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All Journal International Journal of Public Health Science (IJPHS) ACTA VETERINARIA INDONESIANA Jurnal Sain Veteriner Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Dasar e-Journal Pustaka Kesehatan Jurnal Kesehatan Masyarakat Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Majalah Geografi Indonesia Jurnal Kesehatan Jurnal Kesehatan Andalas Folia Medica Indonesiana Damianus Journal of Medicine Journal of Agromedicine and Medical Sciences Jurnal Media Gizi Indonesia (MGI) JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) Majalah Kedokteran Sriwijaya Universa Medicina Jurnal Bioteknologi & Biosains Indonesia (JBBI) Journal Of Vocational Health Studies Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Al-sihah: The Public Health Science Journal Jurnal Medik Veteriner SRIWIJAYA JOURNAL OF MEDICINE Journal of Health Sciences JHECDs: Journal of Health Epidemiology and Communicable Diseases JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Berita Kedokteran Masyarakat JEBIMAN: Jurnal Ekonomi, Bisnis, Manajemen dan Akuntansi Jember Medical Journal (JMJ) Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) ASPIRATOR - Journal of Vector-Borne Diseases Studies
Bagus Hermansyah
Departemen Parasitologi, Fakultas Kedokteran Universitas Jember, Jalan Kalimantan 37 Kampus Tegal Boto, Jember, Jawa Timur 68121
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Hubungan Pengetahuan Keamanan Pangan dengan Higiene Penjual dan Kontaminasi Salmonella spp Pada Lalapan Mentah di Kecamatan Patrang Adilah Julinar Irianti; Diana Chusna Mufida; Muhammad Ali Shodikin; Yudha Nurdian; Bagus Hermansyah; Angga Mardro Raharjo
Jurnal Kesehatan Lingkungan Indonesia Vol 21, No 2 (2022): Juni 2022
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.21.2.180-187

Abstract

Latar belakang: Berdasarkan data Wilayah Kerja Puskesmas Patrang didapatkan sebanyak 2964 kasus diare pada tahun 2020 di Kabupaten Jember. Diare dapat terjadi akibat infeksi bakteri Salmonella spp. yang menular secara oral fecal. Bakteri Salmonella spp seringkali mencemari bahan pangan terutama sayuran. Sementara itu, masyarakat Indonesia sering mengonsumsi sayuran mentah yang disebut dengan lalapan mentah. Kontaminasi bakteri pada lalapan mentah dapat disebabkan oleh kondisi higiene penjual yang kurang baik yang dipengaruhi oleh beberapa faktor, seperti pengetahuan keamanan pangan penjual. Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan keamanan pangan dengan higiene penjual dan kontaminan Salmonella spp pada lalapan mentah di Kecamatan Patrang.Metode: Penelitian ini menggunakan metode observasional analitik dengan desain penelitian cross sectional, dan data dianalisis menggunakan uji Spearman Rank. Sampel ditentukan dengan teknik simple random sampling dengan jumlah sampel 30 penjual.Hasil: Hasil penelitian menemukan bahwa 83,3% penjual memiliki pengetahuan keamanan pangan yang baik, 46,7% penjual memiliki higiene personal yang cukup, dan 80% lalapan mentah terkontaminasi Salmonella spp. Pada uji analisis Spearman Rank tidak didapatkan hasil yang signifikan antara pengetahuan keamanan pangan dengan higiene penjual (0,721>0,05) dan tidak ada hasil yang signifikan antara pengetahuan keamanan pangan dengan Salmonella spp (0,235>0,05).Simpulan: Dapat disimpulkan bahwa tidak ada hubungan pengetahuan keamanan pangan dengan higiene penjual dan Salmonella spp pada lalapan mentah di Kecamatan Patrang. ABSTRACT Title: Relation of Food Safety Knowledge, Seller Hygiene, and Salmonella spp on Raw Lalapan in Patrang DistrictBackground: Based on data from the Patrang Health Center Work Area, there were 2964 cases of diarrhea in 2020 in Jember Regency. Diarrhea can occur due to infection with Salmonella spp. which is transmitted oral fecal. Salmonella spp can contaminate food especially vegetables. Meanwhile, Indonesian people often consume vegetables salad called raw lalapan. Raw lalapan contamination can caused by seller poor hygiene that influenced by several factors, such as their food safety knowledge. This study aims to determine the relation of food safety knowledge with seller hygiene and Salmonella spp contaminants on raw lalapan in Patrang District.Method: This study used an analytical observational method with a cross sectional study design, and the data were analyzed using Spearman Rank test. The sample was determined by a simple random sampling technique with a sample of 30 sellers.Result:  The study found that 83.3% seller had good food safety knowledge, 46.7% seller had sufficient personal hygiene, and 80% of raw lalapan  were contaminated with Salmonella spp. In the Spearman Rank analysis test, there were no significant results between food safety knowledge and seller hygiene (0.721>0.05) and no significant results between food safety knowledge and Salmonella spp contaminants (0.235>0 ,05).Conclusion: So, it can be concluded that there was no relation of food safety knowledge with seller hygiene and Salmonella spp contaminants in raw vegetables in Patrang District.
The Correlation between Personal Hygiene of Greengrocer and Coliform Bacteria Contamination in Lettuce in Jember Traditional Markets Qintar Layallia Faza; Diana Chusna Mufida; Muhammad Ali Shodikin; Bagus Hermansyah; Elvia Rahmi Marga Putri
Journal of Agromedicine and Medical Sciences Vol 8 No 2 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i2.30237

Abstract

Lettuce is a vegetable that is usually consumed in raw condition or unprocessed by people. Unprocessed vegetables can cause food-borne diseases. Lettuce that is not processed and being consumed directly can cause contamination by Coliform bacteria. The purpose of this study is to know the correlation between Greengrocer’s personal hygiene and Coliform bacteria contamination in lettuce in Jembertraditional markets. This research used a descriptive observational design with the cross-sectional approach. It took place in eight traditional markets in Jember Regency and Microbiology Laboratory, Faculty of Medicine, University of Jember. The samples used were 41 lettuces purchased from 41 traditional market sellers. The microbiological examination was performed in the laboratory using the most probable number method. The results showed that lettuce sellers had bad personal hygiene (92,7%) and the data from the most probable number test found 97,6% contaminated by Coliform bacteria. The bivariate analysis was used to know the relationship between personal hygiene vegetable seller and contamination Coliform bacteria in lettuce. Thep-value was 0,072, which means there was no relationship between personal hygiene vegetable seller and contamination Coliform bacteria in lettuce. Keywords: lettuce, Coliform, contamination, personal hygiene
Development of standardized herbal therapy of bangle extract (Zingiber Cassumunar Roxb.) on the expression of Icam - 1 for complementary therapy to prevent complications in Malaria Wiwien Sugih Utami; Heni Fatmawati; Bagus Hermansyah
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 8, No 3, (2017)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol8.Iss3.art8

Abstract

Background : Malaria is still a major problem, both in international and national scale. Erythrocytes containing Plasmodium sp. will stimulate the release of Th1 (T helper-1) and release monocytes and macrophages to perform phagocytosis and produce tumor necrosis factor-alpha (TNF-α). The release of iNOS and free radicals would increase the expression of adhesion molecules such as ICAM-1, VCAM-1, CD36, and P-selectin. Research shows that IL- 10 can inhibit the production of TNF - α and IL - 1. TNF-α and ICAM - 1 play a role in the occurrence of cerebral malaria. Bangle (Zingiber cassumunar Roxb.) has a lot of potentials to be utilized as a complementary therapy to prevent the complications of malaria. Objective : This study aims to find the ability of Bangle (Zingiber cassumunar Roxb.) extract as an immunostimulant which would be used as a complementary therapy for standard malaria treatment. Methods : A number of 25 mice Balb/C males were divided into 5 groups, stimulated with methanol fractions of Bangle extract for 14 consecutive days before infected with Plasmodium berghei. All groups were examined for parasite daily, until day 7 post-positive malaria, referring to Artemisinindose regimen administered orally 0.04 mg/g bw/day for 7 days. Results : This study proves that the administration of Artemisinin combined with methanol fraction of Bangle extract provides better results to inhibit ICAM-1 gene expression in malaria-infected mice compared to single-therapy Artemisinin or methanol fraction of bangle extract. Conclusion : The combination of artemisinin and methanol fraction of Bangle extract can inhibit ICAM-1 gene expression in malaria-infected mice better compared to without the combination.
Hubungan antara Higiene Perorangan dan Kejadian Koinfeksi Cacingan pada Penderita Tuberkulosis Lailatis Shofia; Bagus Hermansyah; Enny Suswati; Dini Agustina; Diana Chusna Mufida; Muhammad Ali Shodikin
Sriwijaya Journal of Medicine Vol. 4 No. 1 (2021): Vol 4, No 1, 2021
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v4i1.98

Abstract

Tuberkulosis (TB) dan cacingan merupakan penyakit infeksi dengan jumlah penderita yang banyak di Indonesia. Tingginya prevalensi cacingan di Indonesia memungkinkan terjadinya koinfeksi STH pada pasien TB paru yang menyebabkan imunitas anti M. tuberculosis menurun sehingga respon terhadap pengobatan tuberkulosis menjadi tidak maksimal. Cacingan salah satunya dipengaruhi oleh higiene perorangan. Tujuan penelitian ini adalah untuk menganalisis hubungan antara higiene perorangan dan kejadian koinfeksi cacingan pada penderita TB di Kecamatan Tempurejo Kabupaten Jember. Jenis penelitian ini adalah penelitian observasional dengan desain analitik cross sectional. Populasi yang digunakan adalah pasien TB di Kecamatan Tempurejo dalam periode waktu September – Oktober 2019. Data yang digunakan dalam penelitian ini adalah data primer berupa hasil wawancara dan hasil pemeriksaan feses. Pemeriksaan feses dilakukan menggunakan metode sedimentasi dan floatasi. Analisis data dilakukan menggunakan uji Fisher. Hasil penelitian ini menunjukkan bahwa kejadian koinfeksi cacingan pada pasien TB di Kecamatan Tempurejo Kabupaten Jember sebesar 9,67% dan disebabkan oleh dua spesies STH yaitu A. lumbricoides (66,7%) dan Hookworm (33,3%). Higiene perorangan responden terdiri atas higiene baik (64,5%) dan higiene buruk (35,5%), dimana 66,7% kejadian koinfeksi cacingan terjadi pada responden dengan higiene perorangan buruk. Hasil uji Fisher menunjukkan bahwa tidak ada hubungan yang signifikan antara higiene perorangan dengan kejadian koinfeksi cacingan pada pasien TB di Kecamatan Tempurejo Kabupaten Jember (p-value sebesar 0,281).
Hygiene Related Risk Factors for Giardia Infection in Sukowono District, Jember, Indonesia Selly Silfana Liensa; Wiwien Sugih Utami; Pulong Wijang Pralampita; Bagus Hermansyah
Journal of Agromedicine and Medical Sciences Vol 8 No 3 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i3.32125

Abstract

Giardia spp. is a common cause of diarrhoeal disease in humans and is also known as a zoonotic agent in humans and animals. There are three risk factors of zoonotic Giardia, the first is individual characteristics, the second is hygiene, and the last is environmental. This study aimed to analyze the hygiene related risk factors for Giardia infection in Sukowono District, Jember. The research design was a cross-sectional study with 52 subjects from Sukowono District, Jember. The study was carried out from December 2020 to April 2021. The sampling method used purposive sampling is a non-probability sample and chi-square test for data analysis. Data was analyzed using SPSS statistics programme. P value < 0,05 was considered statistically significant.The result of microscopic examination of 52 fecal samples found 1.9% of the subjects were infected with Giardia spp. There was no association between hygiene behavior factors with Giardia spp. in Sukowono District, Jember (p>0.05). Data suggest that risk factors may not contribute to Giardia spp. infection. Based on these findings, need to do further research about hygiene related risk factors for Giardia spp. infection in Jember especially Sukowono District. Keywords: Hygiene factor, Giardia infection, zoonosis
Sensitivity and Specificity of Nested PCR for Diagnosing Malaria: Cases in Several Areas of Indonesia Samsul Arifin; Loeki Enggar Fitri; Hidayat Sujuti; Bagus Hermansyah; Agustina Tri Endharti; Niniek Burhan; Didi Candradikusuma; Erma Sulistyaningsih; Josef Sem Berth Tuda; Umar Zein
Journal of Tropical Life Science Vol. 8 No. 2 (2018)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.08.02.11

Abstract

Indonesia is still included in high endemic area of malaria infection. Early detection as well as appropriate and quick treatment is needed to be able to prevent and treat malaria in Indonesia. Laboratory examination using a microscopic method is still used as the gold standard to diagnose malaria cases. However, the morphology similarity of some Plasmodium species and the number of parasites that can be seen under microscopy causes malaria diagnosis become difficult if only relying on microscopy diagnostic method. The purpose of this study is to analyze the sensitivity and specificity of nested PCR compared to microscopic examination in diagnosing malaria cases. A cross-sectional study has been carried out in some areas of Indonesia and the microscopic analysis as well as nest PCR was done in Laboratory of Parasitology and Laboratory of Central Biomedical Faculty of Medicine, Universitas Brawijaya, Malang East Java Indonesia. A total of 149 blood samples from patients with clinical symptoms of malaria had been obtained from Sumatra, Sulawesi and East Java during December 2011 to December 2013. From 149 sample, 81.9% samples were diagnosed malaria positive by microscopy examination, whereas the PCR results showed that 90.6% of samples were positive. Nested PCR sensitivity is 97.5%, and microscopy 88.2%. Nested PCR specificity is 40.7%, whereas microscopy 78.5%. PPV and NPV for nested PCR are 88,2% and 78.5% respectively, and for microscopy are 97.5% and 40.7% respectively. Nested PCR has a higher sensitivity than microscopy in diagnosing malaria and is able to detect mixed infection better than microscopic examination. However, it is statistically less specific than microscopy examination.
PHYSICAL WATER QUALITY CONTAMINATED BY SOIL-TRANSMITTED HELMINTHS IN SUMBERSARI DISTRICT, JEMBER REGENCY Laily Nurhayati; Wiwien Sugih Utami; Muhammad Afiful Jauhani; Yunita Armiyanti; Bagus Hermansyah
JURNAL KESEHATAN LINGKUNGAN Vol. 14 No. 4 (2022): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v14i4.2022.282-288

Abstract

Introduction: Soil-Transmitted Helminth (STH) or worm infection is an infection caused by intestinal nematode worm group that can be infectious through the soil medium. One straightforward transmission route is through contaminated water consumption as water is needed daily. This study aims to know the association between quality of physical water and STH contamination in the Sumbersari District, Jember Regency, water sources. Methods: This research is an analytical observational study with a cross-sectional design. Data was obtained from water physical quality inspection and STH contamination in the water laboratory. The 30 samples were taken purposively. Results and Discussion: The results of the data analysis of the association between water temperature and STH contamination showed a p-value of 0.014, the association between watercolor with STH contamination showed a value of 0.566, and the association between odor and TDS of water with STH contamination was not analysed. Statistics analysis results showed a significant association between the quality of water physics and STH contamination in the water sources in Sumbersari District, Jember Regency, with a score of 0.022. Conclusion: The physical quality of water has a positive correlation with STH contamination in water sources in Sumbersari District, Jember Regency.
Kontaminasi Sumber Air oleh Cacing Usus dan Higiene Sanitasi sebagai Faktor Risiko Infeksi Helminthiasis pada Petani Yunita Armiyanti; Brillian Adexa Yudinda; Heni Fatmawati; Bagus Hermansyah; Wiwien Sugih Utami
Jurnal Kesehatan Lingkungan Indonesia Vol 22, No 1 (2023): Februari 2023
Publisher : Master Program of Environmental Health, Faculty of Public Health, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkli.22.1.60-68

Abstract

Latar belakang: Kabupaten Jember khususnya Kecamatan Jenggawah merupakan wilayah agraris dengan pekerjaan utama sebagai petani dan hampir separuh penduduknya tidak mempunyai fasilitas jamban untuk buang air besar. Kebiasaan defekasi yang tidak sehat masih banyak dilakukan oleh masyarakat petani, sehingga bisa mencemari sumber air dengan telur dan larva cacing usus yang berakibat terjadinya penularan helminthiasis. Penelitian ini bertujuan untuk mengetahui adanya kontaminasi sumber air (air sumur dan sungai) oleh cacing usus, faktor risiko higiene sanitasi dan hubungannya dengan prevalensi helminthiasis pada petani di Kecamatan Jenggawah, Kabupaten Jember.Metode: Penelitian ini dilakukan di Kecamatan Jenggawah yang sebagian besar masyarakatnya adalah petani. Jumlah petani yang bersedia terlibat dalam penelitian adalah 56, sehingga jumlah sampel feses dan air sumur yang diperoleh juga sebanyak 56. Sampel air sungai juga diambil untuk diperiksa. Sampel feses dan air diperiksa menggunakan metode sedimentasi dan flotasi untuk identifikasi telur dan larva cacing usus. Faktor-faktor risiko higiene dan sanitasi sebagai variabel bebas didapatkan dari kuesioner dan dianalisis dengan univariat, bivariat dan multivariat.Hasil: Karakteristik responden menunjukkan sebagian besar adalah laki-laki (53,51%), berusia 18-60 tahun (75%), berpendidikan rendah (53,57%), dan berpenghasilan rendah (71,43%). Sampel air sumur yang terkontaminasi telur dan larva cacing usus sebesar 22,2%, sedangkan sampel air sungai semuanya terkontaminasi. Prevalensi helminthiasis pada petani adalah 7,1%. Jenis cacing usus yang banyak ditemukan adalah Hookworm. Hasil uji bivariate (chi-square) menunjukkan kontaminasi sumber air oleh cacing usus berhubungan dengan prevalensi helminthiasis (ρ<0,05). Faktor risiko sanitasi yaitu jenis sumber air (air sungai atau air tanah) dan faktor risiko higiene kebiasaan mandi,cuci dan kakus (MCK) di sungai berhubungan dengan prevalensi helminthiasis (ρ<0,05).Simpulan: Sumber air yang terkontaminasi oleh telur dan larva cacing usus dan penggunaannya untuk kegiatan MCK dapat menjadi sumber transmisi infeksi helminthiasis pada masyarakat petani. ABSTRACTTitle: Contamination of Water Sources by Intestinal Worms and Sanitary Hygiene as Risk Factors for Helminths Infection in Farmers.Background: Jember Regency, especially Jenggawah Subdistrict, is an agricultural area with the main occupation as farmers and almost half of the population does not have latrine facilities for defecation. Unhealthy defecation habits are still widely practiced by farming communities, so that they can contaminate water sources with eggs and larvae of intestinal worms which result in helminthiasis transmission. This study aims to determine the contamination of water sources (well and river water) by intestinal worms, sanitation hygiene risk factors and their association with the prevalence of helminthiasis in farmers in Jenggawah District, Jember Regency.Method: This research was conducted in Jenggawah District where most of the people are farmers. The number of farmers who were willing to be involved in the study was 56, so the number of faecal and well water samples obtained was also 56. River water samples were also taken for examination. Stool and water samples were examined using sedimentation and flotation methods to identify eggs and larvae of intestinal worms. Hygiene and sanitation risk factors as independent variables were obtained from the questionnaire and analyzed using univariate, bivariate and multivariate analysis.Result: The characteristics of the respondents showed that most of them were male (53.51%), aged 18-60 years (75%), low educated (53.57%), and low income (71.43%). Well water samples were contaminated with eggs and larvae of intestinal worms by 22.2%, while river water samples were all contaminated. The prevalence of helminthiasis is 7.1%. The most common type of intestinal worm is Hookworm. The results of the chi-square test showed that contamination of water sources by intestinal worms was associated with the prevalence of helminthiasis (ρ<0.05). Sanitation risk factors, namely the kind of water sources (river water or ground water) and hygiene risk factors, i.e bathing, washing and latrine activities (MCK) habits in rivers are associated with the prevalence of helminthiasis (ρ<0.05).Conclusion: Water sources contaminated by eggs and larvae of intestinal worms and the habit of bathing, washing and latrine activities (MCK) in the river can be a source of transmission of helminthiasis infection in farming communities.
Hygiene and Sanitation Factors Affecting Contamination of Soil-Transmitted Helminths in Household Water Sources in Jember, Indonesia Epafroditus Sanjaya Adiguna; Wiwien Sugih Utami; Ika Rahmawati Sutejo; Bagus Hermansyah; Yunita Armiyanti
Althea Medical Journal Vol 9, No 3 (2022)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v9n3.2587

Abstract

Background: Water sources used by households are at risk of contamination by soil-transmitted helminths (STH). Hygiene and sanitation have an essential role in the transmission and contamination of STH. The objective of this study was to analyze whether there was an association between hygiene and sanitation factors with STH contamination in household water sources in Jember Regency, East Java Province, Indonesia.Methods: This cross-sectional analytic study was carried out from December 2020 to March 2021, including 46 samples from 23 respondents in Sukowono District and 23 respondents in Sukorambi District, Jember Regency, selected using a purposive sampling technique. Primary data on hygiene and sanitation risk factors were obtained from questionnaire interviews. The STH contamination in household water sources was examined by sedimentation and flotation methods. Data were analyzed using Fisher Exact test.Results: The identification of STH contamination in household water sources using microscope examination found hookworm species contaminated 8.7% (n=4) of water sources. There was a significant association between the type of human sewage disposal with STH contamination in household water sources (p=0.037). There was no association between hygiene and other sanitation factors with STH contamination in household water sources (p>0.05).Conclusions: Human sewage disposal that goes directly to sewers and rivers can cause contamination of water sources by STH. Therefore, it is important to dispose of human waste in septic tanks that comply with health requirements to prevent the transmission of STH to humans through water sources.
Increased of IL-4 and Ig E Level in Infection Hookworm in Plantation Workers in Jember Bagus Hermansyah; Yunita Armiyanti; Wiwien Sugih Utami
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.37301

Abstract

Hookworm infection is a disease that is included in the neglected tropical disease. Hookworm infection is suffered by many plantation workers who are closely related to the soil in daily life. Immune response in hookworm-infected individuals will experience disorders, especially in eosinophilia, mastocytosis, and IgE stimulation. It is therefore important to know the immune response to hookworm infections in plantation workers. In this study, eosinophilia was calculated on peripheral blood smears and counts of IL-4 and Ig-E levels by ELISA. The results showed an increase in eosinophil levels from blood samples of patients and a significant increase in IL-4 and IgE levels based on the results of statistical analysis. Keywords: hookworm, plantation worker, IL-4, and IgE
Co-Authors Achmad Maududie Achmad Nazalal Furqon Adilah Julinar Irianti Afifatun Hasanah Agustina Tri Endharti Ahmad Hasbi Al-Muzaky Alfianti, Nita Angga Mardro Raharjo Ardyansyah, Rizky Robeth Arifin, Mochammad Samsul Asis Fitriana Ayundasari, Asti Azham Purwandhono Billy Jusup Kurniawan Brillian Adexa Yudinda Burhan, Niniek Cholis Abrori, Cholis Cicih Komariyah Desi Dwi Cahyani Diana Chusna Mufida Diana Chusna Mufida Dicky Setiawan Didi Candradikusuma Didi Candradikusuma Dina Helianti Dinda Ayu Wanodya Supriatiningsih Dini Agustina Drajad, Rahadinda Mutia Dhamar Dwita Aryadina Dwita Aryadina Rachmawati Dwita Sakuntala Edda Rachmadenawanti El Milla, Kardiana Izza Ellen Ocktavironita Elvia Rahmi Marga Putri Enny Suswanti Enny Suswati ENNY SUSWATI Epafroditus Sanjaya Adiguna Erfan Efendi Erma Sulistyaningsih Erma Sulistyaningsih Febrianti, Zahrah Fitri, Nadya Eka Ghaiska Najma Amnur Habib Mustofa Habibi, Ali Hammam Arif Shabri Hanu Neda Septian Heni Fatmawati Hidayat Sujuti Ida Srisurani Wiji Astuti Ika Rahmawati Sutejo Indra Samudra Rahmat Irawan Fajar Kusuma Ivan Iqbal Baidowi Jauhani, M. Afiful Jauhar Firdaus Josef Sem Berth Tuda Kesy Sasta Handani Kristianningrum Dian Sofiana Kusiyanto Taslim, Fitranda Lailatis Shofia Laily Nurhayati Laksmi Indreswari Laksmi Indreswari Leersia Yusi Ratnawati Loeki Enggar Fitri M Ali Shodikin M. Ali Shodikin M.S. Irham Rozaq Made Masagung Kawiartha Muhammad Afiful Jauhani Muhammad Alif Taryafi Muhammad Dimas Arya Candra Permana Muhammad Ryznar Faisal Nur Luqmani Nexia Nevarachell Onny Amirsyah Nidya Husna Kholidah Niniek Burhan Nita Alfianti Nugraha, Bima Setia Sandya Nurmaida, Eny Nurul Furqooniyah Pangestu, Ahmad Yudho Hadi Pralampita, Pulong Wijang Primadana, Aditya Putra, Muhamad Dwi Eka Qintar Layallia Faza Rahardjo, Angga Mardro Rahmadhan, Adiz Dwiputra Raissa Puan Andrina Ramadhani, Rafindra Rena Normasari Rezza Putri Mahartika Risyanto, Chusnul Aulia Arisny Putri Sa'bani, Begawan Sakinah, Elly N Salsabila, Yuna Annisa Salsabilla, Safira Putri Nur Samsul Arifin Saputra, Antonius Dwi Sarah Andriani Selly Silfana Liensa septa surya wahyudi, septa surya Shodikin, M. Ali Shofia, Lailatis Siti Zulaikha Sri Rahmanita Sugiyanta Sugiyanta Supangat Supangat Syamsuddin, Alif Fazduani Tiara Ajeng Dewita Tristianti, Farmitalia Nisa Tuda, Josef Sem Berth Tutiana Bayati Umar Zein Wiwien Sugih Utami Wiwin Sugih Utami Yoga Setyo Yonas Hadisubroto Yudha Nurdian Yuli Hermansyah Yuli Hermansyah Yuli Rahmantia, Vania Yuna Annisa Salsabila Yunita Armianti Yunita Armiyanti Zahrah Febianti Zulaikha Rizqina Rahmawati