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Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di RSUD Sultan Syarif Mohamad Alkadrie Pontianak: Quality of Life on Type 2 Diabetes Mellitus Patients at Sultan Syarif Mohamad Alkadrie Hospital Pontianak Muhammad Akib Yuswar; Shoma Rizkifani; Ghea Egikania Sutanto
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 15 (2022): Proceeding of Mulawarman Pharmaceuticals Conferences (Proc. Mul. Pharm. Conf.)
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/mpc.v15i1.629

Abstract

KAJIAN INTERAKSI OBAT ANTIDEPRESAN DAN ANTIPSIKOTIK PADA PASIEN SKIZOFRENIA DI RUMAH SAKIT JIWA DAERAH SUNGAI BANGKONG PONTIANAK: STUDY OF ANTIDEPRESSANT AND ANTIPSYCHOTIC DRUG INTERACTIONS IN SCHIZOPHRENIC PATIENTS AT THE BANGKONG RIVER MENTAL HOSPITAL PONTIANAK Shoma Rizkifani; Ressi Susanti; Tri Febiani
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.532

Abstract

Interaksi obat yang digunakan pada pasien skizofrenia didominasi oleh kombinasi antara antidepresan dan antipsikotik. Interaksi ini dapat menyebabkan efektivitas pengobatan berkurang. Penelitian ini bertujuan untuk mengetahui pola penggunaan obat antidepresan dan antipsikotik serta mengetahui gambaran potensi interaksi obat di Rumah Sakit Jiwa Daerah (RSJD) Sungai Bangkong Pontianak periode Januari-Desember 2020. Penelitian ini menggunakan desain potong lintang (cross-sectional) dan metode pengambilan sampel dilakukan secara total sampling. Data dianalisis secara deskriptif dan disajikan dalam bentuk uraian dan tabel. Hasil penelitian menunjukkan bahwa penggunaan obat terbanyak adalah sertralin (54,54%) dari golongan SSRI dan risperidon (42,85%) dari golongan antipsikotik atipikal. Interaksi obat yang paling banyak terjadi yakni interaksi farmakodinamik (62,13%) dibandingkan dengan farmakokinetik (37,86%). Tingkat keparahan interaksi yang terjadi dengan kategori moderat (69,79%) lebih besar daripada kategori mayor (30,20%). Penggunaan obat antidepresan sering diresepkan untuk pasien skizofrenia di RSJD Sungai Bangkong Pontianak yaitu sertralin sebanyak 24 kali peresepan, yang dapat mengatasi gejala depresi pada pasien skizofrenia. Sedangkan obat antipsikotik yang lebih bayak diresepkan adalah risperidon sebagai pengatasan gejala positif dan negatif. Potensi interaksi di RSJD Sungai Bangkong Pontianak 100% masih berpotensi mengalami interaksi obat. Jenis interaksi obat yang banyak terjadi berdasarkan mekanismenya yaitu interaksi farmakokinetik metabolisme sebanyak 69 kasus (58,97%), interaksi farmakodinamik sinergisme terjadi sebanyak 48 kasus (41,02%). Interaksi berdasarkan tingkat keparahan yang lebih banyak terjadi adalah interaksi tingkat keparahan moderat sebanyak 21 kasus kejadian.
Hubungan Tingkat Pengetahuan terhadap Perilaku Swamedikasi Maag Selama Pandemi Covid-19 Shinta Misdariani Nur; Shoma Rizkifani; Nera Umilia Purwanti
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18822

Abstract

Many people in the Tumbang Titi area do self-medication, one of which is ulcer disease because it is considered mild and easy to treat without the supervision of health workers. During the COVID-19 pandemic, self-medication became an alternative choice for people in Tumbang Titi District. This study aims to determine the level of knowledge and behavior of self-medication and whether or not there is a relationship between the level of knowledge and behavior of self-medication. This study is an observational study with cross-sectional design. sampling technique used a purposive sampling with considerations based on inclusion and exclusion criteria for 100 community respondents in Tumbang Titi District. Based on the results of the research on the level of knowledge in the community in Tumbang Titi District, the results were in the good category of 29%, 49% good enough and 22% less good. Self-medication behavior was obtained in good category 19%, good enough 57% and not good 24%. The results of the chi-square test of the level of knowledge and behavior of self-medication showed the results showed the value of Sig. of 0.000 (p 0.005). The conclusion of this study is that the level of knowledge has a fairly good category of 49%, self-medication behavior has a good enough category of 57%, there is a relationship between the level of knowledge and self-medication behavior.
Hubungan Kualitas Hidup Dengan Risiko Depresi Pegawai Publik Universitas X Dimasa Pandemi COVID-19 Shoma Rizkifani; Muhammad Akib Yuswar; Eka Kartika Untari; Nia Resseda
Indonesian Journal of Pharmaceutical Education Vol 3, No 1 (2023): Januari-April 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i1.18836

Abstract

COVID-19 pandemic has had a significant negative impact on the sub-dimension of quality of life, a decrease in quality of life is also correlated with levels of depression. This study aimed to determine the relationship between quality of life and the risk of depression in X University public employees during the COVID-19 pandemic. This research is an analytic observational study and uses a cross-sectional analytic approach, the number of samples is 121 respondents who were selected using a purposive sampling technique. Data were obtained from filling out self-data, quality of life questionnaire (EQ-5D-5L), and depression questionnaire (PHQ-9). The analysis used in this research is a univariate analysis and bivariate analysis. Bivariate analysis using Spearman correlation test. The results showed that most respondents were male, aged 45 years. Respondents have a level of quality of life with a good quality of life category of as much as 57% and a poor quality of life level of as much as 43% and respondents have a level of depression with a mild depression category as much as 26.4%, a moderate depression level as much as 5.8% and a severe depression level as much as 2.5%. The relationship between quality of life and the risk of depression was found to be significant with a significance value of 0.000 with sufficient strength in the negative direction. This study concludes that there is a significant negative relationship between quality of life and the risk of depression in X University public employees during the COVID-19 pandemic.
Effect of Drying Method on Levels of Antioxidant Activity, Total Flavonoid Levels, and Total Phenol Levels in Ethanol Extract of Bawang Dayak (Eleutherine americana) Leaves Sri Wahdaningsih; Shoma Rizkifani; Eka Kartika Untari; William Rinaldi
Majalah Obat Tradisional Vol 28, No 1 (2023)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.80085

Abstract

The drying process can affect the content of seconder metabolites such as flavonoids and phenols in plants. The content of flavonoids and phenols plays an important role in the antioxidant activity of a plant. This study aims to determine the effect of drying methods using sunlight and oven on antioxidant activity, total flavonoids, and total phenols. Measurement of antioxidant activity using the DPPH method with vitamin C as a standard, total flavonoid levels using quercetin as a standard, and total phenol using gallic acid as a standard were measured using a UV-Vis spectrophotometer. The results of antioxidant activity (IC50)by sun drying and oven respectively were 123 ppm and 152 ppm, total flavonoid content by sun drying and oven respectively were 22.5% and 20.698%, and total phenol content by sun drying and oven respectively amounted to 37.35% and 36.648%. The conclusion is that the sun-drying method has antioxidant activity, total flavonoids, and total phenol levels which are greater than the oven-drying method.
Pengukuran Kualitas Hidup Penderita Hipertensi Menggunakan Instrumen EQ-5D-5L Abang Raffli; Muhammad Akib Yuswar; Shoma Rizkifani
Journal Syifa Sciences and Clinical Research Vol 5, No 1 (2023): Volume 5 Edisi 1 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i1.18103

Abstract

Hypertension can affect the quality of life. Poor quality of life is caused by complications with comorbid conditions such as heart disease, kidney disease, and diabetes mellitus. Hypertension occurs when a person's blood pressure is above the normal or optimal limit, namely 120 mmHg for systolic and 80 mmHg for diastolic. This study aims to determine the quality of life of patients with hypertension. This research is an observational study with a prospective cross sectional study design. Data were collected by purposive sampling at the x Health Center that met the inclusion criteria using the European Quality of Life 5 Dimensions 5 level (EQ5D5L) Questionnaire instrument. The data is then converted into a single summary index using the index calculator EQ 5D. From the results of the study, there were 68 cases of hypertension that matched the inclusion criteria, based on gender, it was dominated by 70.5% women with ages 55 to 65 years by 82% with the highest index score percentage 1 (29.41%) and the lowest 0.592. (8.82%) Measuring the quality of life of hypertensive patients at the x Health Center using the EQ5D5L instrument is categorized as good if the EQ5D5L index obtained is 0.5.
Evaluasi Kepatuhan Pengobatan Menggunakan Google Form Pasien Pneumonia di Wilayah Kota Pontianak Robby Najini; Shoma Rizkifani; M. Akib Yuswar; Yeni Utari Ningsih; Ade Ferdinan
Journal Syifa Sciences and Clinical Research Vol 5, No 2 (2023): Volume 5 Edisi 2 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i2.21945

Abstract

Pneumonia is an acute infection with the first line of treatment is antibiotics, so it is necessary to study patient adherence in undergoing treatment using the Medication Adherence Rating Scale (MARS) questionnaire through the Google Form. This study aims to determine the percentage of characteristic descriptions including age, gender, and treatment regimen, know the percentage level of patient adherence in undergoing treatment, as well as knowing the significant difference between monotherapy and combination therapy groups on treatment adherence to pneumonia patients under five in Pontianak City. The method used is an observational method with a cross sectional research design that is analytic. The data was collected by filling out the MARS questionnaire through the Google Form and the data were analyzed using the Chi-Square test method. The results showed that patients aged 4 years (56.1%), male patients (73.7%), monotherapy (70.2%), and high adherence (80.7%). The results of the Chi-Square test showed that there was no significant difference between the monotherapy and combination therapy groups on compliance with pneumonia patients, with values (RR = 0.354; 95% CI = 0.125-1.004). The conclusion of this study the use of Google Form as a survey medium is the percentage of pneumonia sufferers is greater in patients aged 4 years, male, the most commonly prescribed therapy regimen is monotherapy, and patient adherence falls into the high adherence category. There was no significant difference between monotherapy and combination therapy groups on compliance with pneumonia patients in Pontianak City.
Analisis Efektivitas Biaya Antihipertensi Amlodipin Tunggal dan Kombinasi pada Pasien Hipertensi dengan Diabetes Melitus Tipe II Rawat Jalan di Rumah Sakit di Kota Pontianak Dwi Wulan Anggraini; Nurmainah Nurmainah; Shoma Rizkifani
Jurnal Pharmascience Vol 10, No 2 (2023): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v10i2.16014

Abstract

Penyakit hipertensi dengan diabetes melitus tipe II berisiko tinggi untuk berkembangnya penyakit kardiovaskular. Penyakit degeneratif ini membutuhkan pengobatan jangka panjang sehingga analisis efektivitas biaya perlu dilakukan untuk membantu dalam pemilihan obat yang efektif secara biaya maupun luaran klinis. Penelitian ini bertujuan untuk menganalisis efektivitas biaya penggunaan antihipertensi amlodipin tunggal dan kombinasi amlodipin-kandesartan melalui perhitungan Average Cost Effectiveness Ratio (ACER) dan Incremental Cost per Unit of Effectiveness Ratio (ICER). Metode penelitian berupa penelitian observasional dengan rancangan penelitian cross-sectional. Data dikumpulkan secara retrospektif dengan menggunakan data rekam medis dan klaim kuitansi pembayaran pasien hipertensi dengan diabetes melitus tipe II rawat jalan di rumah sakit di Kota Pontianak pada Januari hingga Desember 2021. Subyek penelitian ini sebanyak 34 subyek yang memenuhi kriteria inklusi dan eksklusi. Hasil penelitian menunjukkan karakteristik terbanyak terdapat pada usia ≥60 tahun (58,82%), jenis kelamin perempuan (55,88%), menggunakan antihipertensi amlodipin tunggal (61,76%), dan tekanan darah di hipertensi stage 1 (64,71%). Amlodipin tunggal memiliki efektivitas terapi lebih tinggi 28,57% dibandingkan kombinasi amlodipin-kandesartan (15,38%). Hasil nilai ACER amlodipin tunggal sebesar Rp90.155,93, sedangkan pada kombinasi amlodipin-kandesartan sebesar Rp358.932,05 serta nilai ICER yang sebesar (-)Rp223.246,40. Berdasarkan hasil penelitian ini, disimpulkan antihipertensi yang memiliki biaya lebih efektif adalah amlodipin tunggal dibandingkan kombinasi amlodipin-kandesartan. Kata Kunci: Amlodipin, Amlodipin-Kandesartan, Diabetes Melitus Tipe II, Efektivitas Biaya, Hipertensi  Hypertension with diabetes mellitus type II is at high risk for the development of cardiovascular disease. This degenerative disease requires long-term treatment, so it is necessary to carry out a cost-effectiveness analysis in order to assist in the selection of drugs that are cost-effective and clinical outcomes. This study aimed to analyze the cost-effectiveness of using amlodipine monotherapy and the combination of amlodipine-candesartan through Average Cost Effectiveness Ratio (ACER) and Incremental Cost per Unit of Effectiveness Ratio (ICER) calculations. This study method was an observational study with a cross-sectional research design. Data were collected retrospectively using medical records and claim receipts for payment of hypertensive patients with diabetes mellitus type II outpatient in a hospital in Pontianak City from January to December 2021. The subjects of this study were 34 subjects who have the inclusion and exclusion criteria. The results of the statistical study showed that the most common were aged ≥60 years (58.82%), female (55.88%), using the antihypertensive amlodipine monotherapy (61.76%), and blood pressure was in hypertension stage 1 (64.71%). Amlodipine monotherapy has a higher therapeutic effectiveness of 28.57% compared to the amlodipine-candesartan combination (15.38%). The results of the ACER of amlodipine monotherapy was Rp90,155.93, while for the amlodipine-candesartan combination it was Rp358,932.05 and the ICER value obtained was (-)Rp223,246.40. Based on the results of this study, it was concluded that amlodipine monotherapy is more cost-effective than the amlodipine-candesartan combination. 
Pemberdayaan Kader Kesehatan dalam Upaya Pencegahan Stunting pada Anak di Puskesmas Perumnas II Kota Pontianak: Dissemination of Stunting Prevention in Children at the Public Health Center II in Pontianak City Sri Wahdaningsih; Siti Nani Nurbaeti; Shoma Rizkifani; M Rafly Agustriangga; Risa Indriyani
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 5 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i5.4645

Abstract

Stunting is a chronic malnutrition problem characterized by short stature in children. The high prevalence of stunting in the long term in children will impact economic losses for Indonesia. Nowadays, nutritional problems are not only seen as health problems but have become a shared responsibility, and they need attention from all sectors, including educational institutions such as the Faculty of Medicine. The leading cause of stunting is malnutrition for a long time. Community Service Activities (PKM) aim to equip the Perumnas II Health Center cadres with information, education, and skills related to information on stunting prevention. This PKM activity consists of several activities, including designing educational methods, stunting educational media, and administering pretests and posttests. The results show an increase in the understanding of cadres with the indicator that the average pretest score is 55 and the average posttest score is 71.75. In conclusion, there has been an increase in the understanding of the Perumnas II Health Center cadres.
KAJIAN INTERAKSI OBAT ANTIDEPRESAN DAN ANTIPSIKOTIK PADA PASIEN SKIZOFRENIA DI RUMAH SAKIT JIWA DAERAH SUNGAI BANGKONG PONTIANAK: STUDY OF ANTIDEPRESSANT AND ANTIPSYCHOTIC DRUG INTERACTIONS IN SCHIZOPHRENIC PATIENTS AT THE BANGKONG RIVER MENTAL HOSPITAL PONTIANAK Shoma Rizkifani; Ressi Susanti; Tri Febiani
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 1 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i1.532

Abstract

Interaksi obat yang digunakan pada pasien skizofrenia didominasi oleh kombinasi antara antidepresan dan antipsikotik. Interaksi ini dapat menyebabkan efektivitas pengobatan berkurang. Penelitian ini bertujuan untuk mengetahui pola penggunaan obat antidepresan dan antipsikotik serta mengetahui gambaran potensi interaksi obat di Rumah Sakit Jiwa Daerah (RSJD) Sungai Bangkong Pontianak periode Januari-Desember 2020. Penelitian ini menggunakan desain potong lintang (cross-sectional) dan metode pengambilan sampel dilakukan secara total sampling. Data dianalisis secara deskriptif dan disajikan dalam bentuk uraian dan tabel. Hasil penelitian menunjukkan bahwa penggunaan obat terbanyak adalah sertralin (54,54%) dari golongan SSRI dan risperidon (42,85%) dari golongan antipsikotik atipikal. Interaksi obat yang paling banyak terjadi yakni interaksi farmakodinamik (62,13%) dibandingkan dengan farmakokinetik (37,86%). Tingkat keparahan interaksi yang terjadi dengan kategori moderat (69,79%) lebih besar daripada kategori mayor (30,20%). Penggunaan obat antidepresan sering diresepkan untuk pasien skizofrenia di RSJD Sungai Bangkong Pontianak yaitu sertralin sebanyak 24 kali peresepan, yang dapat mengatasi gejala depresi pada pasien skizofrenia. Sedangkan obat antipsikotik yang lebih bayak diresepkan adalah risperidon sebagai pengatasan gejala positif dan negatif. Potensi interaksi di RSJD Sungai Bangkong Pontianak 100% masih berpotensi mengalami interaksi obat. Jenis interaksi obat yang banyak terjadi berdasarkan mekanismenya yaitu interaksi farmakokinetik metabolisme sebanyak 69 kasus (58,97%), interaksi farmakodinamik sinergisme terjadi sebanyak 48 kasus (41,02%). Interaksi berdasarkan tingkat keparahan yang lebih banyak terjadi adalah interaksi tingkat keparahan moderat sebanyak 21 kasus kejadian.
Co-Authors A.A. Ketut Agung Cahyawan W Abang Raffli Ade Ferdinan Agustriangga, Muhammad Rafly Agvina Felicia Esperanza Ajeng, Melia Anas Putri Maria Natasya Panamuan Anindia, Winda Ardini, Citra Bambang WIJIANTO Chang, Samuel Crishanzen Defiga Kasrin Dhenaya Pradina Dwi Wulan Anggraini Eka K. Untari Eka Kartika Untari Eka Kartika Untari Eka Kartika Untari Eka Kartika Untari Elisabeth indah Mulatsih Fahmi, Ayu Aulia Uly Fajar Nugraha Felisitas Feli Filomina Dila Putri Gamayanti, Tasiana Gisela Ghea Egikania Sutanto Hadi Kurniawan Hafrizal Riza Hariyanto IH Husnatika Indriyani, Risa Intan Khairunnisa Khairunnisa, Intan Lestari, Eka Rizki Liza Pratiwi Lusi Ariska Triani M Rafly Agustriangga M. Akib Yuswar Mariani, Luluk Muhammad Akib Yuswar Muhammad Akib Yuswar Muhammad Akib Yuswar Muhammad Akib Yuswar Muhammad Akib Yuswar Mulatsih, Elisabeth indah Najini, Robby Nera Umilia Purwanti Nera Umilia Purwanti, Nera Umilia Nia Resseda ningsih, yetiutari Nurmainah Nurmainah Nurmainah Nurmainah Nurmainah Oi, San Putra, Berlian Rizky Putri, Alifa Rapaella Fadia Tito Putri, Arsalna Daersa Rikalia, Rikalia Risa Indriyani Robby Najini Robiyanto, Robiyanto Ronaldo, Ronaldo Ropica, Meri Ropiqa, Meri Rupiani, Aprias Saputra, Pinsensius Boni Sarah M. Sasfi Shinta Misdariani Nur Shinta Nia Putri Siti Nani Nurbaeti Sri Wahdaningsih Susanti, Ressi Sutanto, Ghea Egikania Tri Febiani Ulfa Sri Mandasari Utari, Eka Kartika Vanie, Vanie William Rinaldi Yeni Utari Ningsih Yulnalia Mariella Delavega Yuswar, Akib Yuswar, Muhammad Akib