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All Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indian Journal of Forensic Medicine & Toxicology Forum Ilmiah Pendidikan Akuntansi (FIPA) Research of Service Administration Health and Sains Healthys Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Buletin Pengabdian Folia Medica Indonesiana Buletin Pengabdian
Lukitasari, Lina
Department Of Physiology And Biochemistry, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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PRELIMINARY LABORATORY EVALUATION OF RAPID DIAGNOSTIC TEST PROTOTYPE TO DETECT HBsAg IN WHOLE BLOOD AND SERUM Qurnianingsih, Ema; Wungu, Citrawati Dyah Kencono; Amin, Mochammad; Setyawati, Dewi; Yasan, Yanna Debby Restifanny; Lukitasari, Lina; Lusida, Maria Inge; Soetjipto, Soetjipto
Folia Medica Indonesiana Vol. 61, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Chronic hepatitis B virus (HBV) remains a major global health issue,[-10pc]AU: Please provide ORCID ID for all authors.[-7pc]AU: Please provide affiliation’s for all authors. with over 250 million people affected worldwide. In Indonesia, HBV prevalence has declined from high to moderate endemicity, but challenges persist due to regional disparities, risk of mother-to-child transmission, and the predominance of B3 and C1 sub-genotype. Despite available preventive measures and diagnostic tools, approximately 90% of cases remain undiagnosed, particularly in low-resource settings, indicating the need for improved screening and control strategies. Therefore, this study aims to conduct preliminary performance tests of KODC hepatitis B surface antigen (HBsAg) (rapid diagnostic test (RDT) prototype) produced by Konimex on serum and whole blood samples. Performance was assessed through sensitivity, precision, specificity, and comparative testing against commercial RDT. The results obtained were visually interpreted by 2 independent readers. KODC HBsAg RDT demonstrated a detection limit of 50 IU/ml in serum and 400 IU/ml in whole blood. Precision testing showed high reproducibility (RSD <3.02%), with no cross-reactivity against other pathogens. Compared with a commercial RDT, it showed equivalent performance in serum and superior specificity in whole blood. In addition, predictive value analysis confirmed excellent accuracy, with Positive predictive value (PPV) and negative predictive value (NPV) >99% in both sample types. Therefore, KODC HBsAg RDT prototype showed comparable performance to commercial tests with good sensitivity, precision, and specificity, indicating its potential as a practical tool for HBV screening in resource-limited settings.
Effect of Bay Leaf Extract (Syzygium polyanthum) on Blood Glucose, Malondialdehyde, and Insulin Levels in Animal Models of Diabetes: A Systematic Review Santoso, Brian Nathaniel; Rochmanti, Maftuchah; Lukitasari, Lina
Research of Service Administration Health and Sains Healthys Vol 6, No 2 (2025): Research of Service Administration Health and Sains Healthys (Desember)
Publisher : Lembaga Penelitian dan Pendidikan (LPP) Mandala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58258/rehat.v6i2.10008

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion or action. Long-term antidiabetic therapy may cause adverse effects, highlighting the need for safer alternative treatments. Syzygium polyanthum (bay leaf) contains various bioactive compounds with antidiabetic and antioxidant activities. This study aimed to evaluate the effects of Syzygium polyanthum leaf extract on blood glucose, malondialdehyde (MDA) and insulin levels in diabetic rat models through a systematic review. This review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Literature searches were performed in PubMed, Scopus, ScienceDirect, and Google Scholar. Included studies were experimental in vivo studies using diabetic rat models that assessed the effects of Syzygium polyanthum extract on blood glucose, insulin, and/or MDA levels. Risk of bias was evaluated using the CAMARADES tool. The results showed that administration of Syzygium polyanthum extract at doses of 250–500 mg/kg body weight consistently reduced blood glucose levels, accompanied by increased insulin levels and decreased MDA levels. These findings indicate that Syzygium polyanthum leaf extract has potential antidiabetic and antioxidant effects in animal models of diabetes
Improving Posyandu Cadres knowledge through stunting education and training on sea fish–based MPASI and PMT preparation in Darungan Village Ira Humairah; Patmawati Patmawati; Ema Qurnianingsih; Lina Lukitasari; St. Khaerunnisa; Fithriyah Cholifatul Ummah; Langgeng Agung Waskito; Citrawati Dyah Kencono Wungu; Imanta Alifia Oktavira; Novita Nur Ramadhani; Dede Sayyidatunnisa; Muhammad Hidayat; Gwenny Ichsan Prabowo
Buletin Pengabdian Bulletin of Community Services Vol. 6 No. 1 (2026): Bull. Community. Serv.
Publisher : LPPM Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/bulpen.v6i1.2

Abstract

Background and Aim: Stunting remains a major public health problem that affects child growth and development. Community-based nutritional interventions utilizing local food resources are important strategies to support stunting prevention. This community service activity aimed to improve the knowledge and skills of Posyandu cadres regarding stunting prevention through education and training on the preparation of sea fish–based MPASI and PMT in Darungan Village. Methods: The program was conducted using educational counseling, practical training, and mentoring activities for Posyandu cadres. Participants received materials on stunting prevention, balanced nutrition, and practical demonstrations of preparing sea fish–based MPASI and PMT. Knowledge improvement was evaluated using pre-test and post-test assessments. Results: The results showed a significant increase in participants’ knowledge regarding stunting prevention and balanced nutrition, with a p-value of 0.025 (p < 0.05). In addition, participants demonstrated improved practical skills in preparing nutritious sea fish–based complementary and supplementary foods for children. Conclusion: Education and training using locally available sea fish as nutritional resources effectively improved Posyandu cadres’ knowledge and practical skills in stunting prevention. This program has the potential to support sustainable community-based nutrition interventions and contribute to achieving Sustainable Development Goal (SDG) 3, namely Good Health and Well-being.
Co-Authors , Atika . Kholik Adi, Ginanjar Sasmito Amin, Indah Binti Mohd Amin, Mochammad Anggraeni Dyah Kumalasari Anggraeni, Zuhrotul Eka Yulis Atika Ayesie Natasha Zulka Bakhtiar, Arief Bayu Satria Wiratama Dede Sayyidatunnisa Elvaretta, Clarissa Ely Rahmatika Nugrahani Ely Rahmatika Nugrahani, Ely Rahmatika Fithriyah Cholifatul Ummah Ginanjar Sasmito Adi Gwenny IP Hamzah, Arshq Mirza Harianto Notopuro Hendri Susilo HERAWATI, LILIK Humairah, Ira I Putu Bayu Agus Saputra Imanta Alifia Oktavira Indiarto, Muhammad Irfan Indri Safitri Indri Safitri, Indri Irwadi, Irfiansyah Kadek Rachmawati Khaerunnisa, Siti Kumalasari, Anggraeni Dyah Leonita Anniwati Maftuchah Maftuchah Maria Inge Lusida Muhammad Hidayat Muhammad Hidayat Muhammad Irfan Indiarto Nadya Husni Ningrum, Astika Gita Novita Nur Ramadhani Othman, Zulhabri Palupi, Dian Eka Roro Patmawati Patmawati Prabowo, Gwenny Ichsan Pradana, Munawer Qurnianingsih, Ema Raden Argarini Retno Handajani Reza Arta BN Riwu, Katty Hendriana Priscilia Rusyda, Aqila sabila Santoso, Brian Nathaniel Setyawati, Dewi Siti Khaerunnisa Siti Khaerunnisa Siti Khaerunnisa M.Si SOETJIPTO . St. Khaerunnisa Suhartati Suhartati Suhartati Susi Wahyuning Asih Susi Wahyuning Asih, Susi Wahyuning Sutji Kuswarini Suwandito Suwandito Suwandito, Suwandito Syafa'ah, Irmi Syafa’ah, Irmi Ummah, Fithriyah Cholifatul Ummah, Fithriyah Cholifatul Ummah Waskito, Langgeng Agung Wungu, Citrawati Dyah Kencono Yasan, Yanna Debby Restifanny Zuhrotul Eka Yulis Anggraeni Zulhabri Othman Zulka, Ayesie Natasha