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All Journal Jurnal Kesehatan Masyarakat Indonesia Jurnal Kedokteran Diponegoro Althea Medical Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Biomedicine and Translational Research Jurnal Kesehatan Andalas Biomedical Journal of Indonesia Jurnal Kedokteran dan Kesehatan Jurnal Medika Malahayati Medical and Health Science Journal JURNAL ANALIS LABORATORIUM MEDIK Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS AgriHealth: Journal of Agri-food, Nutrition and Public Health Jurnal Kedokteran Universitas Palangka Raya Jurnal Kesehatan Tambusai Jurnal Kedokteran Raflesia Jurnal PADAMU NEGERI (Pengabdian pada Masyarakat Bidang Eksakta) JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Jurnal Pengabdian Masyarakat As-salam Dikdimas : Jurnal Pengabdian Kepada Masyarakat Proceeding of Bengkulu International Conference on Health Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health Proceeding International Conference Of Innovation Science, Technology, Education, Children And Health

Debie Rizqoh

Departemen Mikrobiologi Dan Imunologi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Bengkulu

Author-ID : 3129078

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Other

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CLINICAL MANIFESTATION OF COVID-19 CO-INFECTION CASE IN BENGKULU CITY Debie Rizqoh; Enny Nugrahaeni; Jusup Endang; Mulya Sundari; Dessy Triana; Mardhatillah Sariyanti; Nikki Aldi Massardi
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 1 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i1.32666

Background: The COVID-19 pandemic is still ongoing, and no one could predict when it would end. In some cases of COVID-19, patients experienced infection by SARS-Cov-2 and other microorganisms, including viruses, bacteria, and fungi.Objective: This study aims to determine Co-infection on clinical symptoms and mortality of COVID-19 patients in Bengkulu City, Indonesia.Methods: We reviewed and analyzed data on patients with confirmed COVID-19 who were co-infected, including basic information, clinical manifestations, radiological and laboratory examinations, to the final status.Results: A total of 105 patients with confirmed COVID-19 participated in this study with various clinical manifestation: mild case (12%), moderate case/ mild pneumonia (52%), severe pneumonia (20%) and critical case (16%). Of the 105 patients, six patients were co-infected with human immunodeficiency virus (HIV) (1 case), Mycobacterium tuberculosis (2 cases), Salmonella thypii (2 cases), bacterial pneumonia, and viral pneumonia (1 case). As many as three of the six patients experienced inferior clinical manifestations and died.Conclusion: The co-infection of other microorganisms in COVID-19 can affect the severity and mortality in COVID-19 patients.

Trends in IgG Antibody Levels in Covid-19 Patients in Different Clinical Manifestations in Bengkulu City: Cohort Study Debie Rizqoh; Enny Nugrahaeni; Mulya Sundari; Dessy Triana; Mardhatillah Sariyanti; Nikki Aldi Massardi
AgriHealth: Journal of Agri-food, Nutrition and Public Health Vol 3, No 2 (2022): October
Publisher : Research and Development Center for Food, Nutrition and Public Health (P4GKM) LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/agrihealth.v3i2.61315

More than two years have lasted since the coronavirus disease 2019 (Covid-19) pandemic. The case of Covid-19 in Indonesia has spread to all provinces and areas such as Bengkulu City. This study aims to determine the profile of clinical manifestations and antibody dynamics in Covid-19 patients in Bengkulu City. This study used a cohort design on Covid-19 patients at two Bengkulu City referral hospitals, M. Yunus Hospital and Harapan dan Doa Hospital. Data on clinical manifestations were obtained from the medical records of Covid-19 patients. Meanwhile, to determine the level of IgM and IgG antibodies, patient serum samples were taken directly from respondents from the beginning of hospital admission three times on the 1st, 2nd and 3rd weeks. Then the samples were examined by immunofluorescent assay method. The results of this study indicate that, in general, there are no significant differences in anti-SARS-CoV-2 IgG levels in Covid-19 patients in the 1st, 2nd and 3rd weeks of Covid-19 in Bengkulu City. The Spearman correlation test also showed no correlation between IgG levels and the clinical manifestations of Covid-19. Although not statistically significant, there was a trend towards differences in antibody levels in patients with mild, moderate and severe clinical manifestations. The results of this study indicate that there are variations in antibody dynamics in Covid-19 patients in Bengkulu City.

Perbandingan Tingkat Keparahan Infeksi Primer Virus Dengue Serotipe 1, 2, 3 dan 4 di Indonesia: Systematic Review Mardhatillah Sariyanti; Nur Fitri; Ety Febrianti; Annelin Kurniati; Debie Rizqoh
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 6, No 1 (2021)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Dengue virus infection (DENV) circulates in various hyperendemic and endemic areas that has increase mortality year by year. Indonesia is the second-largest country which is endemic to dengue infection between 30 other countries in the world. There are four circulating dengue virus (DENV) serotypes, namely DENV-1, DENV-2, DENV-3, and DENV-4. Each serotype shows a different clinical manifestation and severity. This systematic review aims to compare the severity of dengue virus primary infection and serotype 1,2,3,and 4. Data were collected based on studies of the severity of primary infections caused by various DENV serotypes in Indonesia. Data was searched using a database in the form of Pubmed and Chocrane. The keywords used are (Primary dengue infection OR dengue primary infection) AND (serotype OR serogroup OR serotype dengue)) AND (severity OR severe dengue* OR severity of illness index* OR clinical manifestations OR clinical features OR clinical characteristics) AND Indonesia. Based on search results, we obtained 7 studies out of 699 studies. 7 studies found that there are differences in serotype circulation in Indonesia. DENV-3 is dominant in 7 cities in Indonesia, while DENV-1 is dominant in Surabaya, Bali, and Jambi. Dengue fever shows a greater percentage than DHF / DSS. The proportion of severity is lower in primary infections.

Potensi Bakteri Endofit Andaliman (Zanthoxylum Acanthopodium DC.) Menghambat Bakteri Penyebab Infeksi pada Manusia Debie Rizqoh; Wulan Okta Kumala; Sipriyadi Sipriyadi; Besly Sinuhaji; Oktoviani Oktoviani
JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) Vol 6, No 3 (2021)
Publisher : Prodi Kesehatan Masyarakat Fakultas Kesehatan Masyarakat UIN Sumatera Utara

Endophytic bacteria are a beneficial bacteria that live in plant tissue. Several studies have shown that certain endophytic bacteria can produce secondary metabolites that have health effects. The andaliman (Zanthoxylum acanthopodium DC) have several properties, one of which is as antibacterial against pathogenic bacteria. The most common bacterial infections in humans are caused by commensal bacteria in the body such as Escherichia coli and Staphylococcus aureus. This study used a qualitative data collection method with the type of experimental laboratory research to isolate the endophytic bacteria andaliman which had been tested against the pathogenic bacteria Escherichia coli and Staphylococcus aureus. The initial stage were isolation of endophytic bacteria and observation of colony characteristics, after obtaining isolates with different colony characteristics, a Gram stain test and a antagonist test for pathogenic bacteria were carried out. In this study, 252 colonies grew and there were 85 isolates with different colony characteristics. From all the isolates, there were two isolates that could inhibit the growth of Escherichia coli and seventeen isolates that could inhibit the growth of Staphylococcus aureus.

PENYULUHAN DAMPAK NEGATIF PENYALAHGUNAAN NARKOBA DI MASYARAKAT Debie Rizqoh; Rizkianti Anggraini; Diah Ayu Aguspa Dita
JPMA - Jurnal Pengabdian Masyarakat As-Salam Vol. 1 No. 1 (2021): Jurnal Pengabdian Masyarakat As-Salam (JPMA)
Publisher : Asosiasi Dosen Perguruan Tinggi Islam

Penyalahgunaan narkotika, psikotropika, dan zat adiktif lainya merupakan suatu permasalah yang dihadapi Indonesia tidak terkecuali di Kota Bengkulu dewasa ini. Para pemakai barang haram ini biasanya rentan atau resiko tinggi melanda individu muda yang dengan kepribadian labil. Jika hal ini tidak ditanggulangi dengan baik akan memicu gangguan kesehatan fisik, psikis, rendahnya kualitas hidup, gangguan fungsi sosial, ekonomi, budaya, hankam generasi muda kedepanya. Sektor medis atau pelaku kesehatan mempunyai andil penting dalam iktiar pengendalian penyalahgunaan NAPZA, lewat upaya promotif, preventif, terapi dan rehabilitasi. Dalam hal ini penulis melakukan penyuluhan kepada masyarakat kelurahan Pintu Batu, Kecamatan Teluk Segara, Kota Bengkulu mengenai NAPZA dan bentuk-bentuk NAPZA dalam upaya menagkal penggunaan narkoba dikalangan remaja maupun masyarakat.

Comparison of Widal Test Using Serum and Plasma Samples Debie Rizqoh; Roina Sitanggang
Biomedical Journal of Indonesia Vol. 7 No. 2 (2021): Vol 7, No 2, 2021
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i2.291

The widal test is a test for diagnostic of thyfoid fever serology. Widal test aims to detect the presence of antibodies against Salmonella antigen, by measuring the degree of agglutination of antibody titer to antigen O and H in sample. In this research Widal test was performed using serumand plasma samples. This study aims to determine whether there is a difference in the value of titer on the Widal test between serum samples and plasma EDTA samples. This type of research is an experimental study. Samples were taken from patient suspected of thyfoid fever of 10 sample in the Laboratory of SM Raja Amplas in 2018. The result of comparative titer Widal test using serum and plasma samples obtained results 30% of the 10 samples examined there are differences in the value of Widal titer but does not affect the final diagnosis of typhoid fever. The value of the Widal test titer using plasma is lower than the value of Widal Titer with the serum samples. The use of plasma samples to determine the Widal titer is particularity susceptible to mingling with the erythrocytes due to the presence of anticoagulant particles but does not affect the result of the Widal test. EDTA anticoagulants do not damage the antibodies contained in the serum, this can be seen in the results of the study, there were no differences in each sample examined, so the difference in results obtained due to other factors, namely the error of researchers in the Widal test. The Widal test using serum samples can gives results according to the actual circumstances because serum is not contaminated by EDTA anticoagulants.

IDENTIFIKASI BAKTERI Salmonella sp. PADA PENDERITA DEMAM TIFOID ANAK USIA 5-14 TAHUN DENGAN METODE WIDAL TEST DI RUMAH SAKIT ADVENT MEDAN TAHUN 2018 Mulya Sundari; Debie Rizqoh; Grace Junita Bate'e
Jurnal Analis Laboratorium Medik Vol 6 No 1 (2021): JURNAL ANALIS LABORATORIUM MEDIK
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jalm.v6i1.1893

Demam tifoid merupakan suatu penyakit sistemik akut yang disebabkan oleh Salmonella typhi, Salmonella paratyphi A, Salmonella paratyphi B dan Salmonella paratyphi C. Penularan demam tifoid terjadi secara fekal-oral melalui makanan dan minuman yang terkontaminasi yang masuk kedalam tubuh.Pada anak-anak demam tifoid dapat terjadi akibat kurang memperhatikan kebersihan diri dan kebiasaan jajan yang sembarangan sehingga dapat menyebabkan tertular penyakit demam tifoid.Telah dilakukan penelitian terhadap 10 serum penderita demam tifoid anak usia 5-14 tahun di Rumah Sakit Advent Medan, dengan identifikasi bakteri Salmonellamelalui Uji Widal.Hasil yang telah di peroleh yaitu 1 orang pasien positif terhadap Salmonella typhii;1 orang pasien positif terhadap Salmonella typhii dan Salmonella paratyphii B; 3 orang pasien positif terhadap Salmonella typhii, Salmonella paratyphii B dan Salmonella paratyphii C; 2 orang pasien positif terhadap Salmonella typhii, Salmonella paratyphii A dan Salmonella paratyphii C; 1 orang pasien positif terhadap Salmonella paratyphii A, Salmonella paratyphii B dan Salmonella paratyphii C dan2 orang pasien yang positif terhadap Salmonella typhii, Salmonella paratyphii A, Salmonella paratyphii B dan Salmonella paratyphii C. Dalam penelitian ini, sebagian besar pasien positif terhadap lebih dari 1 antigen Salmonella, hal ini dapat terjadi karena adanya reaksi silang sebelumnya dengan antigen antara spesies Salmonella yang sama yang memiliki antigen O faktor 12 atau pernah terinfeksi dahulu dengan salah satu spesies Salmonella.

KONTAMINASI Salmonella sp. PADA SOP BUAH YANG DIJUAL DI JALAN DR. MANSYUR KELURAHAN PADANG BULAN KOTA MEDAN Debie Rizqoh; Hamka Ismuda
Jurnal Analis Laboratorium Medik Vol 6 No 1 (2021): JURNAL ANALIS LABORATORIUM MEDIK
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jalm.v6i1.1894

Sop buah merupakan salah satu jenis minuman yang terdiri dari campuran berbagai macam buah, sirup, susu, air dan es. Ada beberapa faktor yang dapat menyebabkan perubahan manfaat sop buah menjadi sumber penyakit bagi tubuh meliputi: air sebagai bahan sop buah dan air yang digunakan untuk mencuci mangkok dan sendok dapat menjadi bahan kontaminasi penyebab penyakit seperti Salmonella sp. Tujuan penelitian ini adalah untuk mengidentifikasi Salmonella pada sop buah yang dijual di Jalan Dr. Mansyur Kelurahan Padang Bulan Selayang Medan Tahun 2018. Penelitian ini bersifat deskriptif dengan metode pembiakan dan reaksi biokimia. Populasi dalam penelitian ini seluruh sop buah yang diperjualbelikan di Jalan Dr. Mansyur kelurahan Padang Bulan Medan sebanyak 10 sampel. Dari 10 sampel yang diperiksa ada 2 yang terkontaminasi oleh bakteri Salmonella sp dengan kode sampel S1 dan S4. Hal ini terjadi karena air sop buah yang kurang hygenies dan sop buah tidak memenuhi syarat kesehatan dapat menimbulkan kontaminasi pada makanan.

Health Education About Clean and Healthy Lifestyle Behavior (PHBS) in the Transition Period of the Covid-19 Pandemic for Students Debie Rizqoh; Ellen Maidia Djatmiko; Nikki Aldi Massardi; Alvi Jalilul Hakim; Novita Arifani; Azella Chika Fauzia
DIKDIMAS : Jurnal Pengabdian Kepada Masyarakat Vol. 2 No. 1 (2023): DIKDIMAS : JURNAL PENGABDIAN KEPADA MASYARAKAT VOL 2 NO 1 APRIL 2023
Publisher : CV Media Inti Teknologi

After the COVID-19 pandemic is ongoing up to 3 years, finally Indonesia started experience transition from pandemic going to endemic, following decreasing of case positive for COVID-19. During the transition, a number of rule start relaxed, however government recommend public for still carry out health protocol. Besides, in field education, all school carry out 100 % offline learning. The students have to stay alert from COVID-19 infection or another infection. So that, clean and healthy lifestyle (PHBS) is necessary carried out at school. There are several indicators of PHBS in schools that are necessary known by students. This health education aims to give education to 97 students in schools especially at SMK Negeri 2 Bengkulu City about importance implementing PHBS in the transition period of COVID-19 pandemic. This activity took place on Thursday , 22 September 2022. The method used form give education and discussion regarding PHBS in schools. We evaluated student’s understanding by pre-test and post-test about PHBS. Participant generally already have own knowledge regarding PHBS and more understand PHBS after participated in this activity.

ANTIBODY IgG LEVELS AND ADVERSE EVENTS FOLLOWING IMMUNIZATION AFTER THIRD DOSE OF MODERNA VACCINE IN HEALTHWORKERS AFTER TWO DOSES OF SINOVAC VACCINE Ade Tiur Rumondang; Utari Hartati Suryani; Debie Rizqoh; Mardhatillah Sariyanti; Besly Sinuhaji
JURNAL KEDOKTERAN DAN KESEHATAN Vol 10, No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V10I2.20872

Health Care Workers (HCWs) are a top priority to receive the vaccination for Coronavirus Disease 2019 (Covid-19). After two doses of the Sinovac vaccine as the primary vaccine, protection against Covid-19 weakens over time, so a booster vaccination is considered to produce more antibodies. In addition, each vaccine is inseparable from Adverse Event Following Immunization (AEFI). This study compares antibody levels and AEFIs between two doses of the Sinovac vaccine with the Moderna booster. This research is an observational analytic study with a cross-sectional study design and the sampling method is random sampling with a total of 74 HCWs using a consecutive sampling method. Samples that had received two doses of the Sinovac vaccine or booster doses of the Moderna vaccine after two doses of the Sinovac vaccine were included. Samples that had been infected with Covid-19 before vaccination were excluded. IgG antibody levels were measured using Chemiluminescent Microparticle Immunoassay (CMIA), while vaccine type and AEFI were gathered via questionnaire. The severity of AEFIs is based on WHO classification. The data analysis used the Mann-Whitney and Chi-Square tests with a 95% Confidence Interval (CI) to determine the relationship between variables. Twenty-nine subjects received two doses of the Sinovac primary vaccine (38.2%), and forty-five received the Moderna booster vaccine (59.2%). In booster doses of the Moderna vaccine recipients, antibodies tended to be higher, and the most common AEFIs were systemic. There was a significant difference in IgG antibody levels between recipients of two doses of the Sinovac vaccine (median=2888.8 AU/mL) and booster Moderna vaccine recipients (median=18081.04 AU/mL) (p=0.000, p <0.05). There were significant differences in AEFI in the groups receiving two doses of the Sinovac vaccine and those receiving the booster vaccine (p=0.000, p<0.05). This study concludes that there is a significant correlation between administering the Covid-19 vaccine and post-vaccination IgG antibody levels and AEFI.

Co-Authors Ade Tiur Rumondang Ade Tiur Rumondang Adiansyah Ahmad Fandi Alvi Jalilul Hakim Ambarsarie, Riry Amelia, Aisyah Annelin Kurniati Annelin Kurniati Arifani, Novita Ashan, Hesty Rhauda Athalia , Nabila Wine Atik Prihatiningrum, Atik Atiqah, Rissya Febiona Azella Chika Fauzia Besly Sinuhaji Besly Sinuhaji Besly Sinuhaji Dendrinson Purba Dendrinson Purba Dessy Triana Dessy Triana Dessy Triana Diah Ayu Aguspa Dita Dian Handayani Djatmiko, Ellen Maidia Ellen Maidia Djatmiko Ellen Maidia Djatmiko Elvira Yunita Elvira Yunita Endang, Jusup Enny Nugrahaeni Enny Nugrahaeni Enny Nugraheni Enny Nugraheni Enny Nugraheni Enny, Nugraheni Ety Febrianti Ety Febrianti Fadlika, Rizki Fahira, Dita Fandi, Ahmad Fauzia, Azella Chika Febrianti, Ety Febrina, Olivia Putri Grace Junita Bate'e Gunasari, Lala Foresta Valentine Hakim, Alvi Jalilul Hamka Ismuda Hestina Hestina Iqbal, Maulana Jusup Endang Kumala, Wulan Okta Kurniati, Annelin Laudy, Nabila Putri Mardhatillah Sariyanti Mardhatillah Sariyanti Mardhatillah Sariyanti Mardhatillah Sariyanti Meidiyanti, Prima Mulya Sundari Mulya Sundari Mulya Sundari Mulya Sundari Mulya Sundari Mulya Sundari Nabilah, Putri Syifa Nikki Aldi Massardi Noor Diah Erlinawati Novita Arifani Nugraheni, Enny Nur Fitri Ocktaviani, Risti Dwi Oktavia Salsadillah Putri Oktavia Silalahi Oktoviani Oktoviani, Oktoviani Pratiwi, Ulfa Hanum Putri Maulida Rachmawati, Indah Dwi Ramadhani, Abdah Zhafirah Rizkianti Anggraini Roina Sitanggang Roina Sitanggang Sariyanti, Mardhatillah Sipriyadi Suryani, Utari Hartati Umar, Liya Agustin Utari Hartati Suryani Utari Hartati Suryani Wulan Okta Kumala

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