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Journal : Nusantara Science and Technology Proceedings

Correlation of Diabetes Mellitus and Cellular Components using Fuzzy K-Partite Wa Ode Rahma Agus Udaya Manarfa; Wisnu Ananta Kusuma; Imas Sukaesih Sitanggang
Nusantara Science and Technology Proceedings 2nd Basic and Applied Science Conference (BASC) 2022
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2022.2509

Abstract

PPI clustering is one of the computational methods to identify proteins that affect type 2 diabetes mellitus. One of the graph-based fuzzy clustering algorithms, namely fuzzy k-partite clustering was built to solve the problem of biological network data that has more than one function and is present in more than one cluster. which may have overlapping cluster members. A previous study analyzed the mechanism of herbal medicine using the fuzzy k-partite graph clustering method, it was found that there are three groups of proteins that have the same role in overcoming type 2 DM. in the form of backbone tissue (GO-protein). The stages in this research are type 2 DM protein data, search for significant MCL clustering proteins, mining of cellular components in the Uniprot web database, adjacency matrix construction, bipartite network formation with Fuzzy k-Partite Clustering and cluster analysis. This shows that the output of using the algorithm is a network that can provide information on biological processes in type 2 DM. If the weight of the relationship between clusters is high, it can be ascertained that the value of the degree of membership in the cluster is low and there are few cluster members. Conversely, if the weight of the relationship between clusters is low, the degree of cluster membership is high and there are many cluster members. In other words, the value of the degree of membership resulting from the application of this algorithm is inversely proportional to the value of the connectivity between clusters.
Co-Authors Abdul Aziz Abdul Rahman Saleh Adrianus, Albert Afifa, Rizky Maulidya Agus Buono agus Nurrohim Agus Sugiyono Ahmad, Tarmizi Aini Fazriani Aisah Rini Susanti Akhmad Faqih Alami, Tegar Ali Djamhuri Annisa Annisa Annisa , Annisa Annisa Annisa Annisa Annisa Annisa Annisa Annisa Annisa Anton Suryatama Arini Aha Pekuwali Arini Pekuwali Arwan Subakti Ary Prabowo Ary Prabowo Auliatifani, Reza Auliya Ilmiawati Auriza Rahmad Akbar Azizah, Norma Nur Azzahra, Syarifah Fathimah Badollahi Mustafa Badrut Tamam Bahrul Ulum Budi Tjahjono Dahrul Syah Diah Handayani Dian Indah Savitri Dian Kartika Utami Essy Harnelly Fadli , Aulia Fahrury Romdendine, Muhammad Farhan Ramadhani , Hilmi Farit Mochamad Afendi Farohaji Kurniawan Fatriani, Rizka Fazriani, Aini Firman Ardiansyah Fithri, Silvy Rahmah Ginoga, Muh Fadhil Al-Haaq Halida Ernita Handayani, Vitri Aprilla Handayani, Vitri Aprilla Hanifah Nuryani Lioe Hardi, Wishnu Hasibuan, Lailan Sahrina Hendra Rahmawan Hendra Rahmawan Hera Dwi Novita Heru Sukoco Hesty, Nurry Widya Imas Sukaesih Sitanggang Indra Astuti Ira Maryati Irfan Wahyudin Irma Herawati Suparto Irman Hermadi Irmanida Batubara Irvan Lewenusa ISKANDAR ZULKARNAEN SIREGAR Isnan Mulia Janti G. Sudjana Jaya Sena Turana Joni Prasetyo Kana Saputra S Kangko, Danang Dwijo Karlisa Priandana Khaydanur Khaydanur Khaydanur, Khaydanur Laela Wulansari Larasati Larasati Lina Herlina Tresnawati Listina Setyarini Lusi Agus Setiani M. Rafi Maggy T. Suhartono Mala Nurilmala Medria Kusuma Dewi Hardhienata Mohamad Rafi Mohamad Rafi Mohamad Rafi Mohammad Romano Diansyah Mohammad Romano Diansyah Muchlishah Rosyadah Muhammad Asyhar Agmalaro Muhammad Subianto Mulyati Mulyati Mushthofa Muttaqin, Muhammad Rafi Nasution, Tegar Alami Nengsih, Nunuk Kurniati Norma Nur Azizah Nunuk Kurniati Nengsih Nur Choiriyati Nurdevi Noviana Ovi Sofia Pramita Andarwati Pranoto, Bono Prihasuti Harsani Priyo Raharjo Pudji Muljono Purnajaya, Akhmad Rezki Purnomo, Tsania Firqin Ramadhanti, Nabila Sekar Ramdan Satra Ratu Mutiara Siregar Refianto Damai Darmawan Refianto Damai Darmawan Resnawati Reza Auliatifani Rif’ati, Lutfah Ronald Marseno Rosy Aldina Rosyadah, Muchlishah Rudi Heryanto SATRIYAS ILYAS Septaningsih, Dewi Anggraini Siti Syahidatul Helma Sony Hartono Wijaya Sri Nurdiati SUHARINI, YUSTINA SRI Sulistyo Basuki Sulistyo Basuki Supriyanto, Arif Syahid Abdullah Syarifah Aini Syukriyansyah Taufik Djatna Toni Afandi Tsania Firqin Purnomo Usman, Muhammad Syafiuddin Wa Ode Rahma Agus Udaya Manarfa Wahjuni, Sri Widya Sari Wijaya, Eko Praja Hamid Wijaya, Prima Trie Wijayanto, Rudi P. Wina Yulianti Wishnu Hardi Wulansari, Laela Yandra Arkeman Yessy Yanitasari Yudhi Trisna Atmajaya yudiartono, yudiartono Yulianah Yulianah Yunita Fauzia Achmad Zulkarnaen, Silvia Alviani