Claim Missing Document
Check
Articles

Pengaruh Usia dan Dosis Terhadap Efek Samping Penggunaan Metformin pada Pasien Diabetes Melitus Tipe 2 Rawat Jalan dan Rawat Inap Purwoko, Bambang; Chasanah, Uswatun
Jurnal Farmasetis Vol 13 No 2 (2024): Jurnal Farmasetis: Mei 2024
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/far.v13i2.2261

Abstract

Pengelolaan Metformin adalah pilihan pertama untuk agen hipoglikemik oral dan sering dikaitkan dengan reaksi obat yang merugikan (ROM) karena efek samping gastrointestinal seperti diare, mual, muntah, dan perut kembung. Efek samping tersebut dapat dipengaruhi oleh usia, dosis, dan cara penggunaan metformin. Tujuan dari penelitian ini untuk mengetahui hubungan antara faktor usia dan dosis terhadap efek samping metformin pada pasien Diabetes Melitus Tipe 2 di RSUD Cilacap. Penelitian ini merupakan penelitian non-eksperimental dengan menggunakan metode cross sectional. Teknik pengambilan sampel secara purposive sampling dengan sampel sebanyak 96 responden yang memenuhi kriteria inklusi. Pengambilan data dilakukan secara retrospektif dari data rekam medis pasien dan wawancara dengan pasien. Hasil penelitian ini menunjukan bahwa karakteristik responden yang memiliki penyakit DMT2 tertinggi adalah pada jenis kelamin perempuan sebesar (55,21%), umur 56-65 tahun sebesar (42,71%), pendidikan SD sebesar (36,46%), dan pekerjaan IRT sebesar (38,54%). Analisis uji chi square tabel 2x2 digunakan untuk menghubungkan dua variabel. Variabel dari penelitian ini adalah usia, dosis, dan terjadinya efek samping penggunaan metformin. Hasil uji chi square menunjukan dosis metformin berpengaruh terhadap risiko efek samping penggunaan metformin dimana nilai (p<0,05) sedangkan faktor usia tidak berpengaruh terhadap efek samping penggunaan obat metformin dengan nilai (p>0,05). Penggunaan metformin dianjurkan diminum sesudah makan dengan dosis awal rendah untuk mengurangi dan menghindari terjadinya efek samping mual dan perut kembung pada penderita diabetes melitus tipe 2.
Hubungan Lama Terapi dengan Efek Samping Pengobatan TB-MDR Nova, Triyo; Purwoko, Bambang; Mubarok, Fa’iq Hanif
Jurnal Farmasetis Vol 13 No 3 (2024): Jurnal Farmasetis: Agustus 2024
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tuberkulosis Multi Drug Resistance (TB-MDR) merupakan salah satu penyakit yang membutuhkan waktu terapi yang lama (18-24 bulan) dengan efek samping yang banyak. Efek samping yang dialami pasien yaitu artralgia, mual dan muntah, renal, gangguan pendengaran, gangguan tidur, gangguan psikiatri, hipokalemia, hiperurisemia, diare dan nyeri. Tujuan penelitian untuk mengetahui hubungan lama terapi dengan efek samping pengobatan TB-MDR. Penelitian ini dilakukan di RSUD Cilacap dengan desain penelitian observasional deskriptif. Pemilihan subyek penelitian  menggunakan populasi pasien dengan diagnosa TB-MDR yang sesuai dengan kriteria inklusi serta pasien yang mengalami efek samping OAT selama menjalani terapi. Responden yang memenuhi kriteria inklusi ada 49 responden. Pengambilan data secara retrospektif dengan uji Fisher Exact. Lama pengobatan dibagi menjadi pengobatan jangka menengah kurang dari 12 bulan dan pengobatan jangka panjang lebih dari 12 bulan, dengan tingkat efek samping ringan dan berat, didapat 6 pasien jangka menegah (66,7%) dengan efek samping ringan dan sebanyak 3 pasien (33,3%) yang mengalami efek samping berat, 11 pasien jangka panjang (27,5%) dengan efek samping ringan dan 29 pasien (72,5%) dengan efek samping berat. Analisis dengan uji Fisher Exact menunjukkan terdapat hubungan antara lama terapi dengan efek samping obat (p=0,049).
STRATEGI PENGEMBANGAN PRODUK TERHADAP LOYALITAS PELANGGAN MELALUI EKUITAS MEREK DAN CITRA MEREK Nur Hakim, Bagus; Purwoko, Bambang
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 3 No 3 (2019): APRIL
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Product quality, brand equity and brand image are assumed to possess an important role in developing customer loyalty since brand product that has good quality will make the customer loyal. This study is made to find out how far the influence of product quality, brand equity and brand image perception to the loyality of the Nexcare Acne Cover product customer is and what dominant variable that influences customer loyalty. This study is held to 290 consumers of anti acne product of Nexcare Acne Cover. The data processing for this research is Structural Equation Model (SEM) Smart PLS. The study result shows that quality product have influence to brand equity and brand image in Indomaret, Guardian and carrefour, in Guardian brand equity doesn’t have influence to brand image and customer loyalty, brand image have influence to customer loyalty in Indomaret, Guardian and Carrefour. The dominant influence in each account are brand image at Indomaret and Guardian, brand equity at Carrefour.
ANALISIS STRATEGI KORPORAT PENGETAHUAN ASET DAN OPINI PAKAR TERHADAP KINERJA PERUSAHAAN TERBUKA Yuliana, Lingga; WS, Antonius; Purwoko, Bambang
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 1 No 2 (2016): DESEMBER
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The company's performance has been achieved because of the buying and selling activities in the two markets, namely the consumer market and capital markets. In the capital market activities, the company provides stock and bonds and obtain results in the form of earnings per share. This study will analyze the performance of companies based on the value of Price Eaning Ratio and Price to Book Value Ratio. The purpose of this study is to analyze the corporate strategy in the company's performance. This research uses descriptive quantitative approach. This study applies the strategy through the selection of analysis tools that Analytic Network Process (ANP). The results of this study indicate that intensive strategy is best used for the corporate strategy of the firms as engaged in the cement industry. Intensive best strategy is market penetration strategy then market development strategy and product development with the Analytic Network Process (ANP).
ANALISIS STRATEGI FUNGSIONAL TENTANG PENGARUH KOMITMEN DAN PARTISIPASI ANGGOTA TERHADAP KINERJA KOPERASI PEMERINTAH (Studi Kasus Koperasi Pegawai Kementerian Sosial RI) Redjeki, Annie Martina; Purwoko, Bambang; W Sumarlin, Antonius
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 1 No 3 (2017): APRIL
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

onesia’s Cooperative is a basically a legal organization that manages the funds of its members to be put into a good use that caters the needs of the members. This type of organization is a common practice in Indonesia and can be formed byeither mandatory or voluntary membership. This paper investigates the strategic management issues of cooperative that consists of mandatory members because the common practice of this organization only relies on earnings from yields of bank savings / investments and lendings of its members. Questions often raised from this basic activities are whether the cooperative can elevate its portfolios more into non-financial businesses that bear higher yield earnings. In an attempt to answer the preceding, a cooperative set up by the government employees of Ministry of Social Affair is depicted for the object of study. There were 241 workers were stratifiedly sampled in accordance to their civil servant ranks. The distributed questionaires covered the issues of how member’s commitment and member’s participation affect the cooperative’s performances. The indicative results suggest that the commitment of cooperative members can only be increased by members’ participation in order to affect the performance of an organization.
ANALISIS STRATEGI PENINGKATAN PRESTASI KERJA KARYAWAN MELALUI KOMPETENSI DAN KOMITMENT ORGANISASIONAL DALAM PERSPEKTIF PERBANKAN SYARIAH (Study Kasus Pada PT. Bank BTN (Persero),Tbk) Widawati, Fera; Supriyadi, Edy; Purwoko, Bambang
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 1 No 3 (2017): APRIL
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Increasing complexity of business competition and achievement of company performance demands are high demanding role of human resource management. Request a workforce with the skills, knowledge, and skill also increases. Changes in the business environment that occurs leads to the recognition of the importance of human resources as a source of competitive advantage for the Organization, the employee competencies that correspond to the needs of the companies can give impact on the commitment of the employees to achieve the vision and mission of the company is ultimately reflected on the employee's achievements and performance of the company. This research uses three variables, namely competency, organizational commitment, and work achievement. The purpose of this research is to analyze the strategy of increasing employee achievement through organizational commitment and competence as well as composing the SWOT analysis in an effort to the preparation of the strategic plan with regard to the performance of the employee. The research method used was qualitative and quantitative methods. Data processing used in Structural Equation Modelling (SEM). Methods of sampling, cluster sampling is used with the sample number of 245 people. The respondents in this study i.e. all employees in four offices, namely BTN BTN Sharia branch Sunday market, BTN Sharia Branch Office Bogor, BTN Sharia Branch Office Tangerang and Bekasi Branch Office Sharia BTN. Hope the findings of this research is the competence and commitment of organizational impact significantly to achievements of employees and interns based on the SWOT analysis can be formulated strategies to improve employees work achievement with maximize the strengths and minimize the weaknesses and the opportunities and threats so that can becomes a formula for sustainable human resource development that can support the achievement of company performance and have appropriate work achievements with expectations of the company.
ANALISA PENGARUH IKLIM ORGANISASI DAN RASA PERCAYA TERHADAP KOMITMEN KARYAWAN DALAM MENGHADAPI PERUBAHAN STRATEGI PERUSAHAAN (STUDI KASUS PADA PT. SURYAJAYA TEKNOTAMA) Kusuma, Indra; Purwoko, Bambang; Supriyadi, Edy
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 1 No 3 (2017): APRIL
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

In the era of rapid change, the company is required to always be able to face challenges and competitions by making adjustment in strategy. The members of organization's commitment to the strategy chosen by company is very crucial.To support the commitment in company required a good corporate climate and also trust among members of the company. The purpose of this study is to analyze the influence of organizational climate and trust in the commitment of the organization. The study was conducted at PT Suryajaya Teknotama the subjects were employees in that company. The collection of data conducted by interview, studying company documents and using questionnaires. The number of respondents in this study is 202 people. Analysis of the data in this study using SEM and lisrel 8.8 as tools to help analysis the data. Based on the analysis, obtained results showed significant effect of organizational climate to trust, significant effect of trust to commitment. While the organizational climate not significant effect on commitment.
ANALISIS STRATEGI BISNIS PERUSAHAAN ASURANSI KERUGIAN TERHADAP KUALITAS LAYANAN KLAIM BAGI PEMEGANG POLIS ASURANSI KENDARAAN BERMOTOR Firdausi, Irawan; Purwoko, Bambang; Supriyadi, Edy
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 1 No 3 (2017): APRIL
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The development of insurance industry in Indonesia is growing rapidly in the last decade as affected by the improving Indonesian economic conditions, especially in motor vehicle insurance product. These conditions encourage the majority of insurance companies to develop motor vehicles insurance product aggressively and innovatively. One of the crucial factors to be considered public in purchasing a motor vehicle insurance policy is the customer’s expectations for service quality of claim as consideration of the company's business strategy. In this quantitative descriptive study, the author divides the service expectations of claim in three main stages, namely claim acceptance, claim processing, and claim settlement. The aim of this study is to investigate the desired service and the adequate service of claim by the motor vehicle insurance policyholders as factors in the service expectations that affect the quality of service. The survey was conducted for two months, in October - December 2015 with a sample size of 230 people in incidental sampling method. The analytical method used in this research is Structural Equation Model (SEM). Results from this study indicate that the business strategy adopted by insurance companies and service expectations motor vehicle insurance policy holders in each stage of the claims process affect the services quality of claim significantly. Keywords: business strategy, motor vehicle insurance, desired service, adequate service, service expectations, service quality
ANALISIS STRATEGI KINERJA KARYAWAN DI PT. COFFEE TOFFEE INDONESIA Putriawan, Nanda Lestari; Merawati, Endang Ety; Purwoko, Bambang
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 1 No 3 (2017): APRIL
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The main problem in this research is the result of the evaluation of company reports on the performance of employees has decreased from previous years and there are many complaints from employees. The purpose of this study is to analyze the performance of employees through the strategy of transformational leadership, job satisfaction and Organizational Citizenship Behavior. This study uses quantitative and qualitative research with descriptive methods. The results showed that transformational leadership and job satisfaction do not affect the performance of the employees, while the Organizational Citizenship Behavior affect employee performance. Based on the calculation of direct and indirect influence shows a comparison that leads to a more direct influence on the performance of Organizational Citizenship Behavior employee by 0.85 and the indirect effect of transformational leadership on employee performance through the mediation of Organizational Citizenship Behavior as 0.49. This indicator shows that transformational leadership will affect the performance of employees with increased Organizational Citizenship Behavior as mediation. Increase transformational leadership and Organizational Citizenship Behavior note by the management of PT. Coffee Toffee Indonesia as the company's strategy.
ANALISIS STRATEGI FUNGSIONAL DALAM PENGELOLAAN MEREK PROPERTI TERHADAP LOYALITAS PELANGGAN Panjaitan, Lincoln; Purwoko, Bambang; Widyatama Sumarlin, Antonius
EKOBISMAN : JURNAL EKONOMI BISNIS MANAJEMEN Vol 2 No 1 (2017): AGUSTUS
Publisher : SEKOLAH PASCASARJANA PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The purpose of this research was to analyze the functional strategy in marketing mix management and brand management to customer loyalty. In this study used five variables, namely marketing mix, brand, marketing container, customer commitment and customer loyalty. The analysis technique used in this research by using Structural Equation Model (SEM). The data analyzed comes from the distribution of questionnaires to consumers by using accidental sampling technique at PT. Intiland, Tbk located in Tangerang area, which is Talaga Bestari. The results was obtained that there was a positive relationship between marketing mix and brand management on customer loyalty.
Co-Authors Abas, Sofyan Adiguna, Patria Afifah, Laras Agustin, Cahya Tri Ahmad Gamal Ahmad Nur Budi Utama Aji, Lexi Jalu Awwal, Muhammad Al Faridho Azzahra, Aulia Firly Bachtiar, Alfan Baihaqi, Ahmad Noval Cantika O, Azzahra Amanda Chatarina Umbul Wahyuni Dedy Kunhadi DEWI SARTIKA Dewi, Diah Dewi, Tiya Marliyana Edy Supriyadi Efendi, Nofriza Elisa, Verina Elisa Endah Sri Wahyuni Febrinawati, Annisa Tito Firdausi, Irawan Gatot Wijayanto Gingga Prananda Handayawati, Setyorini Heni Pujiastuti Husein Umar I Gusti Ayu Sri Deviyanti Ikhsan, Maulida Nur Ilham, Rachmad Indra Kusuma Iqbal, Iqbal Ramadhan Jata, I Wayan Jayanto, Imam Judijanto, Loso Kharisma, Intan Khuan, Hendri Lestari, Nana Citrawati Lingga Yuliana Makhdum Asqar, Muhabbat Marnoto, Marnoto Merawati, Endang Ety Mislan Sihite, Mislan Moh. Ainul Fais Mubarok, Fa'iq Hanif Mubarok, Fa’iq Hanif Muhammad Aria Wahyudi Nadimah, Amellia Rahma Nur Hakim, Bagus Panjaitan, Lincoln PRIHANTINI Prihartanti, Wiwik Putriawan, Nanda Lestari Rahmanto, Agus Ramadhan, Muhammad Fauzi Redjeki, Annie Martina Rowi, Armein Sjuhary santoso, Ekbal Sanusi, M. Dudi Abdullah Saputri, Maezaroh Afifah Saripudin, Risman Sri Hastutik Sri Widyastuti Stavinibelia Suharjana, I Dewa Ketut Sumantyo, Franciscus Dwikotjo Sri Sumerli A, Chevy Herli Syahril Effendi Syarifah, Laila tapaningsih, weni indah doktri agus Teddy Oswari Tresna, Indra Cahya Triyo Nova, Triyo umi barokah Umpusinga, Hasrun Afandi Uswatun Chasanah Utami, Eva Yuniarti W Sumarlin, Antonius W. Sumarlin , Antonius W. Sumarlin W. Sumarlin, Antonius Wahyunita Yulia Sari, Wahyunita Yulia Wardani, Anastasya Yuntia Eka Widari, Nyoman Sri Widawati, Fera Widyatama Sumarlin, Antonius WS, Antonius Yulianto, Kampono Imam Yuniar, Setyowati Eka Zulkifli Zulkifli Zulkifli