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All Journal JURNAL PHARMASCIENCE Majalah Obat Tradisional Pharmascience Jurnal Komputasi Jurnal Kreativitas PKM PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JCPS (Journal of Current Pharmaceutical Sciences) Jurnal Jamu Indonesia Jurnal Pengabdian Kepada Masyarakat (Mediteg) Jurnal Ilmiah Farmako Bahari Borneo Journal Of Pharmascientech Jurnal Insan Farmasi Indonesia Jurnal Abdiraja Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Bakti Untuk Negeri Benzena Pharmaceutical Scientific Journal Jurnal Pengabdian Masyarakat Panacea Indonesian Journal of Jamu
Liling Triyasmono
Program Studi Farmasi, Fakultas Matematika Dan Ilmu Pengetahuan Alam, Universitas Lambung Mangkurat, Banjarbaru
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Pharmascience

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Kandungan Total Fenolik, Total Flavonoid, dan Aktivitas Antioksidan Ekstrak Etanol Buah Mengkudu (Morinda citrifolia L.) Khoerul Anwar; Liling Triyasmono
Jurnal Pharmascience Vol 3, No 1 (2016): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v3i1.5838

Abstract

ABSTRAK  Buah mengkudu (Morinda citrifolia L.) merupakan salah satu tanaman mempunyai khasiat meningkatkan daya tahan tubuh, menurunkan tekanan darah, menurunkan glukosa darah, dan sebagai antibakteri. Penelitian ini bertujuan untuk menentukan kandungan total fenolik, total flavonoid, dan aktivitas antioksidan ekstrak etanol buah mengkudu. Serbuk kering buah mengkudu dimaserasi menggunakan etanol 70%.  Analisis kualitatif fenolik dan flavonoid dilakukan dengan kromatografi lapis tipis (KLT). Penetapan kadar total fenolik menggunakan pereaksi Folin-ciocalteau dengan pembanding pirogalol. Kadar total flavonoid ditetapkan dengan pembanding rutin menggunakan pereaksi FeCl3. Aktivitas antioksidan ditentukan dengan uji penangkapan radikal 2,2-difenil-1-pikrilhidrazil (DPPH). Hasil analisis kualitatif menunjukkan adanya kandungan senyawa fenolik dan flavonoid. Kadar total fenolik pada ekstrak etanol buah mengkudu sebesar 14,44+0,82 mg ekivalen  pirogalol  (PE)/g  ekstrak, sedangkan kadar total flavonoid sebesar 5,69+0,21  mg ekivalen rutin (RE)/g ekstrak. Hasil uji aktivitas antioksidan dengan metode DPPH menunjukkan IC50 ekstrak etanol buah mengkudu sebesar 104,73+4,56  µg/mL. Kata kunci: Morinda citrifolia, total fenolik, total flavonoid, antioksidan  ABSTRACT Noni (Morinda citrifolia L.) is one of the plants have properties to increase endurance, lower blood pressure, lowering blood glucose, and as an antibacterial. The aim of this study is to determine the total phenolic content, total flavonoids and antioxidant activity of ethanol extract of noni. Dry powder of noni fruit macerated using 70% ethanol. Qualitative analysis of total phenolic and total flavonoid was done by thin layer chromatography (TLC). Total phenolic assay used Folin-ciocalteau reagent by pyrogallol as comparison. Levels of total flavonoids determined by comparison to the rutin use of FeCl3 reagent. The antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH). The results of the qualitative analysis showed that it contains phenolic compounds and flavonoids. Total phenolic content of the ethanol extract of noni at 14.44+0.82 mg pyrogallol equivalent (PE) / g extract, while the total flavonoid content of 5.69+0.21 mg equivalent routine (RE) / g extract. The test results of antioxidant activity with DPPH method showed IC50 ethanol extract of noni of 104.73+4.56 µg / mL.Key words: Morinda citrifolia, total phenolic, total flavonoids, antioxidant
Co-Authors Abdul Gafur Agung Endro Nugroho Agung Nugroho Agustina, Ni Kadek Ayu Akbar, Nabila Hadiah Alfandani, Gina Alifni Adha Bakti Amali, Dzikra Aulia Ana Ulfah Anna Khumaira Sari Anna Khumaira Sari Arnida Arnida Arnida Arnida Beny Rahmanto Beny Rahmanto Beny Rahmanto Budi Prayitno Buih, Putri Helena Junjung Destria Indah Sari Dewi, Anita Ratna Dewita Fitri Widodo Difa Intannia Dika Wardana, Dika Dina Rahmawanty Dodon Turianto Nugrahadi Effendi, Ibrahim Rully Eko Suhartono Evi Mintowati Evi Mintowati Kuntorini Evi Mintowati Kuntorini Evi Mintowati, Evi Fajar Lestari Fajar Lestari Fajar Lestari Gina Alfandani Gunawan Gunawan Gunawan Gunawan Hayatun Izma Helmina Wati Heri Budi Santoso Herningtyas Nautika Lingga Humaidy, Mizan Irvan Ipand Irvan Ipandi, Irvan Izma, Hayatun Khoerul Anwar Khoerul Anwar Khoerul Anwar Khoerul Anwar Khumaira Sari, Anna Laura Sarwo Malahayati, Siti Malikhatun Ni’mah, Malikhatun Malikhatun Ni’mah Maman Turjaman Maman Turjaman Mia Fitriana Muhammad Ikhwan Rizki Muhammad Janawi Muhammad Reza Faisal, Muhammad Reza Muslimah Muslimah Mutia Mawaddah Nazhipah Isnani Normaidah, Normaidah Nugroho, Agung Nur Ainah Nur Mahdi Nuraji, Tara Pramesti Nurlely Nurlely Nurlely, Nurlely Ori Minarto Rahmah, Indah Noor Rahmanto, Beny Rahmatullah, Satrio Wibowo Rahmi Safitri Rahmi Safitri, Rahmi Ratnapuri, Prima Happy Redanti, Hema Novita Rizkiyah, Noor Annisa Rorry Adivrio Rizky S.Pd. M Kes I Ketut Sudiana . Salamiah . Salamiah Salamiah Salsabilla, Risma Zahra Salwa, Helmina Samsul Hadi Sandi, Dita Ayulia Dwi Sarlina Illyyani Sarlina Illyyani, Sarlina Selamat Alfiani, Selamat Sofia Sri Cahyo Wahyono Sudarsono Sudarsono Susiani, Eka Fitri Susy Andriani Sutomo Sutomo Sutomo Sutomo Totok Wianto Veithzal Rivai Zainal Wawan Halwany Wawan Halwany Wawan Halwany Wawan Halwany, Wawan