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All Journal ASPIRATOR Bestuur Bioedukasi: Jurnal Pendidikan Biologi BIOEDUSCIENCE Pharmasipha ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Abdi Insani Bubungan Tinggi: Jurnal Pengabdian Masyarakat Borneo Journal Of Pharmascientech Molekul: Jurnal Ilmiah Kimia Jurnal Ilmiah Global Farmasi Parapemikir Jurnal Ilmiah Farmasi Jurnal Abdimas Kesehatan ASPIRATOR - Journal of Vector-Borne Diseases Studies
Solikah Ana Estikomah
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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ANTIOXIDANT ACTIVITY TEST ON KEFIR WHEY WITH TURMERIC NATURAL DYE (Curcuma longa L.) Rohmah, Nilna Alfa; Estikomah, Solikah Ana; Kurniawan, Kurniawan; Budi Sawitri, Satwika
Jurnal Ilmiah Global Farmasi (JIGF) Vol. 2 No. 1 (2024): JIGF - Januari
Publisher : PC IAI Sragen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/jigf.v2i1.34

Abstract

Excess free radicals in a person's body to exceed the body's ability to manage them can cause a condition called oxidative stress. Oxidative stress is a condition of imbalance between the amount of free radicals present and the amount of antioxidants in the body. One of the Prevention of oxidative stress is by increasing the intake of antioxidants. During this time whey in most cheese companies just becomes a waste. As we know that the Whey contains high nutrients and has health benefits and contains antioxidants. The purpose of this study was to determine the use of cheese whey in kefir whey beverage processed products with turmeric natural dyes that are rich in antioxidants. This study was conducted by an experimental method consisting of 5 (five) stages, namely the first stage of making kefir whey drink with turmeric natural dyes. The second stage is testing pH, the third stage is testing water content, the fourth stage is antioxidant activity testing, the fifth is testing hedonic (liking). The results showed that the variant concentration of cheese whey significantly affect the water content, antioxidant activity and preferences (color, flavor, scent). But there is no real effect on the pH value because the average pH value is the same. Variable pH value, water content and hedonic (preference) does not affect antioxidant activity. So it can be concluded that kefir whey with turmeric natural dye has the potential as a drink that contains antioxidants that can reduce levels and can prevent oxidative stress.
Pengaruh Variasi Humektan pada Formulasi Hand Sanitizer serta Evaluasi Sediaan dan Daya Hambat terhadap Stapyhlococcus aureus Haryanto, Qurrah A'yuniyyah; Kurniawan, Kurniawan; Estikomah, Solikah Ana; Marfu'ah, Nurul
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 6 No. 2 (2022): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v6i2.7572

Abstract

The habits of the Indonesian people in carrying out hand hygiene activities are still very low with an average of only 12%. Along with the density of community activities, which consider hand washing a troublesome activity, it is also caused by the lack of clean water availability in the community. Therefore, there are hand sanitizer products that are practical without using water or commonly referred to as hand sanitizers. Hand sanitizer contains antiseptic substances that can kill germs on the palms due to the presence of alcohol (ethanol, propanol and isopropanol) and the phenol group (chlorhexidine and triclosan). Alcohol has the ability to inhibit bacterial growth, both against gram-positive and gram-negative bacteria, including MRSA (Methicilin Resistant of Staphylococcus aureus). The purpose of this study was to determine the effect of humectant variations on the evaluation of the preparation and the inhibition of Staphylococcus aureus bacteria. The results of the evaluation of the preparation of the hand sanitizer formulation are in accordance with the SNI No. 06-2588-1992, namely on the parameters of homogeneity, pH and dispersion. Meanwhile, the viscosity parameter is not in accordance with the standard. Variations in humectant concentration affect the evaluation of the preparation of the hand sanitizer gel formulation on the parameters of pH and dispersion. The formulation that had the greatest inhibition zone against Staphylococcus aureus was the formulation with the highest humectant concentration of propylene glycol, namely formulation 3 with an inhibitory power of 22.8 mm.
Formulasi sediaan deodoran spray ekstrak daun sirih merah (Piper crocatum Ruiz&Pav) dengan variasi alum (tawas) Kurniawan, Kurniawan; Kusumasary, Dhiyah Ayu; Estikomah, Solikah Ana; Marfu’ah, Nurul
Pharmasipha : Pharmaceutical Journal of Islamic Pharmacy Vol. 7 No. 2 (2023): September
Publisher : University Of Darussalam Gontor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/pharmasipha.v7i2.10665

Abstract

ABSTRACT One way to overcome body odor is by using deodorant. One of the herbal ingredients that can be used in deodorant formulations is Piper crocatum leaves. Piper crocatum leaves have numerous bioactive compounds as an antibacterial agent. Beside, the deodorants can be added with other ingredients for example, alum (KAl(SO4)2.12H2O) an antiperspirant. This study aims to determine the result of physical stability tests in deodorant spray formulations from Piper crocatum extract with variation of alum. Piper crocatum leaves were extracted using a maceration method with 70% ethanol solvent. The deodorant spray formulation uses Piper crocatum leaf extract with variation of alum at 0% (control), 10% (F-1), 20% (F-2) and 25% (F-3). The result were then tested for pH, organoleptic, homogeneity, spray power, dry time, and cloth effect. The result were then analyzed by comparing with the standard deodorant spray in the 1995 Pharmacopoeia and the 1998 Indonesian National Standard. The results showed that F-1 has the most standard test results covering organoleptic test results, homogeneity, pH, spray power, dry time and effect on fabrics. Keywords: alum, extract, deodorant spray, Piper crocatum,   ABSTRAK Salah satu cara untuk mengatasi bau badan adalah dengan cara menggunakan deodoran. Salah satu bahan herbal yang dapat digunakan dalam formulasi deodoran adalah daun sirih merah. Daun sirih merah memiliki senyawa yang memiliki kemampuan antibakteri. Selain bahan aktif, deodoran dapat ditambahi dengan bahan lain misalnya aluminium kalium sulfat yang berfungsi debagai antiperspiran. Penelitian ini bertujuan untuk mengetahui hasil uji stabilitas fisik dalam formulasi deodran spray dari ekstrak sirih merah dengan variasi alumunium kalium sulfat. Daun sirih merah diekstrak menggunakan metode maserasi dengan pelarut etanol 70%. Formulasi deodorant spray menggunakan ekstrak daun siirh merah dengan variasi aluminium kalium sulfat sebesar 0% (control), 10% (F-1), 20% (F-2) dan 25% (F-3). Hasil sediaan kemudian di uji pH, organoleptik, homogenitas, daya semprot, waktu kering, dan efek kain. Hasil pengamatan dianalisis dengan cara membandingkan dengan standar deodoran spray yang ada di Farmakope 1995 dan Standar Nasional Indonesia 1998. Hasil penelitian menunjukkan bahwa sediaan F-1 adalah sediaan yang memiliki hasil uji paling memenuhi standar meliputi hasil uji organoleptic, homogenitas, pH, daya semprot, waktu kering dan efek terhadap kain.     Kata kunci : alum, deodoran spray, ekstrak, sirih merah
Antimicrobial Activity of Natural Solid Soap with a Combination of Liquid Cheese Waste, Turmeric (Curcuma longa), and Dragon Fruit (Hylocereus polyrhizus) Peel Estikomah, Solikah Ana; Suranto, Suranto; Susilowati, Ari; Masykuri, Mohammad
Molekul Vol 18 No 3 (2023)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2023.18.3.8039

Abstract

Yoghurt whey is a product from fermented cheese liquid waste. Yoghurt cheese liquid waste has been known to contain lactoferrin. Lactoferrin functions as an antimicrobial. yoghurt made from whey has not been widely utilized as a solid soap ingredient. This research focuses on producing solid natural soap made of yoghurt whey with added natural dye turmeric and dragon fruit peel, soap quality testing, and analysis of the soap's antibacterial activity toward Staphylococcus aureus. The solid soap was processed through the saponification reaction between palm oil, coconut oil, zaitun oil, and canola oil with sodium hydroxide. Variations of yogurt whey used in this study yoghurt 25%,75%,100% whey) was added natural dye (turmeric and dragon fruit peel). The quality test was done by determining free alkali, water content, pH, and foam height. Antibacterial activity test using the well diffusion method. The result shows that the quality test yoghurt soap meets with INS (Indonesia National Standard) 2016, for all the criteria. Performs inhibition against bacteria Staphylococcus aureus. Yoghurt whey is potently used as an antibacterial agent in the manufacture of natural solid soap.
FORMULASI ORAL DISINTEGRATING TABLET (ODT) EKSTRAK LABU AIR (Lagenaria siceraria (Molina) Standl) KOMBINASI SUPERDISINTEGRANT CROSPOVIDONE® dan SODIUM STARCH GLYCOLATE® Kurniawan, K; Tsalsabila, Zaviera; Estikomah, Solikah Ana; Al Hasanah, Fauziyyah
Jurnal Ilmiah Global Farmasi (JIGF) Vol. 2 No. 3 (2024): JIGF - September
Publisher : PC IAI Sragen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/jigf.v2i3.77

Abstract

Sediaan obat mengalami perubahan yang dinamis, seiring perkembangan teknologi. Salah satunya sedaiaan ODT, keuntungan utama ODT adalah kemudahan pemakaian obat karena dapat ditelan tanpa membutuhkan air. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh kombinasi superdisintegrant crospovidone dan sodium starch glycolate terhadap mutu fisik sediaan ODT ekstrak labu air dan pada konsentrasi berapakah kombinasi kedua superdisintegrant tersebut yang mampu menghasilkan ODT ekstrak labu air dengan waktu hancur yang cepat. Buah labu air diekstraksi menggunakan metode soxhletasi dengan pelarut methanol 70%. Ekstrak kering buah labu air dibuat dengan menggunakan aerosil. Sediaan ODT ekstrak labu air dilakukan dengan metode kempa langsung dengan berbagai kombinasi bahan. Variasi kombinasi superdisintegrant crospovidone dan sodium starch glycolate yang digunakan yaitu 6:2, 5:3, dan 3:5. Dilakukan pengujian terhadap sifat fisiknya meliputi waktu alir dan sudut diam. Pencetakan tablet dilakukan dengan mesin cetak tablet single punch dengan bobot tiap tablet 500 mg. Pengujian sifat fisik tablet meliputi keseragaman bobot, kekerasan, kerapuhan, pembasahan, waktu hancur dan tanggap rasa. Data dianalisis dengan pendekatan teoritis dan statistik dengan menggunakan uji One-Way Anova dilanjutjan dengan uji Post Hoc metode Tukey HSD. Hasil penelitian menunjukkan bahwa ekstrak buah labu air dapat dibuat sediaan ODT, formula tablet ekstrak labu air kombinasi superdisintegrant crospovidone dan sodium starch glycolate dengan perbandingan 6:2, 5:3 dan 3:5 dapat menghasilkan tablet yang memenuhi persyaratan sifat alir, sudut diam, keseragaman ukuran, kekerasan tablet, waktu pembasahan dan waktu hancur tablet. Sementara parameter persyaratan ODT yang paling baik pada formulasi I. perbedaan variasi kombinasi superdisintegrant crospovidone dan sodium starch glycolate berpengaruh terhadap kualitas mutu fisik tablet ekstrak buah labu air (Lagenaria siceraria (Molina) Standl). Kombinasi superdisintegrant crospovidone(6%) dan sodium starch glycolate (2%) menghasilkan waktu hancur yang cepat dibandingkan dengan formulasi yang lainnya, yaitu 22,87 detik.
Efektivitas Peel-Off Face Mask Ekstrak Biji Pinang (Areca carechu L) Dalam Menghambat Pertumbuhan Bakteri Staphylococcus epidermidis Fitrian, Ahyana; Sawitri, Satwika Budi; Estikomah, Solikah Ana; Fauziyyah, Khansa
Parapemikir : Jurnal Ilmiah Farmasi Vol 14, No 2 (2025): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v14i2.8667

Abstract

Jerawat merupakan gangguan kulit yang sering muncul di area wajah, leher, dada, dan punggung. Pengobatan jerawat umumnya dilakukan dengan penggunaan antibiotik untuk mengurangi peradangan dan membunuh bakteri, tetapi penggunaan antibiotik yang terlalu sering dapat menyebabkan resistensi bakteri, sehingga diperlukan alternatif lain dengan menggunakan bahan herbal misalnya biji pinang yang mengandung senyawa flavonoid, alkaloid, tannin, dan saponin sebagai antibakteri yang dibuat dalam bentuk sediaan masker gel peel-off. Penelitian ini bertujuan untuk membuat dan mengevaluasi mutu sediaan masker gel peel-off ekstrak biji pinang serta uji daya hambat terhadap pertumbuhan bakteri Staphylococcus epidermidis. Penelitian ini merupakan penelitian eksperimental dengan membuat masker gel peel-off dengan variasi konsentrasi ekstrak biji pinang F0 (0%), F1 (2,5%), F2 (5%), F3 (7,5%). Uji antibakteri Staphylococcus epidermidis menggunakan metode difusi cakram. Data hasil evaluasi mutu sediaan dianalisis dengan membandingkan standar SNI sedangkan hasil uji aktivitas antibakteri dianalisis menggunakan One Way ANOVA dengan taraf signifikansi 95%. Hasil penelitian ini menunjukkan bahwa hasil uji organoleptic berwarna merah, sediaan homogen, pH 6,84-7,47, viskositas 2772,5-3098,9 cPs, daya sebar 4,36-5,32 cm, waktu mengering 21 menit 61 detik-27 menit 9 detik. Sediaan masker gel peel-off memiliki kemampuan antibakteri Staphylococcus epidermidis dengan daya hambat paling besar yaitu konsentrasi ekstrak 7,5% (F 3) dengan rata-rata zona hambat sebesar 13,83 mm.
PENGARUH VARIASI KONSENTRASI EKSTRAK DAUN MELINJO (Gnetum gnemon L.) DALAM MENGHAMBAT PERTUMBUHAN Staphylococcus aureus PADA SEDIAAN SALEP Sawitri, Satwika Budi; Kurniawan; Estikomah, Solikah Ana; Zahron, Maulida Lutfia
Jurnal Ilmiah Global Farmasi (JIGF) Vol. 3 No. 2 (2025): JIGF - Mei
Publisher : PC IAI Sragen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21111/jigf.v3i2.96

Abstract

Penyakit infeksi pada kulit seperti bisul, kudis, panu merupakan beberapa contoh penyakit kulit yang masih menjadi masalah kesehatan di Indonesia. Salah satu bakteri penyebab infeksi kulit yaitu Stapylococcus aureus. Daun melinjo (Gnetum gnemon L.) merupakan salah satu tanaman yang memiliki efek antibakteri. Tujuan penelitian ini adalah membuat formulasi sediaan salep ekstrak etanol daun melinjo (Gnetum gnemon L.) dengan melihat karakteristik salep dengan variasi konsentrasi ekstrak daun melinjo, mengetahui adanya potensi aktivitas antibakteri terhadap bakteri Staphylococcus aureus, serta mengetahui pengaruh konsentrasi ekstrak daun melinjo terhadap mutu fisik sediaan dan aktivitas antibakteri Staphylococcus aureus dalam sediaan salep. Penelitian ini merupakan penelitian eksperimental di laboratorium dengan pembuatan variasi konsentrasi ekstrak daun melinjo dengan cara maserasi menggunakan pelarut etanol 96% dengan formula basis vaseline album dan adeps lanae. Formula dibuat dalam 4 konsentrasi yang berbeda yaitu 15%, 25%, 35%, dan 45%. Selanjutnya dilakukan evaluasi sediaan salep berupa uji organoleptik, homogenitas, pH, daya sebar, serta uji aktivitas antibakteri. Hasil penelitian menunjukkan bahwa salep ekstrak daun melinjo (Gnetum gnemon L.) memiliki karakteristik salep yang baik meliputi uji organoleptis, uji homogenitas, uji pH, terkecuali untuk uji daya sebar, kemudian salep ekstrak daun melinjo memiliki potensi terhadap bakteri Staphylococcus aureus dengan hasil kategori respon hambat antibakteri yang lemah hingga kuat, serta variasi konsentrasi ekstrak daun melinjo dapat berpengaruh terhadap mutu fisik sediaan dan aktivitas antibakteri Staphylococcus aureus dalam sediaan salep.
Formulation and Inhibiting Activity of Paper Soap Yogurt Whey with Natural Dye of Hylocereus polyrhizus Skin Against Staphylococcus aureus Estikomah, Solikah Ana; Kautsar, Alfia Manda Putri; Widyaratna, Indri; Muryani, Eni; Ardiyanti, Dwi
BIOEDUSCIENCE Vol 9 No 2 (2025): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/18330

Abstract

Background: Yogurt is a product of fermented cheese liquid waste, which is known to contain lactoferrin, which functions as an antimicrobial. Whey-based yogurt has not been used as an ingredient in making paper soap. This study aims to determine the formula and evaluation of paper soap with the addition of whey yogurt with natural dyes from Hylocereus polyrhizus skin. Methods: This study is an experimental study. The preparation of liquid soap from whey yogurt with natural dyes from red dragon fruit skin (Hylocereus polyrhizus) was made into four whey yogurt formulas with concentrations of 25%, 50%, 75%, and 100%. Product quality includes organoleptic values, pH values, foam height, and alkali antibacterial activity test against Staphylococcus aureus using the Disk Disk method. Results: The results showed that all formulas of Paper soap whey yogurt with dragon fruit (Hylocereus polyrhizus) skin dye showed good physicochemical characteristics, pH 9.0–11 (ASTM 9-11 requirements), foam content 41.7–52.5, and free alkali content 0.02–0.04. Paper soap whey yogurt formula with dragon fruit (Hylocereus polyrhizus) skin dye produced an inhibitory power of 11.27–29.6, including the medium and strong categories. Conclusions: The best formula for Paper soap whey yogurt with dragon fruit (Hylocereus polyrhizus) skin dye is soap with raw material whey yogurt of 75% whey 25% fresh cow's milk. The results of this study indicate that Paper soap whey yogurt with dragon fruit (Hylocereus polyrhizus) skin dye has the potential as a natural antiseptic soap.
Formulation and Antibacterial Activity Test Liquid Soap with Eugenol Variant from Clove Leaf Oil (Eugenia aromaticum) Against Bacteria Staphylococcus aureus Estikomah, Solikah Ana; Azzahra , Adhinda Eugenia; Yulisa; Anugrah, Anugrah
BIOEDUSCIENCE Vol 9 No 2 (2025): BIOEDUSCIENCE
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/jbes/18513

Abstract

Background: The skin, as the largest organ of the body, hosts various types of bacteria. Excessive sebum production combined with bacterial infections can lead to skin issues such as irritation. Although chemical-based antiseptic soaps are effective, they may negatively impact both the environment and skin health. This has increased public interest in natural alternatives, such as cloves (Eugenia aromaticum), which contain eugenol an active compound with antiseptic, anti-inflammatory, and antibacterial properties. This study aimed to formulate a clove leaf oil-based liquid soap with varying concentrations of clove leaf oil: F1 (0%), F2 (4%), F3 (6%), and F4 (8%), and to evaluate its physical properties and antibacterial activity against Staphylococcus aureus. Methods: The disc diffusion method was employed to assess antibacterial activity. Results: The organoleptic test showed that the soap had a distinctive clove aroma, yellow color, and a liquid to thick homogeneous consistency. The pH values ranged from 8.97 to 9.14, foam stability ranged between 84.37% and 88.18%, viscosity ranged from 2510.72 to 6190.57 cP, and spreadability varied from 3.39 to 6.42 cm. Antibacterial testing revealed inhibition zones of 2.87 mm (F1), 7 mm (F2), 10 mm (F3), and 15.25 mm (F4), indicating increasing antibacterial activity with higher clove oil concentrations. Conclusions: The F2 formula was identified as the most balanced, with acceptable pH, optimal foam stability, moderate viscosity, and a 7 mm inhibition zone classified in the medium category. This study highlights the potential of clove leaf oil as a natural antibacterial agent in liquid soap formulations.
Aktivitas Larvasida Fraksi N-Heksan Ekstrak Etanol Daun Mengkudu (Morinda citrifolia. L) terhadap Larva Aedes sp.: Larvicide Activity of N-Hexane Fraction of Ethanolic Morinda citrifolia. L Leaves Extract on Aedes sp. Larvae Awaluddin, Rizki; Sholihatin, Binti; Marfu’ah, Nurul; Kurniawan; Estikomah, Solikah Ana
Aspirator Vol 13 No 2 (2021): Jurnal Aspirator Volume 13 Nomor 2 2021
Publisher : Perkumpulan Entomologi Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/asp.v13i2.4823

Abstract

Abstract. Aedes sp. is a vector of the dengue virus that causes Dengue Hemorrhagic Fever (DHF). Larvicides are the optimal method for controlling mosquito development. Temephos is a larvicidal agent of the organophosphate group which is reported to cause side effects and ecological hazards, as well as resistance based on reports in several country. This study aims to determine the larvicidal activity of the n-hexane fraction of Morinda citrifolia leaf ethanol extract on Aedes sp. The compound groups in the fraction were identified using TLC through UV light and spray reagents. There were six types of treatment including four concentration fractions (400, 600, 800, and 1000 ppm) as treatment, positive control (temephos 1%) and negative control 1% acetone solution. Twenty-five mosquito larvae of Aedes sp. tested for each treatment. Larval mortality was recorded and LC50 and LC99 values were analyzed using the probit. The results showed that the TLC test of the n-hexane fraction was positive for terpenoids, anthraquinones, phenols, tannins, and flavonoids. The results showed that the LC50 and LC99 values were 1040 ppm and 2439 ppm. Therefore, the n-hexane fraction of the ethanol extract had larvicidal activity on Aedes sp. with little toxicity. Abstrak. Aedes sp. merupakan vektor virus dengue penyebab Demam Berdarah Dengue (DBD). Larvisida merupakan metode yang optimal untuk mengendalikan perkembangan nyamuk. Temephos yang merupakan larvasida sintetik dapat menyebabkan resisten, efek samping dan bahaya ekologi. Kelimpahan agen hayati, efek toksik pada manusia yang minim, dan biodegradable menjadi tujuan utama perlunya pengembangan agen larvasida baru. Penelitian ini bertujuan untuk mengetahui aktivitas larvasida fraksi n-heksana ekstrak etanol daun mengkudu pada larva Aedes sp. Golongan senyawa pada fraksi diidentifikasi menggunakan KLT melalui pereaksi semprot. Terdapat enam jenis perlakuan diantaranya empat konsentrasi fraksi (400, 600, 800, dan 1000 ppm) sebagai perlakuan, kontrol positif (temephos 1%) dan kontrol negatif larutan aseton 1%. Dua puluh lima larva nyamuk Aedes sp. diujikan pada setiap perlakuan. Kematian larva dicatat dan nilai LC50 dan LC99 dianalisa menggunakan probit. Hasil penelitian menunjukkan bahwa uji KLT fraksi n-heksana positif mengandung terpenoid, antrakuinon, fenol, tanin, dan flavonoid. Hasil penelitian menunjukkan bahwa nilai LC50 dan LC99 adalah 1040 ppm dan 2439 ppm. Oleh karena itu, fraksi n-heksana dari ekstrak etanol memiliki aktivitas larvasida pada Aedes sp.
Co-Authors Aisyah Muthmainnah Aisyah Muthmainnah Al Hasanah, Fauziyyah Amal Fadholah Andi Sri Suriati Amal Annisa, Firstiyani Anugerah Suciati Anugrah, Anugrah Ardiyanti, Dwi ARI SUSILOWATI Asfy Nurany Awaluddin, Rizki Azzahra , Adhinda Eugenia Desta Astarina Saputri Toasa Desta Astarina Saputri Toasa Endang Endang Eni Muryani Fauziyyah, Khansa Fitrian, Ahyana Haryanto, Qurrah A'yuniyyah iaisragen, iaisragen Iftitahul Farihah Jiarti Kusbandiyah K Kurniawan K Kurniawan Kautsar, Alfia Manda Putri Kurniawan Kurniawan Kurniawan Kurniawan, Kurniawan Kusumasary, Dhiyah Ayu Lija Oktya Artanti Lilla Puji Lestari Maemunah Maemunah Marfu'ah, Nurul Marniati Marniati Mohammad Masykuri Muthiah Rabbaniyyah Nadia Iha Fatihah Nadia Saptarina Qurrah A'yuniyyah Haryanto Rizki Awaluddin Rizki Awaluddin Rizky Dila Khairunnisa Rohmah Madya Ayu Fitriana Rohmah, Nilna Alfa Ruskiah Octavia Satwika Budi Sawitri Sawitri, Satwika Budi Sholihatin, Binti Sri Fathiyah Safaatsih Sri Wahyuni Sri Wahyuni Sri Wahyuni Suranto Suranto Surya Amal Tsalsabila, Zaviera Vita Kaunia Wahyu Kumil Laila Widyaratna, Indri Widyaratna, Indriyanti Yulisa Zahron, Maulida Lutfia