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Correlation Between C-Reactive Protein Level and Outcome In Coronavirus Disease 2019 Patients At COVID Intensive Care Unit RSUP. Dr. M. Djamil Padang Putri Ariani; Dedy Kurnia; Malinda Meinapuri; Rudy Afriant; Rina Gustia; Rikarni; Rinal Effendi
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 11 No. 3 (2023): Jambi Medical Journal: Jurnal Kedokteran dan Kesehatan Special Issues: Jambi M
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v11i3.25078

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is a respiratory system disease transmitted to humans and has infected humans in almost every country. Plasma cytokine levels, such as C-reactive protein (CRP), are elevated inflammatory markers in most COVID-19 patients and are routinely examined, especially in the intensive care Unit (ICU). Elevated CRP levels are associated with higher rates of severity and death. Objective: This study aimed to determine the correlation between CRP levels and outcomes in COVID-19 patients at COVID ICU RSUP. Dr. M. Djamil Padang Period July – December 2021. Method: This research was conducted using by analytic observational method with a retrospective cohort design. Secondary data was collected from the medical records of COVID-19 patients treated in the ICU COVID RSUP. Dr. M. Djamil Padang from July – December 2021, using total sampling as a technique, 107 samples met the inclusion criteria. Data analysis was carried out using univariate and bivariate methods. Result: The result shows more male patients (51.4%) than women (48.6%). From the age range, most age was found in the range > 59 years (54.2%). The most common type of comorbid disease was diabetes (32.7%). The highest CRP level at the initial ICU admission was >160 mg/L (70.1%), and the highest ferritin level was >434 ng/mL (86.0%). The most common patient outcome was death (65.4%). There is a relationship between CRP levels (p = 0.029) and the outcome of COVID-19 patients in the COVID ICU. Conclusion: This study concludes that there is a correlation between C-Reactive Protein (CRP) levels and Outcomes in COVID-19 patients at COVID ICU RSUP. Dr. M. Djamil Padang Period July – December 2021. Keywords : COVID-19, CRP, Patient Outcome, ICU
Hubungan Rasio Neutrofil Limfosit, Rasio Platelet Limfosit, dan Rasio Limfosit Monosit dengan Stadium Klinis Karsinoma Nasofaring di RSUP Dr. M. Djamil Padang Periode 2020-2022 Rahman, Rifna Alya; Rahman, Sukri; Almurdi, Almurdi; Yusri, Elfira; Meinapuri, Malinda; Irawati, Lili
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 3 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v3i1.56

Abstract

Karsinoma nasofaring merupakan penyakit kanker ke-5 tersering di Indonesia yang berkaitan dengan infeksi Virus Epsteinn-Barr. Rasio neutrofil limfosit (RNL), rasio platelet limfosit (RPL), rasio limfosit monosit (RLM) merupakan biomarker inflamasi yang dapat mewakili respon inflamasi sehingga dapat menggambarkan progresivitas kanker. Stadion klinis juga digunakan untuk menentukan progresivitas kanker. Penelitian ini bertujuan untuk mengetahui hubungan RNL, RPL, dan RLM dengan stadium klinis karsinoma nasofaring. Penelitian ini menggunakan desain penelitian cross sectional dengan menggunakan data rekam medis pasien di RSUP Dr. M. Djamil Padang. Pengambilan sampel dilakukan dengan teknik konsekutif sampling. Total sampel yang digunakan sebanyak 64 sampel. Uji statistik menggunakan uji Chi-square. Hasil penelitian ini diperoleh kasus karsinoma nasofaring lebih banyak terjadi pada jenis kelamin laki-laki (65,6%), kelompok umur 25–49 tahun dan terdiagnosis pada stadium IV A. Hasil pemeriksaan darah rutin berada pada rentang normal yaitu neutrofil (51,5 %), limfosit (76,9%), monosit (57,8%), dan trombosit (54,7%). Nilai RNL, RPL, dan RLM mengalami peningkatan yaitu RNL (85,9%), RPL (68,8%), dan RLM (50%). Hasil uji Chi-square yang diperoleh tidak ada hubungan RNL (p>0,05), RPL (p>0,05), dan RLM (p>0,05) dengan stadion klinis. Dari penelitian ini disimpulkan bahwa tidak terdapat hubungan yang signifikan antara RNL, RPL dan RLM dengan stadion klinis KNF di RSUP Dr. M. Djamil Padang.
Profil Infeksi Blastocystis sp. pada Penderita Karsinoma Kolorektal Izzati, Ruhilda; Nofita, Eka; Suchitra, Avit; Rusjdi, Selfi Renita; Rustam, Rony; Meinapuri, Malinda
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 15, No 3 (2024): Juli-September 2024
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf15349

Abstract

Blastocystis sp. is one of the intestinal parasites that are often found in humans that cause digestive system disorders. Blastocystis sp. infection is thought to initiate the development of colorectal carcinoma because it induces inflammation in the gastrointestinal tract. This study aimed to determine the picture of Blastocystis sp. infection in colorectal carcinoma patients at Dr. M. Djamil Padang General Hospital. This study was a descriptive study, which was conducted at Dr. M. Djamil Padang General Hospital and the Parasitology Laboratory of the Faculty of Medicine, Andalas University with a sample size of 47 patients with colorectal carcinoma, who were selected using consecutive sampling techniques. The incidence of Blastocystis sp. infection was determined by microscopic examination of feces. Data were analyzed descriptively in the form of frequency tables and percentages. The results showed the incidence of Blastocystis sp. infection. in patients with colorectal carcinoma was 19.1%, most of whom were male (77.8%), under 50 years of age (44.5%), and generally had loose stool consistency (66.7%). Furthermore, it was concluded that the incidence of Blastocystis sp. infection in patients with colorectal carcinoma was quite high.Keywords: Blastocystis sp. infection; colorectal carcinoma; stool examination ABSTRAK Blastocystis sp. merupakan salah satu parasit usus yang sering ditemukan pada manusia yang menimbulkan gangguan sistem pencernaan. Infeksi Blastocystis sp. diduga dapat menginisiasi berkembangnya karsinoma kolorektal karena menginduksi inflamasi pada traktus gastrointestinal. Penelitian ini bertujuan untuk mengetahui gambaran infeksi Blastocystis sp. pada penderita karsinoma kolorektal di RSUP Dr. M. Djamil Padang. Penelitian ini adalah studi deskriptif, yang dilaksanakan di RSUP Dr. M. Djamil Padang dan Laboratorium Parasitologi Fakultas Kedokteran Universitas Andalas dengan ukuran sampel 47 pasien dengan karsinoma kolorektal, yang diseleksi dengan teknik consecutive sampling. Kejadian infeksi Blastocystis sp. Ditentukan dengan pemeriksaan tinja secara mikroskopis. Data dianalisis secara deskriptif berupa tabel frekuensi dan persentase. Hasil penelitian menunjukkan angka kejadian infeksi Blastocystis sp. pada penderita karsinoma kolorektal adalah 19,1%, yang sebagian besar berjenis kelamin laki-laki (77,8%), berusia di bawah 50 tahun (44,5%), dan konsistensi tinja umumnya encer (66,7%). Selanjutnya disimpulkan bahwa kejadian infeksi Blastocystis sp. pada pasien dengan karsinoma kolorektal cukup tinggi.Kata kunci: infeksi Blastocystis sp.; karsinoma kolorektal; pemeriksaan tinja
HUBUNGAN KADAR D-DIMER DENGAN DERAJAT KEPARAHAN PENYAKIT DAN ANGKA KEMATIAN PASIEN CORONAVIRUS DISEASE 2019 Trisuliandre, Muhammad Rizki; Herman, Deddy; Yulistini, Yulistini; Efrida, Efrida; Meinapuri, Malinda; Hasmiwati, Hasmiwati
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 2 No. 1 (2025): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Maret 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/empiris.v2i1.973

Abstract

Objective: This study aims to determine the relationship between D-dimer levels and the severity of the disease and the mortality rate of Coronavirus Disease 2019 patients treated at Dr. M. Djamil Padang General Hospital for the period June-August 2021. Method: This type of research is observational analytic using a retrospective cohort study design by taking a sample of 75 people through medical record data. Results: Most of the characteristics of the Coronavirus Disease 2019  patients were found in the age group of 56-65 years, male sex, most of them had an increased D-dimer value, and most of the patients did not die. This study found that there is a relationship between D-dimer levels and the severity of the disease and the mortality rate of Coronavirus Disease 2019 patients. Based on the Odd Ratio value obtained of 2.04 (1.53-2.71), it can be interpreted that people who have D -dimer increases have a risk of dying 2 times. Conclusion: There is a relationship between D-dimer levels and the severity of the disease and the mortality rate of 2019 Coronavirus Disease patients at Dr. M. Djamil Padang for the June-August 2021 period.
Perbandingan Nilai Diagnostik Menggunakan Real Time Polymerase Chain Reaction dan Kultur Sebagai Baku Emas dalam Mendeteksi Mycobacterium tuberculosis Tyas, Syanindhita Wikanthining; Linosefa, Linosefa; Tri Anggraini, Fika; Eka Putra , Andani; Bahar, Elizabeth; Arisanty, Dessy; Meinapuri, Malinda
Jurnal Ilmu Kesehatan Indonesia Vol. 6 No. 2 (2025): Juni 2025
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v6i2.1400

Abstract

Latar Belakang: Tuberkulosis merupakan penyakit menular yang disebabkan oleh Mycobacterium tuberculosis yang menduduki peringkat kedua penyebab kematian terbanyak. Faktor yang menyebabkan tingginya angka kejadian adalah keterlambatan dalam penegakan diagnosis. Pemeriksaan baku emas untuk tuberkulosis adalah kultur Lowenstein-Jensen yang membutuhkan waktu cukup lama untuk pertumbuhan koloni bakteri. Objektif: Penelitian ini bertujuan untuk mengetahui sensitivitas dan spesifisitas dari RT PCR menggunakan kit RT PCR yang bermerk Kit Crown Lab TB Dx dibandingkan dengan Kultur Lowenstein-Jensen. Metode: Penelitian ini menggunakan metode pendekatan cross-sectional dengan teknik purposive sampling sebanyak 87 sampel dari data sekunder yang diolah dan dianalisis dengan rumus uji diagnostik. Hasil: Hasil RT PCR didapatkan nilai positif 44 orang (50,6%) dan nilai negatif 43 orang (49,4%). Kultur Lowenstein- Jensen didapatkan nilai positif 43 orang (49,4%) dan nilai negatif 44 orang (50,6%). Hasil perbandingan kedua metode didapatkan nilai sensitivitas sebesar 97%, spesifisitas 95%, nilai duga positif 95%, dan nilai duga negatif 97% Kesimpulan: Kesimpulan dari penelitian ini Real Time PCR memiliki sensitivitas, spesifisitas, dan nilai duga positif dan negatif yang tinggi dan memiliki kelebihan waktu pemeriksaan yang lebih cepat dibandingkan pemeriksaan dengan Kultur Lowenstein-Jensen.  
Faktor Determinan Perilaku Deteksi Dini Kanker Payudara dengan SADARI pada WUS di Puskesmas Padang Pasir Ginting, Desi Scorpinasari; Asri, Aswiyanti; Karmia, Hudila Rifa; Hilbertina, Noza; Meinapuri, Malinda; Hasmiwati, Hasmiwati
Jurnal Kesehatan Komunitas Vol 11 No 2 (2025): Jurnal Kesehatan Komunitas
Publisher : LPPM Hang Tuah Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25311/keskom.Vol11.Iss2.2267

Abstract

Breast cancer is the most commonly diagnosed cancer globally, accounting for nearly 12% of all cases. One in eight women worldwide is at risk of developing breast cancer. Regular Breast Self-Examination (BSE) is one of the most effective methods for early detection. This study aimed to identify the determinants of early breast cancer detection behavior through BSE among women of reproductive age. The study found significant associations between BSE behavior and several predisposing factors, including education level (p = 0.002), knowledge (p = 0.000), perception (p = 0.009), attitude (p = 0.024), and motivation (p = 0.016); enabling factor, namely information exposure (p = 0.000); and reinforcing factors, including family support (p = 0.001) and support from health workers (p = 0.027). Conversely, there was no significant association between social support and BSE behavior (p = 0.394). The study concludes that predisposing, enabling, and reinforcing factors are significantly associated with BSE behavior. Information exposure is identified as the most influential determinant of BSE behavior among women in the working area of Padang Pasir Public Health Center.
Analysis of Risk Factors of Parenting Patterns using the Nurturing Care Framework Approach with the Incident of Stunting in Toddlers in a Case Study in the Working Area of Pagambiran Public Health Center Amilia, Fenni; Masrul, Masrul; Yusrawati, Yusrawati; Lipoeto, Nur Indrawaty; Mariko, Rinang; Meinapuri, Malinda
Journal La Medihealtico Vol. 6 No. 5 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i5.2532

Abstract

Stunting is a linear growth disorder caused by malnutrition and recurrent infections. Prevention is through the Nurturing Care Framework (NCF) approach, which includes health care, adequate nutrition, responsive care, early learning opportunities, and safety and security. This study aims to analyze the relationship between NCF-based parenting risk factors and stunting among toddlers in the Pagambiran Padang Community Health Center (Puskesmas) work area. This study was analytical with a cross-sectional design, conducted from June 2024 to January 2025. Sampling used stratified random sampling and simple random sampling, totaling 214 toddlers aged 24-59 months. Data collection used a questionnaire and was analyzed using univariate, bivariate (chi-square), and multivariate (multiple logistic regression with the backward elimination method). The results showed a stunting prevalence of 43.9%. Parenting patterns using the NCF (composite) approach were less than good at 55.1%. Multivariate analysis showed that risk factors significantly associated with stunting were health care (p=0.011), adequate nutrition (p=0.000), and safety and security (p=0.023). Adequate nutrition was the dominant factor (OR=8.602). Meanwhile, early stimulation and responsive parenting did not show a significant relationship. The conclusion of this study is that there is a relationship between health care, adequate nutrition, and safety and security with stunting. Adequate nutrition is the dominant factor. Cross-sectoral collaboration is expected to address nutritional issues, provide basic health services, monitor growth and development, and implement a healthy environment based on the National Child Protection Framework (NCF).
Evaluasi Pelaksanaan Program Antenatal Care (ANC) Terpadu di Kabupaten Kerinci Rizola, Clodeya; Firdawati, Firdawati; Aladin, Aladin; Sriyanti, Roza; Ramadani, Mery; Meinapuri, Malinda
MAHESA : Malahayati Health Student Journal Vol 5, No 9 (2025): Volume 5 Nomor 9 (2025)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v5i9.22208

Abstract

ABSTRACT The Sustainable Development Goals (SDGs) emphasize the reduction of the maternal mortality rate (MMR) to 70 per 100,000 live births by 2030. Despite various efforts, the MMR in Indonesia, including in Kerinci Regency, remains high. Integrated Antenatal Care (ANC) has become a key strategy in reducing maternal mortality. This study aims to evaluate the implementation of integrated ANC services in Kerinci Regency and to explore the influencing factors, including aspects of policy, input, process, and output. This research employed a qualitative approach. Informants included the Regent, Head of the District Health Office, and health workers from community health centers (Puskesmas) with the highest and lowest ANC coverage, those contributing to maternal mortality cases, and those with no reported cases. Data were collected through interviews, observations, and document review. The findings revealed that there is no specific policy regarding integrated ANC services. Implementation is hindered by a shortage of trained medical personnel and the absence of dedicated funding. The service delivery process does not fully adhere to established Standard Operating Procedures (SOPs) and remains largely top-down in planning, although coordination among health workers is relatively strong. While pregnant women reported high levels of satisfaction, the coverage of key ANC indicators (K1 and K5) remains suboptimal. In conclusion, the implementation of integrated ANC services in Kerinci Regency remains suboptimal due to various constraints in policy, input, process, and output components. This study highlights the need for short- to long-term interventions and provides in-depth insights into the challenges of implementing integrated ANC in resource-limited settings.  Keywords: Antenatal Care, Health Policy, Maternal Mortality, Program Evaluation  ABSTRAK Tujuan Pembangunan Berkelanjutan (SDGs) menekankan penurunan angka kematian ibu (AKI) 70/100.000 kelahiran hidup pada tahun 2030. Berbagai upaya telah dilakukan, AKI di Indonesia, termasuk di Kabupaten Kerinci, masih tinggi. Antenatal Care (ANC) terpadu menjadi salah satu strategi penting dalam penurunan AKI. Penelitian ini bertujuan untuk mengevaluasi pelaksanaan pelayanan ANC terpadu di Kabupaten Kerinci serta mengeksplorasi faktor-faktor yang memengaruhinya, termasuk kebijakan, input, proses, dan output. Penelitian ini menggunakan pendekatan kualitatif. Informan terdiri dari Bupati, Kepala Dinas Kesehatan, serta petugas dari Puskesmas dengan cakupan ANC tertinggi, terendah, penyumbang AKI, dan tanpa kasus AKI. Data dikumpulkan melalui wawancara, observasi, dan dokumentasi. Hasil penelitian menunjukkan bahwa belum terdapat kebijakan khusus mengenai ANC terpadu, dan implementasi masih terkendala keterbatasan tenaga medis terlatih serta ketiadaan pendanaan khusus. Proses pelaksanaan belum sepenuhnya sesuai SOP dan masih didominasi perencanaan top-down, meskipun koordinasi antar petugas sudah berjalan cukup baik. Capaian indikator K1 dan K5 belum optimal, meskipun kepuasan ibu hamil tergolong tinggi. Kesimpulan penelitian ini bahwa pelaksanaan pelayanan ANC terpadu di Kabupaten Kerinci belum optimal dan masih menghadapi berbagai hambatan pada aspek kebijakan, input, proses, maupun output. Implikasi dari penelitian ini menunjukkan perlunya intervensi jangka pendek seperti rekrutmen, redistribusi dokter dan sosialisasi SOP, intervensi jangka menengah berupa pelatihan berjenjang dan penguatan pendanaan, serta intervensi jangka panjang melalui penguatan kebijakan daerah yang mendukung penurunan AKI Kata kunci: Antenatal Care Terpadu, Kebijakan Kesehatan, Angka Kematian Ibu, Evaluasi Program