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All Journal Jurnal Ilmiah Farmasi Pendidikan Biologi Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Current Biochemistry Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Keperawatan BSI Adi Widya : Jurnal Pengabdian Masyarakat Pharmasipha Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasi Indonesia INTEGRITAS : Jurnal Pengabdian Community Empowerment Jurnal Farmasi Proceeding Biology Education Conference Journal Prima Health Science Herbal Medicine Journal SWAGATI: Journal of Community Service Jurnal Sains dan Kesehatan Advance Sustainable Science, Engineering and Technology (ASSET) Sabar : Jurnal Pendidikan Agama Kristen dan Katolik Jurnal Hukum, Administrasi Publik dan Negara
Desi Purwaningsih
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Isolasi dan Uji Aktivitas Enzim Superoksida Dismutase (SOD) dari Bakteri Endofita Daun Tanaman Sukun (Artocarpus altilis) dengan Metode Water Soluble Tetrazolium Salt-1 (Wst-1) Fradine, Chossy; Wulandari, Destik; Purwaningsih, Desi
Herbal Medicine Journal Vol 8 No 2 (2025): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58996/hmj.v8i2.166

Abstract

Endophytic bacteria are bacteria that carry out symbiosis with host plants without causing disease without the host plant. Some endophytic bacteria found in plants are able to produce potential compounds as antioxidants by producing the enzyme SOD (Super Oxide Dismutase). This research aims to determine the results of endophytic bacterial fermentation from the leaves of the breadfruit plant (Artocarpus altilis). This research began with the identification of endophytic bacteria, then continued with the extraction of the SOD enzyme by adding PBS and centrifuging. Purification of the SOD enzyme was carried out using the ammonium sulfate precipitation method. Determination of total protein content using the Lowry method. SOD activity was measured by measuring the percent inhibition value using the Superoxide Dismutase Activity Assay Kit WST-1. The results of the research showed that the isolated bacteria had morphological characteristics in sequence from colony shape, color, size, elevation, edges, cell shape and Gram type for AL 4 bacteria Filamentous, white, medium, flat, Rhizoid, coccus, Gram +, citrate -, Catalase -, for IL11 bacteria Irregular, white, large, flat, entire, bacilli, and Gram +, citrate +, Catalase +. The extraction results from the crude extract produced a sediment weight of 2,915 g for AL4 and 1,653 g for IL11. The total protein content of the crude extract and 30% ammonium sulfate precipitation for isolate AL4 was 1.74 mg/mL and IL11 1.79 mg/ml. Then the percent inhibition value for isolate AL4 with a concentration of 20% was 64.02% and a concentration of 80% was 71.43%.
Integrasi Teknologi Digital dalam Pendidikan Agama Katolik : Tantangan dan Peluang Desi Purwaningsih; Tanzila Rahmi; Vicky Agus Arwanda
Sabar : Jurnal Pendidikan Agama Kristen dan Katolik Vol. 1 No. 1 (2024): Januari : Sabar : Jurnal Pendidikan Agama Kristen dan Katolik
Publisher : Asosiasi Riset Ilmu Pendidikan Agama dan Filsafat Indonesia

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Abstract

This article examines the potential for integrating digital technologies into the teaching of Catholic religious education. The study analyzes data from interviews with 20 Catholic religious teachers in secondary schools, which indicate that digital platforms can enhance teaching effectiveness and student engagement. However, challenges such as the digital divide and limited teacher training are also identified. This article provides practical guidance for overcoming these barriers and leveraging technology to support the mission of evangelization.
PEMBERIAN PENGETAHUAN MENJAGA KESEHATAN SAAT PUASA DENGAN GIZI SEIMBANG PADA IBU-IBU KADER POSYANDU DASAWISMA TANJUNG BARAT JAKARTA Kristina Simanjuntak, Kristina Simanjuntak; Heryani, Monalisa; Susantiningsih, Tiwuk; Purwaningsih, Desi; Juliana, Dara
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 8 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i8.3298-3304

Abstract

Berbuka puasa dengan tinggi karbohidrat, lipid, dan rendah serat maupun aktifitas fisik masih banyak terlihat di masyarakat yang menjalankannya. Efek yang ditimbulkannya adalah pembentukan dislipidemia yang berhubungan dengan gangguan jantung, hipertensi dan stroke. Puasa yang dilakukan dengan gizi seimbang dapat sebagai terapi untuk menjaga kesehatan. Tujuan Pengabdian Masyarakat ini adalah untuk memberikan pengetahuan dengan menjaga kesehatan selama puasa dengan gizi seimbang pada Ibu-ibu Kader Posyandu Dasawisma Rt 04 Tanjung Barat Jakarta. Metode pelaksanaan dengan mitra sebanyak 32 orang, memberikan penyuluhan pemberian pengetahuan menjaga kesehatan dengan gizi seimbang selama puasa dan pengisian quesionare sebelum dan sesudah pelaksanaan dan mengukur indeks massa tubuh (IMT),. Hasil menunjukkan IMT normal 31,25 % , kegemukan 46,88 % dan obesitas 21,87 %, dan  terdapat peningkatan pengetahuan tentang menjaga kesehatan selama puasa dengan gizi seimbang. Pemberian gizi seimbang pada saat puasa dapat meningkatkan kesehatan tubuh.
PEMBERIAN PENGETAHUAN MENJAGA KESEHATAN SAAT PUASA DENGAN GIZI SEIMBANG PADA IBU-IBU KADER POSYANDU DASAWISMA TANJUNG BARAT JAKARTA Simanjuntak, Kristina; Heryani, Monalisa; Susantiningsih, Tiwuk; Purwaningsih, Desi; Juliana, Dara
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 8 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i8.22794-63727-1

Abstract

Berbuka puasa dengan tinggi karbohidrat, lipid, dan rendah serat maupun aktifitas fisik masih banyak terlihat di masyarakat yang menjalankannya. Efek yang ditimbulkannya adalah pembentukan dislipidemia yang berhubungan dengan gangguan jantung, hipertensi dan stroke. Puasa yang dilakukan dengan gizi seimbang dapat sebagai terapi untuk menjaga kesehatan. Tujuan Pengabdian Masyarakat ini adalah untuk memberikan pengetahuan dengan menjaga kesehatan selama puasa dengan gizi seimbang pada Ibu-ibu Kader Posyandu Dasawisma Rt 04 Tanjung Barat Jakarta. Metode pelaksanaan dengan mitra sebanyak 32 orang, memberikan penyuluhan pemberian pengetahuan menjaga kesehatan dengan gizi seimbang selama puasa dan pengisian quesionare sebelum dan sesudah pelaksanaan dan mengukur indeks massa tubuh (IMT),. Hasil menunjukkan IMT normal 31,25 % , kegemukan 46,88 % dan obesitas 21,87 %, dan  terdapat peningkatan pengetahuan tentang menjaga kesehatan selama puasa dengan gizi seimbang. Pemberian gizi seimbang pada saat puasa dapat meningkatkan kesehatan tubuh
Formulasi Mouthwash Ekstrak Kulit Buah Nanas (Ananas comosus (L.) Merr) dengan Variasi Konsentrasi Gliserin sebagai Antibakteri Terhadap Streptococcus mutans ATCC 25175 Maharani, Novita; Aisiyah, Siti; Purwaningsih, Desi
Jurnal Farmasi (Journal of Pharmacy) Vol. 10 No. 2 (2021): Jurnal Farmasi (Journal of Pharmacy), October 2021
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Dental caries is a major disease in problems in the oral cavity especially in the teeth. The main cause of dental caries is the bacterium Streptococcus mutans which is a normal inhabitant of the oral cavity. Dental caries can be overcome using a mouthwash preparation containing antibacterial substances. Pineapple skin (Ananas comosus (L.) Merr) is one of the plants that contains substances that have antibacterial activity. The purpose of this study was to determine the physical quality and stability, and activity antibacterial of mouthwash pineapple skin extract. Pineapple skin extract was made in three mouthwash formulations using various concentrations of glycerin 5%, 10%, and 15%. Mouthwash were tested for physical quality and stability. Antibacterial activity test against Streptococcus mutans ATCC 25175 using the well method. The data obtained are presented in the form of tables and graphs processed with SPSS ver22 with the Paired T-Test method for testing viscosity and testing pH and ANOVA for measuring the diameter of the inhibition zone. The results showed that mouthwash preparations in all formulas with organoleptic physical qualities, viscosity, and stability produced good preparations, while in testing the physical quality of the pH did not meet the pH requirements of mouthwash preparations because of the influence of pineapple skin extract (Ananas comosus (L.) Merr). In testing the antibacterial activity of mouthwash, the diameter of the inhibition zone was obtained the base 0 mm; F1 11.08 mm; F2 13.08 mm; F3 15.08 mm; and control positive 16,75 mm.
OPTIMASI SEDIAAN GUMMY CANDY PARASETAMOL DENGAN VARIASI KONSENTRASI GELATIN DAN GLISERIN MENGGUNAKAN METODE SIMPLEX LATTICE DESIGN Nisa, Zaitun; Aisiyah, Siti; Purwaningsih, Desi
Jurnal Farmasi (Journal of Pharmacy) Vol. 11 No. 2 (2022): Jurnal Farmasi (Journal of Pharmacy), October 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/35yaf041

Abstract

Paracetamol gummy candy is a chewy candy that is composed of a mixture of sweeteners and hydrocolloid components containing paracetamol and is designed to crumble and melt on the tongue. This study aims to see the effect of variations in the concentration of gelatin and glycerin on the physical quality of paracetamol gummy candy preparations, and to determine the best concentration of gelatin and glycerin to obtain paracetamol gummy candy preparations with optimum physical properties. Preparation of the preparation using the casting method and using 8 formula designs from Design Expert Simplex Lattice Design with a ratio of gelatin and glycerin concentrations. The results of the physical quality test with the critical parameters of elasticity and moisture content were analyzed using the Simplex Lattice Design method. This method can be used to optimize the dosage formula in various variations in the amount of material composition, so as to produce the optimum formula with the expected physical characteristics. The results showed that gelatin had more effect on elasticity and glycerin had more effect on the water content of paracetamol gummy candy. The proportions of gelatin 998,723 mg and glycerin 51.277 mg resulted in the optimum formula with the best elasticity and water content of gummy candy paracetamol.
FORMULASI DAN UJI ANTIJAMUR Candida albicans KRIM EKSTRAK RIMPANG KENCUR (Kaempferiae galanga Linn.) DENGAN VARIASI ASAM STEARAT DAN TRIETANOLAMIN Irawan, Ira; Aisiyah, Siti; Purwaningsih, Desi
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/qzxj1g27

Abstract

The active compounds contained in the rhizome of kencur (Kaempferia galanga Linn.) include alkaloids, flavonoids, and tannins which are used as antifungals. This study aims to determine the effect of variations of stearic acid and triethanolamine on the physical quality and stability of cream preparations and their activity against Candida albicans ATCC 10231 and cream formulation formulas with the best physical quality and have antifungal activity. Kencur rhizome extract was obtained by maceration using 70% ethanol and formulated with an extract concentration of 12% and variations of stearic acid and triethanolamine with a ratio of (10:7, 13:5, 16:3). The formulation of the cream preparation was carried out by mixing the oil phase and the water phase and then physical quality was carried out including organoleptic tests, homogeneity, spreadability, adhesion, pH, viscosity, and Cycling test. This study used the disc diffusion method to determine antifungal activity and one way ANOVA for statistical analysis. The results showed that the diameter of the extract inhibition zone was 13.17 mm. Variations of stearic acid and triethanolamine affect the physical quality and antifungal activity of cream preparations. Cream preparations have antifungal activity against Candida albicans ATCC 10231. The best formula is formula 1 with variations of stearic acid : triethanolamine (10:7) which has the best physical quality, with an inhibition zone diameter of 13.00 mm which is strong in inhibiting fungal growth.
OPTIMASI GELLING AGENT PADA SEDIAAN GUMMY CANDY PARASETAMOL DENGAN METODE SIMPLEX LATTICE DESIGN Pradana, Arsitya; Aisiyah, Siti; Purwaningsih, Desi
Jurnal Farmasi (Journal of Pharmacy) Vol. 13 No. 1 (2024): Jurnal Farmasi (Journal of Pharmacy), April 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/p6a5c155

Abstract

The dosage form of paracetamol gummy candy has several advantages compared to other paracetamol preparations circulating in Indonesia, including fast onset, high bioavailability, pleasant taste, practical to use, easy to serve, acceptable to children, so can increase the impact of taking the drug. The aim of this research was to determine the effect of varying concentrations of gelatin and carrageenan on the elasticity, pH and air content of paracetamol gummy candy preparations and to determine the proportion of gelatin and carrageenan in the optimum formula using the Simplex Lattice Design method. The paracetamol gummy candy formula design from Design Expert SLD produced 8 runs with varying concentrations of gelatin and carrageenan. Critical parameters in determining the optimum formula include elasticity, pH and air content. Validation of the analytical method for testing the uniformity of paracetamol content of gummy candy using a UV-Vis spectrophotometer includes the parameters of accuracy, precision, specificity, linearity, LOD and LOQ. The researchers discovered that the amount of gelatin and carrageenan in paracetamol gummy candy preparations affected the elasticity, pH, and water content. Carrageenan has a dominant influence on boosting pH and water content, while gelatin has a dominant effect on improving flexibility. The best formula had 599,226 mg of gelatin and 400,774 mg of carrageenan.
Comparing Conventional and Modern Methods for The Phycocyanin Extraction from Spirullina sp Marlina, Dian; Purwaningsih, Desi; Pratiwi, Reny; Saputra, Ryan Werytama; Setyaningsih, Widiastuti; Supriyono, Supriyono
Advance Sustainable Science Engineering and Technology Vol. 6 No. 3 (2024): May - July
Publisher : Science and Technology Research Centre Universitas PGRI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26877/asset.v6i3.907

Abstract

Spirulina platensis, a blue-green algae abundant in tropical regions, is rich in minerals, vitamins, fibers, and pigments, with low nucleic acid content. It has unique chromoproteins called phycobiliproteins, notably phycocyanin, used in various applications. This study aims to optimize phycocyanin extraction using different solvents (distilled water and sodium phosphate buffer pH 6.7) and methods (freeze-thaw and sonication). Spirulina platensis biomass was extracted in both solvents, then some of them was freeze for 24 and 48 hours followed by thawing overnight. The other was sonicated for 2.5 minutes, 50 Hz then soaked for 1, 2, and 3 hours. All of the samples were centrifuged at 6000 rpm for 10 minutes and the absorbance was measured using a UV-Vis spectrophotometer at wavelengths of 280, 620, and 650 nm. with freeze-thawing for 48 hours yielded the highest phycocyanin concentration (0.55%), with a yield of 11.07 and purity of 0.21. Sonication improved phycocyanin concentration, yield, and purity significantly, yielding 1.108, 25.85, and 0.26, respectively.
Co-Authors Aji Wahyu Wahiddatul Djakiah Ana Indrayati Aris Tri Jaka Harjanta, Aris Tri Ayu anindia Ayu Rachmawati Bambang Agus Herlambang, Bambang Bowo Sugiharto Destik Wulandari Dewi Ekowati Dwi Ningsih Erna Irawan, Erna Febrian Murti Dewanto Ferina Dyah Prastiyanti Fradine, Chossy Harlita Harlita Haryo Kusumo Heryani, Monalisa I Made Artika I MADE ARTIKA Irawan, Ira Ismi Rahmawati Ismi Rahmawati Isna Jati Asiyah Juliana, Dara Kristina Simanjuntak, Kristina Simanjuntak Kusumo, Haryo Maharani, Novita Mandasari, Mitha Oktavia Marlina, Dian Mega Novita Mega Novita Ningsih, dwi - Nisa, Zaitun Pradana, Arsita Pradana, Arsitya Rahmawati, Ismi Rahmawati, Ismi - Reny Pratiwi Reny Pratiwi Rizky Bimantara HA Ryan Werytama Saputra Saputra, Ryan Werytama Setyaningsih, Widiastuti Simanjuntak, Kristina Siti Aisiyah Sri Hayati, Sri Sri Rejeki Handayani Sri Rejeki Handayani, Sri Rejeki Suharyanto Suharyanto Supriyono Supriyono Supriyono Supriyono Tanzila Rahmi Tita Novarini Tiwuk Susantiningsih Tri Panji Turahman, Taufik Turahman, Taufik Vicky Agus Arwanda Widiastuti Setyaningsih Wulandari, Destik