTED HELMINTH CO-INFECTION IN TB PATIENTS IN THE WORKING AREA OF THE JENGGAWAH HEALTH CENTER IN JEMBER REGENCY Ellen Ocktavironita; Bagus Hermansyah; Angga Mardro Raharjo; Diana Chusna Mufida; Dini Agustina; Muhammad Ali Shodikin
Majalah Kedokteran Sriwijaya Vol 52, No 2 (2020): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v52i2.11977

Abstract

Tuberculosis (TB) and soil-transmitted helminth (STH) infections are infectious diseases with a high prevalence in Indonesia. STH co-infection in TB patients can worsen the prognosis of TB disease due to the dysregulation of the immune response. The high prevalence of STH infections in Indonesia is caused by environmental factors such as poor personal hygiene habits. Jenggawah Subdistrict is an area with a high number of TB cases in Jember Regency and most of the area is in the form of agricultural fields and plantations that have a suitable humidity and temperature for the development of STH. The purpose of this study was to determine the relationship of personal hygiene risk factors with the risk of STH co-infection in TB patients in the work area of the Jenggawah Health Center in Jember Regency. This study used an observational analytic design with a cross sectional method and was conducted from September to December 2019. The research was conducted at the TB Polyclinic in Jenggawah Health Center in Jember Regency with a total sample of 26 respondents who were given a personal hygiene questionnaire. Stool examination was conducted at the Laboratory of Parasitology FK UNEJ using sedimentation and flotation methods. The results showed the incidence of STH co-infections was 15.3%, good personal hygiene was 57.7%, and bad personal hygiene was 42.3%. Fisher exact test results showed that there was no significant relationship between personal hygiene risk factors and the risk of the occurrence of STH co-infection in TB patients in the working area of the Jenggawah Health Center in Jember Regency (p = 1,000).
Association between Personal Hygiene and Incidence of Soil-Transmitted Helminthiasis among Workers at Widodaren Plantation in Jember Regency Zulaikha Rizqina Rahmawati; Bagus Hermansyah; Erfan Efendi; Yunita Armiyanti; Yudha Nurdian; Wiwien Sugih Utami
Journal of Agromedicine and Medical Sciences Vol 6 No 1 (2020)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v6i1.9593

Abstract

Soil-Transmitted Helmithiasis is an infection caused by intestinal nematode worms which in the process of transmission requires soil as media to fullfil its life cycle from non-infective forms to infective forms. The number of infections is influenced by personal hygiene. Personal hygiene consists of the habit of washing hands, cutting nails, eating, defecating and ownership of latrines, and the use of personal protective equipment. This study used a cross sectional research design conducted at Widodaren Plantation with 68 people of samples. Stool examination was determined by kato-katz method, sedimentation, and floatation to detect the presence of Soil-Transmitted Helminth (STH) eggs, while personal hygiene was assessed using questionnaires. Questionnaire and stool examination datas were processed using SPSS data analysis with chi-square method. The results of this study found 26 respondents who were positive for soil-trasmitted helminthiasis infection. The most frequent worm species obtained in this study were Ascaris lumbricoides (57.7%), followed by multiple infections between Hookworm and A. lumbricoides (21.3%), and Hookworm (19.2%). In the chi-square analysis the results were significant between personal hygiene and soil-transmitted helminthiasis with p value of 0,000 (p <0.05). So, it can be concluded that a bad personal hygiene factor has a significant relationship to the incidence of Soil-Transmitted Helminthiasis at Widodaren Plantation. Keywords: Personal hygiene, STH, plantation
Combination Effect of Methanol Extract of Hibiscus rosasinensis L. Leaf and Ciprofloxacin against Shigella dysentriae In Vitro Billy Jusup Kurniawan; Muhammad Ali Shodikin; Bagus Hermansyah
Journal of Agromedicine and Medical Sciences Vol 4 No 2 (2018)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v4i2.6541

Abstract

One of way to preventing bacterial resistance is a combination of natural plant products with antibiotics. Hibiscus rosasinensis leaf proved to have antibacterial activity against Shigella dysentriae. Ciprofloxacin is the first-choice antibiotic to treat Shigella dysentriae infection. The purpose of this study was to determine the effect of methanol extract of Hibiscus rosasinensis leaves and ciprofloxacin against S. dysentriae bacteria in vitro. The type of this study was quasi experimental design with posttest only control group design using nine treatment groups (with concentration variation of 0.5 μg / mL, 1 μg / mL, 2 μg / mL, 4 μg / mL, 8 μg / mL, 16 μg / mL, 32 μg / mL, 64 μg / mL, and 128 μg / mL with 5 μg / 5 μL ciprofloxacin) and one control group (only 5 μg / 5 μL ciprofloxacin). The method used was agar well diffusion. The data was the diameter of inhibition zone around the well. The results showed that the variant of hibiscus leaf concentration could inhibit the growth of Shigella dysentriae but formed smaller inhibition zone diameter than ciprofloxacin alone. Keywords: combination, hibiscus rosasinensis leaf, ciprofloxacin, Shigella dysentriae
Relationship of Cholinesterase Activity with Blood Glucose Levels Due to Pesticide Exposure to Farmers in Mlokorejo Village Muhammad Ryznar Faisal Nur Luqmani; Kristianningrum Dian Sofiana; Bagus Hermansyah
Journal of Agromedicine and Medical Sciences Vol 7 No 1 (2021)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v7i1.20576

Abstract

Increase in blood glucose levels can be caused by the long-term use of pesticides by farmers. This study aims to determine whether there is a correlation between the activity of cholinesterase as an indicator of exposure to pesticides and blood glucose of farmers in Mlokorejo Village, Jember Regency. The research method is observational-analytic with a cross-sectional study design. Data in the form of general characteristics of the sample were obtained through interviews, while the data of the activity of cholinesterase and blood glucose levels of farmers were obtained at the Biochemical Laboratory of the Faculty of Medicine, Jember University. The sample size of this study is 30 samples. All of the samples are having an increased activity of cholinesterase. Most of the samples are having normal blood glucose levels. Based on the results of statistical analysis using the Spearman correlation test (a= 0.05), it was concluded that there was no significant correlation between the two variables (p = 0,191). Keywords: blood glucose, cholinesterase, pesticides
Co-Authors Achmad Maududie Achmad Nazalal Furqon Adilah Julinar Irianti Afifatun Hasanah Agustina Tri Endharti Ahmad Hasbi Al-Muzaky Alfianti, Nita Angga Mardro Raharjo Ardyansyah, Rizky Robeth Arifin, Mochammad Samsul Asis Fitriana Ayundasari, Asti Azham Purwandhono Billy Jusup Kurniawan Brillian Adexa Yudinda Burhan, Niniek Cholis Abrori, Cholis Cicih Komariyah Desi Dwi Cahyani Diana Chusna Mufida Diana Chusna Mufida Dicky Setiawan Didi Candradikusuma Didi Candradikusuma Dina Helianti Dinda Ayu Wanodya Supriatiningsih Dini Agustina Drajad, Rahadinda Mutia Dhamar Dwita Aryadina Dwita Aryadina Rachmawati Dwita Sakuntala Edda Rachmadenawanti El Milla, Kardiana Izza Ellen Ocktavironita Elvia Rahmi Marga Putri Enny Suswanti Enny Suswati ENNY SUSWATI Epafroditus Sanjaya Adiguna Erfan Efendi Erma Sulistyaningsih Erma Sulistyaningsih Febrianti, Zahrah Fitri, Nadya Eka Ghaiska Najma Amnur Habib Mustofa Habibi, Ali Hammam Arif Shabri Hanu Neda Septian Heni Fatmawati Hidayat Sujuti Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Indra Samudra Rahmat Irawan Fajar Kusuma Ivan Iqbal Baidowi Jauhani, M. Afiful Jauhar Firdaus Josef Sem Berth Tuda Kesy Sasta Handani Kristianningrum Dian Sofiana Kusiyanto Taslim, Fitranda Lailatis Shofia Laily Nurhayati Laksmi Indreswari Laksmi Indreswari Leersia Yusi Ratnawati Loeki Enggar Fitri M Ali Shodikin M. Ali Shodikin M.S. Irham Rozaq Made Masagung Kawiartha Muhammad Afiful Jauhani Muhammad Alif Taryafi Muhammad Dimas Arya Candra Permana Muhammad Ryznar Faisal Nur Luqmani Nexia Nevarachell Onny Amirsyah Nidya Husna Kholidah Niniek Burhan Nita Alfianti Nugraha, Bima Setia Sandya Nurmaida, Eny Nurul Furqooniyah Pangestu, Ahmad Yudho Hadi Pralampita, Pulong Wijang Primadana, Aditya Putra, Muhamad Dwi Eka Qintar Layallia Faza Rahardjo, Angga Mardro Rahmadhan, Adiz Dwiputra Raissa Puan Andrina Ramadhani, Rafindra Rena Normasari Rezza Putri Mahartika Risyanto, Chusnul Aulia Arisny Putri Sa'bani, Begawan Sakinah, Elly N Salsabila, Yuna Annisa Salsabilla, Safira Putri Nur Samsul Arifin Saputra, Antonius Dwi Sarah Andriani Selly Silfana Liensa septa surya wahyudi, septa surya Shodikin, M. Ali Shofia, Lailatis Siti Zulaikha Sri Rahmanita Sugiyanta Sugiyanta Supangat Supangat Syamsuddin, Alif Fazduani Tiara Ajeng Dewita Tristianti, Farmitalia Nisa Tuda, Josef Sem Berth Tutiana Bayati Umar Zein Wiwien Sugih Utami Wiwin Sugih Utami Yoga Setyo Yonas Hadisubroto Yudha Nurdian Yuli Hermansyah Yuli Hermansyah Yuli Rahmantia, Vania Yuna Annisa Salsabila Yunita Armianti Yunita Armiyanti Zahrah Febianti Zulaikha Rizqina Rahmawati