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All Journal Jurnal Kedokteran Brawijaya International Journal of Integrated Health Sciences Majalah Kedokteran Bandung Althea Medical Journal Folia Medica Indonesiana Global Medical and Health Communication JURNAL PENDIDIKAN KEPERAWATAN INDONESIA JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Jurnal Gizi Klinik Indonesia Jurnal Biomedika dan Kesehatan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia

Leonardo Lubis

Department of Anatomy Faculty of Medicine Universitas Padjadjaran

Author-ID : 309091

Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Correlation between Learning Comfort and the Risk of Musculoskeletal Disorder in Anatomy Laboratorium Activity Based on RULA Method Lubis, Leonardo; Putri, Jesslyn Christianningrum; Ardisasmita, Mulya Nurmansyah
International Journal of Integrated Health Sciences Vol 7, No 1 (2019)
Publisher : International Journal of Integrated Health Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v7n1.1566

Objective:Â To describe learning comfort in the anatomy class of the Faculty of Medicine, Universitas Padjadjaran as one of the learning facilities, to assess the risk of musculoskeletal disorders in students, and to observe correlation between learning comfort and the risk of musculoskeletal disorders in students.Â Method:Â A cross sectional research design conducted to the participants that were students from batch 2017 (second year), faculty of Medicine, Universitas Padjadjaran as the population sample. Data were taken using a Likert scale questionnaire (very uncomfortableâ€“very comfortable) about the comfort aspects in the class, meanwhile the risk of musculoskeletal disorders were assessed by using Rapid Upper Limb Assessment (RULA). After data collection, there were 106 respondents with complete data, then the data were processed by using descriptive statistical analyses. The correlation between the two variables was analyzed using the Gamma correlation test.Results: Majority of the students were very comfortable with the aspects of learning comfort (majority scale 5), except in aspects of furniture, work area, room aroma, personal storage area, maintenance and repair. A moderate risk level of musculoskeletal disorders (58.5%) was found in the majority of the students. There was a relative significant relationshipÂ between learning comfort and the risk of musculoskeletal disorders in the aspect of colors (Î³=0.445, p<0.01).Conclusion:Â There is a significant relationship between learning comfort in the aspect of colors and the risk of musculoskeletal disorders. Other aspects do not indicate a significant relationship.Keywords: Learning comfort, risk of musculoskeletal disorders, RULAÂ

Role of Physical and Cognitive Factors in Passing Abilities of Futsal Athletes in Universitas Padjadjaran Lubis, Leonardo; Muhammad, Afan Maulana; Nandina, Oktavia
Majalah Kedokteran Bandung Vol 51, No 2 (2019)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v51n2.1578

Futsal is a variation of soccer, to be played on a smaller field, with the fastest development among other indoor sports. Futsal players need to master several basic playing techniques to be able to play good futsal, one of them is passing. There are 2 factors that affect futsal athlete skills; physical and mental factors, including cognitive factors. This study aimed to determine the contribution of physical and cognitive factors on the ability to execute passing techniques. A cross-sectional analytic study was conducted in October 2018 on 33 participants who were listed as futsal players in the Faculty of Medicine Futsal Unit, Universitas Padjadjaran, and in the amateur futsal club, La Coruna FC. Physical factor data consisting of body muscle mass percentage, leg muscle percentage, total body fat percentage, and legs subcutaneous fat percentage were measured using Body Impedance Analysis tool while the cognitive factors consisting of; attention, short term memory, and spatial ability, were measured using grid concentration test, digit span test, and spatial ability test, respectively. Athleteâ€™s passing ability was measured using 30 second pass and stop test. Data were then analyzed using regression analysis. The results showed that the percentage of leg muscles has the highest significance value for the athleteâ€™s passing ability. (Î²=0.6, p<0.05) while the leg muscles percentage and attention level are shown to be the physical and cognitive factors which play greater roles in the passing ability of futsal athletes.Peran Faktor Fisik dan Kognitif Â terhadap Performa Teknik Dasar Passing Atlet Futsal Universitas PadjadjaranÂ Futsal adalah variasi sepakbola yang dimainkan di lapangan yang lebih kecil. Atlet futsal perlu menguasai beberapa teknik bermain dasar untuk bermain futsal dan salah satunya adalah passing. Ada 2 faktor yang memengaruhi keterampilan atlet futsal, yaitu fisik dan mental yang salah satunya adalah kognitif. Penelitian ini bertujuan mengetahui kontribusi faktor fisik dan kognitif terhadap kemampuan teknik passing. Studi analitik cross-sectional dilakukan terhadap 33 peserta yang terdiri dari atlet futsal Fakultas Kedokteran dan atlet futsal klub amatir, La Coruna FC selama Oktober 2018 di Jatinangor. Data komponen fisik terdiri atas persentase massa otot tubuh, persentase otot tungkai, persentase lemak tubuh total, dan persentase lemak subkutan kaki yang diukur dengan alat analisis impedansi tubuh, sedangkan kognitif terdiri atas konsentrasi, memori jangka pendek, dan kemampuan spasial yang masing-masing diukur dengan uji konsentrasi grid, uji rentang digit, dan uji kemampuan spasial. Kemampuan passing diukur menggunakan tes pass and stop selama 30 detik. Data kemudian diproses dengan analisis regresi. Hasil Analisis regresi menunjukkan persentase otot kaki memiliki nilai signifikansi tertinggi untuk kemampuan passing atlet. (Î²=0,6, p<0,05). Persentase otot tungkai dan tingkat konsentrasi adalah faktor fisik dan kognitif yang memiliki peran lebih besar dalam kemampuan passing atlet futsal Jatinangor.Â

PENGARUH AKUT MUSIK KLASIK TERHADAP KEMAMPUAN SPASIAL Lubis, Leonardo; Fitria, Nita
Majalah Kedokteran Indonesia Vol 69 No 4 (2019): Journal of the Indonesian Medical Association Majalah Kedokteran Indonesia Volum
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.0679/jinma.v69i4.68

Pendahuluan: Musik klasik adalah komposisi musik dengan melodi kompleks yang dapat mengaktivasi area Brodmann 22, 9, 46, 17, 18, dan 19. Area-area tersebut penting pula untuk kemampuan spasial, yaitu fungsi kognitif untuk merancang, menggambarkan, dan membayangkan suatu objek dalam ruang secara tepat. Dalam bidang kedokteran, kemampuan spasial sangat dibutuhkan untuk pembelajaran anatomi, interpretasi radiograf dan prosedur bedah. Tujuan penelitian ini adalah untuk mengetahui pengaruh music klasik terhadap kemampuan spasial. Metode: Penelitian eksperimental dilakukan terhadap subjek,yaitu: 182 orang mahasiswa kedokteran Unpad yang terdiri dari 117 orang perempuan dan 65 orang laki-laki. Subjek dikelompokkan menjadi kelompok yang diperdengarkan musik Mozart Sonata K448 selama 10 menit (perlakuan) dan kelompok yang tidak diperdengarkan apapun dan hanya duduk diam selama 10 menit (kontrol). Setelah perlakuan, subjek mengerjakan tes spasial. Parameter yang diamati adalah rata-rata nilai tes spasial. Hasil dianalisis dengan uji T tidak berpasangan. Hasil: Rerata skor spasial kelompok musik klasik lebih tinggi secara bermakna (p<0,05) dibandingkan kelompok kontrol, baik pada perempuan (33,6379 vs. 31,6949)(nilai p 0,0235) maupun laki-laki (36,8387 vs. 33,9198)(nilai p 0,0125). Kesimpulan: Musik klasik memberikan stimulasi area fungsional otak spesifik sehingga dapat meningkatkan kemampuan spasial secara akut.

Korelasi antara Obesitas Anak dengan Nadi Istirahat, Tekanan Darah, Kadar BDNF, dan Kebugaran Lubis, Leonardo; Fani, Regina Chintya; Rossanti, Rini; Purba, Ambrosius
Jurnal Kedokteran Brawijaya Vol 30, No 4 (2019)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2019.030.04.15

Obesitas pada anak merupakan manifestasi sindroma metabolik yang dapat memengaruhi sistem kardiovaskular seperti nadi dan tekanan darah, yang disebabkan oleh kombinasi antara kurangnya aktivitas fisik dan pola makan yang berlebih. Aktivitas fisik yang kurang, tidak hanya memengaruhi tingkat kebugaran, tetapi dapat pula memengaruhi ekspresi protein Brain-Derived Neurotrophic Factor (BDNF) yang merupakan biomarker untuk fungsi kognitif. Penelitian ini bertujuan untuk mengetahui hubungan obesitas terhadap komponen kardiovaskular, tingkat kebugaran dan BDNF. Penelitian analitik-korelatif dilakukan pada siswa SD dan SMP berusia 9-14 tahun dengan status Indeks Masa Tubuh (IMT) obesitas sesuai grafik pertumbuhan versi Centers for Desease Control and Prevention (CDC). Tes kebugaran fisik dilakukan berdasarkan Asian Committee on the Standardization of Physical Fitness Test (ACSPFT) sedangkan kadar BDNF serum diketahui melalui metode Enzyme link Immunoabsorbent Assay (ELISA). Hasil analisis Pearson menunjukkan korelasi yang signifikan antara IMT dengan nadi istirahat pada anak usia 9-14 tahun yang mengalami obesitas. Korelasi yang signifikan antara IMT dengan tekanan darah, BDNF serum dan tingkat kebugaran belum dapat dibuktikan. Dengan demikian, anak obesitas berusia 9-14 tahun cenderung mengalami penurunan fungsi sistem kardiovaskular meskipun tidak terlihat pengaruhnya terhadap BDNF serum dan tingkat kebugarannya.

Intervention of Hydration Protocol on Strength, Endurance, and Muscle Power Performance Ramadhan, Wahyu Syahrul; Lubis, Leonardo; Oktavia, Nandina; Womsiwor, Daniel; Tarigan, Beltasar
JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA Vol 6, No 2 (2021): Opportunities from The Sport and Health Education to Improve Quality of Life
Publisher : Universitas Pendidikan Indonesia

WaterÂ is a molecule that plays an essential role in the muscle contraction process because muscle is a tissue that mostly contains water (75-80%). Therefore, athletes need to maintain fluid intake to support their physical activities when competing and when training. Nevertheless, in several studies, it was noted that some athletes experienced hypohydration or dehydration, which ultimately impaired muscle performance. Therefore, this study was conducted to determine the hydration protocol intervention on muscle strength, endurance, and power performance. This research is an analytical study with quasi-experimental research methods, namely single-arm pre-post study design using secondary data. Subjects of this study were 69 athletes year 2020 (named consecutively: Muaythai 9, Pencak silat 12, wrestling 10, judo 18, and taekwondo 20 athletes). This research was conducted from December 2019 to January 2020. In the beginning, all athletes were tested for muscle strength using a leg dynamometer, then muscle endurance tests using push-up and sit-up tests, and muscle power tests using the triple hop test of the right and left legs. After the first test, all athletes were educated about the hydration protocol. The hydration protocol was determined based on each athlete's sweat rate (ISR) and the training characteristics of each sports division. Then, all athletes underwent the training for two months. After that, the same tests were performed. The result showed that hydration protocol influenced the performance of muscle strength, endurance, and power. Therefore, the hydration protocol is influential in maintaining a good hydration status in athletes so that the athlete does not experience hypohydration which will later impair the athlete's muscle performance. Therefore, it is crucial to apply hydration protocols individually according to the training program (volume of training), not only in martial arts sports but in all sports.

Impact of Propolis Administration on Osteocrin Expression and Osteoblast-to-Osteoclast Ratio in the Femurs of Rats Fed a High-fat Diet Widiyanti, Alvira; Tarawan, Vita Murniati; Lubis, Leonardo
Global Medical & Health Communication (GMHC) Vol 12, No 2 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i2.13833

A high-fat diet (HFD) is associated with bone inflammatory processes that can affect bone remodeling balance. Osteocrin produced by periosteal osteoblasts correlates with osteoblast activity, is expressed on osteoblast-derived cells, and is localized in osteoblasts and young osteocytes. Propolis is an antioxidant and anti-inflammatory in bone remodeling by inhibiting proinflammatory factors NF-κB and COX-2, reducing inflammatory suppression of cytokines responsible for osteoclast differentiation and osteoblast apoptosis. The flavonoid content increases the production of nitric oxide and osteoprotegerin, which enhances osteoblastogenesis. This study determined the effect of propolis administration on bone formation and resorption in bone previously damaged by an HFD. This research was conducted in the Animal Laboratory of Postgraduate Building Dipati Ukur and Genetics and Molecular Laboratory Eycman Building, Faculty of Medicine, Universitas Padjadjaran. The research time was from January 2023–May 2024. Male Wistar rats were divided into four groups: normal chow diet (NCD), NCD with propolis administration, HFD, and HFD with propolis administration. The 12-week-old rats were given an HFD for 12 weeks and then treated with propolis at a 300 mg/kgBW dose for nine weeks. The administration of propolis increased the ratio of osteoblasts-osteoclast cells in the femur of the HFD rats but did not affect periosteal osteocrin expression.

CORRELATION BETWEEN LDL, HDL, AND TRIGLYCERIDE CONDITIONS WITH BODY FAT PERCENTAGE OF UNIVERSITAS PADJADJARAN PROFESSORS Saputra, Yosi Wailan; Miftahurachman, Miftahurachman; Lubis, Leonardo
Folia Medica Indonesiana Vol. 53 No. 3 (2017): September 2017
Publisher : Universitas Airlangga

Elderly is a problem that may disrupt the balance of various molecules in the body, especially fat molecules, which may result in the emergence of various diseases so that blood fat and adipose level examinations need to be done regularly and periodically as an effort of early detection. This study aimed to find correlation between Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), and triglyceride with body fat percentage among professors in Universitas Padjadjaran (Unpad) who were mostly in elderly age. This study was a linear regression analytical study conducted on 52 Unpad professors (â™‚ 75%, â™€ 25%) based on data of LDL, HDL, and triglyceride levels obtained through laboratory examination, as well as body fat percentage data by using Bio Impedance Analysis (BIA). The correlation between low density lipoprotein (LDL), High Density Lipoprotein (HDL), and triglyceride with body fat percentage in male professors group was R2=0.072; P>0.05 and in female was R2=0.028; P>0.05. As a conclusion, there was no correlation between Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), and triglyceride with body fat percentage in Unpad professors.

Correlation of Various Levels of Body Mass Index to Vascular Endothelial Growth Factor-A Permana, Noah Jefferson; Lesmana, Ronny; Setiawan, Setiawan; Lubis, Leonardo; Rosdianto, Aziiz Mardanarian; Rejeki, Purwo Sri
Althea Medical Journal Vol 12, No 3 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n3.4296

Background: Obesity, reflected by high body mass index (BMI) value, has become a global health concern. Both obesity and vascular endothelial growth factor-A (VEGF-A) are major risk factors for cardiometabolic diseases. Although many studies have shown that obesity induces angiogenesis through increased VEGF-A, there remains a gap regarding the correlation between BMI categories and VEGF-A levels. This study aimed to analyze the correlation between various level of BMI and VEGF-A concentrations.Methods: This cross-sectional in vivo study analyzed blood samples from 90 adults enrolled in the Universitas Padjadjaran Wellness Program ( December 2022–June 2023) selected using simple random sampling.VEGF-A concentrations were measured using multiplex ELISA assays. Data normality was assessed using the Kolmogorov-Smirnov test. Differences between BMI groups were analyze with ANOVA, and correlations were evaluated using Pearson’s test. Results: Of the 90 samples, 62 were included, and were grouped as normal weight (29%), overweight (32.2%), obesity class I (30.6%), obesity class II (6.4%), and obesity class III (1.6%). Mean VEGF-A concentrations showed an increasing trend with higher BMI, though differences between groups were not statistically significant (p=0.482). A weak positive correlation was observed between BMI and VEGF-A levels (r=0.267; p=0.036).Conclusion: Higher BMI is associated with higher VEGF-A, indicating obesity-induced inflammation and angiogenic activity. These findings highlight the importance of weight control through balanced diet and physical activity to mitigate long-term risks of cardiometabolic and chronic diseases.

Peran Intensitas Latihan dalam Hipertrofi Otot Skeletal Irawati, Nur Ayu Virginia; Sylviana, Nova; Lubis, Leonardo
Jurnal Biomedika dan Kesehatan Vol 7 No 1 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.124-132

Endurance training, a form of physical activity that relies on continuous aerobic exercise and repetitive muscle contractions, is widely acknowledged for its positive effects on overall physical fitness. Aerobic exercise, an essential component of endurance training, has numerous benefits including improved cardiovascular and respiratory health, increased muscle endurance, and enhanced resistance against fatigue. It has also been found to contribute to skeletal muscles, potentially by stimulating the synthesis of proteins involved in muscle fiber formation. Although resistance exercise has been favored for promoting muscle growth, some suggests that aerobic exercise can also produce skeletal muscle hypertrophy comparable to that of resistance exercise if performed correctly. The duration, intensity, and specific type of aerobic exercise play important roles in determining skeletal muscle mass. The mammalian target of rapamycin (mTOR) known as a key regulator of muscle protein synthesis that associated with exercise activity. Several signaling pathways, such as Akt/mTOR and MAPK, are involved in controlling muscle protein synthesis during exercise. This review aimed to understand the impact of aerobic exercise intensity and other training parameters on skeletal muscle, to provide valuable insights for optimizing exercise programs and fostering muscle hypertrophy. In this review, we had systematically searched PubMed and Google Scholar from January 2013 to May 2023. Our result indicated that aerobic exercise can be expected to promote skeletal muscle hypertrophy and improve muscle mass and function. The regulation of skeletal muscle mass is complex, involving various signaling pathways such as mTOR, as well as the influence of hormones and growth factors.

Plant-based diet dan sindrom metabolik: uji pendahuluan pada komunitas plant-based diet Bandung Lubis, Leonardo; Luftimas, Dimas Erlangga; Faiza, Tiara; Fatimah, Siti Nur; Fitria, Nita; Purba, Ambrosius
Jurnal Gizi Klinik Indonesia Vol 21, No 2 (2024): Oktober
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.84198

Association between plant-based diet and metabolic syndrome: a pilot study on Bandung plant-based diet communityBackground: Metabolic syndrome is a cluster of disorders related to cardiometabolic abnormalities that are experienced by two out of five people in Indonesia. Miscellaneous factors increase the risk of metabolic syndrome, including improper diet. Plant-based diets are expected to lower the risk of metabolic syndrome.Objective: The study investigated the association between a plant-based diet and metabolic syndrome.Methods: A cross-sectional study design was conducted on 60 subjects, consisting of 20 subjects who applied the plant-based diet and 40 subjects who did not apply the plant-based diet. Visceral fat rating, body mass index, blood pressure, fasting blood glucose, triglyceride, and HDL were also measured to identify the amount of metabolic syndrome indicators that occurred in each subject. Data was analyzed using a parametric independent sample t-test, non-parametric Mann-Whitney U, and Chi-Square tests.Results: Non-parametric test analysis in fasting blood glucose showed a significant result (p=0.022), but not in other metabolic syndrome indicators, as well as the Chi-Square test (p=1.000).Conclusions: This study found no association between a plant-based diet and metabolic syndrome.

Co-Authors Ambrosius Purba Arviana Adamantina Putri Cynthia, Jessica Daniel Womsiwor Dimas Erlangga Luftimas Faiza, Tiara Fani, Regina Chintya Irawati, Nur Ayu Virginia Julistio T. B. Djais, Julistio T. B. Lucky Saputra, Lucky Lydyana, Lynna Lynna Lidyana Miftahurachman Miftahurachman, Miftahurachman Muhammad, Afan Maulana Mulya Nurmansyah Ardisasmita Mustari, Ryandika Elvereza Nandina Oktavia Nani Kurniani Nita Fitria Nova Sylviana Ong, Paulus Anam Permana, Noah Jefferson Putri, Azkane Adila Putri, Jesslyn Christianningrum Rahmat Budi Kuswiyanto, Rahmat Budi Rajamany, Thyviyaa Ramadhan, Wahyu Syahrul Rejeki, Purwo Sri Ronny Lesmana Rosdianto, Aziiz Mardanarian Rossanti, Rini Sadikin, Irma Suwandi Saputra, Yosi Wailan Setiawan Setiawan Shelly Iskandar Siti Nur Fatimah Tache, Nisrina Tarigan, Beltasar Tatang Muchtar Sutaryan Tetty Yuniati Vita Murniati Tarawan Vitriana Vitriana Widiyanti, Alvira Yahya, Nurain

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