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Prevalensi Skabies pada Warga Binaan di Lembaga Pemasyarakatan Kelas IIA Tuminting Manado Raul C. Zachawerus; Nurdjannah J. Niode; Marlyn. G. Kapantow
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.53598

Abstract

Abstract: Scabies is a contagious skin disease caused by the mite Sarcoptes scabiei var, hominis. The prevalence of scabies in Indonesia in 2016 is estimated at 4.6-12.9% of the 261.6 million population. Scabies ranks 3rd out of the 12 most common skin infections. This study aimed to determine the prevalence of scabies among inmates in Lembaga Pemasyarakatan kelas IIA Tuminting Manado (correctional insitution). This was a quantitative and descriptive study with a cross sectional design using The DeSkab (Deteksi Skabies) questionnaire. The results showed that 86 inmates out of a total of 190 inmates were detected of having scabies (45.3%) dominated by age 25-44 years (51.2%), middle education (76.7%), and unqualified occupancy density (100%). The most common distributions of lesions were between fingers (30.7%), followed by front part of wrist (20.2%), and elbow (13.5%). Cardinal signs of scabies were itching worse at night (98.8%), followed by lesions (86.1%), and itching complained by roommates (70.9%). In conclusion, the prevalence of scabies in Lembaga Pemasyarakatan kelas IIA Tuminting Manado is 45.3%. Inmates with detected scabies are dominated by age 25-44 years, middle education, unqualified occupancy density, distribution of lesion between fingers, and cardinal sign as itching worse at night. Keywords: scabies; correctional institution; inmates    Abstrak: Skabies merupakan penyakit kulit menular yang diakibatkan oleh tungau Sarcoptes scabiei var, hominis. Skabies menempati peringkat 3 dari 12 penyakit infeksi kulit tersering. Penelitian ini bertujuan untuk mengetahui prevalensi skabies pada warga binaan di Lembaga Pemasyarakatan kelas IIA Tuminting Manado. Jenis penelitian ialah deskriptif kuantitatif dengan desain potong lintang dan menggunakan kuesioner DeSkab (Deteksi Skabies). Hasil penelitian mendapatkan 86 warga binaan dari total 190 warga binaan yang terdeteksi skabies (45,3%), didominasi oleh usia 25-44 tahun (51,2%), tingkat pendidikan menengah (76,7%), dan kepadatan hunian yang tidak memenuhi syarat (100%). Sebaran lokasi lesi yang terbanyak ialah sela jari tangan (30,7%), diikuti pergelangan tangan depan (20,2%), dan siku luar (13,5%). Tanda kardinal skabies yang tersering muncul ialah keluhan gatal pada malam hari (98,8%), diikuti adanya bintil/lecet/borok (86,1%), dan keluhan gatal pada orang lain (sekamar) (70,9%). Simpulan penelitian ini ialah prevalensi skabies pada warga binaan Lembaga Pemasyarakatan Kelas IIA Tuminting Manado sebesar 45,3%. Warga binaan terdeteksi skabies didominasi oleh usia 25-44 tahun, tingkat pendidikan menengah, kepadatan hunian yang tidak memenuhi syarat, sebaran lokasi lesi di sela jari tangan, dan tanda kardinal skabies keluhan gatal pada malam hari. Kata kunci: skabies; lembaga pemasyarakatan; warga binaan
Tingkat Pengetahuan Penggunaan Kosmetik pada Akne Vulgaris serta Sikap dan Perilaku Penggunaan Kosmetik pada Mahasiswa Fakultas Kedokteran Sabrinna R. N. Hanumningtyas; Ferra O. Mawu; Nurdjannah J. Niode
Medical Scope Journal Vol. 6 No. 2 (2024): Medical Scope Journal
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/msj.v6i2.53657

Abstract

Abstract: Some cosmetics contain risky ingredients for the skin, especially for those with sensitive skin or acne. This study aimed to obtain the level of knowledge, attitude, and behavior towards cosmetics use in acne vulgaris (AV) among medical students. This was a descriptive categorial with a cross sectional design using primary data in the form of questionnaires. Respondents were students of Medical Faculty, Universitas Sam Ratulangi, Manado. The results showed that the level of knowledge of the cosmetics use in AV was in the moderate category (53.6%). The attitude of cosmetic use in the poor category was 100%. The behaviors of cosmetic use were, as follows: face cleaning twice a day (71.5%), using one type of facial cleanser (43.6%), using one facial cleansing device (71.5%), always using facial cream (36.9%), always using sunscreen (46.9%), and female respondents who used solid powder (41.8%). In conclusion, the level of knowledge of medical students at Universitas Sam Ratulangi was in moderate category, meanwhile the attitude was in poor category. Furthermore, the majority of students exhibited the behavior of cleansing their faces twice daily, using a singular type of facial cleanser and cleansing device. Additionally, most students consistently applied facial cream and sunscreen, while a significant portion of female respondents using compact powder. Keywords: level of knowledge; attitude; behavior; cosmetics; medical students    Abstrak: Beberapa jenis kosmetik mengandung bahan berisiko bagi kulit, terutama untuk yang berkulit sensitif atau berjerawat. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan penggunaan kosmetik pada acne vulgaris (AV) serta sikap dan perilaku penggunaan kosmetik pada mahasiswa Fakultas Kedokteran (FK). Jenis penelitian ialah deskriptif kategorik dengan desain potong lintang menggunakan kuesioner. Responden penelitian ialah mahasiswa FK Universitas Sam Ratulangi (Unsrat). Hasil penelitian memperlihatkan tingkat pengetahuan penggunaan kosmetik pada AV berada dalam kategori cukup sebesar 53,6%. Sikap penggunaan kosmetik responden berada dalam kategori kurang sebesar 100%. Perilaku penggunaan kosmetik responden dalam membersihkan wajah 2x/hari (71,5%), menggunakan satu jenis pembersih wajah (43,6%), menggunakan satu perangkat pembersih wajah (71,5%), selalu menggunakan krim wajah (36,9%), selalu menggunakan tabir surya (46,9%), dan responden perempuan yang menggunakan bedak padat (41,8%). Simpulan penelitian ini ialah tingkat pengetahuan mahasiswa FK Unsrat ialah cukup, sikap mahasiswa dalam penggunaan kosmetik ialah kurang, dan perilaku mahasiswa mayoritas membersihkan wajah dua kali sehari, menggunakan satu jenis pembersih dan perangkat pembersih wajah. Sebagian besar mahasiswa selalu menggunakan krim wajah dan tabir surya, serta sebagian besar responden perempuan menggunakan bedak padat.   Kata kunci:  tingkat pengetahuan; sikap; perilaku; kosmetik; mahasiswa fakultas kedokteran
Evaluation of Gradient Boosted Classifier in Atopic Dermatitis Severity Score Classification Suhendra, Rivansyah; Suryadi, Suryadi; Husdayanti, Noviana; Maulana, Aga; Noviandy, Teuku Rizky; Sasmita, Novi Reandy; Subianto, Muhammad; Earlia, Nanda; Niode, Nurdjannah Jane; Idroes, Rinaldi
Heca Journal of Applied Sciences Vol. 1 No. 2 (2023): October 2023
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/hjas.v1i2.85

Abstract

This study investigates the application of the Gradient Boosting machine learning technique to enhance the classification of Atopic Dermatitis (AD) skin disease images, reducing the potential for manual classification errors. AD, also known as eczema, is a common and chronic inflammatory skin condition characterized by pruritus (itching), erythema (redness), and often lichenification (thickening of the skin). AD affects individuals of all ages and significantly impacts their quality of life. Accurate and efficient diagnostic tools are crucial for the timely management of AD. To address this need, our research encompasses a multi-step approach involving data preprocessing, feature extraction using various color spaces and evaluating classification outcomes through Gradient Boosting. The results demonstrate an accuracy of 93.14%. This study contributes to the field of dermatology by providing a robust and reliable tool to support dermatologists in identifying AD skin disease, facilitating timely intervention and improved patient care.
Evaluation of atopic dermatitis severity using artificial intelligence Maulana, Aga; Noviandy, Teuku R.; Suhendra, Rivansyah; Earlia, Nanda; Bulqiah, Mikyal; Idroes, Ghazi M.; Niode, Nurdjannah J.; Sofyan, Hizir; Subianto, Muhammad; Idroes, Rinaldi
Narra J Vol. 3 No. 3 (2023): December 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i3.511

Abstract

Atopic dermatitis is a prevalent and persistent chronic inflammatory skin disorder that poses significant challenges when it comes to accurately assessing its severity. The aim of this study was to evaluate deep learning models for automated atopic dermatitis severity scoring using a dataset of Aceh ethnicity individuals in Indonesia. The dataset of clinical images was collected from 250 patients at Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia and labeled by dermatologists as mild, moderate, severe, or none. Five pre-trained convolutional neural networks (CNN) architectures were evaluated: ResNet50, VGGNet19, MobileNetV3, MnasNet, and EfficientNetB0. The evaluation metrics, including accuracy, precision, sensitivity, specificity, and F1-score, were employed to assess the models. Among the models, ResNet50 emerged as the most proficient, demonstrating an accuracy of 89.8%, precision of 90.00%, sensitivity of 89.80%, specificity of 96.60%, and an F1-score of 89.85%. These results highlight the potential of incorporating advanced, data-driven models into the field of dermatology. These models can serve as invaluable tools to assist dermatologists in making early and precise assessments of atopic dermatitis severity and therefore improve patient care and outcomes.
Secondary Syphilis Reinfection with Suspected Asymptomatic Neurosyphilis Mahono, Charles Kurnia; Niode, Nurdjannah Jane
Indonesian Journal of Case Reports Vol. 1 No. 2 (2023): December 2023
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v1i2.119

Abstract

Syphilis, a sexually transmitted disease caused by Treponema pallidum, poses a significant global health threat, with an annual incidence of around 12 million cases, predominantly affecting individuals aged 15-49. Reinfection occurs in 11 out of 120 patients, underscoring the importance of effective management. If untreated, 4-9% of cases may progress to early neurosyphilis, often presenting asymptomatically. We present the case of a 22-year-old male with reddish-brown patches on the face, palms, and soles, along with erythematous papules on the genital region, following a history of recent promiscuity. Physical examination revealed distinctive manifestations, including nickels and dimes on the face, syphilitic roseola, Biett's collarette on the palmoplantar region, and erythematous papules-plaques on the scrotal and penile areas. The VDRL test indicated a titer of 1:32, TPHA test >1:5120, and a non-reactive HIV rapid test. Initiating treatment with a single intramuscular injection of benzyl benzathine penicillin G (2.4 million IU) resulted in successful symptom resolution, accompanied by a four-fold decrease in VDRL titer to 1:8 by the third month. However, a subsequent increase to 1:32, following sexual intercourse in the sixth month, indicated reinfection and raised suspicions of asymptomatic neurosyphilis. The patient received oral doxycycline (100 mg twice daily) for 30 days. Unfortunately, treatment success could not be determined as the patient was lost to follow-up. This case report highlights that elevated VDRL titers signify reinfection, treatment failure, or neurosyphilis. Asymptomatic reinfection is common due to lead-time bias and partial immunity, especially with multiple episodes of syphilis. Early neurosyphilis may coexist with primary or secondary syphilis and is frequently asymptomatic. Continued efforts in monitoring and treatment adherence are crucial for effective syphilis management on a global scale.
FAKTOR - FAKTOR RISIKO PENYAKIT TIDAK MENULAR PADA MAHASISWA PROGRAM STUDI PENDIDIKAN DOKTER GIGI UNIVERSITAS SAM RATULANGI Wijaya, Natalya; Manampiring, Aaltje Ellen; Niode, Nurdjannah Jane
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 3 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i3.36285

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Peningkatan prevalensi Penyakit Tidak Menular (PTM) seperti penyakit kardiovaskular, diabetes, kanker di kalangan dewasa muda, terutama mahasiswa, menjadi perhatian serius mengingat perilaku gaya hidup tidak sehat yang sering terjadi pada kelompok ini. Penelitian ini bertujuan untuk mengidentifikasi faktor risiko perilaku yang berkontribusi terhadap perkembangan PTM pada mahasiswa Program Studi Pendidikan Dokter Gigi Fakultas Kedokteran Universitas Sam Ratulangi. Fokus penelitian ini meliputi kebiasaan merokok, konsumsi alkohol, kurangnya aktivitas fisik, serta pola makan tidak sehat. Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan pengambilan data menggunakan metode Focus Group Discussion (FGD) yang melibatkan 24 mahasiswa, terdiri dari 12 mahasiswa pre-klinik dan 12 mahasiswa klinik. Responden dipilih menggunakan teknik purposive sampling. Data dianalisis menggunakan pendekatan tematik untuk mengidentifikasi pola-pola perilaku berisiko yang berkontribusi terhadap PTM. Hasil penelitian menunjukkan bahwa 16,6% responden adalah perokok aktif, dengan sebagian besar merokok sebagai bagian dari interaksi sosial. Konsumsi alkohol dilaporkan oleh beberapa mahasiswa, meskipun dalam frekuensi yang rendah, terutama dalam konteks kegiatan sosial. Aktivitas fisik mahasiswa sangat kurang, mayoritas responden tidak mencapai rekomendasi WHO untuk berolahraga setidaknya 150 menit per minggu. Sebagian besar responden juga menunjukkan pola makan yang tidak sehat, dengan kecenderungan konsumsi makanan cepat saji dan rendahnya asupan buah serta sayuran. Kesimpulan  penelitian ini faktor lingkungan memiliki kontribusi besar terhadap praktik prilaku yang dapat berisiko terjadinya penyakit tidak menular. Kemampuan manajemen stres, waktu, ekonomi, akses terhadap fasilitas olahraga yang tidak adekuat merupakan faktor penunjang praktik perilaku yang dapat berisiko pada terjadinya penyakit tidak menular.  Perlunya intervensi institusi, seperti promosi kesehatan yang lebih intensif, peningkatan fasilitas olahraga, dan penyediaan opsi makanan sehat di kampus, untuk mengurangi prevalensi perilaku berisiko di kalangan mahasiswa.
Mechanistic insights into the anticancer, anti-inflammatory, and antioxidant effects of yellowfin tuna collagen peptides using network pharmacology Kairupan, Tara S.; Kapantow, Nova H.; Tallei, Trina E.; Niode, Nurdjannah J.; Sanggelorang, Yulianty; Rotty, Linda WA.; Wungouw, Herlina IS.; Kawengian, Shirley ES.; Fatimawali, Fatimawali; Maulydia, Nur B.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1885

Abstract

Marine-derived collagen peptides have been acknowledged for their therapeutic potential, especially in cancer therapy and inflammation management. The aim of this study was to investigate the molecular mechanisms that contribute to the anticancer, anti-inflammatory and antioxidant properties of yellowfin tuna collagen peptides (YFTCP) utilizing a network pharmacology approach. The YFTCP was extracted from the bones of yellowfin tuna (Thunnus albacares) and subsequently hydrolyzed with trypsin. Seventeen peptides were discovered using liquid chromatography in conjunction with high-resolution mass spectrometry (LC-HRMS). A network pharmacology method was utilized to investigate the interactions between the discovered peptides and their biological targets. Additionally, gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed to identify pertinent biological pathways involved in the anticancer, antioxidant, and anti-inflammatory effects of these peptides. GO analysis revealed key associations between YFTCP and critical cancer- and inflammation-related genes encoding proteins such as CCND1, SRC, AKT1, IL-1β, TNF, and PPARG, which exhibited significant interactions. These proteins are essential for the regulation of the cell cycle, the development of tumors, and the response to inflammatory stimuli. The KEGG analysis also revealed that YFTCP was involved in a number of critical pathways, such as endocrine resistance, cancer pathways, Kaposi sarcoma-associated herpesvirus infection, proteoglycans in cancer, and human cytomegalovirus infection. These findings highlight the potential use of YFTCP as a multifaceted therapeutic agent, indicating their role in regulating important biological pathways associated with cancer development and inflammation. This study provides new valuable insights into the pharmacological properties of YFTCP, paving the way for future studies and drug development focused on these bioactive peptides.
Vaksin Tungau Debu Rumah: Terobosan Baru untuk Mengatasi Tantangan Dermatitis Atopik Adji, Aryani; Niode, Nurdjannah J.; Wijaya, Lorettha; Putri, Devita
Bahasa Indonesia Vol 23 No 2 (2024): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v23i2.3830

Abstract

Pendahuluan: Dermatitis atopik (DA) adalah penyakit inflamasi kronis yang sering dikaitkan dengan alergen tungau debu rumah (TDR), terutama Dermatophagoides pteronyssinus. Penatalaksanaan saat ini belum memadai untuk memberikan perlindungan jangka panjang. Tujuan: Tinjauan ini bertujuan untuk mengeksplorasi potensi vaksin TDR sebagai terobosan baru dalam pengelolaan DA. Metode: Artikel ini disusun melalui telaah literatur dari jurnal, buku, dan dokumen relevan lainnya yang membahas DA, imunoterapi, dan vaksinasi terkait. Data dianalisis secara komprehensif untuk mendukung kesimpulan. Diskusi: Disfungsi sawar kulit dan respons imun yang dimediasi IgE adalah faktor utama dalam pathogenesis DA. Vaksinasi berbasis epitope TDR menawarkan peluang untuk pencegahan dengan efektivitas tinggi. Studi in sillico menunjukkan hasil menjanjikan, namun validasi lebih lanjut secara in vitro dan in vivo diperlukan. Pengembangan vaksin TDR multi-epitop dapat menjadi alternatif jangka panjang untuk DA. Simpulan: Vaksinasi TDR memiliki potensi besar sebagai strategi pencegahan primer untuk DA, namun penelitian lebih lanjut masih dibutuhkan untuk penerapan klinis.
Appraisal of Antioxidant Potential in Broccoli Microgreens under Different Drying Techniques Utilizing In Vitro and in Silico Methods Tallei, Trina Ekawati; Wungouw, Herlina Ineke Surjane; Kepel, Billy Johnson; Fatimawali, Fatimawali; Celik, Ismail; Niode, Nurdjannah Jane; Barasarathi , Jayanthi
Malacca Pharmaceutics Vol. 3 No. 1 (2025): March 2025
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/mp.v3i1.259

Abstract

Broccoli microgreens, rich in bioactive compounds, offer health benefits aligned with SDG 3: “Good Health and Well-Being.” Their antioxidants combat oxidative stress tied to chronic diseases, but drying can affect their activity. This study assessed the antioxidant capacities of fresh, microwave-dried, and air-fryer-dried broccoli microgreens using in vitro (DPPH assay) and in silico (molecular docking and dynamics) methods. The microgreens were cultivated under controlled conditions and dried using microwave and air-fryer techniques. Antioxidant activity was evaluated using the DPPH assay using ethanolic extracts. The bioactive compounds of fresh microgreens, detected through GC-MS, were analyzed in silico to evaluate their interactions with the target proteins CYP2C9 and NOX2. The findings revealed that air-fryer-dried microgreens demonstrated the highest DPPH activity, followed by fresh microgreens, while microwave-dried samples exhibited the lowest activity. GC-MS analysis of fresh samples revealed the presence of various compounds, including acids, ketones, sulfides, heterocycles, alcohols, esters, aromatic compounds, phthalate ester, and aldehydes. Molecular docking revealed strong interactions of certain compounds in fresh samples and CYP2C9 and NOX2, suggesting therapeutic potential against oxidative stress. Molecular dynamics simulations (MDS) showed stable binding for the CYP2C9-Methyl myristate complex, while the NOX-(Z)-1,2-Diphenylethene complex displayed weaker stability. In conclusion, broccoli microgreens show potential in mitigating oxidative stress, with air-fryer drying slightly enhancing their antioxidant activity. The antioxidant capacity of fresh microgreens is comparable to that of air-fryer-dried microgreens. In silico analyses demonstrate stable interactions between compounds in fresh microgreens and key proteins implicated in oxidative stress.
Dual anti-inflammatory and antimicrobial effects of stingless bee propolis on second-degree burns Manginstar, Christian O.; Tallei, Trina E.; Salaki, Christina L.; Niode, Nurdjannah J.; Jaya, Hendra K.
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.2359

Abstract

Propolis, a natural resinous product from stingless bees, is widely recognized for its anti-inflammatory and antimicrobial properties. However, its combined effects in addressing both inflammation and infection in second-degree burns have remained insufficiently explored. The study aimed to investigate the dual role of propolis in modulating inflammation and preventing bacterial infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa in a second-degree burn model. Propolis was collected from stingless bees in Gowa, South Sulawesi, Indonesia, and extracted using methanol. Second-degree burns were induced in male Rattus norvegicus, which were then divided into three groups: one treated with propolis, another silver sulfadiazine (positive control), and third with NaCl (negative control). After seven days of treatment, the expression of tumor necrosis factor-alpha (TNF-α) and vascular endothelial growth factor (VEGF) proteins in wound samples was analyzed using immunohistochemistry. The antimicrobial activity of the propolis extract was assessed using the disc diffusion assay, followed by minimum inhibitory concentration (MIC) testing. Network pharmacology analysis was also conducted to assess the anti-inflammatory activity of propolis. Results showed that propolis significantly reduced TNF-α expression and increased VEGF expression, which might enhance VEGF-mediated angiogenesis, leading to improved wound healing compared to controls. The antimicrobial tests demonstrated strong activity against MRSA and P. aeruginosa, with inhibition zones correlating with higher extract concentrations. The MIC value of the propolis extract was 198.66 µg/µL against MRSA and 212.06 µg/µL against P. aeruginosa. Network pharmacology analysis revealed key proteins, including Jun proto-oncogene (JUN), estrogen receptor 1 (ESR1), signal transducer and activator of transcription 3 (STAT3), and proto-oncogene tyrosine-protein kinase Src (SRC), involved in the regulation of TNF-α and VEGF, further supporting the synergistic effects of propolis. This study demonstrates that stingless bee propolis effectively promotes tissue regeneration and prevents infection in second-degree burns, highlighting its potential as an alternative to conventional treatments for wound care.
Co-Authors Adji, Aryani Alson . Sambonu, Alson . Andika, Agustinus B H. R. Kairupan Baguna, Tirsa Barasarathi , Jayanthi Celik, Ismail Christina Salaki Dwi H. Danardono, Dwi H. Dwi Y.F. Isa, Dwi Y.F. Earlia, Nanda Fatimawali . Feisy P. Matindas Ferra O. Mawu Ferra O. Mawu, Ferra O. Grace M. Kapantow Gunawan, Deni Gunawan, Ellen Herry E. J. Pandaleke Herry E.J. Pandaleke, Herry E.J. Herry E.J. Pandeleke, Herry E.J. Hizir Sofyan Husdayanti, Noviana Idroes, Ghazi M. Jaya, Hendra K. Jimmy Posangi Jootje M. L. Umboh Julian Jonathan, Julian Kairupan, Tara S. Kapantouw, Grace M. Kapantow, Nova Hellen Katuuk, Mario Esau Kawengian, Shirley ES. Kepel, Billy Johnson Korompis, Grace Esther Caroline Lorettha Wijaya Maharani, Ayu Mahono, Charles Kurnia Mamuaja, Enricco H. Manampiring, Aaltje Ellen Manginstar, Christian O. Marlyn G. Kapantow Marlyn. G. Kapantow Martha Marie Kaseke Marthen C. P. Wongkar, Marthen C. P. Maulana, Aga Maulydia, Nur B. Mawa, Melissa Abigael C Mellyanawati Mellyanawati Mikyal Bulqiah, Mikyal Momongan, Merry Vike Muhammad Subianto Nana N. Jayadi, Nana N. Niken Ernaningtyas, Niken Nova Hellen Kapantow Noviandy, Teuku R. Palimbong, Florencia Pandaleke, Thigita Pandjaitan, Marini C. Pieter L. Suling Pieter L. Suling Preisy G. I. Tampi, Preisy G. I. Pusung, Andreas V. Putri, Devita Raul C. Zachawerus Regina, Senduk Cindy Rinaldi Idroes Rotty, Linda WA. Rungkat, Timotius A. Runtuwene, Nadya Sabrinna R. N. Hanumningtyas Sasmita, Novi Reandy Siahaan, Romauli E. Silvia Nathalia Stella R. Nelwan Subadio, Nathanael Yngwie Christian Suhendra, Rivansyah Suryadi N. N. Tatura Suryadi Suryadi Susanti, Ratna I. Tendean, Lydia Estelina Naomi Tengke, Feniea Wulan Agaype Teuku Rizky Noviandy Thambas, Arthur Harris Thigita A. Pandaleke Trina E. Tallei, Trina E. TRINA EKAWATI TALLEI Tumilaar, Jibrando Turalaki, Grace Lendawati Amelia Umboh , Adrian Wibawa, Anthony S. Wijaya, Natalya Windy Patricya Stevani Lapian Wungouw, Herlina Ineke Surjane Wungouw, Herlina IS. Yulianty Sanggelorang