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All Journal JURNAL PHARMASCIENCE Majalah Obat Tradisional Jurnal Komputasi Jurnal Kreativitas PKM PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Jamu Indonesia Jurnal Pengabdian Kepada Masyarakat (Mediteg) Jurnal Ilmiah Farmako Bahari Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Abdiraja Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Bakti Untuk Negeri Benzena Pharmaceutical Scientific Journal Jurnal Pengabdian Masyarakat Panacea Indonesian Journal of Jamu Jurnal Komputasi Journal of Pharmascience
Liling Triyasmono
Program Studi Farmasi, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Lambung Mangkurat, Banjarbaru
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Journal of Pharmascience

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Karakteristik Fisika Sediaan Suspensi Ekstrak Etanol Daun Gaharu (Aquilaria microcarpa Baill.) dengan Variasi Carboxymethyl Cellulose Sodium (CMC-Na) Mia Fitriana; Wawan Halwany; Khoerul Anwar; Liling Triyasmono; Beny Rahmanto; Susy Andriani; Nur Ainah
Journal of Pharmascience Vol. 7 No. 1 (2020): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v7i1.8087

Abstract

ABSTRAK Gaharu (Aquilaria microcarpa Baill.) merupakan salah satu hasil hutan yang memiliki aktivitas antioksidan. Ekstrak etanol daun A. microcarpa terbukti memiliki aktivitas antioksidan yang tergolong sangat aktif. Ekstrak etanol daun A. microcarpa kemudian dibuat menjadi sediaan suspensi dengan variasi CMC-Na sebagai agen pengsuspensi. Penelitian ini bertujuan untuk menentukan pengaruh konsentrasi CMC-Na terhadap karakteristik fisik suspensi ekstrak etanol daun A.microcarpa. Suspensi dibuat dengan variasi CMC-Na pada F1 (0,5% CMC-Na), F2 (1% CMC-Na) dan F3 (1,5% CMC-Na). Evaluasi sediaan suspensi meliputi organoleptis, uji viskositas, uji pH, uji homogenitas serta uji berat jenis suspensi. Nilai evaluasi suspensi dianalisis secara statistik dengan software SPSS 21. Hasil evaluasi fisik menunjukkan bahwa penambahan  konsentrasi CMC-Na akan meningkatkan nilai viskositas dan berat jenis sediaan. Kesimpulan dari pengujian ini adalah variasi konsentrasi CMC-Na mempengaruhi hasil viskositas, serta berat jenis suspensi (p<0,05) dan tidak mempengaruhi hasil organoleptis, homogenitas dan pH suspensi.  Kata kunci: Gaharu, suspensi, CMC-Na  ABSTRACT Gaharu (Aquilaria microcarpa Baill.) is one of the Borneo’s forest products that has antioxidant activity. Ethanol extract of A. microcarpa folium has been shown to have antioxidant activity that is classified as very active. The ethanol extract of A. microcarpa folium was then made into a suspension preparation with variations of sodium CMC as a suspending agent. This study aimed to determine the effect of sodium CMC concentration on the physical characteristics of the ethanol extract of A.microcarpa folium. Suspension was made with variations of sodium CMC in F1 (0.5% sodium CMC), F2 (1% sodium CMC) and F3 (1.5% sodium CMC). Evaluation of suspension preparations included organoleptic, viscosity test, pH test, homogeneity test and suspension specific gravity test. The suspension evaluation data were analyzed statistically with SPSS 21 Software.  The physical evaluation results showed that the addition of sodium CMC concentration would increase the viscosity and specific gravity of the preparation. The conclusion of this test was that variations in the concentration of sodium CMC affected the results of viscosity and suspension specific gravity (p <0.05) and did not affect the organoleptic yield, homogeneity and pH of the suspension. Keywords: Gaharu, suspension, 
Co-Authors Abda Abda Abdul Gafur Agung Endro Nugroho Agung Nugroho Agustina, Ni Kadek Ayu Akbar, Nabila Hadiah Alfandani, Gina Alifni Adha Bakti Amali, Dzikra Aulia Ana Ulfah Anna Khumaira Sari Anna Khumaira Sari Arnida Arnida Arnida Arnida Beny Rahmanto Beny Rahmanto Beny Rahmanto Budi Prayitno Budi Prayitno Buih, Putri Helena Junjung Destria Indah Sari Dewi, Anita Ratna Dewita Fitri Widodo Difa Intannia Dika Wardana, Dika Dina Rahmawanty Dodon Turianto Nugrahadi Effendi, Ibrahim Rully Eko Suhartono Evi Mintowati Evi Mintowati Kuntorini Evi Mintowati Kuntorini Evi Mintowati, Evi Fajar Lestari Fajar Lestari Fajar Lestari Gina Alfandani Gunawan Gunawan Gunawan Gunawan Hayatun Izma Helmina Wati Heri Budi Santoso Herningtyas Nautika Lingga Humaidy, Mizan Irvan Ipand Irvan Ipandi, Irvan Izma, Hayatun Khoerul Anwar Khoerul Anwar Khoerul Anwar Khoerul Anwar Khumaira Sari, Anna Laura Sarwo Malahayati, Siti Malikhatun Ni’mah, Malikhatun Malikhatun Ni’mah Malikhatun Ni’mah Maman Turjaman Maman Turjaman Mia Fitriana Muhammad Ikhwan Rizki Muhammad Janawi Muhammad Reza Faisal, Muhammad Reza Muslimah Muslimah Mutia Mawaddah Nazhipah Isnani Noor Rizkiyah Normaidah, Normaidah Nugroho, Agung Nur Ainah Nur Mahdi Nuraji, Tara Pramesti Nurlely Nurlely Nurlely, Nurlely Ori Minarto Rahmah, Indah Noor Rahmanto, Beny Rahmatullah, Satrio Wibowo Rahmi Safitri Rahmi Safitri, Rahmi Ratnapuri, Prima Happy Redanti, Hema Novita Rorry Adivrio Rizky S.Pd. M Kes I Ketut Sudiana . Salamiah . Salamiah Salamiah Salsabilla, Risma Zahra Salwa, Helmina Samsul Hadi Sandi, Dita Ayulia Dwi Sarlina Illyyani Sarlina Illyyani, Sarlina Selamat Alfiani, Selamat Sofia Sri Cahyo Wahyono Sudarsono Sudarsono Susiani, Eka Fitri Susy Andriani Sutomo Sutomo Sutomo Sutomo Sutomo Sutomo Totok Wianto Veithzal Rivai Zainal Wawan Halwany Wawan Halwany Wawan Halwany Wawan Halwany, Wawan