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Beyond BMI: The Synergistic Effect of Ultra-Processed Food Consumption and Sedentary Behavior on Gut Microbiota and Systemic Inflammation in Young Adults with Early Metabolic Syndrome – A Longitudinal Cohort Study Ian Astarina Mas'ud; Yeni Aryani; Restu Auliani; Erba Kalto Manik; Yan Deivita; Ani Laila; Yofa Sukmawati
International Journal of Public Health Excellence (IJPHE) Vol. 6 No. 1 (2026): June-December
Publisher : PT Inovasi Pratama Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55299/ijphe.v6i1.1955

Abstract

Background: Body mass index (BMI) inadequately captures metabolic risks driven by modern lifestyles, particularly the combination of ultra-processed food (UPF) intake and sedentary behavior. While each factor independently fosters low-grade systemic inflammation, their synergistic impact on the gut microbiota–inflammation axis in young adults with early metabolic syndrome (MetS) remains unexplored. Objective: This longitudinal cohort study examined the independent and synergistic effects of UPF consumption and sedentary behavior on gut microbiota composition and systemic inflammatory biomarkers in Indonesian young adults with early MetS over 12 months. Methods: We recruited 400 participants aged 20–30 years meeting 1–2 ATP III criteria for MetS. Dietary intake was assessed with a validated semi-quantitative FFQ with NOVA classification; sedentary time was measured via triaxial accelerometers. Gut microbiota was profiled using 16S rRNA sequencing (V3–V4 region), and hs-CRP, IL-6, and TNF-α were quantified at baseline and 12 months. Participants were stratified into four groups by median splits of UPF energy share (%kcal) and daily sedentary time. Generalized estimating equations tested synergistic interactions on inflammation, and mediation analyses evaluated microbiota diversity pathways. Results: The high-UPF/high-sedentary group exhibited the greatest increases in hs-CRP (+1.78 mg/L), IL-6 (+2.95 pg/mL), and TNF-α (+3.12 pg/mL), with a significant multiplicative interaction (p<0.001). Shannon diversity declined most sharply in the high-UPF/high-sedentary group (−0.32), paralleled by a rise in the Firmicutes/Bacteroidetes ratio (+0.47). Mediation analysis showed that 31.4% of the synergistic effect on hs-CRP was mediated by loss of diversity. Conclusion: Co-occurring high UPF consumption and sedentary behavior synergistically amplify systemic inflammation partly through gut dysbiosis in early MetS, underscoring the need to target both dietary and physical activity domains beyond BMI-centric strategies
Pemeriksaan Kualitas Air dan Pembuatan Filtrasi Air Sederhana di Desa Ajinembah Kec Merek Kabupaten Karo: Pengabdian Risnawati Tanjung; Jernita Sinaga; Helfi Nolia; Susanti br Peranginangin; Marina br. Karo; Restu Auliani
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 5 No. 1 (2026): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 5 Nomor 1 (Juli 2026 -
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v5i1.7313

Abstract

Akses terhadap air bersih masih menjadi permasalahan kesehatan lingkungan di daerah pedesaan, termasuk di Desa Ajinembah. Kualitas air yang buruk berpotensi meningkatkan risiko penyakit berbasis air. Kegiatan pengabdian masyarakat ini bertujuan untuk melakukan pemeriksaan kualitas air serta memberikan solusi melalui pembuatan filtrasi air sederhana. Metode yang digunakan adalah pendekatan partisipatif melalui observasi, inspeksi lingkungan, pengambilan sampel air, serta edukasi kepada masyarakat. Hasil menunjukkan bahwa beberapa sumber air belum memenuhi syarat fisik dan bakteriologis, ditandai dengan kekeruhan dan potensi kontaminasi. Intervensi dilakukan dengan pembuatan alat filtrasi sederhana menggunakan bahan lokal seperti pasir, kerikil, arang, dan ijuk. Setelah kegiatan, terjadi peningkatan pengetahuan dan keterampilan masyarakat dalam menjaga kualitas air. Selain itu, kualitas fisik air menjadi lebih jernih dan layak digunakan. Kegiatan ini menunjukkan bahwa intervensi berbasis masyarakat efektif dalam meningkatkan kesehatan lingkungan.
The Anthropology of Plastic Waste: A Study of Community Adaptation and Resistance to Marine Pollution in a North Javanese Coastal Village Roya Zahir; Safiullah Aziz; Zara Ali; Restu Auliani
Journal of Humanities Research Sustainability Vol. 2 No. 6 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jhrs.v2i6.2787

Abstract

Background. Plastic pollution has become a defining environmental challenge for coastal communities in Southeast Asia, particularly in North Java, where rapid urbanization, industrial activities, and waste mismanagement exacerbate marine degradation. Local communities are not merely passive victims of this ecological crisis; they actively navigate, reinterpret, and resist the social and environmental impacts of plastic waste. Purpose. This study aims to investigate how a North Javanese coastal village adapts to and challenges marine pollution through cultural practices, social organization, and collective environmental action.   Method. An ethnographic research design was employed, integrating participant observation, in-depth interviews, household surveys, and environmental field notes to generate a multi-layered understanding of community responses. Results. The findings reveal three central patterns: first, adaptive behaviors emerge through pragmatic strategies such as waste repurposing and informal recycling networks; second, environmental degradation reshapes local cosmologies and cultural narratives surrounding cleanliness, morality, and human–nature relationships; third, forms of resistance manifest through community-led cleanups, youth environmental activism, and negotiations with local authorities and industries contributing to pollution. Conclusion. The study concludes that community adaptation and resistance are driven by intertwined ecological, economic, and cultural dynamics, illustrating that environmental crises are socially mediated phenomena requiring context-sensitive interventions.    
Application of Appropriate Technology for Clean Water Restu Auliani; Riyanto Suprawihadi; Buschhaus Avinash
Pengabdian: Jurnal Abdimas Vol. 1 No. 1 (2023)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55849/abdimas.v1i1.152

Abstract

Background. The thesis focuses on community service (PkM) conducted by the Ministry of Health Poltekkes institutionally, specifically in the village of Kota Lama II, Secanggang District, Langkat Regency. The study addresses the inadequate access to clean water and poor sanitation conditions in Mr. Mujadi's house, which is among the families included in the PKH (Program Keluarga Harapan) - a conditional cash transfer program in Indonesia. Purpose. The purpose of this community service project is to improve the living conditions of Mr. Mujadi's household by addressing their water and sanitation issues. The project aims to apply science, technology, and art (IPTEKS) through a direct scientific approach to provide sustainable access to clean water and improve sanitation facilities. Method. The objective of this qualitative research is to explore and understand the application of appropriate technology for clean water supply in Kota Lama II Village, Secanggang District, Langkat Regency. The study aims to gain in-depth insights into the experiences, perceptions, and challenges related to the use of appropriate technology for clean water. Results. The results obtained at the end of community service activities in Kota Lama Village II, Secanggang District, Langkat Regency, were built 1 unit of Infiltration galleries. The implementation stages include the initial survey, making Infiltration galleries, compiling filter media, and socializing about clean water and operations and maintenance of Infiltration galleries. Conclusion. Well, water filtered from wells using Infiltration galleries looks clearer and cleaner, odorless and tasteless. This has met the requirements for clean water physically and has met the sanitation aspect.
Penggunaan Pestisida dalam Pertanian: Resiko Kesehatan dan Alternatif Ramah Lingkungan: Pesticide Use in Agriculture: Health Risks and Environmentally Friendly Alternatives Fitriah Suryani Jamin; Dianta Mustofa Kamal; Restu Auliani; Mustar Rusli; Susatyo Adhi Pramono
Jurnal Kolaboratif Sains Vol. 7 No. 11: November 2024 - Jurnal Kolaboratif Sains (JKS)
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/jks.v7i11.6342

Abstract

Penggunaan pestisida dalam pertanian merupakan praktik umum yang meningkatkan hasil panen, namun berpotensi menimbulkan masalah serius terhadap kesehatan manusia dan lingkungan. Penelitian ini bertujuan untuk mengeksplorasi dampak penggunaan pestisida, termasuk risiko kesehatan yang dihadapi petani dan masyarakat, serta pencemaran lingkungan yang ditimbulkannya. Penelitian ini menganalisis berbagai sumber data terkait dampak pestisida dengan menggunakan metode studi literatur, seperti gangguan kesehatan akut dan kronis serta penurunan keanekaragaman hayati. Hasil analisis menunjukkan bahwa meskipun pestisida kimiawi dapat meningkatkan produksi pertanian, penggunaan yang tidak terkelola dengan baik dapat menyebabkan keracunan, pencemaran air, tanah, dan udara, serta degradasi ekosistem. Penelitian ini menyarankan alternatif penerapan metode pengendalian hama terpadu (PHT) dan penggunaan bio-pestisida yang lebih ramah lingkungan. Hasil studi ini diharapkan dapat memberikan wawasan bagi kebijakan pertanian berkelanjutan dan meningkatkan kesadaran akan risiko kesehatan serta lingkungan dari penggunaan pestisida di Indonesia.
Digital Lifestyle Transformation: Implications on Physical Activity and Health of Modern Communities in Medan Province Restu Auliani; Nelson Tanjung; Risnawati Tanjung; Erba Kalo Manik
International Journal of Health, Economics, and Social Sciences (IJHESS) (Special Issue) - International Journal of Health, Economics, and Social Sciences (IJHESS) July 2025
Publisher : Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/ijhess.v7i3.8272

Abstract

The development of digital technology in Medan Province has fundamentally changed people's behavior with increased use of smartphones, tablets, and computers. This study aims to evaluate the empirical relationship between duration of digital device use, physical activity level, and physical and mental health of 18-45 year olds in Medan. Through an online survey of at least 500 respondents recruited by random sampling, data was analyzed using descriptive statistics, Pearson correlation, and linear regression to test hypotheses regarding the influence of digital use on fitness. The results showed a negative correlation between high screen time and physical activity, as well as potential risks of musculoskeletal, sleep disorders, increased BMI, stress and anxiety in intensive users. In contrast, individuals who regularly engaged in ?150 minutes of physical activity per week reported better feelings of health and psychological well-being. These findings confirm the urgency of education-based interventions, digital wellness regulation, and physical activity promotion as strategies to mitigate the negative impacts of digitalization on public health. Recommendations include public health policy programs, integration of healthy lifestyle support technologies, and healthy digital awareness campaigns among Medan residents.
Co-Authors Ambar Kusuma Astuti Andaningsih, IGP Ratih Ani Laila Apsari, Desy Ari Ari Apsari, Desy Augustinus Robin Butarbutar Avinash, Buschhaus Bambang, Th. Teddy Bella Elsaday br Sembiring, Kiki Aprina Buschhaus Avinash Debora Sari Simanjuntak DELI SYAPUTRI Desy Ari Apsar Desy Ari Apsari Desy Lamtiur Kristin Tampubolon Dewi, RD. D. Lokita Pramesti Erba Kalo Manik Erba Kalto Manik Erba Kalto Manik Erba Kalto Manik Erba Kalto Manik Etty Sri Hertini Eva Desembrianita Farlina, Baiq Fina Fitriah S. Jamin Haesti Sembiring Halomoan Manalu, Samuel Marganda Helfi Nolia R. Tambunan Hertini, Etty Sri Ian Astarina Mas'ud IGP Ratih Andaningsih Indriyani Indriyani Indriyani Indriyani Irra Chrisyanti Dewi Judijanto, Loso Julietta Br Girsang Kalto Manik, Erba Kamal, Dianta Mustofa Karo, Marina Br Kristina Br Tarigan Laeli Nur Hasanah Loso Judijanto M. Taher Maha, Jenita Hati Br Manik, Erba Kalo Marina br. Karo Muh Farid Mustar Rusli Mustar Rusli Nampira, Ardi Azhar Nelson Tanjung Nelson Tanjung Nelson Tanjung Nelson Tanjung Novarah Rilestety Peranginangin, Susanti Br Ramdan Yusuf Ramdhan Kurniawan Restiwi Zalukhu Risnawati Tanjung Rissa Megavitry Riswanati Tanjung Riyanto Suprawihadi Roya Zahir Safiullah Aziz Sinaga, Jernita Siregar, Ice Ratnalela Situmorang, Agnes Aldani Soni Suharmono Suharmono, Soni Suprawihadi, Riyanto Susanti Br Perangin-Angin Susanti br Peranginangin Susatyo Adhi Pramono, Susatyo Adhi Swastika Oktavia Syamsu Rijal Syamsul Arifin Tanjung, Nelson Tarigan, Kristina Br Tungga Bhimadi Wiranti, Bhakti Yan Deivita Yeni Aryani Yofa Sukmawati Zara Ali